Effects of progesterone and tamoxifen on glucocorticosteroid-induced egg-white protein synthesis in the chick oviduct.

abstract：:Anandamide and 2-arachidonoylglycerol (2-AG), two endogenous ligands of the CB1 and CB2 cannabinoid receptor subtypes, inhibit the proliferation of PRL-responsive human breast cancer cells (HBCCs) through down-regulation of the long form of the PRL receptor (PRLr). Here we report that 1) anandamide and 2-AG inhibit th...

journal_title：Endocrinology

authors： Melck D,De Petrocellis L,Orlando P,Bisogno T,Laezza C,Bifulco M,Di Marzo V

更新日期：2000-01-01 00:00:00

abstract：:PTH increases calcium reabsorption exclusively in the distal nephron. Two mechanisms of Ca++ transport through the basolateral membrane (BLM) have been described: the ATP-dependent and the sodium gradient-dependent transport. In the present study, we investigated the effect of PTH and (Bu)2cAMP on these two mechanisms...

journal_title：Endocrinology

authors： Bouhtiauy I,Lajeunesse D,Brunette MG

更新日期：1991-01-01 00:00:00

abstract：:To examine the physiological effects of norepinephrine (NE) in the paraventricular nucleus of the hypothalamus (PVH) on CRF gene expression and CRF release, NE was microinjected bilaterally into the PVH of conscious rats, and kinetic studies were performed on the levels of POMC messenger RNA (mRNA) in the anterior pit...

journal_title：Endocrinology

authors： Itoi K,Suda T,Tozawa F,Dobashi I,Ohmori N,Sakai Y,Abe K,Demura H

更新日期：1994-11-01 00:00:00

abstract：:In thyroid epithelial cells, TSH via cAMP induces a rounding up of the cells associated with actin stress fiber disruption, expression of differentiation genes and cell cycle progression. Here we have evaluated the role of small G proteins of the Rho family and their impact on the actin cytoskeleton in these different...

journal_title：Endocrinology

authors： Fortemaison N,Blancquaert S,Dumont JE,Maenhaut C,Aktories K,Roger PP,Dremier S

更新日期：2005-12-01 00:00:00

abstract：:Activin A is a member of the transforming growth factor-beta family of growth factors and a potent regulator of cellular activity. A number of binding proteins for activin A have been identified, including alpha 2-macroglobulin (alpha 2M). Alpha 2M has several conformational states that are known to have different gro...

journal_title：Endocrinology

authors： Niemuller CA,Randall KJ,Webb DJ,Gonias SL,LaMarre J

更新日期：1995-12-01 00:00:00

abstract：:We have studied the relationship between the levels of the alpha and beta subunit of TSH and alpha and TSH-beta mRNA content in pituitaries from euthyroid, short-term, and long-term hypothyroid mice and in various mouse TSH-secreting tumors. TSH, alpha, and TSH-beta were determined by specific radioimmunoassay. alpha ...

journal_title：Endocrinology

authors： Gurr JA,Kourides IA

更新日期：1984-08-01 00:00:00

abstract：:The proliferation and differentiation of testicular progenitor stem cells into highly specialized germ cells (spermatozoa) are largely controlled by the hormonally (FSH and testosterone) regulated adjacent supporting Sertoli cells. However, the factors involved in this control remain largely unknown. In the present st...

journal_title：Endocrinology

authors： Hellani A,Ji J,Mauduit C,Deschildre C,Tabone E,Benahmed M

更新日期：2000-08-01 00:00:00

abstract：:Parathyroid hormone (PTH) secretion rate was measured in seven calves by using a technique which involved RIA of parathyroid venous blood collected during timed intervals and measured volumetrically. Infusion of solutions of NA2EDTA and MgCl2 into the jugular vein was used to alter plasma calcium and magnesium concent...

journal_title：Endocrinology

authors： Mayer GP,Hurst JG

更新日期：1978-06-01 00:00:00

abstract：:Leukemia Inhibitory Factor (LIF) and its receptors in human and mouse pituicytes are expressed abundantly in corticotrophs and somatotrophs. As LIF induces POMC transcription and LPS-mediated stress also induces hypothalamic and pituitary LIF expression, we studied ACTH secretion in LIF knockout (LIF KO) mice. Basal A...

journal_title：Endocrinology

authors： Akita S,Malkin J,Melmed S

更新日期：1996-07-01 00:00:00

abstract：:PTH, via the PTH/PTH-related protein receptor type 1 that couples to both protein kinase A (PKA) and protein kinase C (PKC) pathways, and the canonical Wnt-beta-catenin signaling pathway play important roles in bone formation. In the present study we have examined the interaction between the PTH and Wnt signaling path...

journal_title：Endocrinology

authors： Tobimatsu T,Kaji H,Sowa H,Naito J,Canaff L,Hendy GN,Sugimoto T,Chihara K

