Abstract:
:The neurochemistry of Parkinson's disease and other degenerative parkinsonisms is reviewed, emphasizing the changes described in the dopaminergic system. Presynaptic dopaminergic markers are reduced over the striatum in all these degenerative parkinsonisms, dopamine receptor changes being more heterogeneous. While in Parkinson's disease D1 and D2 receptors remain preserved as compared to controls, in progressive supranuclear palsy there is a loss of nigral D1 receptors and of striatal D2 receptors. This finding has also been described in striatonigral degeneration. There are no clear data about the status of D3, D4 and D5 dopamine receptors in these conditions. The alterations in other neurotransmission systems, cholinegic, adrenergic, serotoninergic and peptidergic are, in general, less dramatic, although they have not been studied in detail. To conclude, further studies are necessary in these field, in these moment, however, the preservation of striatal D2 dopamine receptors is the neurochemical finding with the best correlation with the response to levodopa or other dopaminergic agonists.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Pascual J,Misiego Msubject
Has Abstractpub_date
1997-08-01 00:00:00pages
S141-6eissn
0210-0010issn
1576-6578journal_volume
25 Suppl 2pub_type
杂志文章,评审abstract:INTRODUCTION:Performing amniocentesis between the fourth and sixth months of gestation is a widespread practice. However, it can entail serious consequences, apart from the loss of the foetus, such as injuries to the developing central nervous system. CASE REPORTS:Over the past few years we have dealt with four patien...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:An important aim of neuropsychological assessment is to identify impairment in higher cognitive or intellectual, functioning. In order to achieve this task the assessment of premorbid intellectual ability becomes crucial. The estimation of premorbid cognitive functioning will allow us to assess level of co...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract:AIMS:To appraise the attention deficit hyperactivity disorder assessment scale for a teenage population, EDAH (a). SUBJECTS AND METHODS:From an initial sample of 3400 participants, a final sample of 2292 pupils between 12 and 16 years of age were finally selected. Of the total number, 1066 were boys (46.5%) and 1226 w...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2010-09-16 00:00:00
abstract:INTRODUCTION:Epileptic seizures and epilepsy are part of daily clinical practice in neurology. Yet, the number of false positive diagnoses is surprisingly high. Almost one out of every five patients treated for epilepsy does not really have this diagnosis, which is a high percentage bearing in mind the social and medic...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:10.33588/rn.6806.2018242
更新日期:2019-03-16 00:00:00
abstract:INTRODUCTION:Rett's syndrome (RS) is a disorder of neurological development which is the second commonest cause of mental retardation in girls. It is normally caused by de novo mutations of a gene on the X chromosome. This gene encodes for the protein joining the methyl CpG (MECP2). Mutations of this gene have been fou...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract:TITLE:Síndrome de depleción de ADN mitocondrial tipo 13: un caso con un inicio poco común. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:10.33588/rn.6910.2019221
更新日期:2019-11-16 00:00:00
abstract:INTRODUCTION:Benign idiopathic external hydrocephalus (BIEH) is an age-dependent disorder that is self-limiting in time and has an uncertain aetiology. PATIENTS AND METHODS:A retrospective study was conducted involving 39 patients (16 girls and 23 boys) with BIEH. The following data were analysed for each patient: age...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract::There are several syndromes in which neurological and cutaneous alterations of vascular origin, among other symptoms, occur. The key point of this fact is that these cutaneous signs permit early diagnosis, thus helping in further recognition of more complex syndromes and preventing unnecessary, harmful and costly diag...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1997-09-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:The hereditary ataxias form a large, complex group of entities whose recognition is essential for correct genetic assessment, satisfactory clinical control and in some cases a suitable therapeutic approach. The clinico-semiological variety and advances in molecular biology have made the hered...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-01 00:00:00
abstract:INTRODUCTION:Hirayama disease is a rare children's muscular atrophy that affects young Asian males, with muscular atrophy usually in one of the upper limbs that progresses slowly and later stabilises. It is diagnosed by means of electromyographic/electroneurographic with conduction speed studies (EMG/ENG-CS) and by mag...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To standardize and to determine the structural validity of a conduct disorder self report questionnaire in adolescents. PATIENTS AND METHODS:One hundred ninety, 12 to 16 year old male participants from the different socioeconomic status were randomized selected from educational institutions of Medellin City,...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-06-16 00:00:00
abstract:INTRODUCTION:Hazardous alcohol consumption (HAC) is a pattern of alcohol use that may result in harm for the user and/or for those around them. Prior research has suggested that HAC and alcohol dependence share some neurophysiological features but differ in others. AIM:To determine whether HAC and alcohol dependence p...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2019-02-16 00:00:00
