Switching between GLP-1 receptor agonists in clinical practice: Expert consensus and practical guidance.

abstract：AIMS:This was a post hoc analysis to determine whether baseline severity of depression influenced the efficacy of duloxetine in treating major depressive disorder (MDD) and to better characterise the symptom response profile for duloxetine in patients with mild, moderate or more severe depression. METHODS:Data were po...

journal_title：International journal of clinical practice

authors： Shelton RC,Prakash A,Mallinckrodt CH,Wohlreich MM,Raskin J,Robinson MJ,Detke MJ

更新日期：2007-08-01 00:00:00

abstract：:Biochemical test abnormality can indicate chronic alcohol abuse with good clinical sensitivity and specificity. Serum gamma glutamyltransferase and carbohydrate-deficient transferrin are the tests most frequently abnormal. ...

journal_title：International journal of clinical practice

authors： Rosalki SB

更新日期：1999-03-01 00:00:00

abstract：AIMS:Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out 6 years earli...

journal_title：International journal of clinical practice

authors： Molero JM,Moragas A,González López-Valcárcel B,Bjerrum L,Cots JM,Llor C

更新日期：2019-05-01 00:00:00

abstract：:A 39-year-old entertainer was referred in November 2000 for suspected secondary hypothroidism found during a routine insurance check. Thyroid stimulating hormone (TSH) was 0.30 mIU/L (NR 0.47-4.68 mIU/L) and total T4 was 21.6 nmol/l (NR 57.9-154.4 nmol/l). She had enjoyed good past health and gave birth to a baby girl...

journal_title：International journal of clinical practice

authors： Chan WB,Chow CC,Cockram CS

更新日期：2004-10-01 00:00:00

abstract：:To investigate the influence of the S447X variant in lipoprotein lipase (LPL) gene on the response rate to therapy with the thiazolidinedione pioglitazone. A total of 113 diabetic patients were treated with pioglitazone 30 mg for 10 weeks. Response to the pioglitazone treatment was defined by either a >10% relative re...

journal_title：International journal of clinical practice

authors： Wang G,Wang X,Zhang Q,Ma Z

更新日期：2007-04-01 00:00:00

abstract：:Despite huge advances in terms of the impact of antiretroviral therapy on HIV-related morbidity and mortality patients continue to fail therapy. We discuss the reasons why failure occurs including primary or transmitted resistance, poor adherence, toxicity and drug potency. We performed a review of PubMed, Medline and...

journal_title：International journal of clinical practice

authors： Waters L,Nelson M

更新日期：2007-06-01 00:00:00

abstract：:With increasing personal access to the internet, and the mass of medical information available in cyberspace, many patients may access information before an outpatient consultation. Since this information may shape individual health beliefs and expectations, yet is acknowledged to be of very variable quality, it may b...

journal_title：International journal of clinical practice

authors： Larner AJ

更新日期：2002-04-01 00:00:00

abstract：:The purpose of this survey was to ascertain which physiotherapy techniques are currently used, how interventions are assessed and to determine the views of physiotherapists in the UK on the need for further research. Senior physiotherapists in 100 randomly selected hospitals providing respiratory care in the UK were s...

journal_title：International journal of clinical practice

authors： O'Neill B,Bradley JM,McArdle N,MacMahon J

更新日期：2002-01-01 00:00:00

abstract：:Helicobacter pylori infection is one of the most prevalent infections in humans. The high prevalence and the association with peptic ulceration and gastric cancer require simple and non-invasive methods for the diagnosis of the infection. Detection of salivary anti-H. pylori IgG antibodies has advantages compared with...

journal_title：International journal of clinical practice

authors： Sönmezoglu M,Baysal B,Ergen A,Barut SG

更新日期：2005-04-01 00:00:00

abstract：:Patients presenting to the emergency department with chest pain are evaluated by emergency physicians in hospitals without cardiology cover 24 h a day. The purpose of this study is to determine the consistency of electrocardiography (ECG) interpretation and chest pain likelihood classification between emergency physic...

journal_title：International journal of clinical practice

authors： Eken C,Goksu E,Eray O,Yalcinkaya S

更新日期：2006-10-01 00:00:00

abstract：:This trial assessed whether a simple clinical tool can be used to stratify patients with diabetes, according to risk of developing foot ulceration. This was a prospective, observational follow-up study of 3526 patients with diabetes (91% type 2 diabetes) attending for routine diabetes care. Mean age was 64.7 (range 15...

