Abstract：
INTRODUCTION:The clinical diagnosis of encephalitis due to anti-glutamate receptor N-methyl D-aspartate (NMDA) antibodies (anti-NMDA encephalitis) is made more complex by the fact that psychiatric clinical features are usually predominant in the early stages. This can lead to a delay in the diagnosis, treatment and prognosis of the disease. CASE REPORTS:We report on two clinical cases attended by the Child/Youth Psychiatry Section of our hospital, in collaboration with the Paediatric and Neurology services. Case 1: a 4-year-old male who was referred owing to behavioural alterations and the regression of previously acquired skills. Case 2: a 13-year-old female who was admitted due to a behavioural disorder within the context of a possible initial psychotic episode. In both cases appropriate complementary tests were performed, including lumbar puncture and anti-NMDA antibodies, which were positive. Once the diagnosis of anti-NMDA encephalitis had been reached, treatment was started: in the first case, with intravenous perfusion of corticoids and immunoglobulins, while in the second rituximab had to be associated. Both patients progressed towards clinical improvement. CONCLUSIONS:Over the last two years there has been an increase in the number of cases of anti-NMDA encephalitis diagnosed in the child/youth population. It is a neuropsychiatric, autoimmune condition, which can correspond to a paraneoplastic syndrome. Follow-up and transvaginal ultrasonography as well as thoracoabdominal computerised axial tomography scans are recommended for at least two years after diagnosis. Early diagnosis and treatment are important, which means that a multi- and interdisciplinary approach is required.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Casanova-Gracia N,Banzo-Arguis C,Sanz-Asin P,Zapata-Usabel M,Jordana-Vilanova N,Cortina-Lacambra MTsubject
Has Abstractpub_date
2012-04-16 00:00:00pages
475-8issue
8eissn
0210-0010issn
1576-6578pii
rn2011516journal_volume
54pub_type
杂志文章abstract：INTRODUCTION:Unilateral or bilateral agenesis of the internal carotid artery has not often been described in children since it is usually asymptomatic. CLINICAL CASE:We describe a case of isolated unilateral agenesis of the internal carotid artery in a child of 20 months old who presented with two episodes of status c...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：:The most relevant data presented at the 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), held in October 2013 in Denmark, were summarised at the sixth edition of the Post-ECTRIMS Expert Meeting held in Madrid in October 2013, resulting in this review, which is being p...
journal_title：Revista de neurologia
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doi：
更新日期：2014-10-16 00:00:00
abstract：:Today, the fact that sensory integration difficulties with a neurological basis exist and that they seriously condition the development of those individuals who suffer from them is widely accepted and acknowledged as being obvious by the vast majority of professionals working in the field of community healthcare. Howe...
journal_title：Revista de neurologia
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doi：
更新日期：2017-02-24 00:00:00
abstract：INTRODUCTION:Opsoclonus myoclonus is a rare neurological syndrome affecting children and adults, and which is characterised by a sudden onset of chaotic eye movements and myoclonias. In children it generally appears before the age of three as a parainfectious or paraneoplasic process; the type of tumour most frequently...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-08-16 00:00:00
abstract：:Although infrequent, one of the etiological causes of aseptic meningoencephalitis is drug-induced. In our patient, two cases of meningocephalitis took place over a period of six years, together with a meningismus following consumption of trimetroprim-sulphametoxazol (cotrimoxazol). Features of the cases were mental co...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:The subarachnoid haemorrhage non traumatic assumes between the 6-8% of all acute cerebrovascular, besides is more frequent in young persons. The mortility and mortality is high and the predictive factors of the worse prognostic in unknown. MATERIAL AND METHODS:In the present work, we realized a study of t...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：INTRODUCTION:Traumatic brain injury (TBI) is a common cause of death and disability in the paediatric population, although the literature on the Spanish population is scarce. From the perspective of early vulnerability, recent research findings suggest that early brain injury has worse sequelae and a higher risk of imp...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.7007.2019393
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abstract：:X-linked adrenoleukodystrophy is the prototype of the disorders that involve a single peroxisomal protein, and it is by far the most common peroxisomal disorder. The gene that is defective in this disorder is a peroxisomal membrane protein involved, in an as yet undefined manner, in the degradation of very long chain ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:The author reviews the value of the electrophysiological techniques: electromyography (EMG), electroneurography or motor and sensitive nerve conduction velocity (MCV, SCV), brainstem auditory potentials (BAER), visual evoked potentials (VEP) and electroretinography (ERG), somatosensory evoked potentials (SEP)...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：INTRODUCTION:In recent years the demand for ambulatory neurological care has risen. Studying this situation can help to improve health care planning and the quality of the referrals from primary care. AIM:To analyse a number of variables involved in the first visits referred from primary care to neurology services. P...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
abstract：AIMS:To evaluate the presence of epileptiform discharges and the organisation of nocturnal sleep of autistic children without nocturnal polysomnographic epileptic seizures. SUBJECTS AND METHODS:Cross section analysis. SUBJECTS:21 boys and girls with autistic spectrum using DSM IV criteria between the ages of 4 and 12...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-06-16 00:00:00
abstract：INTRODUCTION:Leprosy is an infectious disease caused by the bacteria Mycobacterium leprae. It is particularly prone to affect the skin and the nerve trunks and, in fact, both are compromised in most infected patients. It is transmitted by exposure to those with the disease and sometimes by reactivation. One uncommon po...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2016-09-16 00:00:00
abstract：INTRODUCTION:The impossibility of treating patients with sleep disorders adequately means that, as specialists, we have to look for new pharmacological treatments and for this reason we examined the information in the paper by Salin Pascual (1999) about the increase in deep sleep when olanzapine is used as an antipsych...
