Diabetes prevention: is there more to it than lifestyle changes?

abstract：BACKGROUND:Sleep-disordered breathing (SDB) is common in heart failure patients. Many of them still remain undiagnosed. The aim of this study was to detect clinical predictors of sleep apnoea which may help to identify patients with SDB at a heart failure clinic. METHODS:We performed an in-home sleep study on 115 cons...

journal_title：International journal of clinical practice

authors： Herrscher TE,Akre H,Overland B,Sandvik L,Westheim AS

更新日期：2014-06-01 00:00:00

abstract：:The potential effect of orlistat on cardiovascular co-morbidities may have been previously underestimated. This study assesses the efficacy of orlistat therapy for weight loss and cardiovascular risk factor reduction in obese patients with cardiovascular risk. This was a 54-week, double-blind, randomised, placebo-cont...

journal_title：International journal of clinical practice

authors： Broom I,Wilding J,Stott P,Myers N,UK Multimorbidity Study Group.

更新日期：2002-09-01 00:00:00

abstract：:The effects of diltiazem treatment on symptoms of chronic anal fissures and their long-term outcome were investigated. One hundred and twelve patients were supplied with 6-week course of 2% diltiazem cream for twice-daily topical application. The medical notes and extended follow-up by telephone for 112 patients were ...

journal_title：International journal of clinical practice

authors： Nash GF,Kapoor K,Saeb-Parsy K,Kunanadam T,Dawson PM

更新日期：2006-11-01 00:00:00

abstract：:Spontaneous tumour lysis syndrome (STLS) inducing acute uric acid nephropathy, a rare and neglected disease, presents more insidiously than conventional post-treatment tumour lysis syndrome. Although STLS is a serious and potentially fatal complication in patients with neoplastic disorders, few investigations have add...

journal_title：International journal of clinical practice

authors： Hsu HH,Chen YC,Tian YC,Chan YL,Kuo MC,Tang CC,Fang JT,Lee SY,Yang CW

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Budesonide/formoterol is an effective treatment for both asthma and chronic obstructive pulmonary disease. This study compared the efficacy and safety of a novel hydrofluoroalkane (HFA) pressurised metered-dose inhaler (pMDI) formulation of budesonide/formoterol with that of budesonide pMDI and budesonide/fo...

journal_title：International journal of clinical practice

authors： Morice AH,Peterson S,Beckman O,Osmanliev D

更新日期：2007-11-01 00:00:00

abstract：:Tonsillectomy is the most commonly performed otolaryngological procedure in most units. There is considerable financial pressure to perform paediatric tonsillectomy as a day case. Responding to concern that day case tonsillectomy might not be welcomed by parents or felt to be in the best interests of the patients, we ...

journal_title：International journal of clinical practice

authors： Vowles R,Loney E,Williams H,Gormley-Fleming E,Kulkarni P,Ryan R

更新日期：2000-05-01 00:00:00

abstract：:The UK National Health Service (NHS) currently spends in excess of £250 million per annum on angiotensin II receptor blockers (ARBs) for the treatment of hypertension and heart failure; with candesartan currently dominating the market. With the recent introduction of generic losartan, we set out to directly compare th...

journal_title：International journal of clinical practice

authors： Grosso AM,Bodalia PN,Macallister RJ,Hingorani AD,Moon JC,Scott MA

更新日期：2011-03-01 00:00:00

abstract：:A case of a child with acute cerebellar ataxia associated with chickenpox virus infection is described. Acute cerebellar ataxia associated with chickenpox is a well-recognised complication and the pertinent features of this condition are discussed. ...

journal_title：International journal of clinical practice

authors： Saab M,Wadhwa V

更新日期：2002-11-01 00:00:00

abstract：:We report a case of acute myocardial infarction in an HIV-infected patient without significant coronary artery disease (CAD) risk factors. The patient underwent rescue percutaneous transluminal coronary angioplasty (PTCA), with a successful outcome. We presume a possible pathogenetic role of anti-retroviral therapy an...

journal_title：International journal of clinical practice

authors： Saporito F,Micari A,Raffa S,Cerrito M,Micari G,Grassi R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Exhaustion is the perception of low energy. Little is known about how exhaustion persists, remits or reappears over time in patients with chronic obstructive pulmonary disease (COPD) or how to predict these events. We determined the likelihood of transitions between states of exhaustion and no ...

journal_title：International journal of clinical practice

authors： Medina-Mirapeix F,Bernabeu-Mora R,Giménez-Giménez LM,Montilla-Herrador J,García-Vidal JA,Benítez-Martínez J

