Abstract:
INTRODUCTION:Attention deficit disorder with or without hyperactivity (ADHD) is characterised by the patients' inability to pay attention in non selective activities, hyperactivity that is difficult to inhibit, impulsiveness with failure to control their reactions and an unstable personality, which gives rise to difficulties in learning, work, leisure activities and in the social milieu, and may get worse in unstructured settings. There is a clear predominance in males and a 57% possibility of inheritance. The biochemical causes underlying ADHD are unknown, although it is currently accepted that dopamine and noradrenaline release is reduced because of the positive response to methylphenidate (MPH) and other stimulants. AIMS:The aim of this study was to evaluate the response to immediate release MPH by combining clinical data based on the DSM IV and brain mapping and quantitative electroencephalogram studies (qEEG). PATIENTS AND METHODS:We conducted a study of 170 otherwise pathology free children with a 5 to 1 predominance of males and an average age of 8 years old. Patients' records were examined and a hemogram and general biochemical analysis were carried out together with tests to determine thyroid hormone and cortisol levels, and BM CEEG. In addition, 46 children were submitted to a nocturnal polysomnogram (nPSG). RESULTS:A third of the children presented associated pathologies such as allergic rhinitis, asthma, allergies and dermatitis, with no differences between sexes. Paroxysmal discharges were revealed by the nPSG in 16.7% and there was a general agreement between answers provided by families and teachers. In the qEEG the most striking data was the theta/alpha quotient, which showed a medium degree of generalised dominance of the theta band (but no correlation with age) in 49.9% and it was mild in 5.9%. Following a year's treatment, there was an overall, not focal, improvement in activity, mild dominance rose to 58.2% and the others fell 2.4%. The other traces were unspecific. Clinical progression was good in 78.2% of cases, 19.5% of mild complications being resolved by lowering the drug dosage or by withdrawing it altogether. CONCLUSIONS:1). ADHD is more likely to remain into adulthood and it has been associated to immunological disorders or epileptiform paroxysms, although only in a minority of cases. 2). The effect of MPH can be objectified by serial recordings of digitised cortical bioelectrical activity, with synchronised progression of the clinical response.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Valdizán JRsubject
Has Abstractpub_date
2004-03-16 00:00:00pages
501-6issue
6eissn
0210-0010issn
1576-6578pii
rn2004067journal_volume
38pub_type
杂志文章abstract::The established risk factors for ischemic stroke do not sufficiently explain all clinical and epidemiological features of the disease, such as the winter peak of stroke incidence, the decline of stroke during this century and the time point of cerebral ischemia. A role of infectious disease as stroke risk factor may p...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1999-11-01 00:00:00
abstract::Alcohol intake is facilitated by its relationship with eating behavior and both processes are highly influenced by situations of stress and anxiety. The dysregulation of these processes can reach pathological situations such as anorexia, bulimia or obesity. The neurobiological elements which underlie this control are ...
journal_title:Revista de neurologia
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更新日期:2018-09-01 00:00:00
abstract:INTRODUCTION:Hypertrophic pachymeningitis is an infrequent disease that is characterised by inflammatory hypertrophy of the dura mater. There are cranial, spinal and craniospinal forms of the disease. They may be due to underlying infectious, autoimmune or neoplastic processes, although most of the cases reported in re...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2006-10-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
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更新日期:2004-08-16 00:00:00
abstract:INTRODUCTION:Progressive cerebral polidystrophy or Alpers syndrome is a clinico-pathological picture, with no specific biological marker, characterized by involvement mainly of the cerebral grey matter and which shows clinically as a rapidly progressive encephalopathy with intractable seizures, usually myoclonic. The t...
journal_title:Revista de neurologia
pub_type: 杂志文章
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更新日期:2000-12-01 00:00:00
abstract::Epilepsy is a neurological disorder that affects 1-2% of the population. Despite the available treatments (drug therapy, resective surgery, vagus nerve stimulation), there is a significant subgroup of patients that continues to have disabling seizures. The indications of deep brain stimulation are exponentially growin...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-07-16 00:00:00
abstract:INTRODUCTION:Attention disorders are a major problem after traumatic brain injury underlying deficits in other cognitive functions and in everyday activities, hindering the rehabilitation process and the possibility of return to work. Functional neuroimaging and neuropsychological assessment have depicted theoretical m...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-03-01 00:00:00
abstract::In recent years there has been a striking increase in the number of transnational adoptions in our country, which follows the trend already observed in other developed European countries. Major contributing factors to this phenomenon have been the improvements in socioeconomic conditions in our country, the drop in th...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2003-02-01 00:00:00
abstract:INTRODUCTION:Thymectomy is a surgical procedure which is generally accepted for treatment of myasthenia gravis. OBJECTIVE:To describe the long-term evolution of 217 myasthenic patients who had had thymectomies in the Hospital Clinico Quirurgico Hermanos Ameijeiras in La Habana, Cuba. PATIENTS AND METHODS:We determine...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract:INTRODUCTION:Cerebrovascular accidents (CVA) are the third most common cause of death and are the main cause of permanent disability in the western world, where they also rank first as regards the loss of years of disability-adapted independent life. Ischaemic CVAs tend to present irreversible sequelae, which reduces t...
