Proton pump inhibitors: update on their role in acid-related gastrointestinal diseases.

Abstract:

:Gastric acid is pathogenic in many gastrointestinal disorders, such as gastroesophageal reflux disease and peptic ulcer disease. Proton pump inhibitors (PPIs) are the antisecretory drugs of choice for serious acid-related conditions. Ample recent data exist to explicate virtually every aspect of the clinical management of acid-peptic disorders with PPIs. Although all PPIs are effective, there are some differences in their clinical performance, particularly in terms of the degree and speed of gastric acid suppression. Rapid onset of acid suppression may be particularly relevant to newer approaches, such as 'on-demand' or intermittent therapy for non-erosive reflux disease and shorter regimens for Helicobacter pylori eradication. New data, in addition, highlight differences in PPI metabolism that may both affect efficacy and predispose patients to drug-drug interactions. PPI selection should involve the awareness of these issues.

journal_name

Int J Clin Pract

authors

Robinson M

doi

10.1111/j.1368-5031.2005.00517.x

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

709-15

issue

6

eissn

1368-5031

issn

1742-1241

pii

IJCP517

journal_volume

59

pub_type

杂志文章,评审
  • Minor bleeding affects the level of knowledge in patients with atrial fibrillation on oral anticoagulant therapy.

    abstract:BACKGROUND:Anticoagulant therapy in patients with atrial fibrillation (AF) increases the risk of minor bleeding, which is mostly accepted by patients. We aimed to assess whether continuation of anticoagulation despite minor bleeding is associated with a higher level of knowledge on AF and anticoagulation. METHODS AND ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.13483

    authors: Metzgier-Gumiela A,Skonieczny G,Konieczyńska M,Desteghe L,Heidbuchel H,Undas A

    更新日期:2020-06-01 00:00:00

  • Switching to a rilpivirine/emtricitabine/tenofovir single-tablet regimen in RNA-suppressed patients infected with human immunodeficiency virus 1: Effectiveness, safety and costs at 96 weeks.

    abstract:OBJECTIVES:This study evaluates the effectiveness, safety and costs of switching to a rilpivirine/emtricitabine/tenofovir disoproxil fumarate (RPV/FTC/TDF) regimen in treatment-experienced HIV-1-infected patients with sustained virological suppression. METHODS:Observational, prospective study. Study population include...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.12968

    authors: Arrabal-Durán P,Rodríguez-González CG,Chamorro-de-Vega E,Gijón-Vidaurreta P,Herranz-Alonso A,Sanjurjo-Sáez M

    更新日期:2017-08-01 00:00:00

  • Efficacy and safety of once-weekly glucagon-like peptide-1 receptor agonists compared with exenatide and liraglutide in type 2 diabetes: a systemic review of randomised controlled trials.

    abstract:BACKGROUND:Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promising results in the treatment of type 2 diabetes. Herein, we compared the efficacy and safety of once-weekly GLP-1RAs with exenatide and liraglutide separately. METHODS:We systematically surveyed the pertinent literature using ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/ijcp.12847

    authors: Xue X,Ren Z,Zhang A,Yang Q,Zhang W,Liu F

    更新日期:2016-08-01 00:00:00

  • L-thyroxin treatment in infants with hyperthyrotropinaemia: 4-year experience.

    abstract::Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1742-1241.2006.00998.x

    authors: Demirel F,Bideci A,Camurdan MO,Cinaz P

    更新日期:2007-08-01 00:00:00

  • Beclomethasone dipropionate Easyhaler is as effective as budesonide Turbohaler in the control of asthma and is preferred by patients. German Study Group.

    abstract::This randomised, crossover study compared the efficacy, safety, acceptability and patient preference of two multidose powder inhalers (MDPIs)--beclomethasone dipropionate Easyhaler (BDP-EH) and budesonide Turbohaler (BUD-TH)--in 79 stable asthmatics who used inhaled steroids but had no experience of MDPIs. After eight...

    journal_title:International journal of clinical practice

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Jäger L,Laurikainen K,Leinonen M,Silvasti M

    更新日期:2000-07-01 00:00:00

  • Motor restlessness.

    abstract::Motor restlessness, characterised by an irresistible urge to move about, can be a manifestation of many underlying disorders. Unfortunately, it is often poorly recognised and underdiagnosed in clinical practice, possibly because patients do not seek medical attention, or their complaints were thought to be secondary t...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:

    authors: Tan EK,Ondo WG

    更新日期:2001-06-01 00:00:00

  • First seizure - to treat or not to treat?

