Abstract:
INTRODUCTION:The ganglioside GM1 has been shown to be effective in the treatment of experimental cerebral ischemia. Gangliosides from bovine brain have not been used in the treatment of ischemic cerebral accidents. There is evidence suggesting that they may also be effective. RESULTS:Ten minutes of bilateral occlusion of the carotid arteries of Mongolian gerbils leads a week later to reduced spontaneous exploratory activity, assessed by counting the number of times they stood up in an open field over a period of three minutes, and retarded neuronal death in the pyramidal stratum of the CA1 sector of the hippocampus, evaluated on the density of normal neurons in this region of both hemispheres. Treatment with 30 mg/kg of intra-peritoneal bovine cerebral gangliosides during the first six days following occlusion of the carotid arteries, leads to conservation of both exploratory activity and density of pyramidal neurons observed in the control animals. CONCLUSIONS:Bovine cerebral gangliosides have a short term cytoprotector effect on neurons sensitive to the ischemia-reperfusion phenomenon. This effect may be due to more than one mechanism, in which other gangliosides (together with GM1) may be present due to transient permeability of the blood-brain barrier.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
García-Salman JD,Córdoba-Ramos M,Cuba-Peña Asubject
Has Abstractpub_date
1998-10-01 00:00:00pages
585-8issue
158eissn
0210-0010issn
1576-6578journal_volume
27pub_type
杂志文章abstract:OBJECTIVE:To evaluate, using transcranial Doppler, changes in parameters in patients with cerebral hematoma, as compared with controls, for detection of possible regional hypoperfusion. PATIENTS AND METHODS:We studied 24 patients with cerebral hematomas and 15 healthy volunteers. The volume of the hematoma and the hyp...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-07-16 00:00:00
abstract:INTRODUCTION:Both the normal and pathological development and involution of the CNS are regulated by an important set of both, 'growth factors' (inducing growth, differentiation, survival, adaptation or plasticity in neurons) and 'ageing factors' (inducing involution, atrophy, necrosis or apoptosis). In neurodegenerati...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1997-10-01 00:00:00
abstract:INTRODUCTION:The combination of subarachnoid hemorrhage (SAH) and subhyaloid hemorrhage is known as 'Terson syndrome'. Retinal hemorrhage is commonly observed clinically in the optic fundi of patients with SAH, however, subhyaloid hemorrhage of the globe in the setting of SAH has been rarely on CT of the brain. Several...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:INTRODUCTION:Arachnoid cysts are cavities with a content similar to cerebrospinal fluid, frequently communicating with the subarachnoid space. They make up 1% of the intracranial space occupying lesions, and although typically seen in children (13%), they may be undiagnosed until the patient has become adult. PATIENTS...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-08-16 00:00:00
abstract:INTRODUCTION:Cerebrotendinous xanthomatosis is an inherited autosomal recessive lipid storage disease. Clinical features include tendon xanthomas, premature cataracts and progressive neurologic dysfunctions. Substantial elevation of serum cholestanol and urinary bile alcohols and their precursors establishes the diagno...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:INTRODUCTION:Surgery for resection of supratentorial lesions near the motor areas and/or internal capsule carries an associated risk of damage to cortical or subcortical motor pathways. Intraoperative brain mapping, using direct cortical electric stimulation, is a surgical adjunct used during lesionectomy in functional...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2009-06-16 00:00:00
abstract::Different therapeutic models have been presented with which to treat the condition of attention deficit hyperactivity disorder (ADHD) and the scientific literature speaks of the benefits linked to multimodal approaches. The National Institute of Mental Health report grants combined treatments an essential role. Throug...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract:INTRODUCTION:Scientific cooperation is essential for the advance of science. Bibliometrics and social network analysis offer evaluation indicators to analyse collaboration in scientific papers. The aim of this study is to characterize scientific collaboration patterns in Revista de Neurología between 2002 and 2006. MA...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract:INTRODUCTION:Protein-energy malnutrition continues to affect millions of human beings in developing countries. Children suffer most from the shortage of nutrients because at early ages malnutrition has an important impact on the central nervous system. The changes that malnutrition triggers in the brains of these child...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-03-02 00:00:00
abstract:INTRODUCTION:Diverse evidences have shown that the process of natural aging causes a decline in different cognitive functions, including among them the attentional process. AIM:To determine how the healthy aging affects to the different attentional networks. SUBJECTS AND METHODS:Two groups: young subjects (32.5 ± 9.7...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Drug abuse is related to neurocognitive alterations linked to the functioning of several areas of the brain. The application of advanced neuroimaging techniques has allowed important advances to be made in research being conducted on why stable disorders are produced in the brain mechanisms responsible for...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-04-01 00:00:00
abstract:INTRODUCTION:The damage caused to the central nervous system by lightning can be immediate or delayed. Cerebrovascular accidents are usually an infrequent complication of lightning strikes. CASE REPORT:We report the case of a patient who was hit by lightning and then developed an acute bilateral intraparenchymatous ha...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-09-16 00:00:00
abstract:INTRODUCTION:Chronic daily headache (CDH) includes primary headaches that last more than four hours with a frequency equal or superior to 15 days a month over the last three months. It has a prevalence of 4-5% in the general population and is a frequent reason for visiting the physician in headache units. AIM:To evalu...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-10-16 00:00:00
