Abstract：
:Several predispocitional and genetic factors are thought to be involved in the etiology of Alzheimer s disease (AD). Except for age, there is no consensus among researchers about the factors that can best predict AD. Some studies have found that, older women, cerebrovascular risk factors (hypertension, ischemic heart disease, diabetes mellitus), and the presence of the apolipoprotein E (APOE) 4 allele to be associated with the development of dementia and AD. However, there are a few large scale studies that have entered magnetic resonance imaging (MRI) findings in the analysis of risk factors for AD. The Cardiovascular Health Study Cognition Study evaluated the determinants of the risk of dementia, diagnosed in 1998 99, among 3608 participants >65 years of age who had MRIof the brain in 1991 through 1994. In this cohort, there were 480 incident dementia cases, and 330 were diagnosed as AD. The CHS found that age, Modified Mini Mental State Examination scores, cerebral ventricular size, severity of white matter lesions, number of MRI identified infarcts, and the presence of the APOE 4 allele were predictors of dementia. This study showed the importance of controlling for neuroimaging findings the study of risk factors for dementia. Scores of global cognitive measures, the presence of the APOE 4 allele, and MRI of the brain were strong predictors of dementia and AD.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Kuller LHsubject
Has Abstractpub_date
2003-07-16 00:00:00pages
122-6issue
2eissn
0210-0010issn
1576-6578pii
rn2002445journal_volume
37pub_type
杂志文章abstract：INTRODUCTION:Charcot-Marie-Tooth disease (CMT) is a neuropathy that affects sensory and motor nerves. The most common CMT subtype is CMT1A due to a PMP22 duplication of a 1.5 Mb fragment on the 17p11.2-p12. The development of a specific molecular technique that detects the PMP22 duplication is necessary for the diagnos...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2014-08-01 00:00:00
abstract：AIM:To analyze the importance of the neurotransmitter glutamate in the pathogenesis of Alzheimer's disease (AD). DEVELOPMENT:Elements of the physiological glutamatergic neurotransmission are reviewed, such as the neuronal types that utilize it, glutamatergic receptors and their characteristics, and glutamate transport...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To review the incidence and causes of the infections and metabolic diseases of the nervous system in patients with systemic neoplasias. DEVELOPMENT:Patients with immunodeficiency, particularly those with hematological neoplasias and persons treated with immunosuppressive drugs have a considerable tendency to...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-16 00:00:00
abstract：INTRODUCTION:Epilepsy is a common disease with important social and economic repercussions. Patients with epilepsy have traditionally been discriminated by both the general population and physicians. A physician's lack of knowledge about epilepsy could be the cause of an incorrect clinical control (CC). AIMS:The purpo...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：INTRODUCTION:The theory of memory consolidation, based on the work published by Georg Elias Muller and Alfons Pilzecker over a century ago, continues to guide research into the neurobiology of memory, either directly or indirectly. In their classic monographic work, they concluded that fixing memory requires the passag...
journal_title：Revista de neurologia
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:The ischemic stroke represents a very important cause of death in the hospitals. The clinic changes of this disease and the frequent morphological evidence in necropses motived the study of the clinicopathological concordance taking as reference two institutions of the secondary attention. The two medical ce...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-11-16 00:00:00
abstract：INTRODUCTION:Oxidative stress increases brain lipid peroxidation, memory and motor deficits and progressive neurodegeneration. Tibolone, a treatment for menopausal symptoms, decreases lipid peroxidation levels and improves memory and learning. AIM:To study the effect of chronic administration of tibolone on lipid pero...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2014-05-16 00:00:00
abstract：INTRODUCTION:Cerebrovascular accidents (CVA) are the third most common cause of death and are the main cause of permanent disability in the western world, where they also rank first as regards the loss of years of disability-adapted independent life. Ischaemic CVAs tend to present irreversible sequelae, which reduces t...
