Abstract：
AIMS:The impact of ongoing PCR positivity on COVID-19 patients and the strategy and period of isolation were not fully understood. We aimed to investigate the factors that cause prolonged PCR positivity and its clinical impact on COVID-19 infection. In addition, we searched for an answer on what length of time would be best for isolation. METHODS:Patients with confirmed COVID-19 infection were included in this retrospective study. Patients with PCR positivity (after symptom onset) longer than 14 days and PCR positivity less than 14 days were compared. The relationship between duration of symptoms and PCR negation time was examined. RESULTS:A total of 339 patients were included in this study. Fifty (14%) patients had prolonged PCR positivity after 14 days. Demographic and clinical features, and clinical outcomes (disease severity and mortality) were similar among the two groups. Age (p 0.035) and symptom duration at admission (P < .001) were found as independent factors for prolonged PCR positivity. Median of total symptom duration was 7 days (IQR: 5-11). The duration of negative conversion of PCR test was median 9 days (IQR: 7-12) after symptom onset and PCR tests became negative 3 days (IQR: 2-5) after symptom improvement. CONCLUSIONS:We found that ongoing PCR positivity has no detrimental effect on the course of the disease and clinical outcomes in COVID-19 patients. In addition, our results showed that isolation may be discontinued 10-14 days after symptom onset and/or after 2-5 days after resolution of symptoms. This results also support WHO and ECDC recommendations on this matter.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Eser F,Kayaaslan B,Güner R,Hasanoğlu I,Kaya Kalem A,Aypak A,Akinci Edoi
10.1111/ijcp.14025subject
Has Abstractpub_date
2021-01-15 00:00:00pages
e14025eissn
1368-5031issn
1742-1241pub_type
杂志文章abstract：AIMS:To examine whether the blood pressure (BP) profiles of lumiracoxib and high-dose ibuprofen differed in patients treated with different classes of antihypertensive medications. METHODS:A 4-week, multicentre, randomised, double-blind study has compared the effects of lumiracoxib 100 mg once daily (od) (n = 394) and...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1742-1241.2010.02346.x
更新日期：2010-05-01 00:00:00
abstract：AIMS:The aim of this study was to assess patient characteristics, medication treatment patterns and healthcare resource utilization among men with existing erectile dysfunction (ED) or benign prostatic hyperplasia (BPH), who are newly diagnosed with the second condition (BPH or ED) compared with those with only one con...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12657
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:Maternal responsiveness seems to be necessary for a child to develop a safe attachment. However, even after many years of research on maternal responsiveness, only a few attempts have been made to find ways of promoting mother and child interaction. This study aimed at determining the association between mat...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.14043
更新日期：2021-01-23 00:00:00
abstract：:The management approach to non-insulin-dependent diabetes mellitus among family doctors in Hong Kong was studied using two case histories. In 1996, all 804 fellows, members and associate members of the Hong Kong College of Family Physicians were sent a letter and a questionnaire. Of the 512 who responded, 405 were mal...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：OBJECTIVE:We aimed to evaluate the use of computed tomography (CT) as the first imaging modality in patients with renal colic and microscopic haematuria. METHODOLOGY:The patients that presented to the emergency service of six health centers with renal colic between January 2017 and January 2018 and were found to have ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13826
更新日期：2020-11-09 00:00:00
abstract：OBJECTIVES:To test whether parathyroid hormone (PTH) might be related to the development of atherosclerosis in postmenopausal women, we measured serum levels of PTH, the carotid intima-media thickness (IMT), and other clinical and biochemical parameters. METHODS:One hundred and seven postmenopausal women were recruite...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2008.01801.x
更新日期：2008-09-01 00:00:00
abstract：:Buprenorphine is a semi-synthetic opioid derived from thebaine. The transdermal formulation of buprenorphine has been available in Belgium for 3 years, during which time the Pain Clinic of the St Elisabeth of Verviers Hospital has gained experience in the use of transdermal buprenorphine for the treatment of moderate-...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.01109.x
更新日期：2006-10-01 00:00:00
abstract：:Spontaneous tumour lysis syndrome (STLS) inducing acute uric acid nephropathy, a rare and neglected disease, presents more insidiously than conventional post-treatment tumour lysis syndrome. Although STLS is a serious and potentially fatal complication in patients with neoplastic disorders, few investigations have add...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：:Fluid in the pleural space is a common sequela of a wide range of diseases which may be pulmonary, pleural or extrapulmonary. As the differential diagnosis is wide, a systematic approach to investigation and diagnosis is recommended. This review highlights the important features and recommendations for the investigati...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2009.02068.x
更新日期：2009-11-01 00:00:00
abstract：:Randomised controlled trials evaluating the effect of statin use on maintenance of normal sinus rhythm (NSR) after electrical cardioversion (ECV) of persistent atrial fibrillation (AF) have demonstrated conflicting results. However, many of these trials were of relatively small size and thus underpowered to adequately...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1742-1241.2010.02387.x
更新日期：2010-07-01 00:00:00
abstract：:Patients with groin herniae do not always seek medical advice and, when listed for surgery, often wait many months for elective repair. We audited our emergency admissions for complicated groin herniae to establish whether a change in policy for elective surgery could lower their incidence. We performed a retrospectiv...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1368-5031.2004.0097.x
更新日期：2004-02-01 00:00:00
abstract：:Wiley has updated its publishing ethics guidelines, first published in 2006. The new guidelines provide guidance, resources and practical advice on ethical concerns that arise in academic publishing for editors, authors and researchers, among other audiences. New guidance is also included on whistle blowers, animal re...
