Abstract：
AIMS:The purpose of this study is to collect and evaluate the experimental evidence suggesting that acetaldehyde, the first oxidative metabolite of ethyl alcohol (ethanol), plays a mediating role in the brain damage associated with the chronic consumption of this substance. DEVELOPMENT:Although the brain damage associated with the chronic consumption of ethanol is multifactorial and, possibly, dependent on the numerous actions of this substance on the central nervous system (CNS), there is data to suggest that the oxidative metabolism of ethanol and resulting substances are involved in the aetiology of such processes. Similarly, the generation of free radicals and the formation of adducts between the products of this metabolism and substrates contained in the CNS could be the main mediators in such pathological processes. This idea is supported by the fact that the adducts derived from the metabolism of ethanol are formed in the same areas of the brain as those which present structural and functional disorders in chronic consumers of alcohol. CONCLUSIONS:There are currently different experimental findings that appear to support the proposal that the substances resulting from the metabolism of ethanol can be important mediators in the brain damage associated with the chronic consumption of alcohol. Although more research is required, this theoretical proposal is very interesting, not just because of its relative novelty, but also because it is based on the same principles put forward to explain the toxic effects of alcohol consumption on organs and tissues.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Forn-Frías C,Sanchis-Segura Csubject
Has Abstractpub_date
2003-09-01 00:00:00pages
485-93issue
5eissn
0210-0010issn
1576-6578pii
rn2003194journal_volume
37pub_type
杂志文章,评审abstract：:In this paper we review the relation between epilepsy and the law, more precisely with regard to penal and civil law. Since the new Spanish penal code came into effect in 1996, and especially in view of recent advances in medical knowledge, it is important for doctors and lawyers to make an effort to develop a languag...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-03-16 00:00:00
abstract：AIM AND DEVELOPMENT:To debate about the application of on-going 'revolutions' in medical knowledge to Spanish neurological journals in the 21st century. This article reviews the current status of five revolutions in the field of health sciences, in general, and in neurological sciences, in particular: 1) the knowledge ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-01-16 00:00:00
abstract：INTRODUCTION:CLIPPERS syndrome (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory process of the central nervous system whose distinguishing features are the enhancing punctiform lesions in the brainstem that appear in the magnetic resonance images. Clinic...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2013-10-16 00:00:00
abstract：INTRODUCTION:Neuronal ceroid lipofuscinosis (NCL), represents a group of inherited neurodegenerative disorders. Based on the age of the patient at onset, clinical course and ultrastructural morphology it has been identified three clinical types for the pediatric group: 1) Infantile NCL (INCL); 2) Late infantile NCL (LI...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：PURPOSE AND SETTING:To describe the prevalence and risk factors for carotid stenosis in TIA/stroke patients with non valvular atrial fibrillation (AF) and to compare clinical and CT characteristics of TIA/stroke in AF patients with and without carotid stenosis. SUBJECTS:50 TIA/stroke patients with AF who had ultrasoun...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：INTRODUCTION:Decompression sickness (DS) is caused when bubbles of an inert gas usually nitrogen, since oxygen is metabolised in the tissues are released into the bloodstream and tissues during fast ascents once the atmospheric pressure is lowered near the surface. Neurological complications are its most serious form o...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:Theories about consciousness are in an initial state of development. In the recent past, diverse theories have been proposed to explain the phenomenon of the consciousness using the Quantum Mechanics (QM) as a fundamental tool. Here, we criticize some of these theories in the light of the current knowledge in...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-01 00:00:00
abstract：INTRODUCTION:Purely bulbar hematomas are not common (0.25%-0.50% of all intraparenchymatous hematomas), probably because of the particular characteristics of the anatomy and hemodynamics of the bulbar circulation. CLINICAL CASES:We selected 18 cases. Three of these were our own and the purely bulbar localization was c...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION:Cerebral vasculitis embraces a wide range of conditions that are characterised by involvement of the vessels of the central nervous system (CNS) due to inflammation of their walls, which in turn leads to occlusion or the formation of aneurysms with the ensuing ischaemic-haemorrhagic disorders this produces...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：INTRODUCTION:Mirror writing is a rare disorder in which the patient's handwriting is done backwards and a mirror is needed to be able to read it. Although mirror writing presents both spontaneously and pathologically, it is mainly due to cerebrovascular lesions in the dominant hemisphere. CASE REPORT:A right-handed 62...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-12-16 00:00:00
abstract：INTRODUCTION:Restless legs is an unpleasant sensation in the calves that occurs when the individual is sitting or laying down, with an irresistible urge to move the legs. It has been know as a cause of insomnia. We have been using various drugs with a variety of effectiveness. Levodopa is now considered the drug of cho...
journal_title：Revista de neurologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-05-16 00:00:00
abstract：INTRODUCTION:Functional hemispherectomy consists in palliative epilepsy surgical procedure usually performed in patients with pharmaco-resistant epilepsy and hemispheric syndromes. It is based on the neural disconnection of the affected hemisphere with preservation of the vascular supply. AIM:To analyze long-term prog...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-03-01 00:00:00
abstract：INTRODUCTION:Stroke is a leading cause of mortality and disability. Policosanol has been effective in brain ischemia models. The aim of this study is to investigate whether policosanol, added to aspirin therapy within 30 days of stroke onset, is better than placebo + aspirine for the long-term recovery of non-cardioemb...
