Correction formula for carbamylated haemoglobin in diabetic uraemic patients.

abstract：BACKGROUND:Phlebotomy is a potential cause of preanalytical errors. We have observed phlebotomy in routine practice in a busy Emergency Department, to see how current practice compares with optimal blood sampling. METHODS:Phlebotomy episodes were audited and compared with standard procedures. A computer-based search o...

journal_title：Annals of clinical biochemistry

authors： Berg JE,Ahee P,Berg JD

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Patients with Crigler-Najjar syndrome, type I (CNS-I) have an inherited absence of hepatocellular bilirubin uridine diphosphate-glucuronosyltransferase activity, which results in severe unconjugated hyperbilirubinaemia, often causing kernicterus and death in infancy or childhood. METHODS:Our patient is a 19...

journal_title：Annals of clinical biochemistry

authors： Ihara H,Shino Y,Hashizume N,Shimizu N,Aoki T,Yoshida M

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Interpretative commenting constitutes an important aspect of the post-analytical phase in chemical pathology, but has only recently been the subject of quality assessment. The Royal College of Pathologists of Australasia (RCPA)-Australasian Association of Clinical Biochemists (AACB) Chemical Pathology Patien...

journal_title：Annals of clinical biochemistry

authors： Vasikaran SD,Penberthy L,Gill J,Scott S,Sikaris KA

更新日期：2002-05-01 00:00:00

abstract：:The last 10 years have witnessed radical changes in the definition and diagnosis of the acute coronary syndrome (ACS), including myocardial infarction, as a result of the introduction of sensitive and specific markers of myocardial damage, the cardiac troponins. One barrier to the universal acceptance of these markers...

journal_title：Annals of clinical biochemistry

authors： Lamb EJ,Webb MC,Abbas NA

更新日期：2004-01-01 00:00:00

abstract：:Protoporphyrin and zinc-protoporphyrin were measured in the erythrocytes of normal subjects, workers exposed to lead and patients with iron deficiency and erythropoietic protoporphyria (EPP). Results showed significantly higher levels of zinc-protoporphyrin in the lead-exposed workers (P < 0.0001), patients with iron ...

journal_title：Annals of clinical biochemistry

authors： Nelson JC,Westwood M,Allen KR,Newton KE,Barth JH

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:In a network of laboratories analytical variability between instruments, even of the same type, may exist for reasons beyond the control of laboratory staff. Controlling variability is a prerequisite for the application of shared reference ranges and for ensuring the transferability of patient test results. ...

journal_title：Annals of clinical biochemistry

authors： Jassam N,Lindsay C,Harrison K,Thompson D,Bosomworth MP,Barth JH

更新日期：2011-03-01 00:00:00

abstract：:The effect of ambient temperature on the analytical and clinical performance of a glucose meter was examined. A total of 114 venous whole blood samples were analysed for glucose by a reference method, and by a glucose meter at 21-22 degrees C, room temperatures, 26-27 degrees C and 33-34 degrees C. Glucose meter readi...

journal_title：Annals of clinical biochemistry

authors： Nawawi H,Sazali BS,Kamaruzaman BH,Yazid TN,Jemain AA,Ismail F,Khalid BA

更新日期：2001-11-01 00:00:00

abstract：:A case report is presented of a 37-year-old man who, largely by chance, was found to have a marked mixed hyperlipidaemia. As a teenager he had been treated for apparent idiopathic growth hormone deficiency, but had also never developed secondary sexual characteristics. Pituitary hormone measurement was now consistent ...

journal_title：Annals of clinical biochemistry

authors： Kilpatrick ES,Patmore JE,Rowland-Hill C,Atkin SL

更新日期：2004-07-01 00:00:00

abstract：:Wernicke's encephalopathy is caused by thiamine deficiency and has a range of presenting features, including gait disturbance, altered cognitive state, nystagmus and other eye movement disorders. In the past, Wernicke's encephalopathy was described almost exclusively in the alcohol-dependent population. However, in cu...

journal_title：Annals of clinical biochemistry

authors： Kohnke S,Meek CL

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Ascorbic acid can interfere with methodologies involving redox reactions, while comprehensive studies on main chemistry analysers have not been reported. We therefore attempted to determine the interference of ascorbic acid with analytes on the Beckman Synchron LX20. METHODS:Various concentrations of ascorb...

journal_title：Annals of clinical biochemistry

authors： Meng QH,Irwin WC,Fesser J,Massey KL

更新日期：2005-11-01 00:00:00

abstract：:An audit of troponin measurement protocols in use in Wales showed significant variations in practice with no consensus on analytical methods, or in the selection of a decision limit for the diagnosis of myocardial damage. Peer review data on assay imprecision at concentrations approaching the analytical limit of detec...

journal_title：Annals of clinical biochemistry

authors： Thomas MA,Singh GK,Williams EJ,McDowell IF,Tovey JA,Wayte AM,All Wales Clinical Biochemistry Audit Group.

