Abstract:
OBJECTIVES:A significant proportion of COVID-19 patients may have cardiac involvement including arrhythmias. Although arrhythmia characterization and possible predictors were previously reported, there are conflicting data regarding the exact prevalence of arrhythmias. Clinically applicable algorithms to classify COVID patients' arrhythmic risk are still lacking, and are the aim of our study. METHODS:We describe a single center cohort of hospitalized patients with a positive nasopharyngeal swab for COVID-19 during the initial Israeli outbreak between 1/2/2020 -30/5/2020. The study's outcome was any documented arrhythmia during hospitalization, based on daily physical examination, routine ECG's, periodic 24-hour Holter, and continuous monitoring. Multivariate analysis was used to find predictors for new arrhythmias and create classification trees for discriminating patients with high and low arrhythmic risk. RESULTS:Out of 390 COVID-19 patients included, 28 (7.2%) had documented arrhythmias during hospitalization, including: 23 atrial tachyarrhythmias, combined atrial fibrillation (AF) and ventricular fibrillation, ventricular tachycardia storm, and 3 bradyarrhythmias. Only 7/28 patients had previous arrhythmias. Our study showed significant correlation between disease severity and arrhythmia prevalence (p<0.001) with a low arrhythmic prevalence among mild disease patients (2%). Multivariate analysis revealed background heart failure (CHF) and disease severity are independently associated with overall arrhythmia while age, CHF, disease severity, and arrhythmic symptoms are associated with tachyarrhythmias. A novel decision tree using age, disease severity, CHF, and troponin levels was created to stratify patients into high and low risk for developing arrhythmia. CONCLUSIONS:Dominant arrhythmia among COVID-19 patients is AF. Arrhythmia prevalence is associated with age, disease severity, CHF, and troponin levels. A novel simple Classification tree, based on these parameters, can discriminate between high and low arrhythmic risk patients.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Rav-Acha M,Orlev A,Itzhaki I,Zimmerman SF,Fteiha B,Bohm D,Kurd R,Samuel TY,Asher E,Helviz I,Glikson M,Michowitz Ydoi
10.1111/ijcp.13788subject
Has Abstractpub_date
2020-10-30 00:00:00pages
e13788eissn
1368-5031issn
1742-1241pub_type
杂志文章abstract:BACKGROUND:The regular use of simple analgesics in addition to opioids such as paracetamol (or acetaminophen) is recommended for persistent pain to enhance analgesia. Few studies have examined the frequency and doses of paracetamol among people with chronic non-cancer pain including use above the recommended maximum da...
journal_title:International journal of clinical practice
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abstract::Twenty cases of tuberculous meningitis were diagnosed at the Hamad Medical Corporation between 1990 and 1995. Most of the patients (90%) were expatriates. The most common presenting features were fever, headache, neck stiffness and altered mental status. Five patients were in stage 1 disease at the time of presentatio...
journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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abstract::Fever of unknown origin (FUO) is defined as the body temperature higher than 38.3 degrees C on several occasions and lasting longer than 3 weeks, with the aetiology remaining uncertain after 1 week of investigation. In this study, we reviewed 57 patients with FUO hospitalised in our inpatient department between 1998 a...
journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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abstract:INTRODUCTION:Hyperkalaemia (HK) is associated with increased mortality risk. Prior studies suggest that the causes of HK are multifactorial. This study aimed to examine risk factors for incident and recurrent HK in six large real-world cohorts of UK patients that could be considered at elevated HK risk because of under...
journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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doi:
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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abstract::Asthma treatment is suboptimal in many patients, with impacts on morbidity and mortality, healthcare resource utilisation and patients' quality of life. The reasons for this include the inherent variability of asthma and the unpredictability of exacerbations, which can range from mild to fatal. In addition, asthma can...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13731
更新日期:2021-02-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/ijcp.12044
更新日期:2013-01-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.01109.x
更新日期:2006-10-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2007.01515.x
更新日期:2007-10-01 00:00:00
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
pub_type: 杂志文章,随机对照试验
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journal_title:International journal of clinical practice
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更新日期:2001-05-01 00:00:00
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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更新日期:2004-12-01 00:00:00
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journal_title:International journal of clinical practice
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更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:The objectives of this study were to compare the performance indicators of risk-adjustment models based on administrative and clinical data in Korea, and to assess whether administrative data alone is useful for comparing quality of care. METHODS:Outcome was defined as death within 30 days of discharge. For ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
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更新日期:2007-07-01 00:00:00
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journal_title:International journal of clinical practice
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更新日期:2001-06-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the impact of depression and somatic symptoms on treatment outcomes in Korean male patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) attending a routine clinical practice. METHODS:This was a 12-week prospective observational study (n = 80). The Korean ve...
journal_title:International journal of clinical practice
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更新日期:2014-04-01 00:00:00
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