更新日期：2018-05-01 00:00:00

abstract：:Gastric acid is pathogenic in many gastrointestinal disorders, such as gastroesophageal reflux disease and peptic ulcer disease. Proton pump inhibitors (PPIs) are the antisecretory drugs of choice for serious acid-related conditions. Ample recent data exist to explicate virtually every aspect of the clinical managemen...

journal_title：International journal of clinical practice

authors： Robinson M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated the beneficial effect of normal and high body mass index (BMI) upon risk of osteoporosis (OP). No study has investigated the prevalence of OP in an older population with a very high BMI (higher than 40 kg/m(2) ). METHODS:Data of patients aged over 50 years that attended for a dual ...

journal_title：International journal of clinical practice

authors： Oldroyd A,Mitchell K,Bukhari M

更新日期：2014-06-01 00:00:00

abstract：:Motor restlessness, characterised by an irresistible urge to move about, can be a manifestation of many underlying disorders. Unfortunately, it is often poorly recognised and underdiagnosed in clinical practice, possibly because patients do not seek medical attention, or their complaints were thought to be secondary t...

journal_title：International journal of clinical practice

authors： Tan EK,Ondo WG

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:A significant proportion of COVID-19 patients may have cardiac involvement including arrhythmias. Although arrhythmia characterization and possible predictors were previously reported, there are conflicting data regarding the exact prevalence of arrhythmias. Clinically applicable algorithms to classify COVID...

journal_title：International journal of clinical practice

authors： Rav-Acha M,Orlev A,Itzhaki I,Zimmerman SF,Fteiha B,Bohm D,Kurd R,Samuel TY,Asher E,Helviz I,Glikson M,Michowitz Y

更新日期：2020-10-30 00:00:00

abstract：:Osteoporosis results from a decrease in bone strength yielding increased susceptibility to fractures. Hip and spine fractures are a major cause of morbidity and mortality in the elderly population. With an increasingly ageing world population, early prevention of bone loss is essential for adequate control of this con...

journal_title：International journal of clinical practice

authors： Reginster JY,Malaise O,Neuprez A,Bruyere O

更新日期：2007-02-01 00:00:00

abstract：AIMS:Studies on macrovascular consequences of glucose control in elderly patients (>75 years) with type 2 diabetes mellitus (T2DM) are lacking. The present study aimed to investigate the relationship between HbA(1c) and mortality in this specific population. METHODS:Between 1998 and 1999, 374 primary care patients wit...

journal_title：International journal of clinical practice

authors： van Hateren KJ,Landman GW,Kleefstra N,Drion I,Groenier KH,Houweling ST,Bilo HJ

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:People with depressive disorders or subsyndromal symptoms of depression (SSD) often use complementary and alternative therapies, including massage therapy (MT). This systematic review evaluates the evidence, from randomised clinical trials (RCTs), for the effectiveness of multiple sessions of classical Europ...

journal_title：International journal of clinical practice

authors： Coelho HF,Boddy K,Ernst E

更新日期：2008-02-01 00:00:00

abstract：:It is being questioned if Helicobacter pylori infection, which causes a chronic inflammatory response, can increase the frequency and severity of attacks in patients with Familial Mediterranean Fever (FMF) and if the impact of inflammatory response can be diminished by eradication of the infection. To evaluate if ther...

journal_title：International journal of clinical practice

authors： Ozel AM,Demirturk L,Aydogdu A,Gultepe M,Yazgan Y,Imirzalioglu N,Gurbuz AK,Narin Y

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Although there is a general agreement for the recommendation of the influenza vaccine to persons with chronic obstructive pulmonary disease (COPD), the magnitude of clinical effectiveness and benefit from the annual vaccination is controversial. We assessed the effects of annual influenza vaccination on wint...

journal_title：International journal of clinical practice

authors： Vila-Córcoles A,Ochoa O,de Diego C,Valdivieso A,Herreros I,Bobé F,Alvarez M,Juárez M,Guinea I,Ansa X,Saún N

更新日期：2008-01-01 00:00:00

abstract：:This double-blind, randomised placebo-controlled, multicentre study evaluated the efficacy, tolerability and safety of 12 weeks' treatment with controlled release darifenacin 15 mg once daily (qd), in 445 patients with overactive bladder (OAB). The primary endpoint was warning time (time from first sensation of urgenc...

