[Advantages and disadvantages of new antiepileptic drugs].

Abstract:

:Taking the characteristics of the ideal antiepileptic drug as the standard, the advantages and disadvantages of the drugs commercially available in recent years-vigabatrin, lamotrigin, gabapentin, and felbamate-are considered from the point of view of their mode of action, pharmacokinetic properties, therapeutic spectrum and adverse side effects, and indications are given for their prescription and administration so as to improve tolerance when used as monotherapy or in polytherapy, with a table showing the pharmacokinetic interactions which may occur between the older and newer antiepileptic drugs used in polytherapy.

journal_name

Rev Neurol

journal_title

Revista de neurologia

authors

Herranz JL

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

1426-34

issue

135

eissn

0210-0010

issn

1576-6578

journal_volume

24

pub_type

杂志文章,评审
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  • [The Cambridge Cognitive Examination as a tool for detection of dementia].

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    authors: Lozano-Gallego M,Vilalta-Franch J,Llinàs-Reglà J,López-Pousa S

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  • [Duration and objectives of hospital admission to stroke units].

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    authors: Lara M,Díez-Tejedor E,Tatay J,Barreiro P

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    authors: Perea-Bartolomé MV,Ladera-Fernández V,Morales-Ramos F,Pastor-Zapata A

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    doi:

    authors: García-Ruiz Espiga PJ,Echeverría A,García-Torres A,Contreras A

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  • [Neuropathological findings in early-onset Alzheimer's disease (E280a-PS1 mutation)].

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    pub_type: 杂志文章

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    authors: Duque-Castaño A,Roldán MI,Arango-Viana JC,Arcos-Burgos M,Cubillo H,Lopera F

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  • [The evolution of the brain in the genus Homo: the neurobiology that makes us different].

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    doi:

    authors: Martín-Loeches M,Casado P,Sel A

    更新日期:2008-06-16 00:00:00

  • [What is the optimal dose for the prophylactic treatment of chronic migraine patients?].

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    doi:

    authors: Irimia P,Esteve-Belloch P,Murie-Fernandez M,Martinez-Vila E

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  • [Acute necrotizing encephalopathy].

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    journal_title:Revista de neurologia

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  • [Diagnostic value of the criteria of the International Headache Society in the differential diagnosis of primary headaches].

    abstract:INTRODUCTION:In this research we study primary headaches, which are currently considered to be a public health problem. We also examine the fact that an ever increasing number of people are affected and that in some cases such headaches can eventually be disabling because they bring about different degrees of functiona...

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    pub_type: 杂志文章

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    authors: Colina-García RC,Carrasquero-Arias SL,International Headache Society.

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  • [FOXP2 and the molecular biology of language: new evidence. II. Molecular aspects and implications for the ontogenesis and phylogeny of language].

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    pub_type: 杂志文章,评审

    doi:

    authors: Benítez-Burraco A

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  • [Hirayama disease in paediatrics: a clinical case report and review of the literature].

    abstract:INTRODUCTION:Hirayama disease is a rare children's muscular atrophy that affects young Asian males, with muscular atrophy usually in one of the upper limbs that progresses slowly and later stabilises. It is diagnosed by means of electromyographic/electroneurographic with conduction speed studies (EMG/ENG-CS) and by mag...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Martínez-Cayuelas E,Martínez-Salcedo E,Alarcón-Martínez H,Puche-Mira A,Domingo-Jiménez R,de Mingo-Casado P,Serrano-García C

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  • [Parkinson's disease and smoking: coherence and plausibility].

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    doi:

    authors: Allam MF,Campbell MJ,Hofman A,del Castillo AS,Navajas RF

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  • [Neurological assessment of learning disorders].

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    pub_type: 杂志文章,评审

    doi:

    authors: Campos-Castelló J

    更新日期:1998-08-01 00:00:00

  • [Validation of a cognitive complaints questionnaire for young adults: the relation between subjective memory complaints, prefrontal symptoms and perceived stress].

    abstract:INTRODUCTION:Although subjective memory complaints are one of the most common causes behind visits to health services, there are hardly any validated instruments in Spanish for evaluating their magnitude. Since memory complaint questionnaires usually include items referring to attentional and executive aspects, it has ...

    journal_title:Revista de neurologia

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    authors: Lozoya-Delgado P,Ruiz-Sánchez de León JM,Pedrero-Pérez EJ

    更新日期:2012-02-01 00:00:00

  • [Thrombolytic therapy of cerebrovascular disorders].

    abstract:OBJECTIVE:To analyze the available scientific evidence regarding treatment with thrombolytic agents in patients with cerebrovascular disease and present this in the context of daily practice. DEVELOPMENT:Publication of the NINDS study of treatment with t-PA for acute cerebral ischemia led to approval of this treatment...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Estol CJ

    更新日期:1999-12-16 00:00:00

  • [Amimia in Parkinson's disease. Significance and correlation with the clinical features].

    abstract:INTRODUCTION:Reduced facial expression or amimia is one of the most typical characteristics of Parkinson's disease (PD). Despite being described in classic texts, its significance, physiopathology and correlation with motor and non-motor symptoms is largely unknown. PATIENTS AND METHODS:We have studied facial bradykin...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Garcia-Ruiz PJ,Feliz-Feliz CE,Maycas-Cepeda T,Del Val-Fernandez J

    更新日期:2018-01-16 00:00:00

  • [A new surgical treatment for syringomyelia, scoliosis, Arnold-Chiari malformation, kinking of the brainstem, odontoid recess, idiopathic basilar impression and platybasia].

