Abstract：
BACKGROUND:Systolic aortic regurgitation (SAR) is a curious phenomenon that has been found to be associated with heart failure (HF). We aimed to determine de diagnostic value of SAR as a black box predictive tool in patients with suspected HF admitted to hospital with dyspnea as leading symptom. METHODS AND RESULTS:Cross-sectional study including 269 consecutive patients admitted to hospital with dyspnea as leading symptom without definite clinical diagnosis. SAR was defined by echocardiography as the presence of blood flow from the aorta to the left ventricular outflow tract during a complete systole. The reference standard was the presence of HF diagnosis at discharge. SAR was present in 9 (3.3%) patients. Prevalence of HF was 40.3%. Specificity of SAR in the diagnosis of HF was high at 99.4% (95% CI 96.5-99.9%). Sensitivity was 7.5% (95% CI 3.9-14.2%). Positive predictive value (PPV) was 88.9% (95% CI 56.5-98.0%). Positive likelihood ratio was 11.85. Estimated PPV of SAR was significantly higher than 50% for any hypothetical prevalence of HF. CONCLUSION:In patients admitted to hospital with dyspnea, the finding of systolic aortic regurgitation in echocardiography has a high PPV for HF diagnosis at discharge.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Saura D,López-Cuenca A,Oliva MJ,Caballero L,González-Carrillo J,Espinosa MD,López-Ruiz M,García-Navarro M,de la Morena Gdoi
10.1111/ijcp.12566subject
Has Abstractpub_date
2015-04-01 00:00:00pages
485-90issue
4eissn
1368-5031issn
1742-1241journal_volume
69pub_type
杂志文章abstract：:Both the incidence of twin pregnancy and the demand for prenatal diagnosis are increasing. Unfortunately, biochemical screening and ultrasound scanning are less reliable for prenatal diagnosis in twin pregnancies than in singletons. Amniocentesis and chorionic villous biopsy are usually diagnostic in singleton pregnan...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1997-07-01 00:00:00
abstract：:The current study compared the effectiveness of the graduated tuning fork (128 Hz) and the neurothesiometer in assessing vibration sensation perception in patients presenting with type II diabetes mellitus. A quota sample of patients (n = 21; age range 43-73 years) were assessed using the neurothesiometer and tuning f...
journal_title：International journal of clinical practice
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abstract：BACKGROUND:Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, followin...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究,随机对照试验
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journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
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abstract：:Despite its high prevalence, chronic pain is suboptimally treated in approximately one half of affected patients. Failure to recognise and manage comorbid physical and psychosocial impairments may contribute to the perpetuation of chronic pain. Knowledge of the potential advantages and disadvantages of available analg...
journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
pub_type： 共识发展会议,杂志文章,评审
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更新日期：2002-11-01 00:00:00
abstract：:Current and upcoming treatment options for premature ejaculation (PE) are of global clinical interest. In 2008, the International Society for Sexual Medicine published an evidence-based definition for PE. While there are no US Food and Drug Administration-approved therapies for PE, the American Urological Association ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
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abstract：:Sulphonylureas (SUs) and biguanides (metformin) are the current mainstays in the treatment of type 2 diabetes (T2DM) and represent the most commonly used oral hypoglycaemic agents (OHAs). In recent years, a variety of new OHAs have become available, including thiazolidinediones, glinides, alpha-glucosidase inhibitors,...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
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journal_title：International journal of clinical practice
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pub_type： 杂志文章
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journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
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journal_title：International journal of clinical practice
pub_type： 杂志文章
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更新日期：1997-09-01 00:00:00
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journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2002-07-01 00:00:00
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journal_title：International journal of clinical practice
pub_type： 杂志文章
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journal_title：International journal of clinical practice
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更新日期：1999-07-01 00:00:00
