Posttranscriptional mechanisms of glucocorticoid antiproliferative effects: glucocorticoids inhibit IL-6-induced proliferation of B9 hybridoma cells.

abstract：:We transplanted adult whole bone marrow prelabeled with bromodeoxyuridine (BrdU) into the ischemic boundary zone of the adult rat brain at 1 day after 2 h of middle cerebral artery occlusion (MCAo). Approximately 3.3% of 10(6) transplanted bone marrow cells were BrdU reactive at 14 days after MCAo. BrdU-reactive cells...

journal_title：Cell transplantation

authors： Li Y,Chen J,Chopp M

更新日期：2001-01-01 00:00:00

abstract：:A human embryonic stem cell (HESC) line, H1, was studied after differentiation to a dopaminergic phenotype in vitro in order to carry out in vivo studies in Parkinsonian monkeys. To identify morphological characteristics of transplanted donor cells, HESCs were transfected with a GFP lentiviral vector. Gene expression ...

journal_title：Cell transplantation

authors： Wakeman DR,Weiss S,Sladek JR,Elsworth JD,Bauereis B,Leranth C,Hurley PJ,Roth RH,Redmond DE

更新日期：2014-01-01 00:00:00

abstract：:Stroke is the third leading cause of death worldwide and a huge perpetrator in adult disability. This pilot clinical study investigates the possible benefits of transplanting multiple cells in chronic stroke. A total of 10 consecutive stroke patients were treated by combination cell transplantation on the basis of an ...

journal_title：Cell transplantation

authors： Chen L,Xi H,Huang H,Zhang F,Liu Y,Chen D,Xiao J

更新日期：2013-01-01 00:00:00

abstract：:Stem cells are unique cells in the ability that can self-renew and differentiate into a wide variety of cell types, suggesting that a specific molecular control network underlies these features. To date, stem cells have been applied to many clinical therapeutic approaches. For example, hematopoietic stem cells (HSCs) ...

journal_title：Cell transplantation

authors： Liu SP,Fu RH,Yu HH,Li KW,Tsai CH,Shyu WC,Lin SZ

更新日期：2009-01-01 00:00:00

abstract：:Spinal cord injury (SCI) causes loss of neural functions below the level of the lesion due to interruption of spinal pathways and secondary neurodegenerative processes. The transplant of neural stem cells (NSCs) is a promising approach for the repair of SCI. Reprogramming of adult somatic cells into induced pluripoten...

journal_title：Cell transplantation

authors： López-Serrano C,Torres-Espín A,Hernández J,Alvarez-Palomo AB,Requena J,Gasull X,Edel MJ,Navarro X

更新日期：2016-10-01 00:00:00

abstract：:The main challenge of cell transplantation as a treatment of myopathies is the large amount of tissue to treat. Intravascular delivery of cells may be an ideal route if proven to be effective and safe. Given the importance of nonhuman primates for preclinical research in transplantation, we tested the intra-arterial i...

journal_title：Cell transplantation

authors： Skuk D,Tremblay JP

更新日期：2014-01-01 00:00:00

abstract：:End-stage organ failure is a major cause of death worldwide that can occur in patients of all ages and transplantation is the current standard of care for chronic end-stage disease of many organs. Despite the success of organ transplantation, it is becoming clear that there will never be enough organs made available t...

journal_title：Cell transplantation

authors： Triolo F,Gridelli B

更新日期：2006-01-01 00:00:00

abstract：:Ten mongrel dogs were used in this study. Diabetes was chemically induced in 7 dogs, and 3 dogs served as normal controls. For each diabetic dog, 5 million human bone marrow-derived mesenchymal stem cells/kg were differentiated to form insulin-producing cells using a trichostatin-based protocol. Cells were then loaded...

journal_title：Cell transplantation

authors： Gabr MM,Zakaria MM,Refaie AF,Ismail AM,Khater SM,Ashamallah SA,Azzam MM,Ghoneim MA

更新日期：2018-06-01 00:00:00

abstract：:Autism spectrum disorders (ASDs) are heterogeneous complex neurodevelopmental pathologies defined by behavioral symptoms, but which have well-characterized genetic, immunological, and physiological comorbidities. Despite extensive research efforts, there are presently no agreed upon therapeutic approaches for either t...

journal_title：Cell transplantation

authors： Bradstreet JJ,Sych N,Antonucci N,Klunnik M,Ivankova O,Matyashchuk I,Demchuk M,Siniscalco D

更新日期：2014-01-01 00:00:00

abstract：:Radiotherapy is an effective treatment for brain tumors but often results in cognitive deficits in survivors. Transplantation of embryonic or brain-derived neural stem/progenitor cells (BNSPCs) ameliorated cognitive impairment after irradiation (IR) in animal models. However, such an approach in patients requires a cl...

