The pharmacology underlying pharmacotherapy for tobacco dependence: a focus on bupropion.

abstract：:Sulphonylureas (SUs) and biguanides (metformin) are the current mainstays in the treatment of type 2 diabetes (T2DM) and represent the most commonly used oral hypoglycaemic agents (OHAs). In recent years, a variety of new OHAs have become available, including thiazolidinediones, glinides, alpha-glucosidase inhibitors,...

journal_title：International journal of clinical practice

authors： Philippe J,Raccah D

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Cariprazine is an oral antipsychotic approved in the US for the treatment of schizophrenia, acute bipolar mania, and most recently, bipolar depression. The aim of this systematic review is to describe the efficacy, tolerability and safety of cariprazine for the treatment of depressive episodes associated with...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2019-10-01 00:00:00

abstract：:The aim of this study was to review the application of antimicrobial stewardship principles to the management of community-acquired pneumonia (CAP). Data from 14 published clinical studies, meta-analyses and practice guidelines regarding the application of antimicrobial stewardship strategies to the management of CAP ...

journal_title：International journal of clinical practice

authors： Bosso JA,Drew RH

更新日期：2011-07-01 00:00:00

abstract：:Summary The objective of this study was to determine whether Ramadan is changing frequencies and demographics of visits due to certain diseases. Data obtained from the charts of the adult patients admitted into the emergency department (ED) due to 10 predetermined entities between 2000 and 2004 were analysed. Demograp...

journal_title：International journal of clinical practice

authors： Topacoglu H,Karcioglu O,Yuruktumen A,Kiran S,Cimrin AH,Ozucelik DN,Sarikaya S,Soysal S,Turpcu U,Bozkurt S

更新日期：2005-08-01 00:00:00

abstract：:The wide variation in the way coronary artery disease (CAD) affects different ethnic groups and the associated risk factor profiles of these groups have been extensively studied, but ethnic differences in the clinical manifestations of peripheral vascular disease (PVD) have been relatively neglected. The aim of the pr...

journal_title：International journal of clinical practice

authors： Makin A,Silverman S,Lip GY

更新日期：2002-10-01 00:00:00

abstract：:Splenic tumours are occasionally found during routine physical check-ups or elective abdominal image studies. Histologically, most splenic tumours are of benign vascular origin. To avoid unnecessary surgery for asymptomatic patients with benign splenic tumours and clarify the clinicopathological features of spleen tum...

journal_title：International journal of clinical practice

authors： Chen LW,Chien RN,Yen CL,Chang LC

更新日期：2004-10-01 00:00:00

abstract：AIMS:Studies of antimuscarinics for overactive bladder (OAB) typically use objective and subjective measures to assess efficacy, as each provides unique information about patient outcome. We evaluated the relationships between changes in diary-documented OAB symptoms and other patient-reported outcome (PRO) measures. ...

journal_title：International journal of clinical practice

authors： Crosby RD,Mathias SD,Marshall TS

更新日期：2011-02-01 00:00:00

abstract：:Nitrates are useful drugs in cardiovascular medicine. They have a presumed vasovagal effect, which is a rare but often under-recognised complication that is partly caused by central inhibition of the sympathetic nervous system. However, no consistent variable associated with the presumed vasovagal effects following ni...

journal_title：International journal of clinical practice

authors： Lydakis C,Chaudary AY,Lip GY

更新日期：1998-09-01 00:00:00

abstract：:A 39-year-old entertainer was referred in November 2000 for suspected secondary hypothroidism found during a routine insurance check. Thyroid stimulating hormone (TSH) was 0.30 mIU/L (NR 0.47-4.68 mIU/L) and total T4 was 21.6 nmol/l (NR 57.9-154.4 nmol/l). She had enjoyed good past health and gave birth to a baby girl...

journal_title：International journal of clinical practice

authors： Chan WB,Chow CC,Cockram CS

更新日期：2004-10-01 00:00:00

abstract：:Proton pump inhibitors are highly effective acid suppressants with decades of use highlighting positive outcomes in millions of patients worldwide, and they offer minimal risk of adverse events. PPIs are considered overutilised when prescribed without an appropriate indication, when patients are left on them 'indefini...