journal_title：International journal of clinical practice

authors： Leese GP,Reid F,Green V,McAlpine R,Cunningham S,Emslie-Smith AM,Morris AD,McMurray B,Connacher AC

更新日期：2006-05-01 00:00:00

abstract：AIMS:Prominent anxiety symptoms are related to poor clinical course and outcome in major depressive disorder (MDD). The aim of this randomised, open-label, controlled study is to compare the efficacy and tolerability of mirtazapine in the form of orally disintegrating tablets against paroxetine in treating MDD patients...

journal_title：International journal of clinical practice

authors： Kim JE,Yoon SJ,Kim J,Jung JY,Jeong HS,Cho HB,Shin E,Lyoo IK,Kim TS

更新日期：2011-03-01 00:00:00

abstract：:Monomeric prolactin (PRL) of molecular weight 23 kDa constitutes up to 95% of adult serum PRL. Macroprolactin is a large antigen-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating PRL. Thus, in most cases, hyperprolactinaemia is usually a result of high levels of mono...

journal_title：International journal of clinical practice

authors： Sadideen H,Swaminathan R

更新日期：2006-04-01 00:00:00

abstract：:Gas explosion during diathermy gastrotomy is a very rare occurrence. We report on an unusual case of gas explosion during diathermy gastrotomy in a patient with carcinoma of the gastric antrum. ...

journal_title：International journal of clinical practice

authors： Inan A,Dener C,Demirci S

更新日期：2003-10-01 00:00:00

abstract：:This study was to evaluate the efficacy and safety of ibutilide and propafenone given intravenously in converting recent onset atrial fibrillation (AF). Eighty-two consecutive patients with AF (onset in 2 h to 90 days) were randomly assigned to receive two 10-min infusions, 10 min apart, of either ibutilide (1 mg) or ...

journal_title：International journal of clinical practice

authors： Zhang N,Guo JH,Zhang HCh,Li XB,Zhang P,Xn Y

更新日期：2005-12-01 00:00:00

abstract：:Pharmacological treatment of hypertension represents a cost-effective way for preventing cardiovascular and renal complications. To benefit maximally from antihypertensive treatment blood pressure (BP) should be brought to below 140/90 mmHg in every hypertensive patient, and even lower (< 130/80 mmHg) if diabetes or r...

journal_title：International journal of clinical practice

authors： Struijker-Boudier HA,Ambrosioni E,Holzgreve H,Laurent S,Mancia G,Ruilope LM,Waeber B

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:The association between testosterone deficiency and insulin resistance in men with type 2 diabetes is well established. Current Endocrine Society and European Association of Urology guidelines recommend the measurement of testosterone levels in all men with type 2 diabetes and in men suffering from erectile ...

journal_title：International journal of clinical practice

authors： Hackett G,Cole N,Bhartia M,Kennedy D,Raju J,Wilkinson P,Saghir A,Blast Study Group.

更新日期：2014-02-01 00:00:00

abstract：:Hormone replacement therapy (HRT) leads to a similar annual increase in risk of breast cancer as does each extra year of remaining premenopausal. Taken for more than 10 years HRT leads to a 35% increase in risk of developing breast cancer. It does not increase a woman's risk of dying of breast cancer, and may improve ...

journal_title：International journal of clinical practice

authors： Faiz O,Fentiman IS

更新日期：1998-03-01 00:00:00

abstract：:After more than 20 years, the conflict of interest (COI) movement has failed to substantiate its central claim that interactions between physicians, researchers and the medical products industry cause physicians to make clinical decisions that are adverse to the best interests of their patients. The COI movement's ins...

journal_title：International journal of clinical practice

authors： Hong PS,Sulke AN,Yousef ZR

更新日期：2014-06-01 00:00:00

abstract：AIMS:Little is known on factors associated with switching and combination use of antidepressants. Our aim was to describe such use and to analyse the association with socioeconomic factors and level of care in Swedish adults aged 20-34 years. METHODS:Individuals, aged 20-34 years, who purchased an antidepressant in Ja...

