Abstract：
OBJECTIVES:To test whether parathyroid hormone (PTH) might be related to the development of atherosclerosis in postmenopausal women, we measured serum levels of PTH, the carotid intima-media thickness (IMT), and other clinical and biochemical parameters. METHODS:One hundred and seven postmenopausal women were recruited for this study. The serum level of PTH was measured by immunoradiometric assay, and carotid IMT was measured with high resolution B-mode ultrasonography. RESULTS:On the basis of bivariate correlation analyses or unpaired t-tests, the body mass index (BMI), waist circumference, estimated glomerular filtration rate, and 25-hydroxyvitamin D were not associated with carotid IMT. In contrast, age (r = 0.414, p < 0.001), serum level of PTH (r = 0.304, p = 0.001), hypertension (p < 0.001), and hypercholesterolaemia (p = 0.004) were related to carotid IMT. On the basis of multiple regression analysis, the serum level of PTH (beta = 0.198, p = 0.029), as well as age (beta = 0.309, p = 0.001) and hypertension (beta = 0.262, p = 0.006), were independent predictors of carotid IMT. CONCLUSIONS:Our results have demonstrated that serum PTH is an independent determinant of carotid IMT in postmenopausal women. This result suggests that serum PTH, even in the reference range, might be associated with the development of atherosclerosis or cardiovascular diseases in postmenopausal women. Further study is necessary in males and premenopausal women to fully elucidate the clinical significance of this finding.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Choi HS,Kim SH,Rhee Y,Cho MA,Lee EJ,Lim SKdoi
10.1111/j.1742-1241.2008.01801.xsubject
Has Abstractpub_date
2008-09-01 00:00:00pages
1352-7issue
9eissn
1368-5031issn
1742-1241pii
IJCP1801journal_volume
62pub_type
杂志文章abstract：BACKGROUND:Although many models have been developed to explain health behaviour, differences in individual response to symptoms remain largely unexplained; moreover, they tend to underestimate affective (i.e., emotional) processes and they neglect the construct of well-being, despite its predominant role in the definit...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2009.02183.x
更新日期：2009-10-01 00:00:00
abstract：:Hypercalcemia can be an uncommon manifestation of various infections and malignancies in HIV-positive patients. A case of severe symptomatic hypercalcemia as the first sign of non-Hodgkin's lymphoma in a patient found later to be HIV positive is presented. Differential diagnosis of calcium disorders should include tes...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2004.00055.x
更新日期：2004-11-01 00:00:00
abstract：:Lithium salts have been used in medicine for over a century and are a widely accepted treatment. Clinical practice in the London borough of Barnet led us to suspect that agreed guidelines were not being followed. We checked them against published guidelines and followed up their implementation. A list of patients on l...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:The objectives of this study were to compare the performance indicators of risk-adjustment models based on administrative and clinical data in Korea, and to assess whether administrative data alone is useful for comparing quality of care. METHODS:Outcome was defined as death within 30 days of discharge. For ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1742-1241.2007.01345.x
更新日期：2007-07-01 00:00:00
abstract：:The purpose of this survey was to ascertain which physiotherapy techniques are currently used, how interventions are assessed and to determine the views of physiotherapists in the UK on the need for further research. Senior physiotherapists in 100 randomly selected hospitals providing respiratory care in the UK were s...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:The misery of living with atopic eczema (syn. dermatitis, AD) cannot be overstated for it may have a profoundly negative effect on the health-related quality of life (HRQoL) of children and their family unit in many cases. As it is one of the commonest chronic relapsing childhood dermatosis (UK lifetime prevalence 16-...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2006.01047.x
更新日期：2006-08-01 00:00:00
abstract：:Non-small cell lung cancer (NSCLC) is the most lethal of the common solid malignancies. It is predominantly a disease of the elderly with the median age at diagnosis 68 years. Unfortunately, the majority of patients present with advanced disease whereby palliation is the primary aim of treatment. The elderly have a lo...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2005.00795.x
更新日期：2006-03-01 00:00:00
abstract：OBJECTIVE:Few published studies have examined survival rates for patients with metastatic colorectal cancer (mCRC) by number of lines of treatment received or stage at diagnosis. This study aims to evaluate survival and numbers of lines of treatment in USA mCRC managed care patients. METHODS:To evaluate the impact of ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12543
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:This review examines the available data on the efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) for treating the commonly missed climacteric symptoms of menopause. DISCUSSION:Although some women may pass through the menopausal transition phas...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01566.x
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVES:In late July, Cyprus experienced the second epidemic wave of COVID-19. We present the steps taken by the government and evaluate their effect on epidemic trends. MATERIALS:Cyprus Press and Information Office data were analysed. Using an R-based forecasting program, two models were created to predict cases u...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13944
更新日期：2020-12-18 00:00:00
abstract：INTRODUCTION AND PURPOSE:The need for aggressive efforts to help tobacco users quit remains a healthcare priority. Brief interventions delivered in the healthcare environment continue to be a valuable component of a comprehensive tobacco control policy. Unfortunately, such treatments are offered less often than desired...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12386
更新日期：2014-07-01 00:00:00
abstract：:The potential effect of orlistat on cardiovascular co-morbidities may have been previously underestimated. This study assesses the efficacy of orlistat therapy for weight loss and cardiovascular risk factor reduction in obese patients with cardiovascular risk. This was a 54-week, double-blind, randomised, placebo-cont...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2002-09-01 00:00:00
abstract：:This open multicentre study compared the efficacy and tolerability of clarithromycin and spiramycin in the treatment of lower respiratory tract infections in Brazil and Colombia. A total of 125 patients with a clinical and radiological diagnosis of pneumonia, acute bronchitis or exacerbation of chronic bronchitis were...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1999-09-01 00:00:00