更新日期：2005-09-01 00:00:00

abstract：:The levels of thyroid hormones in paired venous and capillary serum samples taken from 68 healthy full-term neonates were determined by radioimmunoassay. Compared with capillary values, total thyroxine (T4), thyrotropin (TSH) and thyroxine-binding globulin (TBG) each showed a significant decrease in venous serum. The ...

journal_title：Annals of clinical biochemistry

authors： O'Grady CM,Franklin RC

更新日期：1984-07-01 00:00:00

abstract：:Simultaneous localisation of the isoenzymes of alkaline phosphatase and gamma-glutamyl transferase was carried out on 173 serum samples from patients with hepatobiliary and bone disease to determine (i) if a better discrimination of the underlying pathology could be obtained by such an approach, and (ii) if the pathol...

journal_title：Annals of clinical biochemistry

authors： Baines M

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:In humans, leptin circulates in a free form and is also bound to macromolecules. The aim of the present study was to compare a rapid acid-ethanol precipitation (AEP) method of measuring bound leptin with the more laborious gel exclusion chromatography (GEC) reference procedure. Serum samples collected from h...

journal_title：Annals of clinical biochemistry

authors： Jamieson NB,McMillan DC,Brown DJ,Wallace AM

更新日期：2003-03-01 00:00:00

abstract：:A sensitive radioimmunoassay method for sodium cromoglycate in human plasma is described. The lowest quantifiable concentration of sodium cromoglycate is 0.93 nmol/l when 0.1 ml plasma samples are analysed. Direct analysis of sodium cromoglycate concentrations in plasma samples collected up to several hours after the ...

journal_title：Annals of clinical biochemistry

authors： Brown K,Gardner JJ,Lockley WJ,Preston JR,Wilkinson DJ

更新日期：1983-01-01 00:00:00

abstract：:The two stages of a two-site immunoradiometric assay were investigated separately. In the first stage, the amount of ferritin bound to coated tubes initially showed a rapid increase with increasing concentration of added ferritin. This was followed by a plateau and then a further increase which appeared to be largely ...

journal_title：Annals of clinical biochemistry

authors： Perera P,Worwood M

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:The haptoglobin (Hp) 2-2 phenotype has been known to have less antioxidative activity than Hp 1-1 and Hp 2-1. However, few have reported the relationship between oxidative stress and Hp phenotypes by using oxidized LDL. The relationship between Hp phenotypes and oxidative stress was therefore investigated in...

journal_title：Annals of clinical biochemistry

authors： Lee YW,Min WK,Chun S,Lee W,Park H,Lee YK,Lee DH,Son JE

更新日期：2004-11-01 00:00:00

abstract：:Background Measured (MO) and calculated osmotic concentrations (CO) and the osmotic gap (OG) are commonly used in the investigation of electrolyte and volume disturbances as well as in cases of suspected volatile ingestion. Methods We compared 38 published formulae for CO with MO on a large data-set ( n = 9466) and ad...

journal_title：Annals of clinical biochemistry

authors： Wilgen U,Pretorius CJ,Ungerer JP

更新日期：2018-01-01 00:00:00

abstract：:It is our aim to summarise and discuss procedures for the evaluation of the concentration of free ionised calcium in serum or plasma. Stress is laid upon the interrelations and relative validity of the most common algebraic expressions to appraise the calcium status. The multitude of formulae proposed in the literatur...

journal_title：Annals of clinical biochemistry

authors： Vanstapel FJ,Lissens WD

更新日期：1984-09-01 00:00:00

abstract：:The analytical and biological components of variation of total cholesterol, high density lipoprotein (HDL) cholesterol, HDL3 cholesterol, HDL2 cholesterol and apolipoproteins A-I and B in serum were assessed in 12 apparently healthy individuals. All analytes showed marked individuality and therefore conventional popul...

