Abstract：
OBJECTIVE:To review the current treatment and usefulness of lamotrigine in absence seizures. DEVELOPMENT:Absence seizures are classified amongst the generalized epilepsies. They are defined as a transient loss of consciousness of sudden onset and recovery characteristically associated with generalized spike-and-wave discharges on the EEG. In recent years, the epileptic syndromes associated with this type of seizure have been better defined, basically by means of video-EEG studies. The International League Against Epilepsy has recognized four epileptic syndromes with typical absences: absence-epilepsy of childhood, juvenile absence-epilepsy, juvenile myoclonic epilepsy and epilepsy with myoclonic absences. The classical treatment for this type of seizure was based on ethosuximide, or more often, sodium valproate. Sometimes both drugs together were necessary. Other useful drugs are the benzodiazepines such as clobazam. CONCLUSIONS:We review studies of the efficacy and tolerance of lamotrigine in the treatment of absence seizures, one of the groups of seizures in which this drug has been shown to be most effective. Although studies comparing lamotrigine, valproate and ethosuximide are necessary, we emphasize the possibility that lamotrigine may be a drug of choice in absence seizures.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Mauri-Llerda JA,Tejero-Juste C,Iñiguez C,Morales-Asín Fsubject
Has Abstractpub_date
2001-02-01 00:00:00pages
247-50issue
3eissn
0210-0010issn
1576-6578journal_volume
32pub_type
杂志文章,评审abstract：INTRODUCTION:Inappropriate admissions to a hospital service generate unnecessary costs for our health care service. Most admissions to a hospital service come from the emergency department. The presence of a neurologist to attend hospital emergencies would be an important factor allowing admission criteria to be stream...
journal_title：Revista de neurologia
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journal_title：Revista de neurologia
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journal_title：Revista de neurologia
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journal_title：Revista de neurologia
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更新日期：2000-06-01 00:00:00
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