更新日期：2006-05-01 00:00:00

abstract：:Atrial, brain-type, and C-type natriuretic peptides (ANP, BNP, and CNP) act via receptors with intrinsic guanylate cyclase activity. The A-type and B-type ANP receptors are selectively activated by ANP and CNP, respectively. The anterior pituitary is a site of ANP production and action, suggesting a local regulatory f...

journal_title：Endocrinology

authors： McArdle CA,Poch A,Käppler K

更新日期：1993-05-01 00:00:00

abstract：:Adipokines, cytokines mainly produced by adipocytes, are active participants in the regulation of inflammation. Administration of zymosan (ZY) was used to investigate the regulation and role of adipokines during peritonitis in mice. Injection of ZY led to a significant increase in leptin levels in both serum and perit...

journal_title：Endocrinology

authors： Pini M,Gove ME,Sennello JA,van Baal JW,Chan L,Fantuzzi G

更新日期：2008-08-01 00:00:00

abstract：:We used the library subtraction technique to identify genes specifically expressed in the rat uterus during early pregnancy. One such gene was that for stathmin, a factor that is associated with tubulin binding and the destabilization of microtubules. Stathmin was expressed at higher levels in implantation sites than ...

journal_title：Endocrinology

authors： Tamura K,Hara T,Yoshie M,Irie S,Sobel A,Kogo H

更新日期：2003-04-01 00:00:00

abstract：:Early life exposure to immunological challenge has programming effects on the adult hypothalamo-pituitary-adrenocortical axis stress responsivity, and stress is known to suppress GnRH pulse generator activity, especially LH pulses. We investigated the effects of neonatal exposure to endotoxin on stress-induced suppres...

journal_title：Endocrinology

authors： Li XF,Kinsey-Jones JS,Knox AM,Wu XQ,Tahsinsoy D,Brain SD,Lightman SL,O'Byrne KT

更新日期：2007-12-01 00:00:00

abstract：:Sclerostin (SOST), a member of the cystine-knot superfamily, is essential for proper skeletogenesis because a loss-of-function mutation in the SOST gene results in sclerosteosis featured with massive bone growth in humans. To understand the function of SOST in developmental skeletal tissue formation, we examined SOST ...

journal_title：Endocrinology

authors： Ohyama Y,Nifuji A,Maeda Y,Amagasa T,Noda M

更新日期：2004-10-01 00:00:00

abstract：:TGF-β plays an important role in the progression of prostate cancer. It exhibits both tumor suppressor and tumor-promoting activities. Correlations between cyclooxygenase (COX)-2 overexpression and enhanced production of prostaglandin (PG)E2 have been implicated in cancer progression; however, there are no studies ind...

journal_title：Endocrinology

authors： Vo BT,Morton D Jr,Komaragiri S,Millena AC,Leath C,Khan SA

更新日期：2013-05-01 00:00:00

abstract：:Previous studies have shown that aldosterone plus salt loading cause cardiac hypertrophy in rats in vivo, and that in vitro, both aldosterone and glucose stimulate fibroblast growth. The present studies examined the effects of adrenal steroids via mineralocorticoid and glucocorticoid receptors (MR and GR) on [3H]leuci...

journal_title：Endocrinology

authors： Sato A,Funder JW

更新日期：1996-10-01 00:00:00

abstract：:Oxytocin receptor (OTR) expression in human myometrium increases over 150-fold from the beginning of pregnancy to the end. In the present studies, we examined potential mechanisms of OTR up-regulation, using myometrial cells in primary culture from women in late gestation. OTR ligand-binding sites and steady-state mRN...

journal_title：Endocrinology

authors： Jeng YJ,Soloff SL,Anderson GD,Soloff MS

更新日期：2003-01-01 00:00:00

abstract：:Dispersed pancreatic islet cells were analyzed for their low forward angle light scatter using flow cytometry. The cells produced a distinct light scatter pattern which appeared to be a function of cell size and not cell granularity. RIA of hormone content of cells collected from different regions of the pattern revea...

journal_title：Endocrinology

authors： Fletcher DJ,Grogan WM,Barras E,Weir GC

更新日期：1983-11-01 00:00:00

abstract：:Atrial Natriuretic Factor (ANF) has been demonstrated within the central nervous system (CNS), where it has been implicated in the regulation of blood pressure, fluid and electrolyte balance. To explore the effect of acute plasma vol expansion on the activation of CNS ANF, changes in ANF levels of CSF drawn from the c...

journal_title：Endocrinology

authors： Cameron VA,Espiner EA

更新日期：1990-11-01 00:00:00

abstract：:Photoaffinity labeling with underivatized T3 was used to identify T3-binding proteins in the membrane of rat erythrocytes. UV irradiation of ghosts and peripheral protein-depleted membranes in the presence of [125I]T3 resulted in the covalent attachment of 125I to membrane proteins (analyzed by polyacrylamide gel elec...

