Abstract:
:Autonomic dysfunction is a common manifestation in patients with in Parkinson's disease, which can sometimes precede motor impairment. It can be expressed as orthostatic and postprandial hypotension, supine hypertension, hypersalivation, constipation, delayed gastric emptying, dyshidrosis, bladder and sexual dysfunction. It impairs the quality of life of patients and complicates the management of motor symptoms. Evidence available to treat complications is low. Our aim is to review the pathophysiology and clinical features of autonomic dysfunction in Parkinson's disease and provide a practical approach to handling the available evidence. TITLE:Manejo de la disfuncion autonomica en la enfermedad de Parkinson. :Resumen. La disfuncion autonomica es una manifestacion frecuente en los pacientes con enfermedad de Parkinson, que, en ocasiones, puede preceder a la afectacion motora. Se manifiesta en forma de hipotension ortostatica y posprandial, hipertension supina, sialorrea, estrenimiento, retraso del vaciamiento gastrico, dishidrosis, disfuncion vesical y sexual. Repercute significativamente en la calidad de vida de los enfermos, complicando el manejo de los sintomas motores. La evidencia disponible para el tratamiento de la mayoria de las complicaciones es escasa. Nuestro objetivo es revisar las caracteristicas fisiopatologicas y clinicas de la disfuncion autonomica en la enfermedad de Parkinson y aportar un enfoque practico en su manejo segun la evidencia disponible.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Crespo-Burillo JA,Alarcia-Alejos Rsubject
Has Abstractpub_date
2015-04-16 00:00:00pages
355-64issue
8eissn
0210-0010issn
1576-6578pii
rn2014341journal_volume
60pub_type
杂志文章,评审abstract:OBJECTIVE:To present a case with several cutaneous hemangiomas associated with intracranial hemangiomas and possibly with an intrahepatic hemangioma. CASE REPORT:A boy, 17 months old, showing several cutaneous hemangiomas and epileptic seizures resisting to antiepileptic medication, who also presented psychomotor reta...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:INTRODUCTION:Dissection of the intracranial arteries is uncommon, forming less than 10% of all cranio-cervical dissections. Apart from the classical clinical findings of extracranial dissections, intracranial dissection may cause subarachnoid haemorrhage (SAH), mainly dissections involving the posterior circulation. C...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract:INTRODUCTION:Glutaric aciduria type I is an autosomal recessive inborn error of metabolism that is due to a deficiency of the enzyme glutaryl-CoA dehydrogenase, which gives rise to an accumulation of glutaric and 3-hydroxyglutaric acids in biological fluids. Clinical features present as a sudden-onset severe neurologic...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-05-16 00:00:00
abstract:AIM:To evaluate the efficiency of topiramate (TPM), an antiepileptic medication (AEM) which possesses multiple mechanisms of action and good pharmacokinetics, in the different types of childhood epilepsy and to make an appraisal of its value in migraines, bipolar disorder, eating disorders and neuropathic pain, accordi...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract:INTRODUCTION:Virtual reality allows the user to interact with elements within a simulated scene. In recent times we have been witness to the introduction of virtual reality-based devices as one of the most significant novelties in neurorehabilitation. AIM:To review the clinical applications of the developments based o...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-10-16 00:00:00
abstract:INTRODUCTION:The Aragon Stroke Care Plan (PAIA) was created in 2008 within the framework of the Spanish National Health System. Monitoring hospital care of strokes by means of periodic audits was defined as one of its lines of work. AIM:To determine the quality of the hospital care process for stroke patients in Arago...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-07-16 00:00:00
abstract:INTRODUCTION:Diagnosing Alzheimer's disease (AD) as soon as possible is critical to achieve an effective treatment of patients. AIM:To make up a test capable of differentiating those patients suffering from the early stages of AD compared to healthy people or patients with mild cognitive impairment (MCI). SUBJECTS AN...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-04-16 00:00:00
abstract:INTRODUCTION:Behavior disorders are frequently seen in children attending a neuropaediatric clinic. The classical neuroleptic drugs are usually used for treatment. However response tends to be irregular with adverse effects at a cognitive level and extrapyramidal symptoms. PATIENTS AND METHODS:We started to use risper...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::The established risk factors for ischemic stroke do not sufficiently explain all clinical and epidemiological features of the disease, such as the winter peak of stroke incidence, the decline of stroke during this century and the time point of cerebral ischemia. A role of infectious disease as stroke risk factor may p...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:Attention deficit hyperactivity disorder (ADHD) is one of the most frequently observed processes in our Neuropaediatric unit, and in recent years has become one of the leading reason for visits, together with headaches. On occasions, the diagnosis that should be made, in accordance with the...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract:INTRODUCTION:Severe infection by SARS-CoV-2 has shown to entail an increased risk of thrombotic, especially venous, events. Central venous catheters have also been associated with an increased risk of thrombotic complications. Paradoxical embolism as an aetiological mechanism of ischaemic stroke should be considered in...