abstract:OBJECTIVE:To review the incidence and causes of the infections and metabolic diseases of the nervous system in patients with systemic neoplasias. DEVELOPMENT:Patients with immunodeficiency, particularly those with hematological neoplasias and persons treated with immunosuppressive drugs have a considerable tendency to...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-12-16 00:00:00
abstract::INTRODUCTION. Scientific collaboration is vital for to the advance of knowledge and is especially important in health sciences. The aim of this study is to identify scientific collaboration indicators and co-authorship networks of researchers and Spanish institutions that publish on multiple sclerosis (MS) during the ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2013-08-16 00:00:00
abstract:INTRODUCTION:In this investigations, was carried out a neurocysticercosis (NC) prevalence study during seven months in the Instituto Neurológico de Antioquia with the purpose of known neurocysticercosis frequency as cause of epilepsy in patients older than ten years that we attended in our institute. MATERIAL AND METH...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:INTRODUCTION:Fractures of the odontoid process make up between 10 and 15% of all cervical fractures. The decision as to when to operate on them is still controversial; the dilemma as to whether to use surgical or conservative treatment is still a problem. PATIENTS AND METHODS:We designed a descriptive study, which was...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:INTRODUCTION:It is necessary to know the degree of concordance of preoperative studies in temporal lobe epilepsy (TLE). AIM. To analyze the relative importance of different preoperative tests (vEEG, EEG, SPECT and MRI), the degree of agreement between them, and to develop a Bayesian probability model for diagnosis. PA...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract::Several predispocitional and genetic factors are thought to be involved in the etiology of Alzheimer s disease (AD). Except for age, there is no consensus among researchers about the factors that can best predict AD. Some studies have found that, older women, cerebrovascular risk factors (hypertension, ischemic heart ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-07-16 00:00:00
abstract:INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-10-16 00:00:00
abstract:INTRODUCTION:The research group from Willmes and colleagues is one of the most advanced research groups in cognitive neuroscience. The use and nature of the numeric magnitude representation constitutes one of the study objects of the mentioned research group. This mental representation provokes a great controversy amon...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-03-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:Medulloblastoma is a cerebellar small cell tumor, whose ancestor cell has not been yet identified in the human normal embriology: its exact origin is, in fact, still unknown. Nevertheless, one of the most acceptable possibilities facing the origin of the tumor is the remaining rests of cere...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-08-16 00:00:00
abstract:INTRODUCTION:The efficiency of Cambridge Cognitive Examination' (CAMCOG) is analyzed as a tool to detect dementias in epidemiological studies. PATIENTS AND METHODS:The data were obtained from subjects who enrolled the second phase on a door-to-door field epidemiological study. The tool used was the 'Cambridge Mental D...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-16 00:00:00
abstract::Autism is a developmental disorder affecting social relationships, communication and flexibility of thought. These three basic aspects of autism may present in many different forms and degrees. Therefore autism should be considered to be a spectrum of autistic disorders rather than a single strictly defined condition....
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:Chronic migraine is the most frequent complication of migraine. It is defined by the presence of headache on 15 or more days a month, of which at least eight must meet the criteria of migraine without aura for a minimum of three months. In addition they must not be due to medication abuse or attributable t...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2012-05-16 00:00:00
abstract:INTRODUCTION:Charcot-Marie-Tooth disease (CMT) is a neuropathy that affects sensory and motor nerves. The most common CMT subtype is CMT1A due to a PMP22 duplication of a 1.5 Mb fragment on the 17p11.2-p12. The development of a specific molecular technique that detects the PMP22 duplication is necessary for the diagnos...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION:The developmental amnesia is a recently known entity that occurs as a consequence of hypoxic-ischemic events in the perinatal period. This is a specific deficit of episodic memory with greater preservation of semantic memory and other memory components such as the immediate and working memory. It occurs in...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:Decrease in incidence of neurosyphilis over the last few decades implies that clinicians consider less frequently this diagnosis. On the other hand, some reports suggest an increase in atypical forms of this disease that represent an additional reason for missing this diagnosis. CLINICAL CASE:We report on...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-09-16 00:00:00
abstract:INTRODUCTION:Purely bulbar hematomas are not common (0.25%-0.50% of all intraparenchymatous hematomas), probably because of the particular characteristics of the anatomy and hemodynamics of the bulbar circulation. CLINICAL CASES:We selected 18 cases. Three of these were our own and the purely bulbar localization was c...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
abstract:INTRODUCTION:It is known as segmental neurofibromatosis type 1 (NF1) a type of NF1 characterized by the features circumscribed to one or more body cutaneous and/or subcutaneous segments. This entity is recognized from recently and it is related with somatic mosaicism. PATIENTS AND METHODS:43 patients (29 females and 1...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-10-16 00:00:00