abstract：:Despite potential benefits, primary care clinicians may avoid using antimuscarinics in men with overactive bladder (OAB) symptoms because of safety concerns. To review the efficacy and safety of antimuscarinics, alone or in combination with an α-blocker, for the treatment of men with OAB symptoms, we conducted a syste...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2010.02611.x
更新日期：2011-04-01 00:00:00
abstract：:Erectile Dysfunction (ED) is common in men with diabetes. Diabetic men are three times as likely to develop ED as non-diabetic men. The cause is multifactorial, but most commonly reflects endothelial dysfunction and autonomic neuropathy. Diabetes and vascular disease often coexist and ED may be a marker for silent occ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2004.00180.x
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND:The decision on whether or not to treat a first seizure is dependent on several medical and non-medical factors. AIMS:In this review, we have summarised the important aspects that determine the advantages and disadvantages of treating a first seizure. We have looked at evidence from randomised controlled tr...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2008.01896.x
更新日期：2008-12-01 00:00:00
abstract：:Buprenorphine is a semi-synthetic opioid derived from thebaine. The transdermal formulation of buprenorphine has been available in Belgium for 3 years, during which time the Pain Clinic of the St Elisabeth of Verviers Hospital has gained experience in the use of transdermal buprenorphine for the treatment of moderate-...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.01109.x
更新日期：2006-10-01 00:00:00
abstract：:Amyloidosis commonly involves the liver but clinical features of liver disease are rare. We report a case of cholestasis and hepatic failure in an 85-year-old man due to primary amyloidosis. This has not been reported previously in anyone of this advanced age. We discuss the clinical features of hepatic amyloidosis an...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:Over the past years, there has been an explosive increase in the prevalence of type 2 diabetes (T2DM) and this is expected to continue, entailing associated morbidity and mortality. An increasing number of studies explore the different ways T2DM could be prevented. On-going lifestyle modifications need to be addressed...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2006.00929.x
更新日期：2006-05-01 00:00:00
abstract：AIMS:Our goal was to determine the effect of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) consensus algorithm for the initiation and adjustment of type 2 diabetes (T2D) therapy, published in 2006, on the incidence of early metformin monotherapy (EMM), defined as ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2009.02319.x
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:In the setting of an increasing workload for radiologists, this study focuses on the feasibility of skill mixing in breast imaging in a hospital radiology department. METHODS:Two radiological technologists with more than 10 years of experience in performing mammograms were trained in prereading mammograms to s...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2009.02310.x
更新日期：2010-03-01 00:00:00
abstract：:Despite efforts to diagnose and treat hypertension effectively, the goal of lowering blood pressure (BP) levels is rarely achieved, as treatment is often initiated with a single antihypertensive agent. The aim of this study was to assess the safety and efficacy of a first-line fixed-dose combination treatment compared...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1368-5031.2006.00841.x
更新日期：2006-03-01 00:00:00
abstract：AIM:To raise awareness on nocturia disease burden and to provide simplified aetiologic evaluation and related treatment pathways. METHODS:A multidisciplinary group of nocturia experts developed practical advice and recommendations based on the best available evidence supplemented by their own experiences. RESULTS:Noc...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/ijcp.13027
更新日期：2017-11-01 00:00:00
abstract：:To investigate ethnic differences and the effect of age and education on awareness and attitudes of women towards hormone replacement therapy (HRT), we conducted a questionnaire survey of 180 women attending a gynaecology clinic, of whom 152 (84.4%) responded. Seventy-one of the women had heard of HRT. Awareness of HR...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Fracture of the penis can be managed conservatively or surgically. Conservative management is associated with a high morbidity, and early surgical repair of the fracture is usually recommended in order to prevent complications. Because a fractured penis is swollen throughout its length, it is difficult to identify the...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:The Surgical Nutrition Advisory Team (SNAT) of our hospital, formed in October 1992, decided to study the impact of such a team on the six months before and after its formation on catheter care and nutritional support in total parenteral nutrition. Our study showed that with a dedicated nutritional team, catheter seps...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：:Most cases of splenic artery aneurysm are asymptomatic, being found incidentally at the time of investigations (e.g. ultrasound, computed tomography, angiography) or laparotomy for other conditions. Rupture of a splenic artery aneurysm with erosion into the stomach is a rare cause of massive upper gastrointestinal hae...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：BACKGROUND:Plasminogen Activator Inhibitor 1 (PAI-1) is a prothrombotic adipokine involved in the coagulation cascade and fibrinolysis that associated with proinflammatory adipokines may increase the risk related to obesity. Anthropometric measures are commonly used in clinical practice and, currently, neck circumferen...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12041
更新日期：2013-03-01 00:00:00
abstract：:There has been much debate over the past 50 years concerning the association between colorectal carcinoma and inflammatory bowel disease. Until recently, it was widely accepted there was a higher risk in those with widespread ulcerative colitis. However, evidence now suggests an almost equal incidence in those with Cr...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：:Tuberculosis is an uncommon cause of carpal tunnel syndrome. We report a patient with systemic lupus erythematosus who developed hand numbness. Ultrasonic, operative and microbiological findings supported the diagnosis of median nerve compression secondary to a tuberculous abscess. The symptoms resolved with surgical ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
