Relationships between symptoms, symptom bother, and health-related quality of life in patients with overactive bladder taking solifenacin or placebo in the VIBRANT study.

abstract：:This randomised, double-blind, placebo-controlled, parallel-group study compared the efficacy and tolerability of lumiracoxib (a novel COX-2 selective inhibitor) with rofecoxib, celecoxib and placebo in patients with moderate-to-severe post-operative dental pain. Following third molar extraction, patients received sin...

journal_title：International journal of clinical practice

authors： Kellstein D,Ott D,Jayawardene S,Fricke J

更新日期：2004-03-01 00:00:00

abstract：INTRODUCTION:Erectile dysfunction (ED) is common in older age and in diabetes mellitus (DM). Phosphodiesterase type 5-inhibitors (PDE5-is) are the first-line for ED. We investigated how the type of diabetes and age of males affect the PDE5-i use in the primary care setting. METHODS:From 2018 to 2019, the general pract...

journal_title：International journal of clinical practice

authors： Stedman M,Whyte MB,Lunt M,Albanese M,Livingston M,Gadsby R,Hackett G,Anderson SG,Heald AH

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:The ENDURANCE study evaluated the efficacy of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor, in men with erectile dysfunction (ED), by measuring the duration of erection leading to successful intercourse using a stopwatch as the assessment instrument. METHODS:This was a randomised, multicentre, dou...

journal_title：International journal of clinical practice

authors： Rosenberg MT,Adams PL,McBride TA,Roberts JN,McCallum SW

更新日期：2009-01-01 00:00:00

abstract：:An increasing number of patients aged>or=70 years are presenting for elective non-cardiac surgery. We undertook this study to: (i) compare the nature and distribution of cardiovascular disease (CVD) risk factors in an at risk population of patients aged>or=70 years undergoing elective surgery compared with a younger a...

journal_title：International journal of clinical practice

authors： Naughton C,Feneck RO

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The decision on whether or not to treat a first seizure is dependent on several medical and non-medical factors. AIMS:In this review, we have summarised the important aspects that determine the advantages and disadvantages of treating a first seizure. We have looked at evidence from randomised controlled tr...

journal_title：International journal of clinical practice

authors： Sathasivam S,Nicolson A

更新日期：2008-12-01 00:00:00

abstract：:People in a first episode of psychosis are receiving increasing attention. This study describes the demographic and clinical diagnostic features of a cohort of 84 cases of first episode psychosis presenting in North Derbyshire from October 1999 to October 2000. Forty-two cases falling within the schizophrenia spectrum...

journal_title：International journal of clinical practice

authors： Rowlands RP

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Studies in the primary care setting are of high interest for assessing the management situation of patients with manifestations of atherothrombosis. AIMS:Therefore, we documented diagnostic procedures, characteristics, and management of patients with symptomatic and asymptomatic peripheral arterial disease ...

journal_title：International journal of clinical practice

authors： Kröger K,Schwertfeger M,Pittrow D,Diehm C

更新日期：2010-06-01 00:00:00

abstract：:Nitrates are useful drugs in cardiovascular medicine. They have a presumed vasovagal effect, which is a rare but often under-recognised complication that is partly caused by central inhibition of the sympathetic nervous system. However, no consistent variable associated with the presumed vasovagal effects following ni...

journal_title：International journal of clinical practice

authors： Lydakis C,Chaudary AY,Lip GY

更新日期：1998-09-01 00:00:00

abstract：:A 60-year-old man noticed rapid enlargement of a long-standing thyroid goitre, with dysphagia and difficulty in breathing. Thyrotoxicosis was diagnosed. Chest X-ray revealed multiple pulmonary metastases. He underwent near-total thyroidectomy. The histopathology revealed an undifferentiated thyroid carcinoma with some...

journal_title：International journal of clinical practice

authors： Plengvidhya N,Rathanavijitrasilp A,Sangruchi T,Nitiyanant W,Vannasaeng S,Piraphatdist T,Vichayanrat A

更新日期：1997-10-01 00:00:00

abstract：:Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells. It also exhibits antibacterial activity against Helicobacter pylori in vitro. During almost 10 years of clinical use, lansoprazole has prove...

