Abstract:
INTRODUCTION:In the last years, the changes in glial cells during different alterations in the Central Nervous System have been studied. It is known that astrocytes and microglial cells are the glial cells which present the major reactivity. OBJECTIVE:The aim of this work was to analyze the glial cell changes induced by a lesion. MATERIAL AND METHODS:We studied the quantitative and morphometric changes observed in glial cells in the different layers of contralateral frontal cortex using micrometric techniques and image analysis. RESULTS:In contralateral side to the lesions, we observed an increase in the total glial cells in all the cortical layers. The astrocytes only increased their number in cortical layer I, but microglia and oligodendrocytes increased in all the layers. In the cytomorphometric analysis an increase in the nucleus area of astrocytes was observed. CONCLUSION:The glial cell response to the lesions is different for astrocytes, microglia and oligodendrocytes but these changes affected to all the cortical layers.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Ramírez-Expósito MJ,Martínez-Martos JMsubject
Has Abstractpub_date
1999-09-01 00:00:00pages
396-403issue
5eissn
0210-0010issn
1576-6578journal_volume
29pub_type
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