Abstract:
INTRODUCTION:This work summarizes current research focused on explaining orientation selectivity of primary visual cortex (V1), and describes the electrophysiological and imaging techniques than are being used. DEVELOPMENT:The study of orientation selectivity in V1 is key to understanding the cortical mechanisms implicated in the processing of sensory information, but this enterprise has proved more challenging than previously thought and there is no consensus about the best model to explain V1 neurons activity. Ongoing research is focused on determining the importance of the different inputs that a cortical cell receives (thalamic and lateral cortical inputs), and their link to cortical architecture. To achieve that, current research is combining optical imaging techniques with intracellular recordings of V1 neurons. Recent findings have found differences in the synaptic integration performed by neurons located in the iso orientation domains vs orientation centers of the functional V1 map. CONCLUSIONS:Data describing synaptic activity combined with the cortical functional structure are yielding new clues about V1 computation, suggesting that there is more than one mechanism capable of generating orientation selectivity.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Mariño J,Schummers J,Sur Msubject
Has Abstractpub_date
2003-05-16 00:00:00pages
944-50issue
10eissn
0210-0010issn
1576-6578pii
rn2003186journal_volume
36pub_type
杂志文章,评审abstract:INTRODUCTION:Basilar migraine is a particular form of migraine with an aura in which crises of headache are accompanied by symptoms of dysfunction in the vertebro-basilar territory, including alteration of consciousness in the form of stupor or coma. CLINICAL CASES:We report four patients, three men of 14, 17 and 83 y...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract:INTRODUCTION:Vascular lesions produced as a consequence of surgical spinal treatment are rare, but serious. Fast diagnosis and treatment are essential in lesions that produce massive blood loss. Following the use of non covered stents in the treatment of peripheral vascular stenotic obstructive pathologies, the appeara...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-06-16 00:00:00
abstract:AIMS:The purpose of this study is to collect and evaluate the experimental evidence suggesting that acetaldehyde, the first oxidative metabolite of ethyl alcohol (ethanol), plays a mediating role in the brain damage associated with the chronic consumption of this substance. DEVELOPMENT:Although the brain damage associ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2003-09-01 00:00:00
abstract:INTRODUCTION AND AIMS:The dysexecutive questionnaire (DEX) has been used to study executive deficits in both clinical samples (both psychiatric and neurological) and non-clinical samples, although agreement on its factorial structure is lacking. The aim of this research is to study that structure in the self-administer...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Sciatic nerve paralysis is a rare entity in the newborn. Few reference in specialized tests indicate that in the majority of cases the sciatic palsy has been observed after misplaced injections into the buttocks. The prognosis is variable and appears to be better after umbilical vessel catheterization for ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:INTRODUCTION AND CLINICAL CASE:A 58-year-old hypertensive man presented with the sudden onset of quadriplegia and inability to protrude the tongue. Magnetic resonance imaging showed a bilateral medial medullary infarction associated with an abnormally dilated and partially occluded vertebral artery. CONCLUSION:This is...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract:INTRODUCTION:The determination of human leukocyte antigen (HLA) class II genotype is widely used to confirm the diagnosis of narcolepsy with or without cataplexy. The HLA genotyping is reliable, easy to perform and reassures the clinician. It is also less invasive than other methodologies and is in accordance with the ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-01-16 00:00:00
abstract:INTRODUCTION:There is increasing evidence that B cells and humoral immunity play key roles in the pathogenesis of multiple sclerosis (MS). Ocrelizumab, an anti-CD20 monoclonal antibody, has been shown to be effective in controlling the disease and has recently been aproved by the Food and Drug Administration for the tr...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2018-01-01 00:00:00
abstract::A comparative study was carried out to examine urinary excretion of D glucaric acid (DGA), g glutamyltransferase (GGT) activity and the concentration of serum bilirubin as enzymatic induction markers in 89 adult patients (56 men and 33 women) who were receiving chronic treatment with phenobarbital, phenytoin, carbamaz...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-10-16 00:00:00
abstract:INTRODUCTION:Drug abuse is related to neurocognitive alterations linked to the functioning of several areas of the brain. The application of advanced neuroimaging techniques has allowed important advances to be made in research being conducted on why stable disorders are produced in the brain mechanisms responsible for...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-04-01 00:00:00
abstract:INTRODUCTION:The thoracic outlet syndromes are clinical conditions whose true incidence is low, although they are frequently diagnosed. They are caused by compression of the brachial plexus or vascular structures due to anatomical anomalies of the cervico-axillary region. DEVELOPMENT:Two main types are seen: the neuro...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION:It is known as segmental neurofibromatosis type 1 (NF1) a type of NF1 characterized by the features circumscribed to one or more body cutaneous and/or subcutaneous segments. This entity is recognized from recently and it is related with somatic mosaicism. PATIENTS AND METHODS:43 patients (29 females and 1...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-10-16 00:00:00
abstract:INTRODUCTION:Vascular pathology is considered to be uncommon, with a much lower incidence than cerebral vascular pathology. PATIENTS AND METHODS:We reviewed the clinical histories of patients with a clinical diagnosis of spinal cord infarction-ischemia attended by the Neurology Department and the Neuropaediatric secti...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-11-16 00:00:00