journal_title：International journal of clinical practice

authors： Bown RL

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Malnutrition is a crucial health problem predominantly in the developing countries. Malnutrition in children is one of the main risk factors for diseases and mortality. Club foot or congenital talipes equinovarus (CTEV) is the most common form of congenital orthopaedic abnormality. Over the past 20 years, th...

journal_title：International journal of clinical practice

authors： Muzzammil M,Mughal A,Qadir A,Mughal A,Effendi J,Bhatti A,Minhas MS

更新日期：2020-12-20 00:00:00

abstract：AIMS:To establish the value of the first 3 years of a cardiovascular risk factor clinic in tackling the major risk factors for cardiovascular disease (CVD). METHODS:A database review of all 339 patients referred to the clinic. RESULTS:Blood pressure levels in the hypertensive patients were significantly reduced and 9...

journal_title：International journal of clinical practice

authors： Martin SC,Viljoen A

更新日期：2008-06-01 00:00:00

abstract：:Splenic tumours are occasionally found during routine physical check-ups or elective abdominal image studies. Histologically, most splenic tumours are of benign vascular origin. To avoid unnecessary surgery for asymptomatic patients with benign splenic tumours and clarify the clinicopathological features of spleen tum...

journal_title：International journal of clinical practice

authors： Chen LW,Chien RN,Yen CL,Chang LC

更新日期：2004-10-01 00:00:00

abstract：:Osteoporosis results from a decrease in bone strength yielding increased susceptibility to fractures. Hip and spine fractures are a major cause of morbidity and mortality in the elderly population. With an increasingly ageing world population, early prevention of bone loss is essential for adequate control of this con...

journal_title：International journal of clinical practice

authors： Reginster JY,Malaise O,Neuprez A,Bruyere O

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:A significant proportion of COVID-19 patients may have cardiac involvement including arrhythmias. Although arrhythmia characterization and possible predictors were previously reported, there are conflicting data regarding the exact prevalence of arrhythmias. Clinically applicable algorithms to classify COVID...

journal_title：International journal of clinical practice

authors： Rav-Acha M,Orlev A,Itzhaki I,Zimmerman SF,Fteiha B,Bohm D,Kurd R,Samuel TY,Asher E,Helviz I,Glikson M,Michowitz Y

更新日期：2020-10-30 00:00:00

abstract：:Monomeric prolactin (PRL) of molecular weight 23 kDa constitutes up to 95% of adult serum PRL. Macroprolactin is a large antigen-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating PRL. Thus, in most cases, hyperprolactinaemia is usually a result of high levels of mono...

journal_title：International journal of clinical practice

authors： Sadideen H,Swaminathan R

更新日期：2006-04-01 00:00:00

abstract：:Identification and modification of risk factors can prevent strokes. Certain previously unidentified risk factors for stroke can become apparent following admission with acute stroke. The aim of the study was to investigate the prior capture, identification and management of modifiable risk factors for stroke in patie...

journal_title：International journal of clinical practice

authors： Gupta A,Thomas P

更新日期：2002-06-01 00:00:00

abstract：:Thyroid cancer is uncommon with an estimated lifetime risk of 0.8% for women and 0.3% for men. The incidence appears to be increasing by 4% per year and is currently the eighth commonest cancer in women. Managing thyroid cancer is challenging, as no prospective randomised trials exist. Most of the information is deriv...

journal_title：International journal of clinical practice

authors： Nix P,Nicolaides A,Coatesworth AP

更新日期：2005-11-01 00:00:00

abstract：AIMS:To investigate the diagnostic value of the International Prostate Symptom Score (IPSS) voiding-to-storage subscore ratio (IPSS-V/S) in male lower urinary tract symptoms (LUTS). METHODS:A total of 253 men with LUTS were enrolled from January 2005 to July 2010. The voiding (IPSS-V) and storage IPSS (IPSS-S) subscor...

journal_title：International journal of clinical practice

authors： Liao CH,Chung SD,Kuo HC

更新日期：2011-05-01 00:00:00

abstract：:Zoledronic acid inhibits bone resorption for up to 12 months. It is not known whether the duration of this antiresorptive effect extends beyond this period of time. The aim of this study was to evaluate the changes in bone turnover at 12 months (T12) and 18 months (T18) after a single injection of 4 mg of zoledronic a...

