Abstract：
INTRODUCTION:There is wide evidence about dopaminergic and noradrenergic mechanisms in fronto-striatal circuits which are thought to be related with attention deficit hyperactivity disorder (ADHD) neurobiology. That dysfunction may explain core symptoms and part of executive deficits in cognitive functioning. Methylphenidate is effective in alleviating core symptoms, enhancing dopaminergic and noradrenergic biodisponibility. Less evidence in improving executive functions, specially working memory is found. AIMS:To assess if methylphenidate-OROS has a potential effect increasing working memory and attention parameters in ADHD children, and to determine if initial working memory and attention differences between ADHD and control group disappear after one month of daily methylphenidate-OROS treatment. SUBJECTS AND METHODS:Eleven children with ADHD were selected and as control group was chosen eleven children compared in age, intelligence quotient, school grade, and social-demographic status. Neuropsychological battery was administered in naive ADHD patients at three times, before treatment, after the first methylphenidate-OROS dose, and after one month of daily treatment. Simultaneously neuropsychological battery was administered to control group. RESULTS. Statistically significant differences were found in neuropsychological variables of working memory after one month daily treatment with methylphenidate-OROS and attention parameters after only one dose in ADHD group. Differences between naive ADHD and control group in terms of working memory were statistically significant before treatment but not after one month daily treatment. CONCLUSION:Methylphenidate-OROS improves attention achievement after the first dose and working memory after one month of daily treatment.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Rubio-Morell B,Martín-González R,Herreros-Rodríguez O,González-Pérez P,Hernández-Exposito S,Quintero-Fuentes I,Gracia-Marco Rsubject
Has Abstractpub_date
2008-05-16 00:00:00pages
602-8issue
10eissn
0210-0010issn
1576-6578pii
rn2008132journal_volume
46pub_type
杂志文章abstract：INTRODUCTION AND OBJECTIVE:We analyze the main factors influencing the time delay between onset and admission to the hospital in acute stroke. PATIENTS AND METHODS:Consecutive series of 1,344 patients with acute stroke or transient ischemic attack admitted at two reference hospitals of Valencia and included at the sam...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：INTRODUCTION:The incidence in the central nervous system diseases has increased with a growing elderly population. Unfortunately, conventional treatments used to treat the mentioned diseases are frequently ineffective due to the presence of the blood brain barrier. AIM:To illustrate the blood-brain barrier properties ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-03-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:Little data has been published in Spain on motor neurone disease or amyotrophic lateral sclerosis. This study reports data on incidence and mortality in Cantabria and incidence in Segovia. It discusses and compares them emphasizing certain characteristic features of the epidemiology of the d...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：1999-11-01 00:00:00
abstract：:Autism spectrum disorder (autism) is a highly prevalent and heterogeneous family of neurodevelopmental disorders of genetic origins with potentially devastating implications for child, family, health and educational systems. Despite advances in paper-and-pencil screening and in standardization of diagnostic procedures...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-02-25 00:00:00
abstract：INTRODUCTION:It is an accepted fact that it is wise to start antiepileptic treatment with monotherapy, but 30% of patients do not respond to it or to several monotherapies; in that moment an association of two or more antiepileptic drugs is commonly utilised (the appearance of ten second-generation antiepileptic drugs ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-07-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 信件
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更新日期：2020-11-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 信件
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更新日期：2019-06-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-02-24 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2016-01-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:An appropriate localization of ictal onset zone in refractory temporal lobe epilepsy favors an adequate outcome associated with surgical treatment. When video-electroencephalogram (video-EEG) and magnetic resonance imaging do not provide accurate data to locate ictal onset zone, the use of subdural or deep...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：INTRODUCTION:Cerebral vasculitis embraces a wide range of conditions that are characterised by involvement of the vessels of the central nervous system (CNS) due to inflammation of their walls, which in turn leads to occlusion or the formation of aneurysms with the ensuing ischaemic-haemorrhagic disorders this produces...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：:Based on the interrelation between science and philosophy, this article addresses the impact of neurosciences on the philosophical issues posed by today's society, especially those related with epistemology and the philosophy of science. To do so, the different approaches in the cognitive sciences are taken into accou...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2013-03-16 00:00:00
