Abstract:
:In recent years the complexities and heterogeneity of polycystic ovarian syndrome (PCOS) have been recognised. Most PCOS sufferers with amenorrhoea, menstrual dysfunction, hirsutism, acne and infertility can be evaluated and safely managed in primary care. It is prudent to remember that all women with PCOS are at risk of insulin resistance and the associated abnormalities of the insulin resistance syndrome--dyslipidaemia, hypertension, coronary artery disease and diabetes mellitus.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Gupta Ssubject
Has Abstractpub_date
1999-07-01 00:00:00pages
359-62issue
5eissn
1368-5031issn
1742-1241journal_volume
53pub_type
杂志文章,评审abstract::'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2011.02825.x
更新日期:2012-01-01 00:00:00
abstract::Antihypertensive efficacy must be redefined beyond blood pressure (BP) lowering per se to include reducing the cardiovascular complications of hypertension. Treatment decisions should be based on results from large clinical trials with relevant clinical outcomes. Several recent morbidity and mortality trials with angi...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2005.00446.x
更新日期:2005-02-01 00:00:00
abstract:AIM:Real-world data on treatment patterns/outcomes in patients with advanced melanoma, while scarce, are useful for health technology assessments that govern patient access in many countries. We collected retrospective data on treatment patterns among patients in France, Germany and the UK with Stage IIIB/IIIC melanoma...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12946
更新日期:2017-05-01 00:00:00
abstract::Hormone replacement therapy (HRT) leads to a similar annual increase in risk of breast cancer as does each extra year of remaining premenopausal. Taken for more than 10 years HRT leads to a 35% increase in risk of developing breast cancer. It does not increase a woman's risk of dying of breast cancer, and may improve ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
abstract::The Diabetes Control and Complications Trial (DCCT) led to considerable improvements in the management of type 1 diabetes, with the wider adoption of intensive insulin therapy to reduce the risk of complications. However, a large gap between evidence and practice remains, as recently shown by the Pittsburgh Epidemiolo...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02296.x
更新日期:2010-02-01 00:00:00
abstract:AIMS:We aimed to assess the prevalence, components and evolution of polypharmacy and to evaluate risk factors associated with polypharmacy. METHODS:A retrospective dynamic cohort study was performed, using a primary healthcare database comprising Flemish community-dwelling adults aged ≥40 years between 2011 and 2015. ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13942
更新日期:2020-12-19 00:00:00
abstract:AIMS:Stress hyperglycaemia during hospitalisation may be the first sign of diabetes mellitus (DM). Most hospitals routinely measure blood glucose, which may enable early diagnosis. This study measured the prevalence of hyperglycaemia in hospitalised adults with no history of diabetes, and whether the discharge summary ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12690
更新日期:2015-11-01 00:00:00
abstract::Of the 25,000 new cases of breast cancer annually in the UK, at least half will develop metastases at some time. Approximately one-third of these will be hormone-sensitive and thus suitable for endocrine manipulation. Such patients may live for several years. Care should be patient-centred and evidence-based, with pri...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2000-12-01 00:00:00
abstract::Snoring is a very common source of complaints from partners and neighbours. Snorers themselves are less likely to be affected, unless they have associated daytime sleepiness caused by the sleep disruption from obstructive sleep apnoea. There is increasingly firm evidence that obstructive sleep apnoea is associated wit...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2003-11-01 00:00:00
abstract::The objective of this study was to investigate the impact of rivastigmine therapy on attention, apathy, anxiety and agitation in patients with mild-to-moderate Alzheimer's disease (AD) in a real-world clinical setting. Patients with mild-to-moderate AD were enrolled in the study by physicians across Canada. They were ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1742-1241.2007.01387.x
更新日期:2007-06-01 00:00:00
abstract:IMPORTANCE:There is an ever-increasing drive to improve surgical patient outcomes. Given the benefits which robotics has bestowed upon a wide range of industries, from vehicle manufacturing to space exploration, robots have been highlighted by many as essential for continued improvements in surgery. OBJECTIVE:The goal...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/ijcp.12492
更新日期:2014-11-01 00:00:00
abstract::The phenomenon of spontaneous remission is one of the less well known aspects of the leukaemias. Spontaneous remission has been reported in both acute and chronic leukaemia. The mechanism is unclear but may involve immune modulation related to an intercurrent infection or transfusion of blood products. We present a ra...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract::It is being questioned if Helicobacter pylori infection, which causes a chronic inflammatory response, can increase the frequency and severity of attacks in patients with Familial Mediterranean Fever (FMF) and if the impact of inflammatory response can be diminished by eradication of the infection. To evaluate if ther...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.01098.x
更新日期:2008-05-01 00:00:00
abstract::Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with gastrointestinal adverse effects, ranging from dyspepsia and peptic ulcer disease to more serious complications such as haemorrhage or perforation. NSAID-induced gastrointestinal toxicity is a significant medical problem worldwide. Misoprostol is effec...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1368-5031.2005.00660.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:We recently described early rigid retrograde endoscopic realignment of the disrupted urethra under caudal anaesthesia in the outpatient setting. This retrospective study was performed to evaluate our medium-term results. PATIENTS AND METHODS:A retrospective review of patients who had early rigid retrograde e...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01481.x
