Abstract:
:Taking the characteristics of the ideal antiepileptic drug as the standard, the advantages and disadvantages of the drugs commercially available in recent years-vigabatrin, lamotrigin, gabapentin, and felbamate-are considered from the point of view of their mode of action, pharmacokinetic properties, therapeutic spectrum and adverse side effects, and indications are given for their prescription and administration so as to improve tolerance when used as monotherapy or in polytherapy, with a table showing the pharmacokinetic interactions which may occur between the older and newer antiepileptic drugs used in polytherapy.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Herranz JLsubject
Has Abstractpub_date
1996-11-01 00:00:00pages
1426-34issue
135eissn
0210-0010issn
1576-6578journal_volume
24pub_type
杂志文章,评审abstract:INTRODUCTION:Cultural manifestations are frequently used as a source of descriptors in the field of the health sciences. The story of Odysseus (Ulysses) is one of the oldest and most influential works of world literature and has given rise to many subsequent creations, with strong roots in popular culture. AIMS:To con...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:10.33588/rn.7103.2020187
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:The efficiency of Cambridge Cognitive Examination' (CAMCOG) is analyzed as a tool to detect dementias in epidemiological studies. PATIENTS AND METHODS:The data were obtained from subjects who enrolled the second phase on a door-to-door field epidemiological study. The tool used was the 'Cambridge Mental D...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-16 00:00:00
abstract:OBJECTIVE:The epidemiological importance of Acute Cerebrovascular Disorders (ECVA) has led to a need for specific units to care for these patients. We review the effect of these units on Neurology Departments. Development. In the 1970s Stroke Intensive Care Units were created. In the 1980s these units were replaced by ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:INTRODUCTION:Patients submitted to surgery to treat a brain aneurysm, who have suffered a subarachnoid haemorrhage, sometimes present cognitive disorders that can affect their social, familial, academic or occupational relationships. Memory disorders are frequent, although other cognitive functions may also be affected...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::In recent years, image techniques have transformed the diagnosis in Medicine. Nevertheless, they are, by now, far from a widespread clinic and surgical use. Beyond the simple picture inspection, DICOM digital files can be explored by using image analysis/processing techniques in a better way. In practice, clinicians a...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-10-16 00:00:00
abstract:INTRODUCTION:At present, cholinesterase inhibitors constitute the basis for therapy of Alzheimer's disease (AD); these drugs were rationally introduced given the loss of central cholinergic neurotransmission, even though there are many other systems affected in AD, including glutamatergic pathway. DEVELOPMENT:In addit...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-16 00:00:00
abstract:INTRODUCTION AND MATERIAL:Nine brains belonging to early onset Alzheimer disease (E280A-PS1 mutation) affected individuals from Antioquia, Colombia, were analyzed by neuropathological standard techniques. All individuals were ascertained from genealogies descendents from a common ancestor that shows a dominant autosomi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:INTRODUCTION:For the most part, what makes us different from other animal species is comprised within our brain. However, there is no single factor, no singular reason accounting for the difference between our brain and others; rather, differences appear multiple. DEVELOPMENT AND CONCLUSIONS:Here we perform an up-to-d...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-06-16 00:00:00
abstract:INTRODUCTION:OnabotulinumtoxinA (OnabotA) is indicated for headache prophylaxis in patients with chronic migraine. However, there is some controversy about what is the minimum effective dose for treating chronic migraine patients. AIM:To determine the optimal dose of OnabotA for the prophylactic treatment of patients ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-03-10 00:00:00
abstract:TITLE:Encefalopatia necrotizante aguda. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:10.33588/rn.6908.2019113
更新日期:2019-10-16 00:00:00
abstract:INTRODUCTION:In this research we study primary headaches, which are currently considered to be a public health problem. We also examine the fact that an ever increasing number of people are affected and that in some cases such headaches can eventually be disabling because they bring about different degrees of functiona...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-05-16 00:00:00
abstract:INTRODUCTION:FOXP2 is the first gene linked to a hereditary variant of specific language impairment and seems to code for a transcriptional repressor that intervenes in the regulation of the development and the functioning of certain thalamic-cortical-striatal circuits. DEVELOPMENT:In the last three years, significant...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-03-16 00:00:00
abstract:INTRODUCTION:Hirayama disease is a rare children's muscular atrophy that affects young Asian males, with muscular atrophy usually in one of the upper limbs that progresses slowly and later stabilises. It is diagnosed by means of electromyographic/electroneurographic with conduction speed studies (EMG/ENG-CS) and by mag...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Many studies have shown that smoking is lower in patients with Parkinson s disease. However, in other investigations this was not observed. The various studies involved showed wide variation with regard to methodology, criteria for diagnosis and periods of observation and hence it is difficult to compare t...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-04-01 00:00:00