abstract：INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-10-16 00:00:00
abstract：INTRODUCTION:Visual phenomena can be symptoms of epileptic seizures, although with an uncertain clinical meaning and relationship with the epileptogenic focus. AIMS:To describe the clinical implications of visual epileptic seizures according to their signs and symptoms in adults. PATIENTS AND METHODS:Data were collec...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-03-16 00:00:00
abstract：INTRODUCTION:This work summarizes current research focused on explaining orientation selectivity of primary visual cortex (V1), and describes the electrophysiological and imaging techniques than are being used. DEVELOPMENT:The study of orientation selectivity in V1 is key to understanding the cortical mechanisms impli...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-05-16 00:00:00
abstract：INTRODUCTION:The early years of life, more especially the first three, are dominated by a series of anatomical-functional facts that express the progressive enrichment of behaviour through the process of neurological maturation, which is expressed as reaching the maximum level of functioning at each stage of developmen...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-06 00:00:00
abstract：INTRODUCTION:Hypnosis is a well known and efficient psychotherapeutic treatment. It has been stated as useful in memory improvement, however, there are only a few reports of this method in teaching, and its neurophysiological aspects. OBJECTIVE:In this paper, the authors were intended to deal with some students' acade...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-08-16 00:00:00
abstract：INTRODUCTION:Behavior disorders are frequently seen in children attending a neuropaediatric clinic. The classical neuroleptic drugs are usually used for treatment. However response tends to be irregular with adverse effects at a cognitive level and extrapyramidal symptoms. PATIENTS AND METHODS:We started to use risper...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：INTRODUCTION:Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal-dominant disorder of peripheral myelin characterized by episodes of recurrent mononeuropathies usually involving nerves at common sites of entrapment and compression. Additional features include evidence of a diffuse demyelinat...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-09-16 00:00:00
abstract：INTRODUCTION:The spinocerebellar ataxia type 2 has a prevalence of 43 per 100,000 inhabitants in Holguín province, which is the highest one reported worldwide. It is due to an intergenerational CAG repeat expansion contained in the first exon of disease causing gene, and it is characterized by a high variability in its...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-12-16 00:00:00
abstract：OBJECTIVES:The published data on neurological resources and the demand for neurological care in Spain were reviewed. Also, this demand was analysed in a specific health district (area 11, Hospital Universitario 12 de Octubre, Madrid). DEVELOPMENT:About 2.5 neurologists per 100,000 inhabitants in Spain was estimated to...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-01 00:00:00
abstract：UNLABELLED:Introduction. Epileptic crises presenting exclusively during sleep are rare and pose more problems of diagnosis than do crises of diurnal presentation. PATIENTS:We present the clinical and electroencephalographic data of 20 patients with exclusively sleep-induced epileptic crises, evaluating not only the ty...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-02-16 00:00:00
abstract：INTRODUCTION:Epilepsy and the epileptic syndromes are common neurological diseases and represent an important public health problem that has given rise to marked social and healthcare concerns. AIM:To analyse the changes in the consumption of antiepileptic drugs in the Basque Country Autonomous Community over a 13 yea...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-04-16 00:00:00
abstract：INTRODUCTION:Congenital malformations of the brain often are complex disorders which display a wide spectrum of neurological manifestations. The presence of this diversity makes it difficult to correlate clinical findings with neuropathological abnormalities or through neuroimaging studies. DEVELOPMENT:Furthermore, th...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-16 00:00:00
abstract：AIM:To contribute to the knowledge of the cognitive differences existent between right-handed and left-handed evaluating the cognitive outcome in a group of adults right-handed and another group of left-handed of similar characteristic (age, gender, cultural level) by means of the Wechsler Adult Intelligence Scale (WAI...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2006-01-16 00:00:00
abstract：INTRODUCTION:Both the normal and pathological development and involution of the CNS are regulated by an important set of both, 'growth factors' (inducing growth, differentiation, survival, adaptation or plasticity in neurons) and 'ageing factors' (inducing involution, atrophy, necrosis or apoptosis). In neurodegenerati...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1997-10-01 00:00:00