journal_title：Revista de neurologia
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-11-01 00:00:00
abstract：INTRODUCTION:It may be difficult to determine the adequate mement, the information content and the most convenient person to inform patients with chronic, incurable disorders with uncertain prognosis as sclerosis multiple (MS). MATERIAL AND METHODS:To gain information on how these aspects had been carried-out and the ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Today, the fact that sensory integration difficulties with a neurological basis exist and that they seriously condition the development of those individuals who suffer from them is widely accepted and acknowledged as being obvious by the vast majority of professionals working in the field of community healthcare. Howe...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：2017-02-24 00:00:00
abstract：INTRODUCTION:Attention deficit hyperactivity disorder (ADHD) is a neurobiological condition essentially characterised by inattention, hyperactivity and impulsiveness, and has a prevalence of around 5%. Because it is a biological disorder, both boys and girls with ADHD display these same symptoms, but more boys are diag...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-03-02 00:00:00
abstract：INTRODUCTION:In the last years, the changes in glial cells during different alterations in the Central Nervous System have been studied. It is known that astrocytes and microglial cells are the glial cells which present the major reactivity. OBJECTIVE:The aim of this work was to analyze the glial cell changes induced ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:Parkinson's disease (PD) is characterized by motor symptoms such as bradykinesia, rigidity, alteration of postural reflexes and tremor at rest and other non-motor symptoms such as changes in sleep patterns and sexual behavior. However, little is known about paraphilic sexual behaviors. AIM:To summarize th...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-08-16 00:00:00
abstract：:The most relevant data presented at the 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), held in October 2013 in Denmark, were summarised at the sixth edition of the Post-ECTRIMS Expert Meeting held in Madrid in October 2013, resulting in this review, which is being p...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：2014-10-16 00:00:00
abstract：INTRODUCTION:Checkpoint inhibitors have dramatically transformed cancer treatment. However, due to the increasing number of tumors in which they are used, there is a high number of reported adverse effects. Among them, we highlight neurological side effects. In the approbatory clinical trials, they were thought to be s...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：10.33588/rn.6807.2019022
更新日期：2019-04-01 00:00:00
abstract：AIMS:Following the diagnosis of intellectual disability, a prognosis can be offered concerning the degree of autonomy the child will be able to achieve based on prior experience, but which depends on the aetiology of the disability. It is still difficult to give a prospective answer regarding the capacity to reach an o...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-01-15 00:00:00
abstract：INTRODUCTION:An important aim of neuropsychological assessment is to identify impairment in higher cognitive or intellectual, functioning. In order to achieve this task the assessment of premorbid intellectual ability becomes crucial. The estimation of premorbid cognitive functioning will allow us to assess level of co...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：AIM:To assess the budget impact of the treatment for relapsing remitting multiple sclerosis (RRMS), interferons, and glatiramer acetate, from the National Health System perspective in Spain. PATIENTS AND METHODS:A budget impact model was designed to compare the cost of RRMS treatment in different settings, using a fiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：:INTRODUCTION. Since James Parkinson published what can be considered the first treaty on the disease that bears his name in 1817, the scientific literature on this pathology has not ceased to grow. But the illness has also been represented in literature, the cinema and on television, where the symptoms, treatment and ...
journal_title：Revista de neurologia
pub_type： 历史文章,杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：INTRODUCTION:The possibility of diagnosing carotid stenosis and carrying out surgery without arteriography has increased with the use of different diagnostic methods. The eco-Doppler has been shown to be a useful method, although it requires previous individualised validation. OBJECTIVE:We aim to validate our Vascular...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:The Landau-Kleffner syndrome consists of the association of paroxysmal EEG abnormalities, more marked during sleep, acquired aphasia usually of receptive type, and epileptic seizures in three quarters of cases. Additional features include behavioral disturbances that may even present with autistic features, cognitive ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-08-16 00:00:00
abstract：INTRODUCTION:Episodes of recurrent bacterial meningitis can occur in patients due to either congenital or acquired disorders. Congenital deformity of the bony labyrinth can be linked to a fistulous tract communicating it with the intracranial subarachnoid space. Mondini deformity is a frequent malformation in congenita...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-11-16 00:00:00
abstract：INTRODUCTION:The diagnosis of attention deficit disorder with or without hyperactivity (ADHD) is a controversial process that may be conditioned to a certain extent by the system of diagnostic classification, by the measuring instrument, by the population that has been chosen for study and by the source of information....
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-11-16 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:Advances in genetics, techniques for diagnosis and treatment, and increasing concern for the quality of life and neuropsychological aspects of epileptic children and the possible repercussions of treatment lead to changes in the approach to epilepsy and require continual adaptation. In this ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-10-16 00:00:00
abstract：OBJECTIVES:To review current literature on population, cytogenetic and molecular studies of specific language disorders (SLD) and pervasive developmental disorders (PDD). DEVELOPMENT:Clinical concordance studies in twins and in vertical familial groups suggest polygenic multifactorial modes of inheritance, but in some...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-01 00:00:00
abstract：INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-10-16 00:00:00
abstract：TITLE:Consanguinidad y enfermedad mental grave en los primeros Borbones españoles. ...
journal_title：Revista de neurologia
pub_type： 评论,信件
doi：10.33588/rn.7108.2020438
更新日期：2020-10-16 00:00:00
abstract：TITLE:Encefalitis multifocal como manifestación neurológica de la infección por COVID-19. ...
journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.7109.2020226
更新日期：2020-11-01 00:00:00
abstract：TITLE:Uso compasivo de cannabidiol en espray para el tratamiento de paraparesia espastica en un paciente con adrenomieloneuropatia. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：
更新日期：2017-06-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVE:It is well known that in aged animals cognitive deficit occurs, homologous with that occurring in Alzheimer's disease in humans, and as has been shown in others species, this may be attenuated by administration of nerve growth factor (NGF). Therefore the basic aim of this study was to make an...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
