Abstract：
INTRODUCTION:Alpha interferons (IFN a) have been shown to be effective in patients with chronic active hepatitis C. IFN a treatment may be associated with neurologic complications, including peripheral neuropathy. CASE REPORT:We describe a patient with active hepatitis C treated with IFN a, who developed peripheral neuropathy after a second cicle of treatment with interferon. He received a first cicle of treatment with IFN a during 22 weeks (6 MU/day 3 times a week). Afther that he did not received treatment during one year and then he received the second cycle (6 MU/day 3 times a week). After 3 months of therapy the patient complained about paresthesias of both legs. CONCLUSIONS:IFN a related neuropathy is probably rare; however, some cases may be misdiagnosed. Diagnosis of IFN a related neuropathy should be considered by physicians, particularly in patients given longterm treatment and high IFN a dosage. In this case we think that the patient had an acumulative efectt of interferon though he did not received treatment with interferon during one year.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Téllez-Zenteno JF,Negrete-Pulido O,Nuñez M,Estañol-Vidal B,García-Ramos Gsubject
Has Abstractpub_date
2002-10-01 00:00:00pages
644-6issue
7eissn
0210-0010issn
1576-6578pii
rn2001019journal_volume
35pub_type
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