journal_title:Revista de neurologia
pub_type:
doi:10.33588/rn.7105.2020317
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION:Restless legs is an unpleasant sensation in the calves that occurs when the individual is sitting or laying down, with an irresistible urge to move the legs. It has been know as a cause of insomnia. We have been using various drugs with a variety of effectiveness. Levodopa is now considered the drug of cho...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-05-16 00:00:00
abstract:INTRODUCTION AND AIMS:Parasomnias have been little studied in prepubertal age children. When it happens often they can alter the continuity of the sleep and reduce the value restorer of this affecting the academic functioning and daytime behavioural in younger children. We study the total frequency of the parasomnias, ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:Dystonia is defined as a sustained co-contraction of agonistic and antagonistic muscles that can cause twisting, twitching and abnormal postures. Occupational dystonias are included in a special group of pathologies that are secondary to a repeated effort related to the professional activity carried out by...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To show the neurological disorders associated with ocular changes mainly affecting retina and which can be seen during the first year of age. DEVELOPMENT:It is used the personal experience and the reported papers of the literature related with the subject to make a short review of the main neurological, bioc...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:Neuronal ceroid lipofuscinosis (NCL), represents a group of inherited neurodegenerative disorders. Based on the age of the patient at onset, clinical course and ultrastructural morphology it has been identified three clinical types for the pediatric group: 1) Infantile NCL (INCL); 2) Late infantile NCL (LI...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:Myasthenia gravis is an autoimmune disease of the neuromuscular junction that presents clinically as fluctuating weakness of skeletal muscles, as of the ocular region (myasthenia ocular). AIM:To demonstrate that the sensitivity and specificity of the ice pack test are high, in the differential diagnosis o...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:The literature on clinical and physiophatologic characteristics of the spectrum of memory disorders in childhood is reviewed in this article. DEVELOPMENT:There are only a few detailed reports of permanent specific memory disorders in children. Early anoxo ischaemic bihippocampal injuries can cause a selectiv...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract:INTRODUCTION:The current advances in the field of human genetics allow for the development of alternative therapies for the treatment of diseases affecting the central nervous system (CNS). One of the most promising new therapies is the use of therapeutic genes or gene therapy. OBJECTIVE:To briefly review the recent a...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-07-16 00:00:00
abstract:INTRODUCTION:People with a fibromyalgia diagnosis complain of having very poor cognitive functioning. In recent years, there has been an increasing interest to investigate which cognitive impairment is present in this disease. AIM:To review the published research on fibromyalgia and cognitive dysfunction. DEVELOPMENT...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2013-06-01 00:00:00
abstract:INTRODUCTION:Epilepsy is a chronic disease with high prevalence. Its impact in the quality of life is influenced by factors like disease characteristics, comorbidities, stigma perception and treatment adherence. AIM:To assess the quality of life, the social stigma and the treatment adherence of patients with epilepsy ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2018-10-16 00:00:00
abstract:INTRODUCTION:Autism spectrum disorders (ASD) are neurodevelopmental disorders that affect social communication and present stereotypic behaviours. Comorbidity associated to conduct disorders is frequent, starts in infancy and, in general, continues into adulthood. It is sometimes associated with aggressiveness, negativ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION:The early years of life, more especially the first three, are dominated by a series of anatomical-functional facts that express the progressive enrichment of behaviour through the process of neurological maturation, which is expressed as reaching the maximum level of functioning at each stage of developmen...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2013-09-06 00:00:00
abstract:INTRODUCTION:Non-ketotic hyperglycinemia is a congenital error in the breakdown of glycine. The most common type is the classical neonatal form, which begins at the age of a few days with symptoms of lethargy, hypotonia, myoclonia, convulsions, apneas and, frequently, ends in death. Survivors usually develop intractabl...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-10-16 00:00:00
abstract::The HMG-CoA reductase inhibitors (known as statins) have been shown to reduce morbi-mortality of vascular origin, including transitory ischemic accidents and cerebral infarcts, in a large group of patients. The implications, both clinical and of costs, oblige us to consider analysis of the existing evidence and the an...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-11-01 00:00:00
abstract:INTRODUCTION:In clinical practice, it is common to find cases of epileptic women being treated with antiepileptic drugs (AEDs) whom we have to advise on the compatibility of these AEDs with breastfeeding. AIMS:In order to offer correct guidance, we must be well informed about the pharmacokinetic characteristics of the...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:10.33588/rn.6902.2019037
更新日期:2019-07-16 00:00:00
abstract:INTRODUCTION:Addiction to drugs is a chronic illness with severe repercussions for those that consume them and to date has no known cure. Psychostimulants, such as ecstasy, are the most widely consumed illegal drugs among adolescents and young adults. AIMS:To describe and to analyse the different variables that can in...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2017-11-16 00:00:00
abstract:OBJECTIVE:To standardize and to determine the structural validity of a conduct disorder self report questionnaire in adolescents. PATIENTS AND METHODS:One hundred ninety, 12 to 16 year old male participants from the different socioeconomic status were randomized selected from educational institutions of Medellin City,...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-06-16 00:00:00
abstract:OBJECTIVE:To present the first Spanish case, perhaps the first non-Canadian, with ataxia type Charlevoix-Saguenay. CLINICAL CASE:A patient with important psychomotor delay and non-progressive ataxia has been studied in our Service during the first years of life and his follow-up has been carried out until 30 years of ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract:INTRODUCTION:Episodes of recurrent bacterial meningitis can occur in patients due to either congenital or acquired disorders. Congenital deformity of the bony labyrinth can be linked to a fistulous tract communicating it with the intracranial subarachnoid space. Mondini deformity is a frequent malformation in congenita...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-11-16 00:00:00