Abstract:
INTRODUCTION:Most patients with Parkinson's disease have cognitive and behavior disorders during the course of their illness. OBJECTIVE:In this study we consider practical aspects of the treatment of patients with Parkinson's disease who have such problems. DEVELOPMENT:Better understanding of both normal and abnormal physiology of the basal ganglia and their connections makes it possible to suggest hypotheses regarding the cause of these disorders. The combination of lesions of multiple subcorticocortical systems with different degrees of direct cortical pathology due to Lewy bodies and neuritic plaques may explain most of the changes, from depression to dementia. CONCLUSIONS:It is necessary to test these concepts using studies based on specific predictions derived from pathophysiological models. Until this is done, the clinical treatment of cognitive and compartmental disorders in Parkinson's disease will continue to be symptomatic, complex and controversial.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Pascual-Leone A,Press Dsubject
Has Abstractpub_date
1999-07-16 00:00:00pages
152-7issue
2eissn
0210-0010issn
1576-6578journal_volume
29pub_type
杂志文章,评审abstract:INTRODUCTION:Strachan's disease is a condition which mainly affects the nervous system. It is characterized by optic, auditory and peripheral neuropathies and lesions of the skin and mucous membranes. In 1955 Miller Fisher gave it this name, since the clinical condition described by Henry Strachan in Jamaica during the...
journal_title:Revista de neurologia
pub_type: 历史文章,杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::A comparative study was carried out to examine urinary excretion of D glucaric acid (DGA), g glutamyltransferase (GGT) activity and the concentration of serum bilirubin as enzymatic induction markers in 89 adult patients (56 men and 33 women) who were receiving chronic treatment with phenobarbital, phenytoin, carbamaz...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-10-16 00:00:00
abstract:TITLE:Consanguinidad y enfermedad mental grave en los primeros Borbones españoles. ...
journal_title:Revista de neurologia
pub_type: 评论,信件
doi:10.33588/rn.7108.2020438
更新日期:2020-10-16 00:00:00
abstract:INTRODUCTION:Pentoxifylline (PTX) is a phosphodiesterase inhibitor which has been found in studies in vitro to inhibit the production of Th-1 cytokines. It has been postulated that it might be used as a possible coadjuvant treatment for interferon in patients with multiple sclerosis. This would also reduce the potentia...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2001-03-16 00:00:00
abstract:INTRODUCTION:Hypnosis is a well known and efficient psychotherapeutic treatment. It has been stated as useful in memory improvement, however, there are only a few reports of this method in teaching, and its neurophysiological aspects. OBJECTIVE:In this paper, the authors were intended to deal with some students' acade...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:INTRODUCTION:For the most part, what makes us different from other animal species is comprised within our brain. However, there is no single factor, no singular reason accounting for the difference between our brain and others; rather, differences appear multiple. DEVELOPMENT AND CONCLUSIONS:Here we perform an up-to-d...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-06-16 00:00:00
abstract::This study reports on the latest advances in childhood headaches that have been made in the last few years, with special emphasis on the important new modifications that have been produced with respect to the previous ones, published in the beta version of the third edition of the International Classification of Heada...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2018-06-05 00:00:00
abstract:INTRODUCTION:This paper review current literature about neurocysticercosis with emphasis on recent advances on diagnosis and therapy. DEVELOPMENT:Cysticercosis is the most common parasitic disease of the nervous system. The disease occurs when humans become the intermediate host in the life cycle of Taenia solium by i...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1999-09-01 00:00:00
abstract:INTRODUCTION:Alterations in SCN1A gene cause most cases of Dravet syndrome. This finding has increased scientific interest in the syndrome, helping to better define its clinical features and facilitating treatment. AIMS:To update the knowledge on Dravet syndrome and to discuss the role of the molecular studies in impr...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-06-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:Reported observations of acquired aphasia in children contain all the symptoms and syndromes that have been described in adult aphasiology. Recovery of colloquial language is good even if anomia and verbal memory deficits persist as the most frequent defects. At long term outcome there are ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract:AIM:To identify the clinical features that predict a favourable response to onabotulinumtoxinA (OnabotA) treatment in patients with refractory migraine. PATIENTS AND METHODS:Retrospective analysis of patients with refractory migraine who underwent at least two pericranial injections of OnabotA between 2008 and 2012. P...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2014-03-16 00:00:00
abstract::By means of the modified trichromic method of Gomori, introduced by Engel and Cunningham in 1963 [1], it has been possible to demonstrate the presence of ragged-red fibers (RRF) in the mitochondrial myopathies. At present, to study these disorders in muscle biopsies, one may also use morphological, ultrastructural, hi...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-04-01 00:00:00
abstract:INTRODUCTION:Virtual reality allows the user to interact with elements within a simulated scene. In recent times we have been witness to the introduction of virtual reality-based devices as one of the most significant novelties in neurorehabilitation. AIM:To review the clinical applications of the developments based o...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-10-16 00:00:00