journal_title：International journal of clinical practice

authors： Borba VZ,Paz-Filho G,Kulak CA,Seibel MJ,Bilezikian JP

更新日期：2007-06-01 00:00:00

abstract：:We present one of the rarer causes of pregnancy-associated jaundice in the immediate puerperium. A 30-year-old multipara with pyruvate kinase deficiency became jaundiced within a few hours of delivery, following an uneventful pregnancy and labour at term. She responded to conservative management, the jaundice clearing...

journal_title：International journal of clinical practice

authors： Esen UI,Olajide F

更新日期：1998-07-01 00:00:00

abstract：:'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...

journal_title：International journal of clinical practice

authors： Fava GA,Tomba E,Sonino N

更新日期：2012-01-01 00:00:00

abstract：AIMS:Early clinical trials suggest that blood-derived stem/progenitor cells (including peripheral blood-derived stem cells and circulating progenitor cells) may have a positive impact on patients with ischaemic heart disease (IHD). The therapeutic effects of these cells remain unclear, considering the inconsistent resu...

journal_title：International journal of clinical practice

authors： Wen Y,Meng L,Ding Y,Ouyang J

更新日期：2011-08-01 00:00:00

abstract：:Hypogonadism may play a significant role in the pathophysiology of erectile dysfunction (ED). A threshold level of testosterone may be necessary for normal erectile function. Testosterone replacement therapy is indicated in hypogonadal patients and is beneficial in patients with ED and hypogonadism. Monotherapy with t...

journal_title：International journal of clinical practice

authors： Shabsigh R,Rajfer J,Aversa A,Traish AM,Yassin A,Kalinchenko SY,Buvat J

更新日期：2006-09-01 00:00:00

abstract：AIMS:Prominent anxiety symptoms are related to poor clinical course and outcome in major depressive disorder (MDD). The aim of this randomised, open-label, controlled study is to compare the efficacy and tolerability of mirtazapine in the form of orally disintegrating tablets against paroxetine in treating MDD patients...

journal_title：International journal of clinical practice

authors： Kim JE,Yoon SJ,Kim J,Jung JY,Jeong HS,Cho HB,Shin E,Lyoo IK,Kim TS

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:The influence of cardiovascular risk factors/comorbidities on response to oral once-daily tadalafil 5 mg was explored in men with lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH). METHODS:This post hoc analysis pooled data from four double-blind studies in which 1498 men wit...

journal_title：International journal of clinical practice

authors： Vlachopoulos C,Oelke M,Maggi M,Mulhall JP,Rosenberg MT,Brock GB,Esler A,Büttner H

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated the beneficial effect of normal and high body mass index (BMI) upon risk of osteoporosis (OP). No study has investigated the prevalence of OP in an older population with a very high BMI (higher than 40 kg/m(2) ). METHODS:Data of patients aged over 50 years that attended for a dual ...

journal_title：International journal of clinical practice

authors： Oldroyd A,Mitchell K,Bukhari M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The incidence of type 2 diabetes is reaching pandemic proportions, impacting patients and healthcare systems across the globe. Evidence suggests that a majority of patients are not achieving recommended blood glucose targets resulting in an increased risk of micro- and macro-vascular complications. AIM:To r...

journal_title：International journal of clinical practice

authors： Woo V,Shestakova MV,Ørskov C,Ceriello A

更新日期：2008-12-01 00:00:00

abstract：:Sexual activity is no more stressful to the heart when compared with a number of other natural daily activities, e.g. walking one mile on the level in 20 minutes. The cardiac risk of sexual activity in patients diagnosed with cardiovascular disease is minimal in properly assessed and advised patients. Erectile dysfunc...

journal_title：International journal of clinical practice

authors： Jackson G,Betteridge J,Dean J,Eardley I,Hall R,Holdright D,Holmes S,Kirby M,Riley A,Sever P

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:Serum sodium overcorrection and hypernatremia are significant health risks. We conducted a systematic review and meta-analysis to evaluate the risks of vaptans in hypernatremia and serum sodium overcorrection. METHODS:We searched PubMed, Embase, and CENTRAL for randomised controlled trials. We included studi...

journal_title：International journal of clinical practice

authors： Zhou Y,Yang W,Liu G,Gao W

更新日期：2020-12-17 00:00:00