journal_title：Revista de neurologia
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:Autonomic dysfunction is a common manifestation in patients with in Parkinson's disease, which can sometimes precede motor impairment. It can be expressed as orthostatic and postprandial hypotension, supine hypertension, hypersalivation, constipation, delayed gastric emptying, dyshidrosis, bladder and sexual dysfuncti...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 历史文章,杂志文章
doi：
更新日期：2000-07-16 00:00:00
abstract：:A patient developed enlarged Gerstmann syndrome after left thalamic haematoma. Single photon emission computerised tomography (SPECT) showed left parietal-temporal cortical hypocapture. These findings would lead us to believe that the clinical picture of our patient was due to a thalamic-cortical diaschitic phenomenon...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：INTRODUCTION:In the treatment of speech disorders by means of speech therapy two antagonistic methodological approaches are applied: non-verbal ones, based on oral motor exercises (OME), and verbal ones, which are based on speech processing tasks with syllables, phonemes and words. In Spain, OME programmes are called '...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Late preterm infants currently constitute 70% of preterm infant births. They present greater comorbidity, including neurodevelopment disorders, which may not manifest until the school age. AIM:To identify the existence of difficulties in the neurodevelopment at the age of two years. SUBJECTS AND METHODS:...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.6812.2018360
更新日期：2019-06-16 00:00:00
abstract：INTRODUCTION:Parkinson's disease (PD) is characterized by motor symptoms such as bradykinesia, rigidity, alteration of postural reflexes and tremor at rest and other non-motor symptoms such as changes in sleep patterns and sexual behavior. However, little is known about paraphilic sexual behaviors. AIM:To summarize th...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-08-16 00:00:00
abstract：:Magnetic resonance is the most sensitive para-clinical method available for the diagnosis of multiple sclerosis since it shows changes in 95% of the patients with clinically definite multiple sclerosis. However, little correlation has been found, in different studies, between the parameters of magnetic resonance and t...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-16 00:00:00
abstract：INTRODUCTION:Sciatic nerve paralysis is a rare entity in the newborn. Few reference in specialized tests indicate that in the majority of cases the sciatic palsy has been observed after misplaced injections into the buttocks. The prognosis is variable and appears to be better after umbilical vessel catheterization for ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：INTRODUCTION:Akinetic mutism is considered as an alteration of the motivational state of the person, which the patient is unable to initiate verbal or motor responses voluntary, even with preserved sensorimotor and surveillance functions. CASE REPORT:A 43 year-old male involved in a cerebellum arteriovenous fistula co...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2017-01-16 00:00:00
abstract：INTRODUCTION:Oxidative stress increases brain lipid peroxidation, memory and motor deficits and progressive neurodegeneration. Tibolone, a treatment for menopausal symptoms, decreases lipid peroxidation levels and improves memory and learning. AIM:To study the effect of chronic administration of tibolone on lipid pero...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2014-05-16 00:00:00
abstract：INTRODUCTION:Alpha interferons (IFN a) have been shown to be effective in patients with chronic active hepatitis C. IFN a treatment may be associated with neurologic complications, including peripheral neuropathy. CASE REPORT:We describe a patient with active hepatitis C treated with IFN a, who developed peripheral ne...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-10-01 00:00:00
abstract：INTRODUCTION:Pentoxifylline (PTX) is a phosphodiesterase inhibitor which has been found in studies in vitro to inhibit the production of Th-1 cytokines. It has been postulated that it might be used as a possible coadjuvant treatment for interferon in patients with multiple sclerosis. This would also reduce the potentia...
journal_title：Revista de neurologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-03-16 00:00:00
abstract：INTRODUCTION:Epilepsy and the epileptic syndromes are common neurological diseases and represent an important public health problem that has given rise to marked social and healthcare concerns. AIM:To analyse the changes in the consumption of antiepileptic drugs in the Basque Country Autonomous Community over a 13 yea...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-04-16 00:00:00
abstract：INTRODUCTION:Episodes of recurrent bacterial meningitis can occur in patients due to either congenital or acquired disorders. Congenital deformity of the bony labyrinth can be linked to a fistulous tract communicating it with the intracranial subarachnoid space. Mondini deformity is a frequent malformation in congenita...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-11-16 00:00:00
abstract：INTRODUCTION:Normal persons, whatever their level of education, have innate basic mathematical ability, but this is very sensitive to deterioration of cognitive function. The tests currently available do not permit evaluation of this ability in patients who cannot read or have little education. The coin test (CT) was d...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：:We studied 56 patients, 30 women and 26 men ranging from 30 to 79 years of age (average age 64.5 +/- 10.4), who were admitted to our hospital between 1982 and August 1995 with clinical features compatible with occlusion at the level of the bifurcation of the basilar artery. The patients were selected following clinica...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