更新日期:2010-01-01 00:00:00
abstract::Linear regression methods try to determine the best linear relationship between data points while correlation coefficients assess the association (as opposed to agreement) between the two methods. Linear regression and correlation play an important part in the interpretation of quantitative method comparison studies. ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2008.01709.x
更新日期:2008-04-01 00:00:00
abstract:AIMS OF THE STUDY:Patient comprehension is a critical part of meeting medical ethics standards of informed consent in study designs. The aim of the study was to determine if sufficient literature exists to require clinicians to disclose the specific risk that COVID-19 vaccines could worsen disease upon exposure to chal...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13795
更新日期:2020-10-28 00:00:00
abstract:BACKGROUND:Although many models have been developed to explain health behaviour, differences in individual response to symptoms remain largely unexplained; moreover, they tend to underestimate affective (i.e., emotional) processes and they neglect the construct of well-being, despite its predominant role in the definit...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02183.x
更新日期:2009-10-01 00:00:00
abstract::The UK National Health Service (NHS) currently spends in excess of £250 million per annum on angiotensin II receptor blockers (ARBs) for the treatment of hypertension and heart failure; with candesartan currently dominating the market. With the recent introduction of generic losartan, we set out to directly compare th...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1742-1241.2011.02633.x
更新日期:2011-03-01 00:00:00
abstract:AIM:Risk stratification in acute coronary syndrome without ST-segment elevation (NSTE-ACS) and troponin-negative remains a challenge. We evaluated the value of interleukin-6 (IL-6) and amino-terminal pro-B-type natriuretic peptide (NT-proBNP) in the prognosis assessment of low-moderate risk NSTE-ACS and troponin-negati...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12245
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:We aimed to compare the efficacy of silodosin and a terpene combination in the treatment of distal ureteral stones. METHODOLOGY:The data of the patients admitted to the urology policlinic with renal colic, diagnosed with distal ureteral stones, and followed up with medical expulsive therapy between December ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13866
更新日期:2020-11-24 00:00:00
abstract:BACKGROUND:The relationship between psoriasis and cardiomyopathy is understudied in Indian patients. OBJECTIVE:We evaluated psoriasis patients for cardiomyopathy and other echocardiographic abnormalities. METHODS:About 98 (M:F = 67:31) patients with mild to moderate psoriasis aged 18-75 years (mean ± SD = 42.12 ± 12....
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13756
更新日期:2020-10-16 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Persistence with antimuscarinic (AM) drugs prescribed for overactive bladder (OAB) is poor. This study aimed to compare persistence and adherence with the beta-3-adrenoceptor agonist mirabegron (MIR) vs AMs over 12 months. PATIENTS AND METHODS:This retrospective cohort analysis included pat...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12996
更新日期:2017-10-01 00:00:00
abstract::The aim of this review was to outline current forms of surgical simulation and methods of assessing technical skills using these forms of simulation. To review this subject, a literature search was done using key words 'assessment', 'simulation', 'surgery', 'technical skills' and 'virtual reality'. Simulation in surge...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2007.01435.x
更新日期:2007-12-01 00:00:00
abstract::This randomised, double-blind study compared the anti-hypertensive efficacy and tolerability of Candesartan cilexetil (CC 8-16 mg) and Amlodipine (AML 5-10 mg) on home blood pressure (HBP) measurements in mild-to-moderate hypertensive patients. After a 2-week wash-out, patients aged 18-74 years, with a sitting diastol...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1742-1241.2005.00296.x
更新日期:2005-01-01 00:00:00
abstract::This double-blind, randomised, controlled study compared the efficacy of candesartan cilexetil 8 mg (n = 87) and losartan 50 mg (n = 89), once daily for 6 weeks, relative to placebo (n = 80) in patients with mild-to-moderate essential hypertension (diastolic blood pressure (DBP): 95-115 mmHg). Ambulatory BP measuremen...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1368-5031.2006.00903.x
更新日期:2006-04-01 00:00:00
abstract::In a five-year retrospective data analysis, incidence of > stage II necrotising enterocolitis (NEC) was four times higher in aboriginal (18/125) than non-aboriginal (11/306) neonates, all < or = 32 weeks' gestation. Stage III NEC occurred more frequently (10/18 vs 3/11) and related mortality was higher (44.4% vs 0%) i...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:AIMS:The aim of this study was to describe and compare treatment modifications and discontinuation, adherence levels and response to treatment in patients with type 2 diabetes initiating on low-dose vs. standard-dose statin treatment. METHODS:A 2-year follow-up cohort study was performed using data from the Groningen ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12806
更新日期:2016-06-01 00:00:00
abstract:AIMS:We prospectively enrolled 207 patients (121 were 75 or older and 86 younger than 75) who were admitted to three Respiratory Monitoring Units. The primary outcomes were intubation and mortality rates; the secondary outcomes were changes in arterial blood gases analysis, non-invasive ventilation (NIV) duration and l...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12484
更新日期:2014-12-01 00:00:00
abstract::It is important for primary care physicians to recognise rheumatoid arthritis and systemic lupus erythematosus patients as high-risk groups for atherosclerosis, requiring aggressive risk-factor modification. Recent studies suggest that this increased risk is not explained by an excess of traditional risk factors, but ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2005.00489.x
更新日期:2005-07-01 00:00:00