Abstract:
AIM:To identify the clinical and psychosocial factors of a Colombian cohort of patients with juvenile myoclonic epilepsy and its relation to crisis control. PATIENTS AND METHODS:Retrospective cohort study of patients over 14 years of age with a diagnosis of juvenile myoclonic epilepsy, with 12 months of follow-up in an epilepsy program, where the sociodemographic and clinical characteristics and the survey for the assessment of relapse conditioners. A bivariate and multivariate analysis was performed using binary logistic regression. RESULTS:Clinical records between November 2014 and December 2016 where 145 patients with a diagnosis of juvenile myoclonic epilepsy who met the selection criteria were evaluated. The factors associated with crisis control were: health plan, accessibility, personal attitudes, history of consumption, drug resistance, and crisis number per month; of these, health plans, personal attitudes, and crisis number per month persist with statistical significance after the logistic regression analysis. CONCLUSION:Psychosocial factors not only impact on crisis control, added to clinical factors explain 40% of crisis control in patients with juvenile myoclonic epilepsy and therefore affect their long-term prognosis. TITLE:Factores clínicos y psicosociales asociados al control de crisis en pacientes con epilepsia mioclónica juvenil. :Objetivo. Identificar los factores clínicos y psicosociales de una cohorte colombiana de pacientes con epilepsia mioclónica juvenil y su relación con el control de las crisis. Pacientes y métodos. Estudio de cohortes retrospectivo de pacientes mayores de 14 años con diagnóstico de epilepsia mioclónica juvenil, con 12 meses de seguimiento en un programa de epilepsia, donde se evaluaron las características sociodemográficas y clínicas y la encuesta para la valoración de los condicionantes de recaída. Se realizó un análisis bivariado y multivariado mediante regresión logística binaria. Resultados. Registros de historias clínicas entre noviembre de 2014 y diciembre de 2016, donde se evaluó a 145 pacientes con diagnóstico de epilepsia mioclónica juvenil que cumplieron los criterios de selección. Los factores asociados al control de las crisis fueron: plan de salud, accesibilidad, actitudes personales, antecedente de consumo, farmacorresistencia y número mensual de crisis; de éstos, plan de salud, actitudes personales y número mensual de crisis persisten con significación estadística tras el análisis de regresión logística. Conclusión. Los factores psicosociales no sólo influyen en el control de las crisis sino que, sumados con algunos factores clínicos, podrían explicar el 40% del control de las crisis en los pacientes con epilepsia mioclónica juvenil y, por ende, influir en su pronóstico a largo plazo.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Sánchez-Zapata P,Zapata-Berruecos JFdoi
10.33588/rn.6911.2019305subject
Has Abstractpub_date
2019-12-01 00:00:00pages
453-460issue
11eissn
0210-0010issn
1576-6578pii
rn2019305journal_volume
69pub_type
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