[Evoked potentials in the sacred baboon: long-term follow-up of intracerebroventricular infusion of nerve growth factor].

Abstract:

INTRODUCTION AND OBJECTIVE:It is well known that in aged animals cognitive deficit occurs, homologous with that occurring in Alzheimer's disease in humans, and as has been shown in others species, this may be attenuated by administration of nerve growth factor (NGF). Therefore the basic aim of this study was to make an electrophysiological evaluation of the repercussion that there might be after long-term administration of this neurotropin in the sacred baboon (Papio hamadryas) comparing aged with young animals. MATERIAL AND METHODS:We studied a six year old male and a 39 year old female, after sedation. Long-term intraventricular administration of NGF was carried out using a continuous infusion pump, at a dose of 2.1 micrograms/kg/day. Recordings were made before installing the pump and 1, 3 and 6 months after insertion. A Neuropack Four-mini set for evoked potentials (Nihon Kohden) was used to record auditory evoked potentials from the brain stem and visual evoked potentials due to flash. RESULTS AND CONCLUSION:In both animals there were modifications of their electrophysiological responses. These reached a maximum after one month, more markedly in the older animal and this could possibly be related to the neuromodulator effect of NGF.

journal_name

Rev Neurol

journal_title

Revista de neurologia

authors

Báez MM,Morales L,Fernández CI,Cabrera I,González O,Padilla E,Zaldívar M

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

665-8

issue

7

eissn

0210-0010

issn

1576-6578

journal_volume

28

pub_type

杂志文章
  • [Facial paralysis reported in a paediatric emergency department: actuation protocol reviewed and verified].

    abstract:INTRODUCTION:As result of our aim to improve the quality standard of our emergency system, work has been carried out in relation to the development and monitorization of effective clinical protocols in the department of paediatric practice. PATIENTS AND METHODS:An evidence based review approach was taken to design a c...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Sáenz-Moreno I,Jiménez-Fernández M,López-Pisón J,Miralbés-Terraza S,García-Oguiza A,García-Mata JR,García-Jiménez MC,Campos-Calleja C,Peña-Segura JL

    更新日期:2007-08-16 00:00:00

  • [Spinal cord infarction/ischemia].

    abstract:INTRODUCTION:Vascular pathology is considered to be uncommon, with a much lower incidence than cerebral vascular pathology. PATIENTS AND METHODS:We reviewed the clinical histories of patients with a clinical diagnosis of spinal cord infarction-ischemia attended by the Neurology Department and the Neuropaediatric secti...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Castro-Vilanova MD,de Toledo M,Mateos F,Simón R

    更新日期:1999-11-16 00:00:00

  • [Neuroimaging in preterm infants].

    abstract:INTRODUCTION:It is today well recognised that preterm infants are at risk of neurodevelopmental impairments later in life. The preterm brain is exposed to different stimuli that may affect its normal development. Develoment. Magnetic resonance imaging (MRI) offers the possibility of monitoring normal brain development ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Miranda MJ

    更新日期:2006-10-10 00:00:00

  • [Methodology of basic research in cognitive neuropsychology].

    abstract:INTRODUCTION AND METHOD:The issue regarding the relations between behaviour and the brain is no longer the specific goal of neuropsychology, but rather that of the coordinated multidisciplinary activity of all the disciplines that go to make up the neurosciences. The specific contribution of neuropsychology to this mul...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Benedet MJ

    更新日期:2003-03-01 00:00:00

  • [Overestimation of the degree of stenosis in the intracranial internal carotid artery determined by magnetic resonance angiography compared to conventional arteriography].

    abstract:INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Durán-Ferreras E,Schoeck AP,Barest GD,Viereck JC,Babikian VL,Kase CS

    更新日期:2003-10-16 00:00:00

  • [Electro-clinical concordance for childhood absence epilepsy in monozygotic twins].

    abstract:INTRODUCTION AND OBJECTIVE:The objective of the study was to analyze the EEG tracings during the seizures of two monozygotic twins, shown on molecular analysis, diagnosed as having infantile epilepsy with absences. The recordings are particularly interesting since the genotypes of the patients are identical. This allow...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Trueba MA,Barrasa J,Combarros O,Calleja J

