Abstract：
BACKGROUND:In clinical practice, hyponatraemia was frequently found in patients with hydrocephalus. We conducted this study to determine the prevalence and risk factors for hyponatraemia in patients with normal pressure hydrocephalus (NPH). METHODS:We retrospectively reviewed all patients with NPH who were admitted to China Medical University Hospital between 1998 and 2006. Hyponatraemia was defined as a plasma sodium concentration < 135 mEq/l on admission. Possible risk factors between patients with and without hyponatraemia were analysed using Student's t-test or chi2 test. The association between hyponatraemia and possible factors was analysed using multivariate logistic regression. The odds ratio was calculated to determine the effect of possible risk factors. RESULTS:A total of 146 patients (84 men and 62 women) who had NPH with a mean age of 66.1 +/- 15.9 years old were reviewed and 33 (22.6%) patients were found having hyponatraemia. Patients who developed hyponatraemia had a significantly higher prevalence of hypertension, use of nasogastric tube (NG), bed-ridden status and fever. In multivariate logistic regression, the presence of hypertension and the use of NG were two important risk factors for hyponatraemia. The odds ratio (95% CI) for hypertension and NG were 2.604 (95% CI: 1.136-5.967, p = 0.024) and 7.179 (95% CI: 2.3-22.409, p = 0.001) respectively. CONCLUSION:Hyponatraemia is not uncommon in patients with NPH. Physicians should be aware of this complication and obtain necessary laboratory examination for early detection of hyponatraemia.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Chou CY,Liu JH,Wang SM,Yang YF,Lin HH,Liu YL,Huang CCdoi
10.1111/j.1742-1241.2008.01925.xsubject
Has Abstractpub_date
2009-03-01 00:00:00pages
457-61issue
3eissn
1368-5031issn
1742-1241pii
IJCP1925journal_volume
63pub_type
杂志文章abstract：AIMS:Little is known on factors associated with switching and combination use of antidepressants. Our aim was to describe such use and to analyse the association with socioeconomic factors and level of care in Swedish adults aged 20-34 years. METHODS:Individuals, aged 20-34 years, who purchased an antidepressant in Ja...
journal_title：International journal of clinical practice
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更新日期：2013-12-01 00:00:00
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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abstract：BACKGROUND:Sleep-disordered breathing (SDB) is common in heart failure patients. Many of them still remain undiagnosed. The aim of this study was to detect clinical predictors of sleep apnoea which may help to identify patients with SDB at a heart failure clinic. METHODS:We performed an in-home sleep study on 115 cons...
journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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abstract：AIM:Osteoporosis and sarcopenia are common health problems in postmenopausal women. However, studies of these issues in premenopausal women are limited. Our present study aimed to investigate relationship the between underweight, bone mineral density (BMD) and skeletal muscle index (SMI) in a representative sample of p...
journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01505.x
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abstract：AIMS:To investigate the evolution of the quality of life of patients with chronic obstructive pulmonary disease (COPD) and quantify the impact of exacerbations on the deterioration of quality of life over 2 years. METHODS:Multicentre, observational, prospective 2-year study carried out in primary care. Patients with C...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
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更新日期：2008-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：2009-12-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2005-12-01 00:00:00
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更新日期：2010-02-01 00:00:00
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journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
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更新日期：2007-08-01 00:00:00
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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journal_title：International journal of clinical practice
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更新日期：2006-01-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2007-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：2004-12-01 00:00:00
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journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
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更新日期：2005-02-01 00:00:00
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journal_title：International journal of clinical practice
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