    abstract:INTRODUCTION:Based on medullary traction as responsible for idiopathic syringomyelia (SMI), idiopathic scoliosis (ESCID), Arnold Chiari malformation (ARCH), platybasia (PTB), basilar impression (IMB), odontoid recess (RTO) kinking of the brain stem (KTC) and considering the medullary traction to be transmitted by the f...

    journal_title:Revista de neurologia

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    doi:

    authors: Royo-Salvador MB

    更新日期:1997-04-01 00:00:00

  • [The evaluation of the effects of pharmacological treatment of children with attention deficit hyperactivity disorder].

    abstract::In this study we approach problems related to the dosage and specific action of methylphenidate, its effects at cognitive and social levels, possible side-effects and limitations to its usage, and methods for evaluation of the response to treatment in the school environment. We make special mention of the importance o...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Roselló B,Amado L,Presentación MJ

    更新日期:1999-02-01 00:00:00

  • [The pharmacology of vestibular disorders].

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    authors: Yacovino DA,Hain TC

    更新日期:2004-08-16 00:00:00

  • [The economic impact of epilepsy].

    abstract:AIMS:In this study we review the economic impact involved in suffering from this disease in an attempt to determine how it affects both the individual and society, and the potential benefits deriving from its prevention and treatment. DEVELOPMENT:The World Health Organisation and the World Bank have pointed out that 9...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Pato-Pato A,Cimas-Hernando I,Lorenzo-González JR,Vadillo-Olmo FJ

    更新日期:2004-09-01 00:00:00

  • [Epidemiological features of epilepsy in adults requiring hospital admission].

    abstract:INTRODUCTION AND OBJECTIVES:There are few epidemiological studies specifically directed towards finding the features of the adult epileptic population requiring hospital admission. We proposed to analyze these features in a consecutive series of patients admitted to our department with epilepsy and find the prevalence ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Serrano-Castro PJ,Olivares-Romero J,Guardado-Santervás P

    更新日期:2001-06-01 00:00:00

  • [Dissection of the internal carotid artery with subarachnoid hemorrhage].

    abstract:INTRODUCTION:Dissection of the intracranial arteries is uncommon, forming less than 10% of all cranio-cervical dissections. Apart from the classical clinical findings of extracranial dissections, intracranial dissection may cause subarachnoid haemorrhage (SAH), mainly dissections involving the posterior circulation. C...

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    doi:

    authors: Martín-Bermúdez R,Arenas-Cabrera C,Gil-Néciga E,Jarrín S

    更新日期:1997-06-01 00:00:00

  • [Parkinsonism probably induced by manganese].

    abstract:INTRODUCTION:In all cases of young persons with clinical Parkinson s disease it should be suspected that it is secondary to some primary disorder. Therefore a battery of diagnostic tests should be done before classification as idiopathic Parkinson s disease. CLINICAL CASE:A 31 year old woman whose only previous illnes...

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    doi:

    authors: Durán E,Chacón JR

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  • [Prevalence of neurocysticercosis in individuals affected by epilepsy].

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    pub_type: 杂志文章

    doi:

    authors: Palacio G,Tobón ME,Mora O,Sánchez JL,Jiménez M,Muñoz A,Pineda D,Villa A,Londoño A,Buriticá O,Díaz H,Acebedo S,Giraldo M,Canasteros I,Tobón N,Gómez ME,Arana A,Uribe CS,Tsang V,Pilcher J,Ahn L,Rodríguez M,Hurtad

    更新日期:1997-09-01 00:00:00

  • [The medulloblastoma].

    abstract:INTRODUCTION AND DEVELOPMENT:Medulloblastoma is a cerebellar small cell tumor, whose ancestor cell has not been yet identified in the human normal embriology: its exact origin is, in fact, still unknown. Nevertheless, one of the most acceptable possibilities facing the origin of the tumor is the remaining rests of cere...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Figols-Ladrón de Guevara J,Lafuente-Sánchez JV

    更新日期:2006-08-16 00:00:00

  • [Increase in the incidence of occipital plagiocephaly].

    abstract:INTRODUCTION:The diagnosis and treatment of posterior plagiocephaly is one of the most controversial aspects of craniofacial surgery. PATIENTS AND METHODS:The purpose of this study is to describe a recent increase in the incidence of occipital plagiocephaly without synostosis in our hospital during the last 6 months. ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: González de Dios J,Moya M,Jiménez L,Alcalá-Santaella R,Carratalà F

    更新日期:1998-11-01 00:00:00

  • [Intravenous thrombolytic treatment in acute ischemic stroke: initial results in the Complejo Hospitalario Universitario de Albacete].

    abstract:AIM:To analyze the safety profile and clinical outcome of patients with acute cerebral ischemia who received open treatment with tissue plasminogen activator (rt-PA) in a hospital without previous experience. PATIENTS AND METHODS:This prospective and observational study were realized from January 2004 to January 2007....

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    pub_type: 杂志文章

    doi:

    authors: García-García J,Gracia-Gil J,Sopelana-Garay D,Ayo-Martín O,Vadillo-Bermejo A,Touza B,Peñalver-Pardines C,Zorita MD,Segura T

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  • [Guidelines on the appropriate use of animal models for developing therapies in multiple sclerosis].

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    pub_type: 指南,杂志文章

    doi:

    authors: Moreno B,Espejo C,Mestre L,Suardiaz M,Clemente D,de Castro F,Fernández-Fernández Ó,Montalban X,Villoslada P,Guaza C,Spanish Network for MS.

    更新日期:2012-01-16 00:00:00