Abstract:
AIMS:Our objective was to study the quality of life (QoL) in a sample of patients with multiple sclerosis (MS) as measured by their scores on the QoL questionnaire SF-36 (Short Form 36 Health Survey) and its relationship with the extent of deterioration of the disease according to the EDSS (Expanded Disability Status Scale). PATIENTS AND METHODS:The QoL SF-36 scale was administered to 78 patients with defined MS. Those who had suffered outbreaks or whose condition had clearly deteriorated in the past 6 months were excluded, and variables such as age, sex and gait disorders, among others, were analysed. Patients were divided into three groups according to their degree of disability on the EDSS scale: group 1 (EDSS 0-3), group 2 (EDSS 3.5-5.5) and group 3 (EDSS > 6). RESULTS:There were significant differences in the mean scores of groups 1 and 3 in several dimensions of the QoL questionnaire (p < 0.05): general state of health, emotional role, physical functioning, physical role and body pain. Differences were also observed in physical functioning and physical role in groups 1 and 2. In group 1, the dimensions with the lowest mean score were body pain and vitality. In group 3, the dimension with the lowest score was physical functioning. The health dimensions belonging to the realm of mental health were the ones that reflected the smallest difference according to the stage, since no statistical significance existed for dimensions such as vitality, social functioning or mental health. Body pain and vitality were more affected at an early stage (group 1) and the effects on physical functioning were stronger at a later stage (group 3). CONCLUSIONS:As the disease progresses (EDSS > 6), the dimensions of the QoL SF-36 questionnaire concerning physical health (physical functioning) become affected. Body pain and vitality are the most strongly affected dimensions in the early stages of the disease. These findings should be confirmed in a larger sample in order to provide them with a higher degree of validity.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Delgado-Mendilívar JM,Cadenas-Díaz JC,Fernández-Torrico JM,Navarro-Mascarell G,Izquierdo Gsubject
Has Abstractpub_date
2005-09-01 00:00:00pages
257-62issue
5eissn
0210-0010issn
1576-6578pii
rn2004504journal_volume
41pub_type
杂志文章abstract:INTRODUCTION:Diabetes and dementia are growing problems throughout the world and especially in developing countries. AIM:To determine the risk of developing dementia in subjects with type 2 diabetes mellitus. PATIENTS AND METHODS:Diabetic elders free of dementia from the Mexican Health and Aging study, a prospective ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION:The cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations of the Notch3 gene in the chromosome 19p13.1. and is characterized by small-vessel disease of the cerebral. The clinical feature consists of migraine, recurrent strokes, mood chan...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-11-16 00:00:00
abstract:INTRODUCTION:'Sword stroke' linear scleroderma, which is better known as linear scleroderma en coup de sabre (LSCS), is a rare disease with an uncertain causation that is characterised by progressive craniofacial focal atrophy and is, at least in part, different from Parry-Romberg syndrome (PRS). CASE REPORTS:Here, we...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract:INTRODUCTION:Parkinson's disease (PD) is a common neurodegenerative disease which begins in adulthood. Its incidence in Mexico is estimated to be 40-50 cases per 100,000 inhabitants/year and is the fourth reason for medical care in the National Institute of Neurology and Neurosurgery. The protein alpha-synuclein, SNCA,...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-10-16 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:The hereditary ataxias form a large, complex group of entities whose recognition is essential for correct genetic assessment, satisfactory clinical control and in some cases a suitable therapeutic approach. The clinico-semiological variety and advances in molecular biology have made the hered...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-01 00:00:00
abstract:INTRODUCTION:Virtual reality allows the user to interact with elements within a simulated scene. In recent times we have been witness to the introduction of virtual reality-based devices as one of the most significant novelties in neurorehabilitation. AIM:To review the clinical applications of the developments based o...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-10-16 00:00:00
abstract:AIMS:To appraise the attention deficit hyperactivity disorder assessment scale for a teenage population, EDAH (a). SUBJECTS AND METHODS:From an initial sample of 3400 participants, a final sample of 2292 pupils between 12 and 16 years of age were finally selected. Of the total number, 1066 were boys (46.5%) and 1226 w...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2010-09-16 00:00:00
abstract:INTRODUCTION:Brain creatine deficiencies are a group of inborn errors of metabolism recently recognized which are caused by arginine: glycine amidinotransferase (AGAT) deficiency, guanidinoacetate metiltransferase (GAMT) deficiency and defects in creatine transporter (CRTR). Although all of them are characterized by a ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-03-16 00:00:00
abstract:INTRODUCTION:Cavernous angiomas are angiographically occult vascular malformations that are present in 0.4% of people, and represent 5 13% of all cerebrovascular malformations. They can be alone or multiple, and sporadic or familial. The presence of multiple lesions is more frequent in familial cavernomatosis. OBJECTI...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:To obtain better understanding of the neurophysiology of sleep and of depression, together with any relationship there might be between them. DEVELOPMENT:We review the mechanisms of action of the neurotransmitters involved in the sleep-waking cycle, and also the antidepressive drugs, concentrating on those ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-16 00:00:00
abstract:INTRODUCTION:Both the moment and the way chosen to break the news that a child aged 0-6 years is suffering, or may suffer, from a developmental disorder or disability have an effect on the parents and on the familial system that goes beyond the actual fact of knowing about the circumstance in itself. It is a very signi...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2012-02-29 00:00:00