abstract:INTRODUCTION:The relationship between headache and sleep is complex and runs in two directions. Headache may be the consequence of a (primary or secondary) sleep disorder or its cause (in chronic tension-type headache and/or chronic migraine with or without painkiller abuse). It can also be related to sleep in an intri...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-09-16 00:00:00
abstract:INTRODUCTION:Examination of the special bilingual student (5% of the bilingual student population of the USA) permits us to use not only (1) the statistical reports of the population coefficients and percentages), (2) measurements of progress or performance (age in years or grades of progress at school) and (3) the neu...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract:INTRODUCTION:Genetic etiology in suggested in intracranial aneurysms. Such hypothesis is supported on familial aggregation, ocurrence in identical twins or associated to genetic diseases like adult polycystic renal disease. OBJECTIVE:To identify biological features in familial aneurysms different to sporadic ones. PA...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract:INTRODUCTION:Cystinosis is a hereditary disease with clinical symptoms that are caused by the accumulation of cystine crystals in different tissues. Distal vacuolar myopathy has been reported as one of its later complications. CASE REPORT:Here, we present the case of a 20-year-old male diagnosed with cystinosis at the...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract::Chronic migraine (that is to say, cases where migraine is suffered on 15 or more days per month) is an illness that affects approximately 0.5-2.5% of the population, depending on the statistics that are analysed and the definition of chronic migraine used. The incidence of transformation from episodic to chronic migra...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2012-04-10 00:00:00
abstract:INTRODUCTION:White matter lesions are more prevalent in migraine patients than in the general population, especially those with a high frequency of attacks. A patent foramen ovale has been described as a possible link between migraine and white matter lesions. AIM:To determine the existence of a possible relationship ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:10.33588/rn.7010.2019435
更新日期:2020-05-16 00:00:00
abstract::Taking the characteristics of the ideal antiepileptic drug as the standard, the advantages and disadvantages of the drugs commercially available in recent years-vigabatrin, lamotrigin, gabapentin, and felbamate-are considered from the point of view of their mode of action, pharmacokinetic properties, therapeutic spect...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1996-11-01 00:00:00
abstract:INTRODUCTION:The advantages of care in stroke units (UI) are known, as are those of being in neurology wards as compared with the general medical wards, although to date there are no studies which make a comparative evaluation of the stroke team (EI) as compared with the UI with regard to benefits in care obtained by t...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-01-16 00:00:00
abstract:TITLE:Signo del tridente en la neurosarcoidosis medular. : ...
journal_title:Revista de neurologia
pub_type:
doi:10.33588/rn.7005.2019180
更新日期:2020-03-01 00:00:00
abstract:INTRODUCTION:Oxidative stress increases brain lipid peroxidation, memory and motor deficits and progressive neurodegeneration. Tibolone, a treatment for menopausal symptoms, decreases lipid peroxidation levels and improves memory and learning. AIM:To study the effect of chronic administration of tibolone on lipid pero...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2014-05-16 00:00:00
abstract:INTRODUCTION:Parkinson's disease (PD) is a common neurodegenerative disease which begins in adulthood. Its incidence in Mexico is estimated to be 40-50 cases per 100,000 inhabitants/year and is the fourth reason for medical care in the National Institute of Neurology and Neurosurgery. The protein alpha-synuclein, SNCA,...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-10-16 00:00:00
abstract:OBJECTIVE:To show the disorders of the brain cortical development and the possible origin in base to a large series studied in a Pediatric Neurology service. PATIENTS AND METHODS:A series of 144 children with ages ranging between newborn and 12 years was studied from the clinic, image (MR, 3DMR) and evolutive point of...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2003-08-16 00:00:00
abstract:AIMS:The main objective of this study is to describe the different neuropsychological deficits associated to the consumption of 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy'), as well as the growing evidence that attributes these deficits to the selective axonal damage to serotoninergic cells brought about by th...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2005-07-16 00:00:00
abstract:INTRODUCTION:The determination of human leukocyte antigen (HLA) class II genotype is widely used to confirm the diagnosis of narcolepsy with or without cataplexy. The HLA genotyping is reliable, easy to perform and reassures the clinician. It is also less invasive than other methodologies and is in accordance with the ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-01-16 00:00:00
abstract:INTRODUCTION AND MATERIAL:Nine brains belonging to early onset Alzheimer disease (E280A-PS1 mutation) affected individuals from Antioquia, Colombia, were analyzed by neuropathological standard techniques. All individuals were ascertained from genealogies descendents from a common ancestor that shows a dominant autosomi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:INTRODUCTION:Patients submitted to surgery to treat a brain aneurysm, who have suffered a subarachnoid haemorrhage, sometimes present cognitive disorders that can affect their social, familial, academic or occupational relationships. Memory disorders are frequent, although other cognitive functions may also be affected...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::It was recently suggested that lacunar strokes presenting with headache may be due to large intracranial artery disease. From the stroke database of the Neurology department, Hospital Sta Maria, we retrieved all lacunar strokes who had investigations of the intracranial circulation. Forty seven of the 208 lacunar stro...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00