journal_title：International journal of clinical practice

authors： Heidelbaugh JJ,Metz DC,Yang YX

更新日期：2012-06-01 00:00:00

abstract：:Prostate cancer remains a most intriguing condition, which poses unique challenges. On reviewing recent literature on localised disease (confined within the capsule T1 or T2, N0, M0), it would seem that it is over treated, resulting in significant morbidity. We now have strong evidence, however, that there can be mort...

journal_title：International journal of clinical practice

authors： Hodgson D,Acher P,Cahill D

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The impact of hip fracture because of a fall on health-related quality of life (HRQoL) and activities of daily living (ADL) have not been well established. AIM:To evaluate changes in HRQoL and the ability to conduct ADL among patients with hip fracture because of a fall and to compare these changes with pat...

journal_title：International journal of clinical practice

authors： Orive M,Aguirre U,García-Gutiérrez S,Las Hayas C,Bilbao A,González N,Zabala J,Navarro G,Quintana JM

更新日期：2015-04-01 00:00:00

abstract：AIMS:We prospectively enrolled 207 patients (121 were 75 or older and 86 younger than 75) who were admitted to three Respiratory Monitoring Units. The primary outcomes were intubation and mortality rates; the secondary outcomes were changes in arterial blood gases analysis, non-invasive ventilation (NIV) duration and l...

journal_title：International journal of clinical practice

authors： Nicolini A,Santo M,Ferrera L,Ferrari-Bravo M,Barlascini C,Perazzo A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Budesonide/formoterol is an effective treatment for both asthma and chronic obstructive pulmonary disease. This study compared the efficacy and safety of a novel hydrofluoroalkane (HFA) pressurised metered-dose inhaler (pMDI) formulation of budesonide/formoterol with that of budesonide pMDI and budesonide/fo...

journal_title：International journal of clinical practice

authors： Morice AH,Peterson S,Beckman O,Osmanliev D

更新日期：2007-11-01 00:00:00

abstract：:Over the past years, there has been an explosive increase in the prevalence of type 2 diabetes (T2DM) and this is expected to continue, entailing associated morbidity and mortality. An increasing number of studies explore the different ways T2DM could be prevented. On-going lifestyle modifications need to be addressed...

journal_title：International journal of clinical practice

authors： Gruber A,Nasser K,Smith R,Sharma JC,Thomson GA

更新日期：2006-05-01 00:00:00

abstract：:Kaposi's sarcoma (KS) is a recognised complication following kidney transplantation, but the incidence varies according to the geographical area. Although it is a rare tumour, its incidence increases dramatically after solid-organ transplantation. The immunosuppressive medications reactivate human herpes virus 8, whic...

journal_title：International journal of clinical practice

authors： Kolhe N,Mamode N,Van der Walt J,Pattison J

更新日期：2006-11-01 00:00:00

abstract：:The diagnosis of acute renal infarction (ARI) is often delayed or unrecognised because of its non-specific presentation and the rarity of the disease. We evaluated the clinical presentations, laboratory findings, underlying medical conditions and treatment of 18 Chinese patients with ARI who presented to the emergency...

journal_title：International journal of clinical practice

authors： Tsai SH,Chu SJ,Chen SJ,Fan YM,Chang WC,Wu CP,Hsu CW

更新日期：2007-01-01 00:00:00

abstract：:Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...

journal_title：International journal of clinical practice

authors： Demirel F,Bideci A,Camurdan MO,Cinaz P

更新日期：2007-08-01 00:00:00

abstract：:The misery of living with atopic eczema (syn. dermatitis, AD) cannot be overstated for it may have a profoundly negative effect on the health-related quality of life (HRQoL) of children and their family unit in many cases. As it is one of the commonest chronic relapsing childhood dermatosis (UK lifetime prevalence 16-...

journal_title：International journal of clinical practice

authors： Lewis-Jones S

更新日期：2006-08-01 00:00:00

abstract：AIM:The aim of this study was to compare ezetimibe/simvastatin combination therapy with intensified statin monotherapy as alternative treatment strategies to achieve the Joint British Societies (JBS)-2 and National Institute for Health and Clinical Excellence low-density-lipoprotein cholesterol (LDL-C) target of < 2 mm...

journal_title：International journal of clinical practice

authors： McCormack T,Harvey P,Gaunt R,Allgar V,Chipperfield R,Robinson P,IN-PRACTICE study.