journal_title：Cell transplantation

authors： Osman AM,Zhou K,Zhu C,Blomgren K

更新日期：2014-01-01 00:00:00

abstract：:New treatment paradigms that slow or reverse progression of chronic kidney disease (CKD) are needed to relieve significant patient and healthcare burdens. We have shown that a population of selected renal cells (SRCs) stabilized disease progression in a mass reduction model of CKD. Here, we further define the cellular...

journal_title：Cell transplantation

authors： Kelley R,Bruce A,Spencer T,Werdin E,Ilagan R,Choudhury S,Rivera E,Wallace S,Guthrie K,Jayo M,Xu F,Rao AN,Humphreys BD,Presnell S,Bertram T

更新日期：2013-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) hold great promise for bone regeneration. However, the power of mesenchymal stem cells has not been applied to structural bone allografts in clinical practice. This study designed a new strategy to enhance the efficiency of allografts for segmental bone regeneration. Isolated MSCs were cu...

journal_title：Cell transplantation

authors： Zou XH,Cai HX,Yin Z,Chen X,Jiang YZ,Hu H,Ouyang HW

更新日期：2009-01-01 00:00:00

abstract：:Magnetic targeting has the potential to enhance the therapeutic effects of stem cells through increasing retention of transplanted cells. To investigate the effects of magnetic targeting intensities on cell transplantation, we performed different magnetic intensities for mesenchymal stem cell (MSC)-targeting therapy i...

journal_title：Cell transplantation

authors： Shen Y,Liu X,Huang Z,Pei N,Xu J,Li Z,Wang Y,Qian J,Ge J

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to identify the beneficial effects of adipose tissue-derived mesenchymal stem cells (ASCs) and ASCs that overexpress the CTLA4Ig gene (CTLA4Ig-ASCs) on established autoimmune thyroiditis and to examine changes in clinical chemistry parameters and the presence of humoral responses upon repeated long-te...

journal_title：Cell transplantation

authors： Choi EW,Lee JM,Lee HW,Yang J,Youn HY

更新日期：2015-01-01 00:00:00

abstract：:Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability. However, the traditional method of expansion and differentiation of hESCs into NPCs in monolayer cultures requires a long time, ...

journal_title：Cell transplantation

authors： Qiu L,Lim YM,Chen AK,Reuveny S,Oh SK,Tan EK,Zeng L

更新日期：2016-01-01 00:00:00

abstract：:Cord blood is an attractive cell source in regenerative medicine and represents an alternative to bone marrow. The aim of this study was to investigate whether human umbilical cord blood mononuclear (HUCBM) cells might be valuable in hepatic regenerative medicine. HUCBM cells differentiated in vitro into hepatocytes, ...

journal_title：Cell transplantation

authors： Alvarez-Mercado AI,Sáez-Lara MJ,García-Mediavilla MV,Sánchez-Campos S,Abadía F,Cabello-Donayre M,Gil A,González-Gallego J,Fontana L

更新日期：2008-01-01 00:00:00

abstract：:Epithelial wound repair assures the recovery of the epithelial barrier after wounding. During wound healing epithelial cells migrate to cover the wound surface. The presented experiments were carried out to compare the migration of human keratinocytes from primary and secondary culture on polystyrene, collagen, and fi...

journal_title：Cell transplantation

authors： Drukała J,Bandura L,Cieślik K,Korohoda W

更新日期：2001-01-01 00:00:00

abstract：:Cell and tissue culture techniques have improved considerably since the first attempts to maintain explants of animal tissue in vitro. The two major developments that have allowed these improvements are the ability to produce continuous cell lines, thus allowing reproducible results to be obtained, and the definition ...

journal_title：Cell transplantation

authors： Clayton HA,London NJ

更新日期：1996-01-01 00:00:00

abstract：:Prior studies have suggested the possibility of immune-mediated death of xenogeneic hepatocytes in a bioartificial liver (BAL) during hemoperfusion. This study was designed to elucidate how immunity may cause death of xenogeneic hepatocytes in the BAL. Healthy dogs were treated with a BAL containing hollow fiber membr...

journal_title：Cell transplantation

authors： Nyberg SL,Amiot B,Hardin J,Baskin-Bey E,Platt JL

更新日期：2004-01-01 00:00:00

abstract：:Cell-based therapy for the bladder has its beginnings in the 1990s with the successful isolation and culture of bladder smooth muscle cells. Since then, several attempts have been made to artificially implant native cell types and stem cell-derived cells into damaged bladders in the form of single-cell injectables or ...