abstract:INTRODUCTION:The neurological concept of learning is approached from a cybernetic point of view, taking into account that a child should recognize a fact, learn it semantically and decided whether it is worth storing; the dynamic aspect of memory is the true motor of the ability to learn and all this is modulated by th...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract:INTRODUCTION:Although subjective memory complaints are one of the most common causes behind visits to health services, there are hardly any validated instruments in Spanish for evaluating their magnitude. Since memory complaint questionnaires usually include items referring to attentional and executive aspects, it has ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To analyze the available scientific evidence regarding treatment with thrombolytic agents in patients with cerebrovascular disease and present this in the context of daily practice. DEVELOPMENT:Publication of the NINDS study of treatment with t-PA for acute cerebral ischemia led to approval of this treatment...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1999-12-16 00:00:00
abstract:INTRODUCTION:Reduced facial expression or amimia is one of the most typical characteristics of Parkinson's disease (PD). Despite being described in classic texts, its significance, physiopathology and correlation with motor and non-motor symptoms is largely unknown. PATIENTS AND METHODS:We have studied facial bradykin...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2018-01-16 00:00:00
abstract:INTRODUCTION:Based on medullary traction as responsible for idiopathic syringomyelia (SMI), idiopathic scoliosis (ESCID), Arnold Chiari malformation (ARCH), platybasia (PTB), basilar impression (IMB), odontoid recess (RTO) kinking of the brain stem (KTC) and considering the medullary traction to be transmitted by the f...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::In this study we approach problems related to the dosage and specific action of methylphenidate, its effects at cognitive and social levels, possible side-effects and limitations to its usage, and methods for evaluation of the response to treatment in the school environment. We make special mention of the importance o...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:In recent years, significant advances have been made in the physiology and the pharmacology of vestibular disorders. It is now possible to elaborate an approximation of the mechanisms of action of the drugs used in the symptomatic treatment of vertigo. DEVELOPMENT:These drugs usually have a number of diff...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-08-16 00:00:00
abstract:AIMS:In this study we review the economic impact involved in suffering from this disease in an attempt to determine how it affects both the individual and society, and the potential benefits deriving from its prevention and treatment. DEVELOPMENT:The World Health Organisation and the World Bank have pointed out that 9...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:There are few epidemiological studies specifically directed towards finding the features of the adult epileptic population requiring hospital admission. We proposed to analyze these features in a consecutive series of patients admitted to our department with epilepsy and find the prevalence ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:Dissection of the intracranial arteries is uncommon, forming less than 10% of all cranio-cervical dissections. Apart from the classical clinical findings of extracranial dissections, intracranial dissection may cause subarachnoid haemorrhage (SAH), mainly dissections involving the posterior circulation. C...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract:INTRODUCTION:In all cases of young persons with clinical Parkinson s disease it should be suspected that it is secondary to some primary disorder. Therefore a battery of diagnostic tests should be done before classification as idiopathic Parkinson s disease. CLINICAL CASE:A 31 year old woman whose only previous illnes...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract:INTRODUCTION:In this investigations, was carried out a neurocysticercosis (NC) prevalence study during seven months in the Instituto Neurológico de Antioquia with the purpose of known neurocysticercosis frequency as cause of epilepsy in patients older than ten years that we attended in our institute. MATERIAL AND METH...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:Medulloblastoma is a cerebellar small cell tumor, whose ancestor cell has not been yet identified in the human normal embriology: its exact origin is, in fact, still unknown. Nevertheless, one of the most acceptable possibilities facing the origin of the tumor is the remaining rests of cere...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-08-16 00:00:00
abstract:INTRODUCTION:The diagnosis and treatment of posterior plagiocephaly is one of the most controversial aspects of craniofacial surgery. PATIENTS AND METHODS:The purpose of this study is to describe a recent increase in the incidence of occipital plagiocephaly without synostosis in our hospital during the last 6 months. ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract:AIM:To analyze the safety profile and clinical outcome of patients with acute cerebral ischemia who received open treatment with tissue plasminogen activator (rt-PA) in a hospital without previous experience. PATIENTS AND METHODS:This prospective and observational study were realized from January 2004 to January 2007....
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:The advance in the achievement of effective therapies for multiple sclerosis (MS), the definition of appropriate therapeutic windows and to establish better diagnostic and prognostic biomarkers have become a challenging task for both researchers and clinicians. Some pitfalls in clinical trials might be rel...
journal_title:Revista de neurologia
pub_type: 指南,杂志文章
doi:
更新日期:2012-01-16 00:00:00