journal_title：Revista de neurologia
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2017-02-16 00:00:00
abstract：INTRODUCTION:The end of our century has been characterized by a quick scientific and technological growth. Among other, the brain, the human genome project and the computer science, they are some of the numerous fields that characterize this revolution. DEVELOPMENT:In the following work, we will show as these three fi...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2001-09-16 00:00:00
abstract：OBJECTIVE:To present the first Spanish case, perhaps the first non-Canadian, with ataxia type Charlevoix-Saguenay. CLINICAL CASE:A patient with important psychomotor delay and non-progressive ataxia has been studied in our Service during the first years of life and his follow-up has been carried out until 30 years of ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：INTRODUCTION:Currently, clinical benefits of stroke units and thrombolysis in ischaemic stroke are evidence-based. However, inequities in coverage and in treatment provided to these patients still persist due to geographical differences in residence, technological capacity and organization among health care systems. Te...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：:Epilepsy is a neurological disorder that affects 1-2% of the population. Despite the available treatments (drug therapy, resective surgery, vagus nerve stimulation), there is a significant subgroup of patients that continues to have disabling seizures. The indications of deep brain stimulation are exponentially growin...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-07-16 00:00:00
abstract：TITLE:Telemedicina en pediatría del neurodesarrollo durante la pandemia de COVID-19: experiencia en un hospital terciario. ...
journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.7112.2020554
更新日期：2020-12-16 00:00:00
abstract：:Neuroinflammation is a key process in the neuropathogenesis of AIDS virus since as a result of the aberrant activation of the chemokine receptors (CXCR4, CX3CR1 and CR5) produces proinflammatory cytokine release by infected cells, increases microglial neurotoxicity and generates lipoperoxides and reactive oxygen speci...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-16 00:00:00
abstract：INTRODUCTION:Congenital hydrocephalus or ventriculomegaly is a disorder that now can be diagnosed in uterus with ultrasonography, this gives the chance of being able to give a treatment the earliest as possible. DEVELOPMENT:The clinical manifestations are reviewed, the diagnosis, the frequent treatment and causes of c...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-10 00:00:00
abstract：INTRODUCTION:Cultural manifestations are frequently used as a source of descriptors in the field of the health sciences. The story of Odysseus (Ulysses) is one of the oldest and most influential works of world literature and has given rise to many subsequent creations, with strong roots in popular culture. AIMS:To con...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：10.33588/rn.7103.2020187
更新日期：2020-08-01 00:00:00
abstract：AIMS:To review the fundamentals of occupational therapy (OT) and to present its possible contributions in the field of neurological rehabilitation. DEVELOPMENT:As its name suggests, OT is a form of treatment that makes use of occupations. Furthermore, occupation is a purpose itself, since OT seeks to adapt the individ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-16 00:00:00
abstract：INTRODUCTION:The epidemiology of multiple sclerosis (ME) in the Alcoi area has been studied by our groups for many years. When studying the factors linked to ME in this area initially we observed that migration, contact with dogs and the textile industry were associated with the disorder. A later study, in which the mi...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:The new insights presented at the 5th Joint Triennial Congress of the European and Americas Committees on Treatment and Research in Multiple Sclerosis (ECTRIMS and ACTRIMS) held in Amsterdam, the Netherlands, 19-22 October 2011, have been summarized at the fourth edition of Post-ECTRIMS meeting held in Madrid in Novem...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2012-06-16 00:00:00
abstract：OBJECTIVE:To present the current concepts of the clinical phenomenology and natural history of Gilles de la Tourette syndrome (GTS), differential diagnosis with other involuntary movements, its pathogenesis and current management. DEVELOPMENT:GTS is a disorder characterized by a spectrum of both motor and sonic tics, ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
abstract：AIMS:The study reviews language disorders in children. Taking their normal development as the starting point, the work puts forward a differential diagnosis based on the symptoms presented in the moment the patient visited the physician. It also suggests an approach for children with language disorders from the neuropa...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-06 00:00:00
abstract：INTRODUCTION:Traumatic brain injury (TBI) is a common cause of death and disability in the paediatric population, although the literature on the Spanish population is scarce. From the perspective of early vulnerability, recent research findings suggest that early brain injury has worse sequelae and a higher risk of imp...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.7007.2019393
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION:Dystonia is defined as a sustained co-contraction of agonistic and antagonistic muscles that can cause twisting, twitching and abnormal postures. Occupational dystonias are included in a special group of pathologies that are secondary to a repeated effort related to the professional activity carried out by...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：INTRODUCTION:Latin American medicine in the 16th century produced the first collections of herbs with native plants from the New World. Treatises on popular therapies appeared, which included gallenic remedies as well as incorporating autochthonous plants. We review the main neurological diseases and their treatments d...
journal_title：Revista de neurologia
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2009-08-01 00:00:00
abstract：TITLE:Uso compasivo de cannabidiol en espray para el tratamiento de paraparesia espastica en un paciente con adrenomieloneuropatia. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：
更新日期：2017-06-01 00:00:00