journal_title:Revista de neurologia
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2007-11-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-08-16 00:00:00
abstract:INTRODUCTION:Diverse evidences have shown that the process of natural aging causes a decline in different cognitive functions, including among them the attentional process. AIM:To determine how the healthy aging affects to the different attentional networks. SUBJECTS AND METHODS:Two groups: young subjects (32.5 ± 9.7...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:Some medical factors related with cardiopulmonary resuscitation (CPR) outcome are known. Moreover, there are other factors, not strictly medical ones, as age, gender, race and socioeconomic status, that influence on decisions of CPR. The aim of this study was to analyse the influence of all t...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract:INTRODUCTION:5% of patients with sarcoidosis are affected by neurological complications, of which myopathy is one of the least frequent. We report the clinical course and therapeutic response of two patients with sarcoid myopathy. CASE REPORTS:We observed two females aged 63 and 55 who were previously diagnosed with s...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-08-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2003-03-01 00:00:00
abstract:INTRODUCTION:Stroke is a leading cause of mortality and disability. Policosanol has been effective in brain ischemia models. The aim of this study is to investigate whether policosanol, added to aspirin therapy within 30 days of stroke onset, is better than placebo + aspirine for the long-term recovery of non-cardioemb...
journal_title:Revista de neurologia
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2017-02-16 00:00:00
abstract:INTRODUCTION:In the last decades psychological studies have demonstrated the effectiveness of the cognitive-behavioural therapy for most anxiety and depressive disorders. Recently, a different and complementary approach in terms of validation of cognitive-behavioural therapy has emerged: testing the efficacy of these t...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION:Visual phenomena can be symptoms of epileptic seizures, although with an uncertain clinical meaning and relationship with the epileptogenic focus. AIMS:To describe the clinical implications of visual epileptic seizures according to their signs and symptoms in adults. PATIENTS AND METHODS:Data were collec...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2015-03-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:The neurological concept of learning is approached from a cybernetic point of view, taking into account that a child should recognize a fact, learn it semantically and decided whether it is worth storing; the dynamic aspect of memory is the true motor of the ability to learn and all this is modulated by th...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract:INTRODUCTION:Benign idiopathic external hydrocephalus (BIEH) is an age-dependent disorder that is self-limiting in time and has an uncertain aetiology. PATIENTS AND METHODS:A retrospective study was conducted involving 39 patients (16 girls and 23 boys) with BIEH. The following data were analysed for each patient: age...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract::Streptococcus pyogenes (or group A beta hemolytic streptococcus) is a pathogenic bacterium that can give rise to a range of invasive and autoimmune diseases, although it is more widely known as the cause of tonsillitis. It is particularly interesting to note that this germ only causes disease in humans. For many years...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2003-07-01 00:00:00
abstract:INTRODUCTION:The occupational environment generates a large amount of illness which involves several specialities, including neurology. However, there is little awareness--or little training--in this field as in most medical specialities, since in the basic tool of a doctor's work, the clinical history, importance is s...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:AIM:To determine if women with multiple sclerosis (MS) reported an increased risk of breast cancer compared with the general female population. PATIENTS AND METHODS:We conducted a systematic review and meta-analysis of observational cohort studies. We performed a search in PubMed/Medline of studies where standardized ...
journal_title:Revista de neurologia
pub_type: 杂志文章,meta分析,评审
doi:
更新日期:2010-11-01 00:00:00
abstract::Two patients aged 52 and 31 respectively, treated for male infertility with gonadotrophins (LCG/LMG), showed marked improvement of their migraine crises associated with a typical aura which had been present since puberty. Changes in the number, motility and morphology of the spermatozoids were seen in the seminogram. ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::We report a 25-year-old woman with gradual loss of visual acuteness, during puerperium and blindness in fifteen days. Two months latter she remain steady. Visual evoked potentials using monocular checkerboard pattern-reversal, were abnormal. Clinical suspicion of voluntary alteration of VEP was considered. A second VE...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION:The epidemiology of multiple sclerosis (ME) in the Alcoi area has been studied by our groups for many years. When studying the factors linked to ME in this area initially we observed that migration, contact with dogs and the textile industry were associated with the disorder. A later study, in which the mi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00