Patterns of depressive symptom response in duloxetine-treated outpatients with mild, moderate or more severe depression.

Abstract:

AIMS:This was a post hoc analysis to determine whether baseline severity of depression influenced the efficacy of duloxetine in treating major depressive disorder (MDD) and to better characterise the symptom response profile for duloxetine in patients with mild, moderate or more severe depression. METHODS:Data were pooled from four double-blind, placebo-controlled studies in which outpatients with MDD were randomised to duloxetine (60 mg/day) or placebo for 8-9 weeks. Patients were retrospectively stratified according to baseline 17-item Hamilton Depression Rating scale (HAMD17) total scores: mild=total score

journal_name

Int J Clin Pract

authors

Shelton RC,Prakash A,Mallinckrodt CH,Wohlreich MM,Raskin J,Robinson MJ,Detke MJ

doi

10.1111/j.1742-1241.2007.01444.x

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

1337-48

issue

8

eissn

1368-5031

issn

1742-1241

pii

IJCP1444

journal_volume

61

pub_type

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