    更新日期:2000-12-16 00:00:00

  • [Characteristics and indications of topiramate].

    abstract:AIM:To evaluate the efficiency of topiramate (TPM), an antiepileptic medication (AEM) which possesses multiple mechanisms of action and good pharmacokinetics, in the different types of childhood epilepsy and to make an appraisal of its value in migraines, bipolar disorder, eating disorders and neuropathic pain, accordi...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Nieto-Barrera M

    更新日期:2002-09-01 00:00:00

  • Facial emotion recognition in neurological disorders: a narrative review.

    abstract::Facial emotion recognition refers to a person's interpretation of facial features of another to identify a particular emotional state. It is essential in human evolution and encompasses distinct neural networks. Facial emotion recognition is altered in most neurodegenerative diseases, but literature just focus on sing...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:10.33588/rn.6905.2019047

    authors: Marco-Garcia S,Ferrer-Quintero M,Usall J,Ochoa S,Del Cacho N,Huerta-Ramos E

    更新日期:2019-09-01 00:00:00

  • [Quantitative and cytomorphometric analysis of glial population in the frontal cortex of contralaterally lesioned rats].

    abstract:INTRODUCTION:In the last years, the changes in glial cells during different alterations in the Central Nervous System have been studied. It is known that astrocytes and microglial cells are the glial cells which present the major reactivity. OBJECTIVE:The aim of this work was to analyze the glial cell changes induced ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Ramírez-Expósito MJ,Martínez-Martos JM

    更新日期:1999-09-01 00:00:00

  • [A brief questionnaire for the diagnosis of maladaptive behavior disorders in adolescents aged between 12 and 16 years of age].

    abstract:OBJECTIVE:To standardize and to determine the structural validity of a conduct disorder self report questionnaire in adolescents. PATIENTS AND METHODS:One hundred ninety, 12 to 16 year old male participants from the different socioeconomic status were randomized selected from educational institutions of Medellin City,...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Pineda DA,Puerta IC,Arango CP,Calad OM,Villa MT

    更新日期:2000-06-16 00:00:00

  • [The epidemiology of multiples sclerosis in Alcoi. Analytical data].

    abstract:INTRODUCTION:The epidemiology of multiple sclerosis (ME) in the Alcoi area has been studied by our groups for many years. When studying the factors linked to ME in this area initially we observed that migration, contact with dogs and the textile industry were associated with the disorder. A later study, in which the mi...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Frutos Alegría MT,Beltrán-Blasco I,Quilez-Iborra C,Moltó-Jordá J,Díaz-Marín C,Matías-Guiu J

    更新日期:2002-05-01 00:00:00

  • [Advantages of neuroendoscopy in the management of non-communicating hydrocephalus].

    abstract:INTRODUCTION:Non-communicating hydrocephalus is defined as a blockade of the physiological cerebrospinal fluid (CSF) flow from the choroid plexus to the subarachnoid space. Usually, a ventricle peritoneal shunt with a valve is employed as treatment but this does not provide a physiological restoration on the CSF flow. ...

    journal_title:Revista de neurologia

    pub_type: 临床试验,杂志文章

    doi:

    authors: Aguas-Valiente J,Ferrer E

    更新日期:1999-08-01 00:00:00

  • [The pathophysiological foundations of the psychiatric disorders in Parkinson's disease].

    abstract:INTRODUCTION:In recent years, the non-motor symptoms of Parkinson's disease, including those of a psychiatric nature, have been receiving greater attention from the scientific community. DEVELOPMENT:In this paper we analyse the pathophysiological bases underlying the different psychiatric symptoms, examining the dopam...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Yáñez-Baña RM

    更新日期:2004-10-01 00:00:00

  • [Early diagnosis of Dravet's syndrome: contributions from clinical practice and molecular biology].

    abstract:INTRODUCTION:Alterations in SCN1A gene cause most cases of Dravet syndrome. This finding has increased scientific interest in the syndrome, helping to better define its clinical features and facilitating treatment. AIMS:To update the knowledge on Dravet syndrome and to discuss the role of the molecular studies in impr...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Sanchez-Carpintero R

