Abstract：
OBJECTIVE:To analyze the available scientific evidence regarding treatment with thrombolytic agents in patients with cerebrovascular disease and present this in the context of daily practice. DEVELOPMENT:Publication of the NINDS study of treatment with t-PA for acute cerebral ischemia led to approval of this treatment for cerebrovascular disease. However, this therapy is associated with a significant frequency of hemorrhagic complications. We analyzed the most relevant studies on the use of thrombolytic drugs. The results of their intravenous and intra-arterial administration were compared with regard to the frequency of recanalization and hemorrhagic complications. We evaluated the results of physician's surveys on the use of t-PA since publication of the NINDS study. These results are interpreted in the context of the potentially generalized use of this treatment. CONCLUSIONS:Although in the NINDS study, administration of i.v. t-PA within three hours of an arterial occlusion resulted in a lower frequency of disability at three months, these results cannot be extrapolated to all medical settings. Until there is a more precise definition of the type of thrombolytic agent, dosage, route of administration, therapeutic window and concomitant use of other drugs, thrombolytic agents should preferably be used in centres specialized in the treatment of cerebrovascular disorders.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Estol CJsubject
Has Abstractpub_date
1999-12-16 00:00:00pages
1301-9issue
12eissn
0210-0010issn
1576-6578journal_volume
29pub_type
杂志文章,评审abstract：INTRODUCTION:Generalised dystonia is an entity that does not usually respond well to medical treatment. Different surgical targets have therefore been used in the treatment of dystonia, including several thalamic nuclei or the internal globus pallidus. The subthalamic nucleus plays a fundamental role in the physiology ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-09-16 00:00:00
abstract：TITLE:Hemorragia vitrea bilateral asociada a hemorragia pontomesencefalica: un caso extremo de sindrome de Terson. : ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-07-15 00:00:00
abstract：AIM:To assess the budget impact of the treatment for relapsing remitting multiple sclerosis (RRMS), interferons, and glatiramer acetate, from the National Health System perspective in Spain. PATIENTS AND METHODS:A budget impact model was designed to compare the cost of RRMS treatment in different settings, using a fiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：AIM:To present seven tumors of the cerebral hemispheres in 6 children with neurofibromatosis type 1 (NF1). PATIENTS AND METHODS:Six patients (three males and three females) of 600 cases of a series with NF1 showed features of cerebral hemispheres tumor (seizures, headache and hemiparesis). They were studied neurologic...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2010-04-16 00:00:00
abstract：:Subcutaneous nodules and neuropsychiatric complications are the most relevant adverse effects during apomorphine infusion treatment. Subcutaneous nodules appear in almost all the patients and accurate information and training of both patient and caregiver is essential to minimise their impact on the treatment. Althoug...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:As result of our aim to improve the quality standard of our emergency system, work has been carried out in relation to the development and monitorization of effective clinical protocols in the department of paediatric practice. PATIENTS AND METHODS:An evidence based review approach was taken to design a c...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-08-16 00:00:00
abstract：INTRODUCTION:Congenital insensitivity to pain with anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV (HSAN IV) is a rare autosomal recessive disorder featuring recurrent fever episodes, inability to sweat, absent response to noxious stimuli, self mutilating behavior and mental retardation. It has...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-08-16 00:00:00
abstract：AIM:To analyse the data and concepts that have been produced in relation to one of the functions that have been suggested for sleep, namely, neuronal recovery. DEVELOPMENT:Sleep is a state of consciousness that is different to that of arousal. Mammals devote an important part of their lives to sleeping; for example, a...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-10-01 00:00:00
abstract：TITLE:Encefalitis multifocal como manifestación neurológica de la infección por COVID-19. ...
journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.7109.2020226
更新日期：2020-11-01 00:00:00
abstract：INTRODUCTION:In recent years the demand for ambulatory neurological care has risen. Studying this situation can help to improve health care planning and the quality of the referrals from primary care. AIM:To analyse a number of variables involved in the first visits referred from primary care to neurology services. P...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
abstract：:Today, the fact that sensory integration difficulties with a neurological basis exist and that they seriously condition the development of those individuals who suffer from them is widely accepted and acknowledged as being obvious by the vast majority of professionals working in the field of community healthcare. Howe...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：2017-02-24 00:00:00
abstract：:The Minimental State Examination (MMSE), created in 1975 as a tool for briefly evaluating the patient's mental state, has been widely used and is the most frequently cited cognitive test on Medline, as well as being the one with the most versions in different languages (over 70). Through a review of the Medline databa...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2015-10-16 00:00:00
abstract：INTRODUCTION:Transcranial Doppler (TCD) is a new technique which is becoming increasingly used in neurology and is highly dependent on the user. OBJECTIVE:To evaluate the reliability of TCD in our hospital. PATIENTS AND METHODS:During a five month period, all patients who had a cerebral angiogram done, also had DTC w...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-09-16 00:00:00
abstract：INTRODUCTION:Unilateral or bilateral agenesis of the internal carotid artery has not often been described in children since it is usually asymptomatic. CLINICAL CASE:We describe a case of isolated unilateral agenesis of the internal carotid artery in a child of 20 months old who presented with two episodes of status c...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：:The term 'epileptic equivalent' has had different meanings in recent years, for both doctors and lawyers (who have copied their reports). Our interest is due to finding that in the jurisprudence of the Supreme Court that we have reviewed, these terms are still taken into consideration when passing judgement or declari...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：AIM:To identify the clinical and psychosocial factors of a Colombian cohort of patients with juvenile myoclonic epilepsy and its relation to crisis control. PATIENTS AND METHODS:Retrospective cohort study of patients over 14 years of age with a diagnosis of juvenile myoclonic epilepsy, with 12 months of follow-up in a...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.6911.2019305
更新日期：2019-12-01 00:00:00
abstract：TITLE:Parálisis súbita de la supraversión de la mirada en una niña de 9 años. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.7110.2020275
更新日期：2020-11-16 00:00:00
abstract：INTRODUCTION:Parkinson's disease (PD) is characterized by motor symptoms such as bradykinesia, rigidity, alteration of postural reflexes and tremor at rest and other non-motor symptoms such as changes in sleep patterns and sexual behavior. However, little is known about paraphilic sexual behaviors. AIM:To summarize th...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-08-16 00:00:00
abstract：:The Landau-Kleffner syndrome consists of the association of paroxysmal EEG abnormalities, more marked during sleep, acquired aphasia usually of receptive type, and epileptic seizures in three quarters of cases. Additional features include behavioral disturbances that may even present with autistic features, cognitive ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-08-16 00:00:00
abstract：INTRODUCTION:Checkpoint inhibitors have dramatically transformed cancer treatment. However, due to the increasing number of tumors in which they are used, there is a high number of reported adverse effects. Among them, we highlight neurological side effects. In the approbatory clinical trials, they were thought to be s...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：10.33588/rn.6807.2019022
更新日期：2019-04-01 00:00:00
abstract：INTRODUCTION:A spinal cord injury implies the loss of or alteration to the gait pattern. Stimulating the pattern generating centres in the sublesional spinal cord determines the appearance of flexion and extension automatisms that are useful for gait training in patients with spinal cord injuries. These centres can be ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：INTRODUCTION:The clinical diagnosis of encephalitis due to anti-glutamate receptor N-methyl D-aspartate (NMDA) antibodies (anti-NMDA encephalitis) is made more complex by the fact that psychiatric clinical features are usually predominant in the early stages. This can lead to a delay in the diagnosis, treatment and pro...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2012-04-16 00:00:00
abstract：INTRODUCTION:Neuroschistosomiasis is an uncommon and under diagnosed disease in our country because of the no clinical suspicion. The most common neurological manifestations are epileptic seizures as central nervous system involvement or different types of myelopathies: transverse myelitis, myeloradiculopathy, cauda eq...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-02-01 00:00:00
abstract：TITLE:Hematoma subdural cronico calcificado: cerebro blindado. : ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2014-05-01 00:00:00
abstract：INTRODUCTION:Fractures of the odontoid process make up between 10 and 15% of all cervical fractures. The decision as to when to operate on them is still controversial; the dilemma as to whether to use surgical or conservative treatment is still a problem. PATIENTS AND METHODS:We designed a descriptive study, which was...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：INTRODUCTION:The ganglioside GM1 has been shown to be effective in the treatment of experimental cerebral ischemia. Gangliosides from bovine brain have not been used in the treatment of ischemic cerebral accidents. There is evidence suggesting that they may also be effective. RESULTS:Ten minutes of bilateral occlusion...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION AND AIMS:Parasomnias have been little studied in prepubertal age children. When it happens often they can alter the continuity of the sleep and reduce the value restorer of this affecting the academic functioning and daytime behavioural in younger children. We study the total frequency of the parasomnias, ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:Several studies have found that individuals with multiple sclerosis (MS) experience relatively high rates of anxiety and depression; however, there are few reports about social anxiety in individuals with MS. AIM:To analyze the prevalence of social anxiety disorder and other psychiatric comorbidities in M...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.7002.2019213
更新日期：2020-01-16 00:00:00
abstract：INTRODUCTION:Many studies have shown that smoking is lower in patients with Parkinson s disease. However, in other investigations this was not observed. The various studies involved showed wide variation with regard to methodology, criteria for diagnosis and periods of observation and hence it is difficult to compare t...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
abstract：INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-10-16 00:00:00
