Abstract：
INTRODUCTION:Restless legs is an unpleasant sensation in the calves that occurs when the individual is sitting or laying down, with an irresistible urge to move the legs. It has been know as a cause of insomnia. We have been using various drugs with a variety of effectiveness. Levodopa is now considered the drug of choice but drug tolerance is likely to develop the risk of drug dependence. Recently, a new drug was developed by Smithkline Beecham called ropinirol which principal indication is the treatment of initial phase of Parkinson's disease. PATIENTS AND METHODS:Base on the idea of the efficacy de la levodopa in patients with restless legs we administered 0.25 mg of ropinirol at bedtime to 15 of our patients diagnosed with restless legs syndrome. None of them had received positive results using the classic treatments during more than five years since they had developed this syndrome. Before the treatment was begun, we discontinued any medications relating to this illness. RESULTS:Beneficial effects were observed after the first administration and has continued until this time, 12 months after the initial treatment. Efficacy was measure by using sleep questionnaires (Spiegel). With only a pill (0.25 mg) at the moment of laying down at bedtime reports a clear improvement in the symptoms, including reducing the periodic leg movements. CONCLUSION:That improvements continue without any secondary side effects and without appearing to have built up any tolerance for the medication. Further research is needed to investigate the long term efficacy and side effects of this new treatment, but at this moment is a valuable and satisfactory tool to treat restless legs syndromes.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Estivill E,de la Fuente Vsubject
Has Abstractpub_date
1999-05-16 00:00:00pages
962-3issue
10eissn
0210-0010issn
1576-6578journal_volume
28pub_type
临床试验,杂志文章abstract：INTRODUCTION:Valproic acid (VPA) is a useful antiepileptic drug for controlling different types of epilepsy. It has several side effects and is associated to increased body weight, as well as metabolic and endocrine disorders, including metabolic syndrome. AIM:To determine the prevalence of obesity and metabolic syndr...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：INTRODUCTION:Since the 1980s, in relation to the spread of AIDS, there has been an enormous increase in cryptococcosis, a mycotic disorder which usually affects the central nervous system (CNS). This disease is caused by Cryptococcus neoformans, a microorganism acquired by inhalation of bird excrement. This germ produc...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-05-16 00:00:00
abstract：INTRODUCTION:Attention deficit disorder with or without hyperactivity (ADHD) is characterised by the patients' inability to pay attention in non selective activities, hyperactivity that is difficult to inhibit, impulsiveness with failure to control their reactions and an unstable personality, which gives rise to diffic...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-03-16 00:00:00
abstract：INTRODUCTION:Stroke is a leading cause of mortality and disability. Policosanol has been effective in brain ischemia models. The aim of this study is to investigate whether policosanol, added to aspirin therapy within 30 days of stroke onset, is better than placebo + aspirine for the long-term recovery of non-cardioemb...
journal_title：Revista de neurologia
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2017-02-16 00:00:00
abstract：INTRODUCTION AND DEVELOPMENT:Studies with conventional magnetic resonance imaging (MRI) support the hypothesis that cognitive impairment in multiple sclerosis (MS) patients is related with the lesion burden. Patterns of frontal lobe cognitive decline were also found to be related with the corresponding regional lesion ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-06-16 00:00:00
abstract：INTRODUCTION AND AIMS:The dysexecutive questionnaire (DEX) has been used to study executive deficits in both clinical samples (both psychiatric and neurological) and non-clinical samples, although agreement on its factorial structure is lacking. The aim of this research is to study that structure in the self-administer...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:Stroke is a recognized cause of disability among adults. However the impact that the deficits that occur after a moderate/severe stroke have on long-term disability, as well as the response of the resultant deficits to rehabilitation, are not completely understood. PATIENTS AND METHODS:A total of 396 pati...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2017-05-01 00:00:00
abstract：INTRODUCTION:The research group from Willmes and colleagues is one of the most advanced research groups in cognitive neuroscience. The use and nature of the numeric magnitude representation constitutes one of the study objects of the mentioned research group. This mental representation provokes a great controversy amon...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2008-03-01 00:00:00
abstract：PATIENTS AND METHODS:Fifty patients diagnosed as having epileptic crises were given neuropsychological tests including the Wechsler Adult Intelligence Scale or WAIS, Luria's neuropsychological test and a quantitative EEG examination. Multivariate analysis was done of the following variables: presence or absence of inte...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：AIM:To contribute to the knowledge of the cognitive differences existent between right-handed and left-handed evaluating the cognitive outcome in a group of adults right-handed and another group of left-handed of similar characteristic (age, gender, cultural level) by means of the Wechsler Adult Intelligence Scale (WAI...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2006-01-16 00:00:00
abstract：AIMS:The aim of this study was to determine whether the introduction of generic formulations of antiepileptic drugs (AED) would lead to an economic saving for the public health service. DEVELOPMENT:The narrow therapeutic index, low solubility and non-linear pharmacokinetics of some AED mean that the ranges of bioequiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
abstract：INTRODUCTION:Attention disorders are a major problem after traumatic brain injury underlying deficits in other cognitive functions and in everyday activities, hindering the rehabilitation process and the possibility of return to work. Functional neuroimaging and neuropsychological assessment have depicted theoretical m...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-03-01 00:00:00
abstract：:Few studies have been conducted on children and teenagers with borderline intelligence (BI) as a collective that shares this condition. In this paper we discuss the concept of intelligence and analyse the different cognitive profiles with which BI can be expressed. We also evaluate how aspects linked to a 'g' factor o...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-02-01 00:00:00
abstract：INTRODUCTION:In neuropathic pain, as occurs in epilepsy, researchers are striving to find a drug capable of inhibiting the pain-generating ectopic discharges that are produced as a result of neuronal hyperexcitability. This is mediated by ionic exchanges across the channels of the synaptic membrane. This is why the dru...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-10-01 00:00:00
abstract：INTRODUCTION:Chronic daily headache (CDH) includes primary headaches that last more than four hours with a frequency equal or superior to 15 days a month over the last three months. It has a prevalence of 4-5% in the general population and is a frequent reason for visiting the physician in headache units. AIM:To evalu...