    更新日期:2011-06-01 00:00:00

  • [The clinical and economic impact of generic drugs in the treatment of epilepsy].

    abstract:AIMS:The aim of this study was to determine whether the introduction of generic formulations of antiepileptic drugs (AED) would lead to an economic saving for the public health service. DEVELOPMENT:The narrow therapeutic index, low solubility and non-linear pharmacokinetics of some AED mean that the ranges of bioequiv...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Argumosa A,Herranz JL

    更新日期:2005-07-01 00:00:00

  • [The contribution of an intraarterial electroencephalographic study in patients with deep epileptogenic foci].

    abstract:OBJECTIVES:To evaluate the diagnostic efficacy of an intra-arterial electroencephalographic recording and determine which patients obtain most benefit from this technique, to compare the results obtained using other recording techniques and to establish a standard for recording. PATIENTS AND METHODS:We made 64 intra-a...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: García-Asensio S,Guelbenzu S,Barrena MR

    更新日期:2000-04-01 00:00:00

  • [Disappearance of migraine crises in two patients with male infertility treated with human chorionic gonadotropin/human menopausal gonadotrophin].

    abstract::Two patients aged 52 and 31 respectively, treated for male infertility with gonadotrophins (LCG/LMG), showed marked improvement of their migraine crises associated with a typical aura which had been present since puberty. Changes in the number, motility and morphology of the spermatozoids were seen in the seminogram. ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Arango O,Bielsa O,Pascual-Calvet J,Herrero M,Gelabert-Mas A

    更新日期:1996-08-01 00:00:00

  • [Head tremor].

    abstract:INTRODUCTION:Head tremor, either as an isolated symptom or as part of a symptomatic complex, occurs in patients with different neurological diseases. Little research has been carried out to analyse the clinical features of this neurological symptom. AIM:To review the symptomatology, aetiology and therapeutics of brain...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Gironell A,Vives B,Pagonabarraga J

    更新日期:2010-06-01 00:00:00

  • [Cerebral palsy therapy].

    abstract::Unfortunately, in spite of the advances in foetal and perinatal medicine in the last twenty years, the incidence of cerebral palsy has remained unchanged (1.5-2.5 per 1000 live births). It has even possibly risen slightly in premature babies of low birth weight, in parallel with the increased survival of these babies....

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Papazian O,Alfonso I

    更新日期:1997-05-01 00:00:00

  • [Stressful life events as risk factors in acute cerebrovascular disease].

    abstract:INTRODUCTION:The influence of psychosocial stress on the origin of acute cerebral vascular disease (CVD) has received very little attention. The objective of this paper is to evaluate the role of psychosocial stress due to events occurring in daily life as a risk factor (RF) in acute CVD. MATERIAL AND METHODS:A case-c...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Peris A,Martín-González R,Valiente E,Ruiz A,Vioque J

    更新日期:1997-12-01 00:00:00

  • [The possible role of acetaldehyde in the brain damage caused by the chronic consumption of alcohol].

    abstract:AIMS:The purpose of this study is to collect and evaluate the experimental evidence suggesting that acetaldehyde, the first oxidative metabolite of ethyl alcohol (ethanol), plays a mediating role in the brain damage associated with the chronic consumption of this substance. DEVELOPMENT:Although the brain damage associ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Forn-Frías C,Sanchis-Segura C

    更新日期:2003-09-01 00:00:00

  • [Experience with Health Quality of Life Questionnaire for the epileptic child (CAVE)].

    abstract:INTRODUCTION:The practical application of a questionnaire designed to evaluate the quality of life of an epileptic child, known as the CAVE test, is described. This is the first scale of its kind. The test consists of 8 parameters: conduct, attendance at school, learning, independence, social relationships, frequency o...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Casas-Fernández C

    更新日期:1997-03-01 00:00:00

  • [Parkinson's disease in literature, cinema and television].

    abstract::INTRODUCTION. Since James Parkinson published what can be considered the first treaty on the disease that bears his name in 1817, the scientific literature on this pathology has not ceased to grow. But the illness has also been represented in literature, the cinema and on television, where the symptoms, treatment and ...