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Medication errors are a frequent cause of adverse drug events and a major concern for patient safety. This study compared the predictors of error among seven countries (Australia, Canada, New Zealand, the United Kingdom, the United States, Germany and the Netherlands). METHODS:We conducted a cross-sectional ...

journal_title：International journal of clinical practice

authors： Lu CY,Roughead E

更新日期：2011-07-01 00:00:00

abstract：:Influences on bladder health begin during infancy and continue throughout the lifespan. Bladder anatomy and physiology change as individuals age, and the risk and propensity for bladder conditions, including lower urinary tract symptoms, throughout life are related to factors specific to age, sex, and life events. Bla...

journal_title：International journal of clinical practice

authors： Ellsworth P,Marschall-Kehrel D,King S,Lukacz E

更新日期：2013-05-01 00:00:00

abstract：:Primary palmar hyperhidrosis is a disabling disorder that starts in childhood and causes physical and psychological inconvenience. Conservative treatment is not effective in severe cases. Thoracoscopic sympathectomy is the treatment of choice. It is a safe minimally invasive procedure with good results. There are few ...

journal_title：International journal of clinical practice

authors： Rashid HI,Osman HS,McIrvine AJ

更新日期：1998-11-01 00:00:00

abstract：AIMS:To describe trends and outcomes during admission for solid organ transplant in people with or without type 2 diabetes in Spain, 2001-2015. METHODS:We used national hospital discharge data to select all hospital admissions for kidney, lung, heart, and liver transplant. We estimated admission rates stratified by ty...

journal_title：International journal of clinical practice

authors： de Miguel-Yanes JM,Jiménez-García R,de Miguel-Díez J,Hernández-Barrera V,Méndez-Bailón M,Muñoz-Rivas N,López-de-Andrés A

更新日期：2018-10-13 00:00:00

abstract：AIM:Variations of dopamine receptor type 2 (DRD2) are among the key factors involved in the pathology of schizophrenia. Presence of certain SNPs in DRD2 gene also amend patients' response to antipsychotics. Keeping in view the genetic diversity among populations and important role of DRD2 polymorphisms in schizophrenia...

journal_title：International journal of clinical practice

authors： Amir QU,Hanif F,Washdev W,Bilwani F,Usman Simjee S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Guidelines for injury care are increasingly moving away from surgical management towards less invasive procedures but there is a knowledge gap on how these recommendations are influencing practice. We aimed to assess inter-hospital variation in surgical intensity for injury admissions and evaluate the correl...

journal_title：International journal of clinical practice

authors： Patton MP,Moore L,Farhat I,Tardif PA,Gonthier C,Belcaid A,Lauzier F,Turgeon A,Clément J

更新日期：2020-11-01 00:00:00

abstract：AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...

journal_title：International journal of clinical practice

authors： Drake MJ,MacDiarmid S,Chapple CR,Esen A,Athanasiou S,Cambronero Santos J,Mitcheson D,Herschorn S,Siddiqui E,Huang M,Stoelzel M

更新日期：2017-05-01 00:00:00

abstract：AIM:To determine the prevalence of computer vision syndrome (CVS) and ergonomic practices among students in the Faculty of Medical Sciences at The University of the West Indies (UWI), Jamaica. METHOD:A cross-sectional study was done with a self-administered questionnaire. RESULTS:Four hundred and nine students partic...

journal_title：International journal of clinical practice

authors： Mowatt L,Gordon C,Santosh ABR,Jones T

更新日期：2018-01-01 00:00:00

abstract：:Acute pulmonary oedema can sometimes complicate adenotonsillectomy carried out for obstructive sleep apnoea. Early recognition and adequate oxygenation are the key to management. We report such a case; the pathophysiology and management of this rare complication of a common procedure are discussed. ...

journal_title：International journal of clinical practice

authors： Motamed M,Djazaeri B,Marks R

更新日期：1999-04-01 00:00:00

abstract：:Thyroid cancer is uncommon with an estimated lifetime risk of 0.8% for women and 0.3% for men. The incidence appears to be increasing by 4% per year and is currently the eighth commonest cancer in women. Managing thyroid cancer is challenging, as no prospective randomised trials exist. Most of the information is deriv...

journal_title：International journal of clinical practice

authors： Nix P,Nicolaides A,Coatesworth AP

更新日期：2005-11-01 00:00:00