abstract:INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-10-16 00:00:00
abstract:INTRODUCTION:Non-ketotic hyperglycinemia is a congenital error in the breakdown of glycine. The most common type is the classical neonatal form, which begins at the age of a few days with symptoms of lethargy, hypotonia, myoclonia, convulsions, apneas and, frequently, ends in death. Survivors usually develop intractabl...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-10-16 00:00:00
abstract:TITLE:Respuesta favorable al uso de inmunoglobulinas intravenosas en la mielinolisis central pontina. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION:The inmuno checkpoints inhibitors are new revolutionary treatment for many neoplastic diseases in advanced stadium. There are described several types of neurological complications induced by nivolumab: polyneuropathy, seizures, radiculitis and myasthenia gravis disease. CASE REPORT:A 65 years old man with...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:10.33588/rn.6808.2018497
更新日期:2019-04-16 00:00:00
abstract:INTRODUCTION:From time to time the debate over whether early-onset epileptic seizures are harmless or have harmful effects on the developing brain reappears. DEVELOPMENT:We evaluated the results of clinical studies reporting the long-term cognitive development of children who suffer from early-onset epilepsies, that i...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-05-21 00:00:00
abstract:INTRODUCTION:The value of the P300 cognitive event-related potential in the diagnosis of Alzheimer subtype neurocognitive disorders is still incipient. Recent studies suggest that combining it with neuropsychological tests by cognitive domains would allow an objective and early characterisation of the cognitive impairm...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:10.33588/rn.7101.2019341
更新日期:2020-07-01 00:00:00
abstract:INTRODUCTION:Face perception involves a broad network of connections between cortical and subcortical regions for the exchange and synchronization of information using white matter fibers. This precise communication system can be affected by the structures and the pathways that connect them. AIMS:To establish the neur...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2017-02-01 00:00:00
abstract:AIMS:The purpose of this study is to review different aspects of mitochondrial myopathies. DEVELOPMENT:Mitochondrial DNA is different to that found in the nucleus and is generally inherited through the mother. There are from 2 to 10 copies per mitochondrion and hundreds or thousands of mitochondria per cell. It contai...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2003-10-16 00:00:00
abstract:INTRODUCTION:The ganglioside GM1 has been shown to be effective in the treatment of experimental cerebral ischemia. Gangliosides from bovine brain have not been used in the treatment of ischemic cerebral accidents. There is evidence suggesting that they may also be effective. RESULTS:Ten minutes of bilateral occlusion...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::The evidence base from empirical studies is one of the elements, along with patients' preference and consideration of particular clinical state and circumstances, that should be taken into account in the process of clinical decision making. This paper provides an overview of the current evidence base for the treatment...
journal_title:Revista de neurologia
pub_type:
doi:
更新日期:2017-02-24 00:00:00
abstract:OBJECTIVES:The published data on neurological resources and the demand for neurological care in Spain were reviewed. Also, this demand was analysed in a specific health district (area 11, Hospital Universitario 12 de Octubre, Madrid). DEVELOPMENT:About 2.5 neurologists per 100,000 inhabitants in Spain was estimated to...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1999-10-01 00:00:00
abstract:INTRODUCTION:The Real Ordinance 2070/1999 meant an important modification in the legislation, when including transcranial Doppler (TCD) in explorations to confirm the clinical diagnosis of brain death (BD). Habitually for their employment in the diagnosis of BD, we look for blood flow signal from the middle cerebral ar...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-11-16 00:00:00
abstract:INTRODUCTION:Trigeminal neuralgia due to vertebrobasilar dolichoectasia is an acquired disease whose true incidence is not known. Microvascular decompression is the most effective technique both for symptomatic relief and for the conservation of nerve structure and function, in spite of the potential complications of a...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-04-16 00:00:00
abstract:INTRODUCTION:The impossibility of treating patients with sleep disorders adequately means that, as specialists, we have to look for new pharmacological treatments and for this reason we examined the information in the paper by Salin Pascual (1999) about the increase in deep sleep when olanzapine is used as an antipsych...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:INTRODUCTION:Valproic acid (VPA) is a drug mainly used to treat epilepsy. Hyperammonaemic encephalopathy due to VPA is a rare but serious complication. The mechanism by which VPA influences the increase in ammonia consists in blocking the urea cycle, thereby inhibiting N-acetylglutamate synthase and diminishing acetyl ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2017-11-01 00:00:00
abstract:INTRODUCTION:The occupational environment generates a large amount of illness which involves several specialities, including neurology. However, there is little awareness--or little training--in this field as in most medical specialities, since in the basic tool of a doctor's work, the clinical history, importance is s...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:INTRODUCTION:It has been previously shown that cluster headache (CH) can involve some extratrigeminal areas. Occipital pain has been recognized in several patients, even as the origin of the attacks. Nevertheless, the proposals of topographic variations of CH have been mainly focused on the location of pain in either s...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-04-01 00:00:00