abstract:INTRODUCTION:Hirayama disease is a rare children's muscular atrophy that affects young Asian males, with muscular atrophy usually in one of the upper limbs that progresses slowly and later stabilises. It is diagnosed by means of electromyographic/electroneurographic with conduction speed studies (EMG/ENG-CS) and by mag...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Surgical treatment for thoracolumbar union instability represents a challenge, due to the difficult access to this area of the spine, and to the extreme variability of morphological and biomechanical lesions observed. AIM:To describe the indications and clinical and neuroradiological results obtained with...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:To study the role of the serotonin transporter gene (SLC6A4) in the emotional processing of auditory hallucinations can be particularly important to better understand the pathophysiology of auditory hallucinations. Moreover, a poly-morphism located in this gene (5-HTTLPR) has been previously associated wit...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2010-03-16 00:00:00
abstract:TITLE:Uso compasivo de cannabidiol en espray para el tratamiento de paraparesia espastica en un paciente con adrenomieloneuropatia. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION:Although visual symptoms of multiple sclerosis (MS) are very frequent, they are rarely related with treatment with interferon. This is the first case reported in the literature of retinopathy associated with subcutaneous interferon beta-1a, and the second related to interferons in MS. CASE REPORT:A 30-yea...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-04-16 00:00:00
abstract::Although infrequent, one of the etiological causes of aseptic meningoencephalitis is drug-induced. In our patient, two cases of meningocephalitis took place over a period of six years, together with a meningismus following consumption of trimetroprim-sulphametoxazol (cotrimoxazol). Features of the cases were mental co...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::We present the association of a distrophinopathy with a case of facioscupulohumeral dystrophy in two individuals belonging to the same family. The discrepancy in the seric creatinphosphokinase (CPK) of the two patients together with certain clinical data suggests the possibility that it is a question of two different ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:INTRODUCTION:Progressive cerebral polidystrophy or Alpers syndrome is a clinico-pathological picture, with no specific biological marker, characterized by involvement mainly of the cerebral grey matter and which shows clinically as a rapidly progressive encephalopathy with intractable seizures, usually myoclonic. The t...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:Disorders of movement in children frequently cause difficulties with both the semiology and the diagnostic approach. DEVELOPMENT:Based on our experience, we analyze useful strategies to overcome these difficulties and consider the clinical semiology, use of complementary tests and therapeutic approach. CONC...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-08-16 00:00:00
abstract:INTRODUCTION:In epidemiological investigation valid, reliable means of diagnosing the illnesses studies are essential. OBJECTIVE:To validate the self-questionnaire 'Alcoi 1995' for the diagnosis of migraine. METHODS:We used the questionnaire Alcoi-1992 (which had been validated previously) to find the prevalence of m...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-08-01 00:00:00
abstract:INTRODUCTION:The development of scientific advances, constantly opening new frontiers of knowledge, leads to increasing complexity and specialization. DEVELOPMENT:The conflict between the never ending medical specialization and the opposite tendency, which is based mostly on economic grounds, prevents the acquisition ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVES:To review current knowledge regarding the mechanisms of action, pharmacokinetics, clinical efficacy and the tolerance of topirimate (TPM) and describe the Spanish experience of the use of this drug in 224 patients of all ages. DEVELOPMENT:TPM is a new drug which affects practically all the mechanisms involv...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-06-01 00:00:00
abstract::INTRODUCTION. A large number of neurological diseases course with impairment of higher cognitive functions, their evaluation being important for diagnostic, prognostic and therapeutic purposes. The main purpose of neuropsychological assessment is to identify behavioral, emotional and cognitive consequences of brain dy...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2014-12-16 00:00:00
abstract:INTRODUCTION:Neurocysticercosis is the most frequent parasitic disease affecting the central nervous system. It is a disease that is endemic to certain countries in South America. The phenomenon of immigration, however, has increased its prevalence in developed regions due to the arrival of immigrants from endemic area...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-02-16 00:00:00
abstract:INTRODUCTION:Human beings are characterised by the specialisation of certain functions, such as language or the ability to walk. We have achieved this capacity thanks to the development of multiple connections among different areas of the central and peripheral nervous system, together with adaptation of the musculoske...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-23 00:00:00
abstract:AIMS:To review the fundamentals of occupational therapy (OT) and to present its possible contributions in the field of neurological rehabilitation. DEVELOPMENT:As its name suggests, OT is a form of treatment that makes use of occupations. Furthermore, occupation is a purpose itself, since OT seeks to adapt the individ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-08-16 00:00:00
abstract::Different therapeutic models have been presented with which to treat the condition of attention deficit hyperactivity disorder (ADHD) and the scientific literature speaks of the benefits linked to multimodal approaches. The National Institute of Mental Health report grants combined treatments an essential role. Throug...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract:INTRODUCTION:Tourette syndrome is a neurologic disorder characterized by involuntary vocal and motor tics. It affects around 1 to 2% of school-age children and is the most common movement disorder in paediatric age. Tics are involuntary or semivoluntary, sudden, brief, intermittent, repetitive movements (motor tics) or...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-23 00:00:00
abstract:UNLABELLED:Introduction. Epileptic crises presenting exclusively during sleep are rare and pose more problems of diagnosis than do crises of diurnal presentation. PATIENTS:We present the clinical and electroencephalographic data of 20 patients with exclusively sleep-induced epileptic crises, evaluating not only the ty...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00