journal_title：International journal of clinical practice

authors： Andersson Sundell K,Petzold MG,Wallerstedt SM

更新日期：2013-12-01 00:00:00

abstract：:Overactivity of the renin-angiotensin-aldosterone system (RAAS) plays a key role in the pathophysiology of heart failure (HF) and chronic kidney disease (CKD). RAAS antagonists can significantly improve clinical outcomes, but monotherapy blocks but one step of the RAAS and can be bypassed through compensatory mechanis...

journal_title：International journal of clinical practice

authors： Ziff OJ,Covic A,Goldsmith D

更新日期：2016-07-01 00:00:00

abstract：:Graham Jackson introduced the concept that erectile dysfunction was a marker for undiagnosed cardiovascular disease and future events. Unfortunately this had had modest impact on CVD management as ED is not incorporated into current risk calculators. In this paper, we examine recent evidence as to whether ED should be...

journal_title：International journal of clinical practice

authors： Hackett G,Kirby M

更新日期：2018-02-01 00:00:00

abstract：:Tumours of the perianal region and anal canal are uncommon and can present in a variety of ways. Acute anorectal sepsis is a common condition that usually presents as a painful lump close to the anal margin. Tumours in the perianal region may mimic the symptoms and signs of anorectal sepsis, thereby leading to a delay...

journal_title：International journal of clinical practice

authors： Bracey EE,Mathur P,Dooldeniya M,Joshi A,Dawson PM

更新日期：2003-05-01 00:00:00

abstract：:Men with cardiovascular disease (CVD) are more likely to have erectile dysfunction (ED) than the general population, as both conditions share risk factors and some drugs used to treat CVD may induce ED as a side-effect. This study was undertaken to assess the efficacy and safety of sildenafil citrate for the treatment...

journal_title：International journal of clinical practice

authors： Olsson AM,Persson CA,Swedish Sildenafil Investigators Group.

更新日期：2001-04-01 00:00:00

abstract：:Over the past years, there has been an explosive increase in the prevalence of type 2 diabetes (T2DM) and this is expected to continue, entailing associated morbidity and mortality. An increasing number of studies explore the different ways T2DM could be prevented. On-going lifestyle modifications need to be addressed...

journal_title：International journal of clinical practice

authors： Gruber A,Nasser K,Smith R,Sharma JC,Thomson GA

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:Malnutrition is a crucial health problem predominantly in the developing countries. Malnutrition in children is one of the main risk factors for diseases and mortality. Club foot or congenital talipes equinovarus (CTEV) is the most common form of congenital orthopaedic abnormality. Over the past 20 years, th...

journal_title：International journal of clinical practice

authors： Muzzammil M,Mughal A,Qadir A,Mughal A,Effendi J,Bhatti A,Minhas MS

更新日期：2020-12-20 00:00:00

abstract：AIM:Splenectomised patients are associated with lifelong risk of fatal overwhelming post-splenectomy infection (OPSI), which is mostly caused by Streptococcus pneumoniae. Today OPSI cases can still be reported even in patients with appropriate vaccination. In our study, the levels of vaccine-specific memory B- and T ce...

journal_title：International journal of clinical practice

authors： Gazi U,Karasartova D,Sahiner IT,Gureser AS,Tosun O,Derici MK,Dolapci M,Taylan Ozkan A

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Overactive bladder (OAB) syndrome has a diverse etiology that disrupts quality of life domains in affected patients. OAB is significantly under-recognised and undertreated, especially in the primary care setting. In order to educate primary care providers about OAB recognition, evaluation and management, we ...

journal_title：International journal of clinical practice

authors： Turell W,Howson A,MacDiarmid SA,Rosenberg MT

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Mobile smart phones have become increasingly integrated into the practice of doctors and allied medical professionals. Recent studies suggest them to represent reservoirs for pathogens with potential to cause nosocomial infections. This study aimed to investigate the level of contamination on phones used on ...

journal_title：International journal of clinical practice

authors： Mark D,Leonard C,Breen H,Graydon R,O'Gorman C,Kirk S

更新日期：2014-09-01 00:00:00

abstract：:Linear regression methods try to determine the best linear relationship between data points while correlation coefficients assess the association (as opposed to agreement) between the two methods. Linear regression and correlation play an important part in the interpretation of quantitative method comparison studies. ...

journal_title：International journal of clinical practice

authors： Twomey PJ,Kroll MH

更新日期：2008-04-01 00:00:00