journal_title：Annals of clinical biochemistry

authors： Ford RP

更新日期：1989-05-01 00:00:00

abstract：:Background Faecal occult blood testing is an important diagnostic tool for the detection of colorectal cancer. However, it has not been standardized due to the absence of suitable specimens for surveillance. Methods We developed a ready-to-use artificial stool made from rice flour. This new artificial stool homogeneou...

journal_title：Annals of clinical biochemistry

authors： Miike A,Ogawa Z,Sakurabayashi I

更新日期：2018-05-01 00:00:00

abstract：:A binding assay for sex hormone binding globulin (SHBG) has been developed in which SHBG is saturated with tritiated dihydrotestosterone (DHT). Separation of bound and free DHT is achieved by using Concanavalin A-Sepharose as a solid phase matrix. The method is described and its performance, including linearity, impre...

journal_title：Annals of clinical biochemistry

authors： Whittaker JA,Cawood ML,Oakey RE

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Biological variation of an analyte is an important determinant of its usefulness. Intraindividual variation in serum thyroid hormones, parathyroid hormone (PTH) and insulin-like growth factor-1 (IGF-1) in healthy subjects was determined in this study. METHODS:Blood samples were taken at weekly intervals for...

journal_title：Annals of clinical biochemistry

authors： Ankrah-Tetteh T,Wijeratne S,Swaminathan R

更新日期：2008-03-01 00:00:00

abstract：:Background Measurement of serum dexamethasone during the overnight dexamethasone-suppression test has been recommended to reduce false-positive results when investigating Cushing's syndrome or increasingly commonly found adrenal incidentalomas. Despite this, there remains a paucity of well-validated dexamethasone meth...

journal_title：Annals of clinical biochemistry

authors： Hawley JM,Owen LJ,Debono M,Newell-Price J,Keevil BG

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:We found a unique cholesteryl ester transfer protein (CETP) deficient case with markedly elevated serum triglyceride (TG) as well as high-density lipoprotein cholesterol (HDL-C) levels. Most of the CETP deficiency cases were reported to have normal or reduced serum TG with elevated HDL-C. METHODS:The case s...

journal_title：Annals of clinical biochemistry

authors： Ai M,Tanaka A,Shimokado K,Ohtani R,Inazu A,Kobayashi J,Mabuchi H,Nakano T,Nakajima K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUNDS:Diabetic patients with end-stage renal disease who are not on haemodialysis show low concentrations of HbA1c and glycated albumin due to renal anaemia and proteinuria, respectively. In the present study, we examined whether serum albumin-adjusted glycated albumin could accurately reflect glycaemic control i...

journal_title：Annals of clinical biochemistry

authors： Fukami K,Shibata R,Nakayama H,Yamada K,Okuda S,Koga M

更新日期：2015-07-01 00:00:00

abstract：:Serum osteocalcin did not show any response to the onset of osteosarcoma in Paget's disease of bone whereas serum alkaline phosphatase increased rapidly. This suggests that osteocalcin is not useful in the diagnosis and management of Paget's osteosarcoma and does not reflect the same osteoblastic processes in bone as ...

journal_title：Annals of clinical biochemistry

authors： Davie MW,Worsfold M,Sharp CA

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Thiopurine methyltransferase (TPMT) catalyses the S-methylation of 6-thiopurine drugs, which are commonly used in the treatment of autoimmune diseases, leukaemia and organ transplantation. TPMT activity is polymorphic as a result of gene mutations. Ethnic variations in phenotype and genotype have been identi...

journal_title：Annals of clinical biochemistry

authors： Laróvere LE,de Kremer RD,Lambooy LH,De Abreu RA

更新日期：2003-07-01 00:00:00

abstract：:The effect of acetate and bicarbonate haemodialysis (HD) on the concentrations of erythrocyte, whole-blood and plasma total carnitine (TC), free carnitine (FC), short- (SC) and long-chain acylcarnitine (LC) and acylcarnitine (AC) as well as the ratio of AC to FC was investigated in 30 healthy subjects (15 men and 15 w...

journal_title：Annals of clinical biochemistry

authors： Alhomida AS

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Serum triglyceride concentrations are measured as total glycerides content in many Western countries. In Japan, glycerol-blanked triglycerides (TG-GB) are measured to identify postprandial hypertriglyceridaemia and to minimize the influence of glycerol formulation on serum triglyceride values. However, TG-GB...

journal_title：Annals of clinical biochemistry

authors： Koyama I,Imano H,Nakamura M,Kitamura A,Kiyama M,Miyamoto Y,Iso H

更新日期：2020-05-01 00:00:00