abstract:TITLE:Actos reiterativos y ensayo-error. : ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To observe the frequency of various psychiatric disorders (depressive disorders, anxiety state and paraphrenic-paranoid disorders). PATIENTS AND METHODS:This study includes the 'cases' of dementia detected in an epidemiological field study done door-to-door, double phased and including non-institutionalized ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:Medulloblastoma is a cerebellar small cell tumor, whose ancestor cell has not been yet identified in the human normal embriology: its exact origin is, in fact, still unknown. Nevertheless, one of the most acceptable possibilities facing the origin of the tumor is the remaining rests of cere...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-08-16 00:00:00
abstract:TITLE:Equivalente migrañoso de inicio tardío con aura prolongada y alteración de la perfusión cerebral. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:10.33588/rn.7011.2019333
更新日期:2020-06-01 00:00:00
abstract:INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-10-16 00:00:00
abstract:INTRODUCTION:Meningitis due to Salmonella is an unusual sign of salmonellosis. Usually Salmonella causes clinical disorders of the digestive tract, but on occasions, especially in babies, may cause focalized infections such as meningitis. Although meningitis due to Salmonella is unusual, it should be remembered because...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract:INTRODUCTION AND MATERIAL:Nine brains belonging to early onset Alzheimer disease (E280A-PS1 mutation) affected individuals from Antioquia, Colombia, were analyzed by neuropathological standard techniques. All individuals were ascertained from genealogies descendents from a common ancestor that shows a dominant autosomi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:INTRODUCTION:Functional hemispherectomy consists in palliative epilepsy surgical procedure usually performed in patients with pharmaco-resistant epilepsy and hemispheric syndromes. It is based on the neural disconnection of the affected hemisphere with preservation of the vascular supply. AIM:To analyze long-term prog...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION:Epidemiological studies have demonstrated contradictory results about the association between smoking and the risk of Parkinson s disease (PD). OBJECTIVE:Examine the hypothesis of the EUROPARKINSON group that smoking protects against PD only in patients below 75 years of age. MATERIAL AND METHODS:We cond...
journal_title:Revista de neurologia
pub_type: 杂志文章,meta分析
doi:
更新日期:2003-03-16 00:00:00
abstract:INTRODUCTION:The Iowa Rating Scale for Personality Change (IRSPC) presents some features (puts an emphasis on the motivational and emotional functions; evaluates the 'cognitive' executive functions in the daily life; estimates the premorbid personality; values the informant reliability) that make it use really interest...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Akinetic mutism is considered as an alteration of the motivational state of the person, which the patient is unable to initiate verbal or motor responses voluntary, even with preserved sensorimotor and surveillance functions. CASE REPORT:A 43 year-old male involved in a cerebellum arteriovenous fistula co...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2017-01-16 00:00:00
abstract:INTRODUCTION:Progressive cerebral polidystrophy or Alpers syndrome is a clinico-pathological picture, with no specific biological marker, characterized by involvement mainly of the cerebral grey matter and which shows clinically as a rapidly progressive encephalopathy with intractable seizures, usually myoclonic. The t...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:AIMS:To evaluate the presence of epileptiform discharges and the organisation of nocturnal sleep of autistic children without nocturnal polysomnographic epileptic seizures. SUBJECTS AND METHODS:Cross section analysis. SUBJECTS:21 boys and girls with autistic spectrum using DSM IV criteria between the ages of 4 and 12...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-06-16 00:00:00
abstract:TITLE:Sindrome de Wolf-Hirschhorn: simple omision al citar? Replica. ...
journal_title:Revista de neurologia
pub_type: 评论,信件
doi:
更新日期:2017-09-01 00:00:00
abstract::INTRODUCTION. Dystrophinopathies are X-linked genetic disorders caused by mutations in the DMD gene. Genetic tests are of utmost importance for management and genetic counseling of these diseases. However, the complexity of the DMD gene is a challenge for diagnosis. AIM. To describe recent advances in the diagnosis of...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-02-16 00:00:00
abstract:INTRODUCTION:Developmental disorders are a common pathological condition in Neuropaediatrics and do not usually present characteristic anatomical alterations in the different neuroanatomical imaging tests that can be employed, such as computerised axial tomography or magnetic resonance (MR). Positron emission tomograph...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract::In this study we approach problems related to the dosage and specific action of methylphenidate, its effects at cognitive and social levels, possible side-effects and limitations to its usage, and methods for evaluation of the response to treatment in the school environment. We make special mention of the importance o...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract::It was recently suggested that lacunar strokes presenting with headache may be due to large intracranial artery disease. From the stroke database of the Neurology department, Hospital Sta Maria, we retrieved all lacunar strokes who had investigations of the intracranial circulation. Forty seven of the 208 lacunar stro...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00