journal_title：International journal of clinical practice

authors： Zinner N,Susset J,Gittelman M,Arguinzoniz M,Rekeda L,Haab F

更新日期：2006-01-01 00:00:00

abstract：:The aim of this study was to identify the aerobic and the anaerobic microorganisms which can be related to duct ectasia. The patients were divided into two groups. Group 1 comprised 100 patients with coloured nipple discharge (duct ectasia group), and Group 2 (the control group) was composed of 50 patients without nip...

journal_title：International journal of clinical practice

authors： Rahal RM,Júnior RF,Reis C,Pimenta FC,Netto JC,Paulinelli RR

更新日期：2005-09-01 00:00:00

abstract：:Ezetimibe/simvastatin (INEGY), a dual inhibitor of both cholesterol production and absorption, is a new approach to the management of hyperlipidaemia. Recent studies have shown that it produces greater reductions in low-density lipoprotein (LDL) cholesterol than the single inhibition of statin therapy, enabling many m...

journal_title：International journal of clinical practice

authors： Kastelein JJ,Sankatsing RR

更新日期：2005-12-01 00:00:00

abstract：:This open multicentre study compared the efficacy and tolerability of clarithromycin and spiramycin in the treatment of lower respiratory tract infections in Brazil and Colombia. A total of 125 patients with a clinical and radiological diagnosis of pneumonia, acute bronchitis or exacerbation of chronic bronchitis were...

journal_title：International journal of clinical practice

authors： Rocha RT,Awad CE,Ali A,Matyas R,Vital AC,Silva CO,Dainesi SM,Salazar MS,Nakatani J

更新日期：1999-09-01 00:00:00

abstract：INTRODUCTION:Peripheral arterial disease (PAD) is an underdiagnosed prevalent disease which implies high cardiovascular risk. Professionals usually depend on physical examination to screen for PAD. OBJECTIVE:To assess the diagnostic accuracy of physical examination to screen for PAD in a rural Primary Care population ...

journal_title：International journal of clinical practice

authors： Herráiz-Adillo Á,Piñar-Serrano O,Mariana-Herráiz JÁ,Martínez-Vizcaíno V,Pozuelo-Carrascosa DP,Notario-Pacheco B

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Lozenges containing Amylmetacresol and 2,4-Dichlorobenzylalcohol (AMC/DCBA, eg Strepsils® ) are marketed as a remedy for acute sore throat. This over-the-counter formulation has antiseptic and local anaesthetic qualities. OBJECTIVES:The objective of this systematic review and meta-analysis is to evaluate th...

journal_title：International journal of clinical practice

authors： Weckmann G,Hauptmann-Voß A,Baumeister SE,Klötzer C,Chenot JF

更新日期：2017-10-01 00:00:00

abstract：:'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...

journal_title：International journal of clinical practice

authors： Fava GA,Tomba E,Sonino N

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In clinical practice, hyponatraemia was frequently found in patients with hydrocephalus. We conducted this study to determine the prevalence and risk factors for hyponatraemia in patients with normal pressure hydrocephalus (NPH). METHODS:We retrospectively reviewed all patients with NPH who were admitted to...

journal_title：International journal of clinical practice

authors： Chou CY,Liu JH,Wang SM,Yang YF,Lin HH,Liu YL,Huang CC

更新日期：2009-03-01 00:00:00

abstract：:Systolic heart failure (SHF) is associated with increased morbidity and mortality. Beta-blockers (BB) were shown to provide mortality benefit in patients with SHF, and currently indicated in all stages of patients with SHF. We evaluated the factors influencing the prescription of BBs at discharge in patients hospitali...

journal_title：International journal of clinical practice

authors： Yilmaz MB,Refiker M,Guray Y,Guray U,Altay H,Demirkan B,Caldir V,Korkmaz S

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:In 2006, the American Diabetes Association and the European Association for the Study of Diabetes established a consensus algorithm (ADA/EASD-2006) for the adjustment of drug therapy for type 2 diabetes mellitus (T2DM). AIMS:To study glycaemic control in T2DM patients and the implementation of the ADA/EASD-...

journal_title：International journal of clinical practice

authors： Alvarez-Guisasola F,Guiada Study Group.

更新日期：2014-01-01 00:00:00

abstract：:Wiley has updated its publishing ethics guidelines, first published in 2006. The new guidelines provide guidance, resources and practical advice on ethical concerns that arise in academic publishing for editors, authors and researchers, among other audiences. New guidance is also included on whistle blowers, animal re...

journal_title：International journal of clinical practice

authors： Graf C,Deakin L,Docking M,Jones J,Joshua S,McKerahan T,Ottmar M,Stevens A,Wates E,Wyatt D

更新日期：2014-12-01 00:00:00