journal_title：Cell transplantation

authors： Gopinath C,Ponsaerts P,Wyndaele JJ

更新日期：2015-01-01 00:00:00

abstract：:Experiments on spinal cord injury (SCI) have largely focused on the transplantation of stem cells into injured spinal cords for motor recovery while neglecting to investigate bladder dysfunction. The present study was performed to investigate the effect of B10 human mesenchymal stem cells (hMSCs) directly transplanted...

journal_title：Cell transplantation

authors： Lee HJ,An J,Doo SW,Kim JH,Choi SS,Lee SR,Park SW,Song YS,Kim SU

更新日期：2015-01-01 00:00:00

abstract：:Bone marrow (BM) cells may interact with coronary endothelium and modulate coronary atherosclerosis. We investigated the time course of coronary luminal loss and changes in conductance after intracoronary injection of enriched hematopoietic BM stem cells in patients with previous myocardial infarction (MI). Among 24 p...

journal_title：Cell transplantation

authors： Vanderheyden M,Vercauteren S,Mansour S,Delrue L,Vandekerckhove B,Heyndrickx GR,Van Haute I,De Bruyne B,Timmermans F,Wijns W,Bartunek J

更新日期：2007-01-01 00:00:00

abstract：:Liver fibrosis is characterized by excessive accumulation of extracellular matrix components in the liver parenchyma that distorts the normal architecture and hepatic function. Progressive fibrosis could end in the advanced stage known as cirrhosis, resulting in the need to resort to liver transplantation. Amniotic me...

journal_title：Cell transplantation

authors： SantAnna LB,Hage R,Cardoso MA,Arisawa EA,Cruz MM,Parolini O,Cargnoni A,SantAnna N

更新日期：2016-12-13 00:00:00

abstract：:In cartilage tissue engineering using stem cells, it is important to stimulate proliferation and control the differentiation of stem cells to specific lineages. Here we reported a combined technique for articular cartilage repair, consisting of bone marrow mesenchymal stem cells (BMMSCs) transfected with connective ti...

journal_title：Cell transplantation

authors： Zhu S,Zhang B,Man C,Ma Y,Liu X,Hu J

更新日期：2014-04-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration in the brain and spinal cord. Progressive paralysis of the diaphragm and other respiratory muscles leading to respiratory dysfunction and failure is the most common cause of death in ALS patients. Respiratory impairment has also been s...

journal_title：Cell transplantation

authors： Garbuzova-Davis S,Shell R,Mustafa H,Hailu S,Willing AE,Sanberg PR,Borlongan CV

更新日期：2020-01-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) displays high resistance to radiation and chemotherapy, due to the presence of a fraction of GBM stem-like cells (GSLCs), which are thus representing the target for GBM elimination. Since mesenchymal stem cells (MSCs) display high tumor tropism, we examined possible antitumor effects of t...

journal_title：Cell transplantation

authors： Kološa K,Motaln H,Herold-Mende C,Koršič M,Lah TT

更新日期：2015-01-01 00:00:00

abstract：:We previously demonstrated that mesenchymal cells from human amniotic membrane (hAMTCs) inhibit the generation and maturation of monocyte-derived dendritic cells (DCs) in vitro. Considering the crucial role of DCs in the immune response and that epithelial cells of the human amniotic membrane (hAECs) share some of the...

journal_title：Cell transplantation

authors： Magatti M,Caruso M,De Munari S,Vertua E,De D,Manuelpillai U,Parolini O

更新日期：2015-01-01 00:00:00

abstract：:Although emerging evidence links mesenchymal stem cells (MSCs) with cancer metastasis, the underlying mechanisms are poorly understood. In the present study, we found that human umbilical cord-derived MSCs (UC-MSCs) promoted MCF-7 cell migration in vitro and metastasis in vivo. To explore the mechanisms, the character...

journal_title：Cell transplantation

authors： Ma F,Chen D,Chen F,Chi Y,Han Z,Feng X,Li X,Han Z

更新日期：2015-01-01 00:00:00

abstract：:Endothelial progenitor cells (EPCs) have been applied for cell therapy because of their roles in angiogenesis and neovascularization in ischemic tissue. However, adverse responses caused by EPC therapy have not been fully investigated. In this study, a human peripheral blood sample was collected from a healthy donor a...

journal_title：Cell transplantation

authors： Lee SH,Ra JC,Oh HJ,Kim MJ,Setyawan EMN,Choi YB,Yang JW,Kang SK,Han SH,Kim GA,Lee BC

更新日期：2019-07-01 00:00:00

abstract：:The effect of tensile stress on the orientation and phenotype of arterial smooth muscle cells (SMCs) cultured in three-dimensional (3D) type I collagen gels was morphologically investigated. Ring-shaped hybrid tissues were prepared by thermal gelation of a cold mixed solution of type I collagen and SMCs derived from b...

journal_title：Cell transplantation

authors： Kanda K,Matsuda T

更新日期：1994-11-01 00:00:00