    journal_title:Revista de neurologia

    pub_type: 历史文章,杂志文章

    doi:

    authors: Collado-Vázquez S,Cano-de-la-Cuerda R,Carrillo JM

    更新日期:2014-02-01 00:00:00

  • [Hereditary ataxias].

    abstract:INTRODUCTION AND OBJECTIVE:The hereditary ataxias form a large, complex group of entities whose recognition is essential for correct genetic assessment, satisfactory clinical control and in some cases a suitable therapeutic approach. The clinico-semiological variety and advances in molecular biology have made the hered...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Ruggieri VL,Arberas CL

    更新日期:2000-08-01 00:00:00

  • [Metabolic imaging by positron emission tomography using [18F] fluorodeoxiglucose in developmental disorders].

    abstract:INTRODUCTION:Developmental disorders are a common pathological condition in Neuropaediatrics and do not usually present characteristic anatomical alterations in the different neuroanatomical imaging tests that can be employed, such as computerised axial tomography or magnetic resonance (MR). Positron emission tomograph...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Maldonado A,Garcia L,Resino MC,Dominguez ML,Muñoz JA,Otero C

    更新日期:2004-02-01 00:00:00

  • [Parkinson's disease, tobacco and age: meta analysis].

    abstract:INTRODUCTION:Epidemiological studies have demonstrated contradictory results about the association between smoking and the risk of Parkinson s disease (PD). OBJECTIVE:Examine the hypothesis of the EUROPARKINSON group that smoking protects against PD only in patients below 75 years of age. MATERIAL AND METHODS:We cond...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,meta分析

    doi:

    authors: Allam MF,del Castillo AS,Navajas RF

    更新日期:2003-03-16 00:00:00

  • [Obstructive sleep apnea syndrome and its relationship with ischaemic stroke].

    abstract:AIM:To describe the main physiopathological mechanisms of obstructive sleep apnea syndrome (OSAS) associated with the development of stroke. DEVELOPMENT:Sleep breathing disorders have a high prevalence in the healthy population, among them, the OSAS is the most recognized. This syndrome has been associated with vascul...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:10.33588/rn.6906.2019061

    authors: Gonzalez-Aquines A,Martinez-Roque D,Baltazar Trevino-Herrera A,Chavez-Luevanos BE,Guerrero-Campos F,Gongora-Rivera F

    更新日期:2019-09-16 00:00:00

  • [Effects of antiepileptics drugs on cognition].

    abstract::The cognitive effects of the most commonly used antiepileptic drugs (AEDs) are reviewed, discussing both the absolute effects (the effects compared to no treatment) and the relative effects (the comparison of one AED with an other). The cognitive profile per AED is given, based on a literature database, consisting of ...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Aldenkamp AP,Vermeulen J

    更新日期:2002-05-01 00:00:00

  • [A clinical and epidemiological description of a series of patients diagnosed as suffering from progressive supranuclear palsy].

    abstract:INTRODUCTION:Progressive supranuclear palsy is a disease that normally presents only sporadically in adults and courses in a progressive, chronic manner. It is characterised by the presence of supranuclear ophthalmoplegia, postural instability, a Parkinsonian syndrome, pseudobulbar affect, cervical dystonia and cogniti...

    journal_title:Revista de neurologia

    pub_type: 杂志文章

    doi:

    authors: Alvarez-González E,Maragoto-Rizo C,Arteche-Prior M,Pérez-Parra S,Carballo M,Alvarez-González L

    更新日期:2004-12-01 00:00:00

  • [Dementia screening in primary care: critical review].

    abstract:INTRODUCTION:Primary care professionals need useful and simple tools to detect early cognitive impairment in patients with any clinical suspicion of dementia. AIM. This critical review attempts to analyze the psychometric properties of cognitive screening tests, commonly used for screening dementia in primary care sett...

    journal_title:Revista de neurologia

    pub_type: 杂志文章,评审

    doi:

    authors: Contador I,Fernández-Calvo B,Ramos F,Tapias-Merino E,Bermejo-Pareja F

    更新日期:2010-12-01 00:00:00