Abstract:
INTRODUCTION:The theory of memory consolidation, based on the work published by Georg Elias Muller and Alfons Pilzecker over a century ago, continues to guide research into the neurobiology of memory, either directly or indirectly. In their classic monographic work, they concluded that fixing memory requires the passage of time (consolidation) and that memory is vulnerable during this period of consolidation, as symptoms of amnesia appear when brain functioning is interfered with before the consolidation process is completed. Most of the experimental data concerning this phenomenon strongly support the theory. DEVELOPMENT:In this article we present a review of experiments that have made it possible to put forward a model that explains the amnesia produced in conventional learning conditions, as well as another model related to the protection of memory when the same instances of learning are submitted to a situation involving intensive training. CONCLUSIONS:Findings from relatively recent studies have shown that treatments that typically produce amnesia when they are administered immediately after a learning experience (during the period in which the memory would be consolidating itself) no longer have any effect when the instances of learning involve a relatively large number of trials or training sessions, or relatively high intensity aversive events. These results are not congruent with the prevailing theories about consolidation.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Prado-Alcala RA,Quirarte GLsubject
Has Abstractpub_date
2007-09-01 00:00:00pages
284-92issue
5eissn
0210-0010issn
1576-6578pii
rn2006516journal_volume
45pub_type
历史文章,杂志文章,评审abstract:INTRODUCTION:The determination of human leukocyte antigen (HLA) class II genotype is widely used to confirm the diagnosis of narcolepsy with or without cataplexy. The HLA genotyping is reliable, easy to perform and reassures the clinician. It is also less invasive than other methodologies and is in accordance with the ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
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更新日期:2014-01-16 00:00:00
abstract:INTRODUCTION:Parkinson's disease (PD) is a common neurodegenerative disease which begins in adulthood. Its incidence in Mexico is estimated to be 40-50 cases per 100,000 inhabitants/year and is the fourth reason for medical care in the National Institute of Neurology and Neurosurgery. The protein alpha-synuclein, SNCA,...
journal_title:Revista de neurologia
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更新日期:2016-10-16 00:00:00
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journal_title:Revista de neurologia
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journal_title:Revista de neurologia
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更新日期:2019-10-16 00:00:00
abstract:INTRODUCTION:Technological advances have helped to lower the rate of infantile mortality and to raise the survival rate of preterm infants. Thus, studies need to be conducted in this segment of the population, while prematurity continues to be one of the risk factors for neuro-sensory-motor disorders. There is evidence...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Although visual symptoms of multiple sclerosis (MS) are very frequent, they are rarely related with treatment with interferon. This is the first case reported in the literature of retinopathy associated with subcutaneous interferon beta-1a, and the second related to interferons in MS. CASE REPORT:A 30-yea...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-04-16 00:00:00
abstract:INTRODUCTION:Decompression sickness (DS) is caused when bubbles of an inert gas usually nitrogen, since oxygen is metabolised in the tissues are released into the bloodstream and tissues during fast ascents once the atmospheric pressure is lowered near the surface. Neurological complications are its most serious form o...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract:INTRODUCTION:Both the normal and pathological development and involution of the CNS are regulated by an important set of both, 'growth factors' (inducing growth, differentiation, survival, adaptation or plasticity in neurons) and 'ageing factors' (inducing involution, atrophy, necrosis or apoptosis). In neurodegenerati...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1997-10-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
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更新日期:2006-02-16 00:00:00
abstract:TITLE:Parálisis súbita de la supraversión de la mirada en una niña de 9 años. : ...
journal_title:Revista de neurologia
pub_type: 信件
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更新日期:2020-11-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2017-05-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2018-01-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2009-11-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:10.33588/rn.6901.2019079
更新日期:2019-07-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-03-03 00:00:00
abstract:INTRODUCTION:Piribedil is a D2 D3 dopamine agonist, which has been shown to be well tolerated and to improve Parkinsonian symptoms, particularly tremor. However, few studies have been published about this Dopamine Agonist as an adjunct to levodopa therapy in patients with Parkinson's disease (PD). This placebo controll...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-04-16 00:00:00
abstract:INTRODUCTION:The cognitive effects of long-term exposure to organic solvents could be similar to those triggered by certain neurodegenerative diseases. AIMS:The purpose of this study was to evaluate the effects exerted by accumulated exposure on the cognitive functions. PATIENTS AND METHODS:105 subjects with an avera...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-16 00:00:00
abstract:INTRODUCTION:Only the organic and cryptogenic forms of frontal lobe epilepsy have been admitted by the ILAE, but according to several reports in the literature, it probably exists also an idiopathic form, at present not well recognized. OBJECTIVE:To study the differences between the organic and the cryptogenic forms o...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION AND AIMS:Mental retardation (MR) affects approximately 2-3% of the general population and around 75% of the known causes of MR are thought to have a genetic origin. The aim of this work is to describe a standardised model of diagnostic approach to patients with mental retardation of a genetic origin (MRGO)...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-07 00:00:00
abstract:INTRODUCTION:Virtual reality allows the user to interact with elements within a simulated scene. In recent times we have been witness to the introduction of virtual reality-based devices as one of the most significant novelties in neurorehabilitation. AIM:To review the clinical applications of the developments based o...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-10-16 00:00:00
abstract:INTRODUCTION:Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal-dominant disorder of peripheral myelin characterized by episodes of recurrent mononeuropathies usually involving nerves at common sites of entrapment and compression. Additional features include evidence of a diffuse demyelinat...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-09-16 00:00:00
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journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION:Lyme disease is a complex infectious disease affecting multiple organic systems. The most frequent complications are of a dermatological, rheumatological, ophthalmological, cardiac and neurological nature. Among the neurological complications, pseudotumour cerebri is considered to be a rare manifestation o...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-04-16 00:00:00
abstract:INTRODUCTION:Status epilepticus (SE) is a condition in which epileptic discharges are sufficiently prolonged or repeated so as to cause persistent changes in neurological function. DEVELOPMENT:At the present time the classification of SE seems to be incomplete and therefore provisional. However the broad subdivision i...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1997-08-01 00:00:00
abstract:AIM:To estimate the prevalence of dementia in the population aged above 65 in the district of Mungialde, Vizcaya. SUBJECTS AND METHODS:We conducted a two-phase door-to-door populational study. The Minimental State Examination and the Pfeiffer questionnaire were used in the screening phase. The Clinical Dementia Rating...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-01-16 00:00:00
abstract::The term 'epileptic equivalent' has had different meanings in recent years, for both doctors and lawyers (who have copied their reports). Our interest is due to finding that in the jurisprudence of the Supreme Court that we have reviewed, these terms are still taken into consideration when passing judgement or declari...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract:INTRODUCTION:In neuropathic pain, as occurs in epilepsy, researchers are striving to find a drug capable of inhibiting the pain-generating ectopic discharges that are produced as a result of neuronal hyperexcitability. This is mediated by ionic exchanges across the channels of the synaptic membrane. This is why the dru...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-10-01 00:00:00
abstract:INTRODUCTION:Meningitis due to Salmonella is an unusual sign of salmonellosis. Usually Salmonella causes clinical disorders of the digestive tract, but on occasions, especially in babies, may cause focalized infections such as meningitis. Although meningitis due to Salmonella is unusual, it should be remembered because...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00