journal_title：Endocrinology

authors： Samson M,Osty J,Blondeau JP

更新日期：1993-06-01 00:00:00

abstract：:Congenital adrenal hyperplasia is a group of common inherited disorders leading to glucocorticoid deficiency. Most cases are caused by 21-hydroxylase deficiency (21OHD). The systemic consequences of imbalanced steroid hormone biosynthesis due to severe 21OHD remains poorly understood. Therefore, we developed a zebrafi...

journal_title：Endocrinology

authors： Eachus H,Zaucker A,Oakes JA,Griffin A,Weger M,Güran T,Taylor A,Harris A,Greenfield A,Quanson JL,Storbeck KH,Cunliffe VT,Müller F,Krone N

更新日期：2017-12-01 00:00:00

abstract：:Ghrelin, a novel 28 amino acid peptide found in hypothalamus and stomach, was recently identified as the endogenous ligand for the growth hormone secretagogue receptor (GHS-R). We have now found that both intracerebroventricular (i.c.v.) and intraperitoneal (i.p.) administration of ghrelin in freely feeding rats stimu...

journal_title：Endocrinology

authors： Wren AM,Small CJ,Ward HL,Murphy KG,Dakin CL,Taheri S,Kennedy AR,Roberts GH,Morgan DG,Ghatei MA,Bloom SR

更新日期：2000-11-01 00:00:00

abstract：:We have studied calmodulin (CaM)-like activity and calcium (Ca++)-regulated phosphodiesterase (PDE) activity in cells from the rat adrenal zona glomerulosa (ZG) and zona fasciculata (ZF). Boiled cell sonicates from the ZG and ZF activated CaM-deficient PDE in a dose-dependent fashion by 2.0- to 2.3-fold. The propertie...

journal_title：Endocrinology

authors： Koletsky RJ,Brown EM,Williams GH

更新日期：1983-08-01 00:00:00

abstract：:Neuropeptide Y (NPY) is a powerful orexigenic factor, and alphaMSH is a melanocortin (MC) peptide that induces satiety by activating the MC4 receptor subtype. Genetic models with disruption of MC4 receptor signaling are associated with obesity. In the present study, a 7-day intracerebroventricular infusion to male rat...

journal_title：Endocrinology

authors： Raposinho PD,Castillo E,d'Alleves V,Broqua P,Pralong FP,Aubert ML

更新日期：2000-12-01 00:00:00

abstract：:Thyroid hormone (T3) is required for postnatal skeletal growth. It exerts its effect by binding to nuclear receptors, TRs including TRα1 and TRβ1, which are present in most cell types. These cell types include chondrocytes and osteoblasts, the interactions of which are known to regulate endochondral bone formation. In...

journal_title：Endocrinology

authors： Desjardin C,Charles C,Benoist-Lasselin C,Riviere J,Gilles M,Chassande O,Morgenthaler C,Laloé D,Lecardonnel J,Flamant F,Legeai-Mallet L,Schibler L

更新日期：2014-08-01 00:00:00

abstract：:Agouti-related protein (AgRP) expressed in the arcuate nucleus is a potent orexigenic neuropeptide, which increases food intake and reduces energy expenditure resulting in increases in body weight (BW). Glucocorticoids, key hormones that regulate energy balance, have been shown in rodents to regulate the expression of...

journal_title：Endocrinology

authors： Shibata M,Banno R,Sugiyama M,Tominaga T,Onoue T,Tsunekawa T,Azuma Y,Hagiwara D,Lu W,Ito Y,Goto M,Suga H,Sugimura Y,Oiso Y,Arima H

更新日期：2016-04-01 00:00:00

abstract：:The vertebrate adenohypophysis forms as a placode at the anterior margin of the neural plate, requiring both hedgehog (Hh) and fibroblast growth factor (Fgf) mediated cell-cell signaling for induction and survival of endocrine cell types. Using small molecule inhibitors to modulate signaling levels during zebrafish de...

journal_title：Endocrinology

authors： Guner B,Ozacar AT,Thomas JE,Karlstrom RO

更新日期：2008-09-01 00:00:00

abstract：:Female Wistar-Furth rats were implanted sc with GH3 rat pituitary tumor cells. Tumors were palpable by 4 weeks, and animals were killed periodically from 5-9 weeks. Tumor-bearing rats (n = 10) were heavier than their respective controls, reaching a weight of 372 +/- 3 by 9 weeks vs. 195 +/- 5 g in controls (mean +/- S...

journal_title：Endocrinology

authors： Yamashita S,Slanina S,Kado H,Melmed S

更新日期：1986-03-01 00:00:00

abstract：:The beta-subunit of hCG (hCG beta) displays immunological cross-reactivity with human LH (hLH). A detailed study was undertaken to investigate the effect of chemical and enzymatic modifications on the immunological behavior of hCG beta, particularly on its cross-reactivity with hLH, with a view to obtaining a highly h...

journal_title：Endocrinology

authors： Ghai RD,Mise T,Pandian MR,Bahl OP

更新日期：1980-11-01 00:00:00