journal_title：Revista de neurologia
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-10-16 00:00:00
abstract：INTRODUCTION:Cerebral infarction (CI) can be classified aetiologically in several different ways using explicit diagnostic criteria. However, the extent to which these diagnostic criteria are actually implemented in clinical practice is unknown. Aims. The aim of this study was to analyse the management and use of diagn...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：INTRODUCTION:Diabetes and dementia are growing problems throughout the world and especially in developing countries. AIM:To determine the risk of developing dementia in subjects with type 2 diabetes mellitus. PATIENTS AND METHODS:Diabetic elders free of dementia from the Mexican Health and Aging study, a prospective ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-10-01 00:00:00
abstract：AIM:To evaluate the performance of patients with Alzheimer's disease (AD) in the mild-moderate stage in a verbal material abstraction task that involves interpreting the implicit meaning of proverbs and sayings. SUBJECTS AND METHODS:A qualitative-quantitative analysis was carried out of the performance of 30 patients ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2009-12-01 00:00:00
abstract：INTRODUCTION:Congenital hydrocephalus or ventriculomegaly is a disorder that now can be diagnosed in uterus with ultrasonography, this gives the chance of being able to give a treatment the earliest as possible. DEVELOPMENT:The clinical manifestations are reviewed, the diagnosis, the frequent treatment and causes of c...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-10 00:00:00
abstract：TITLE:GNAO1: un nuevo gen a considerar en la distonia temprana de la infancia. : ...
journal_title：Revista de neurologia
pub_type： 信件,评审
doi：
更新日期：2018-05-01 00:00:00
abstract：AIM:To know the neural processes linked to the activity of brain circuits in order to understand the consequences of their dysfunction and their role in the development of neurodevelopmental diseases, such as autistic spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD). DEVELOPMENT:The activit...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-03-01 00:00:00
abstract：:Asymptomatic carotid stenosis is a relatively frequent pathology, although when considering the possibility of managing it surgically, there is still an important amount of disagreement concerning the criteria to be taken into account. This study conducts a broad examination of the condition, from its concept and epid...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2012-09-01 00:00:00
abstract：CASE REPORT:We report the case of an infant with septo-optic dysplasia, or Morsier's syndrome, which is a condition affecting the central nervous system that can only be confirmed by means of neuroimaging. This syndrome involves hypoplasia of one or both optic nerves, absence of septum pellucidum, agenesis of the corpu...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：TITLE:XXXI Reunion da Sociedade Galega de Neuroloxia. Comunicaciones. : ...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：2017-07-16 00:00:00
abstract：TITLE:Hemorragia vitrea bilateral asociada a hemorragia pontomesencefalica: un caso extremo de sindrome de Terson. : ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-07-15 00:00:00
abstract：INTRODUCTION:The reproductive functions of epileptic females often display alterations. This dysfunction can be due to psychological, physiological or pharmacological factors. These women have been described as having, for example, a higher incidence of anovulatory cycles, infertility, alterations affecting the hypotha...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-16 00:00:00
abstract：INTRODUCTION AND METHOD:The issue regarding the relations between behaviour and the brain is no longer the specific goal of neuropsychology, but rather that of the coordinated multidisciplinary activity of all the disciplines that go to make up the neurosciences. The specific contribution of neuropsychology to this mul...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:A number of studies suggest the existence of 'oxidative stress' in the substantia nigra from parkinsonian patients. If 'oxidative stress' should be relevant in the pathogenesis of Parkinson's disease (PD), the consumption of antioxidant or prooxidant substances in the diet could theoretically influence the ri...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-16 00:00:00
abstract：AIM:To determine if women with multiple sclerosis (MS) reported an increased risk of breast cancer compared with the general female population. PATIENTS AND METHODS:We conducted a systematic review and meta-analysis of observational cohort studies. We performed a search in PubMed/Medline of studies where standardized ...
journal_title：Revista de neurologia
pub_type： 杂志文章,meta分析,评审
doi：
更新日期：2010-11-01 00:00:00
abstract：INTRODUCTION:In recent years the demand for ambulatory neurological care has risen. Studying this situation can help to improve health care planning and the quality of the referrals from primary care. AIM:To analyse a number of variables involved in the first visits referred from primary care to neurology services. P...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
