Abstract:
:An in vitro system which uses perifused pieces from the antrum of rat stomach has been used to study the effect of dihydrosomatostatin on gastrin release. The gastrin concentration in fractions of the perfusate was measured by radioimmunoassay. Dihydrosomatostatin (2 x 10-7M) had no effect on basal gastrin levels but virtually abolished the biphasic response seen with argine stimulation. The study demonstrates close functional similarities between G cells and pancreatic islet cells.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Hayes JR,Johnson DG,Koerker D,Williams RHdoi
10.1210/endo-96-6-1374subject
Has Abstractpub_date
1975-06-01 00:00:00pages
1374-6issue
6eissn
0013-7227issn
1945-7170journal_volume
96pub_type
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