journal_title：International journal of clinical practice
pub_type： 信件
doi：10.1111/ijcp.12557
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Ultrasonography is increasingly used by clinicians to identify abdominal aortic aneurysms (AAA). We performed a systematic review and meta-analysis comparing the accuracy of non-radiologist performed ultrasound (NRPUS) for AAA disease to the 'gold standard' of radiologist performed aortic imaging (RPI), intr...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/ijcp.12453
更新日期：2014-09-01 00:00:00
abstract：AIMS:The association between inhaled corticosteroid (ICS) use and pulmonary tuberculosis (TB) development is uncertain. We conducted a population-based case-control study to investigate whether ICS use increases the risk of developing TB. METHODS:Tuberculosis patients aged 18 years and older were identified using the ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12459
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Elevated levels of blood lipids are considered a major modifiable risk factor for the development of cardiovascular diseases. The optimal management of dyslipidaemia remains inadequate worldwide. Accordingly, there is an increasing need to evaluate the basis that health care providers are using to control dy...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13784
更新日期：2020-10-23 00:00:00
abstract：:Ezetimibe/simvastatin (INEGY), a dual inhibitor of both cholesterol production and absorption, is a new approach to the management of hyperlipidaemia. Recent studies have shown that it produces greater reductions in low-density lipoprotein (LDL) cholesterol than the single inhibition of statin therapy, enabling many m...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2005.00737.x
更新日期：2005-12-01 00:00:00
abstract：AIMS:Studies on macrovascular consequences of glucose control in elderly patients (>75 years) with type 2 diabetes mellitus (T2DM) are lacking. The present study aimed to investigate the relationship between HbA(1c) and mortality in this specific population. METHODS:Between 1998 and 1999, 374 primary care patients wit...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2010.02596.x
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Antibiotics are widely used and inaccurate or inappropriate prescription of antibiotics causes a significant increase in the prevalence of multidrug-resistant bacterial infections among children. This research aimed to study antibiotic prescriptions in hospitalised paediatric patients and to determine the pr...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13782
更新日期：2020-10-24 00:00:00
abstract：:Fracture of the penis can be managed conservatively or surgically. Conservative management is associated with a high morbidity, and early surgical repair of the fracture is usually recommended in order to prevent complications. Because a fractured penis is swollen throughout its length, it is difficult to identify the...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Mobile smart phones have become increasingly integrated into the practice of doctors and allied medical professionals. Recent studies suggest them to represent reservoirs for pathogens with potential to cause nosocomial infections. This study aimed to investigate the level of contamination on phones used on ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12448
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Alternatives to acute hospital admission are required to accommodate the increasing pressures on health services. Since physiotherapists and occupational therapists are integral to inpatient teams, they may also be integral to admission replacement services, and thus their roles in these services merit inves...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13462
更新日期：2020-06-01 00:00:00
abstract：:Calcium dobesilate (Doxium) is used in the treatment of diabetic retinopathy. Clinical studies show a slowdown of the progression of the disease after long-term oral treatment. The main action of the drug is related to a reduction of microvascular permeability as measured by different parameters and methods (vitreous ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:Urinary tract infections (UTI) and asymptomatic bacteriuria (AB) during pregnancy can result in considerable maternal and foetal adverse outcomes. Production of extended-spectrum beta-lactamase (ESBL) is a major antibiotic resistance mechanism by Enterobacteriaceae. OBJECTIVES:To determine the global preval...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13422
更新日期：2019-09-18 00:00:00
abstract：AIM:To assess attitudes and beliefs towards benign prostatic hyperplasia (BPH)/ lower urinary tract symptoms (LUTS) and its treatment among patients and physicians in Latin America, Asia Pacific and the Commonwealth of Independent States (CIS). METHODS:Cross-sectional, quantitative study conducted between December 201...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/ijcp.12879
更新日期：2016-10-01 00:00:00
abstract：:Erectile Dysfunction (ED) is common in men with diabetes. Diabetic men are three times as likely to develop ED as non-diabetic men. The cause is multifactorial, but most commonly reflects endothelial dysfunction and autonomic neuropathy. Diabetes and vascular disease often coexist and ED may be a marker for silent occ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2004.00180.x
更新日期：2004-04-01 00:00:00
abstract：:High plasminogen activator inhibitor-1 (PAI-1) levels are potential risk factors for cardiovascular disease. The risk profile of white coat hypertension (WCHT) has not yet been completely clear. In this study, we aimed to determine the plasma levels of PAI-1, markers of fibrinolysis and increased cardiovascular diseas...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1368-5031.2004.00119.x
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:Substantial residual cardiovascular risk persists despite effective LDL lowering treatment in populations at elevated risk for adverse cardiovascular outcomes. Low HDL cholesterol is an independent cardiovascular risk factor and occurs in about one-third of patients treated for dyslipidaemia in Europe. Moreo...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01514.x
更新日期：2007-11-01 00:00:00
abstract：AIMS:The IMPROVE observational study evaluated the safety profile and effectiveness of biphasic insulin aspart 30/70 (BIAsp 30) in patients with type 2 diabetes in routine practice in 11 countries. METHODS:Patients who initiated insulin therapy with, or switched existing insulin therapy to, BIAsp 30 in routine care we...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.1742-1241.2009.02002.x
更新日期：2009-03-01 00:00:00
abstract：:Hepatic endometriosis is extremely rare. The diagnosis is often missed and treatment is delayed. A 37-year-old woman was referred to the gynaecology department with vague abdominal pains. She had a past history of pelvic endometriosis and hysterectomy with bilateral salpingo-oophorectomy. Further investigations in due...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：AIMS:The main objective of this study was to see whether diabetes is associated with an increased collision risk and to test the effect of age and gender on the overall collision risk for diabetes drivers. MATERIALS AND METHODS:Twenty-eight studies were included in meta-analysis, using mean age, gender, continent and ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析
doi：10.1111/ijcp.12832
更新日期：2016-07-01 00:00:00
