[Management of autonomic dysfunction in Parkinson's disease].

Abstract:

:Autonomic dysfunction is a common manifestation in patients with in Parkinson's disease, which can sometimes precede motor impairment. It can be expressed as orthostatic and postprandial hypotension, supine hypertension, hypersalivation, constipation, delayed gastric emptying, dyshidrosis, bladder and sexual dysfunction. It impairs the quality of life of patients and complicates the management of motor symptoms. Evidence available to treat complications is low. Our aim is to review the pathophysiology and clinical features of autonomic dysfunction in Parkinson's disease and provide a practical approach to handling the available evidence. TITLE:Manejo de la disfuncion autonomica en la enfermedad de Parkinson. :Resumen. La disfuncion autonomica es una manifestacion frecuente en los pacientes con enfermedad de Parkinson, que, en ocasiones, puede preceder a la afectacion motora. Se manifiesta en forma de hipotension ortostatica y posprandial, hipertension supina, sialorrea, estrenimiento, retraso del vaciamiento gastrico, dishidrosis, disfuncion vesical y sexual. Repercute significativamente en la calidad de vida de los enfermos, complicando el manejo de los sintomas motores. La evidencia disponible para el tratamiento de la mayoria de las complicaciones es escasa. Nuestro objetivo es revisar las caracteristicas fisiopatologicas y clinicas de la disfuncion autonomica en la enfermedad de Parkinson y aportar un enfoque practico en su manejo segun la evidencia disponible.

journal_name

Rev Neurol

journal_title

Revista de neurologia

authors

Crespo-Burillo JA,Alarcia-Alejos R

subject

Has Abstract

pub_date

2015-04-16 00:00:00

pages

355-64

issue

8

eissn

0210-0010

issn

1576-6578

pii

rn2014341

journal_volume

60

pub_type

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