    abstract:BACKGROUND:The decision on whether or not to treat a first seizure is dependent on several medical and non-medical factors. AIMS:In this review, we have summarised the important aspects that determine the advantages and disadvantages of treating a first seizure. We have looked at evidence from randomised controlled tr...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1742-1241.2008.01896.x

    authors: Sathasivam S,Nicolson A

    更新日期:2008-12-01 00:00:00

  • The impact of age on 6-month survival in patients with cardiovascular risk factors undergoing elective non-cardiac surgery.

    abstract::An increasing number of patients aged>or=70 years are presenting for elective non-cardiac surgery. We undertook this study to: (i) compare the nature and distribution of cardiovascular disease (CVD) risk factors in an at risk population of patients aged>or=70 years undergoing elective surgery compared with a younger a...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1742-1241.2007.01304.x

    authors: Naughton C,Feneck RO

    更新日期:2007-05-01 00:00:00

  • Bone turnover 18 months after a single intravenous dose of zoledronic acid.

    abstract::Zoledronic acid inhibits bone resorption for up to 12 months. It is not known whether the duration of this antiresorptive effect extends beyond this period of time. The aim of this study was to evaluate the changes in bone turnover at 12 months (T12) and 18 months (T18) after a single injection of 4 mg of zoledronic a...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1742-1241.2007.01392.x

    authors: Borba VZ,Paz-Filho G,Kulak CA,Seibel MJ,Bilezikian JP

    更新日期:2007-06-01 00:00:00

  • The long-term cost-effectiveness of varenicline (12-week standard course and 12 + 12-week extended course) vs. other smoking cessation strategies in Canada.

    abstract:BACKGROUND:Smoking is the leading risk factor for preventable morbidity and mortality as a result of heart and lung diseases and various forms of cancer. Reimbursement coverage for smoking cessation therapies remains limited in Canada and the United States despite the health and economic benefits of smoking cessation. ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.12363

    authors: von Wartburg M,Raymond V,Paradis PE

    更新日期:2014-05-01 00:00:00

  • Patent foramen ovale and cryptogenic stroke: from studies to clinical practice: Position paper of the Italian Chapter, International Society Cardiovascular Ultrasound.

    abstract:BACKGROUND:Over the last two decades the interest on patent foramen ovale (PFO) as a cause of cardioembolism in cryptogenic stroke has tremendously increased, thanks to the availability of better techniques to diagnose cardiac right-to-left shunt by ultrasounds and of percutaneous means of PFO treatment with interventi...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/ijcp.12842

    authors: Savino K,Maiello M,Pelliccia F,Ambrosio G,Palmiero P

    更新日期:2016-08-01 00:00:00

  • Targets and tactics: the relative importance of HbA, fasting and postprandial plasma glucose levels to glycaemic control in type 2 diabetes.

    abstract:BACKGROUND:The incidence of type 2 diabetes is reaching pandemic proportions, impacting patients and healthcare systems across the globe. Evidence suggests that a majority of patients are not achieving recommended blood glucose targets resulting in an increased risk of micro- and macro-vascular complications. AIM:To r...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1742-1241.2008.01941.x

    authors: Woo V,Shestakova MV,Ørskov C,Ceriello A

    更新日期:2008-12-01 00:00:00

  • Patient-controlled sedation vs. anaesthetic nurse-controlled sedation for cataract surgery in elderly patients.

    abstract:BACKGROUND:Patient-controlled sedation (PCS) with propofol has been used successfully in various conditions, but controversies exist about its use in sedation of elderly patients for cataract surgery. This study evaluates the efficacy of anaesthetic nurse-controlled sedation (ACS) compared with PCS using the same devic...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1742-1241.2007.01544.x

    authors: Yun MJ,Oh AY,Kim KO,Kim YH

    更新日期:2008-05-01 00:00:00

  • Evidence-based pharmacologic treatment for mild asthma.

    abstract:BACKGROUND:Although mild asthmatics form the majority of asthma sufferers, there is a relative paucity of evidence-based treatment compared with severe asthmatics. OBJECTIVE:We have performed an up-to-date review of the literature on therapy in this group of patients who form an overlooked but important majority. Pote...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1742-1241.2007.01410.x

    authors: Koh MS,Irving LB

    更新日期:2007-08-01 00:00:00

  • Impact on clinical practice of the Joint British Societies' cardiovascular risk assessment tools.

    abstract:OBJECTIVES:The aim of this study was to evaluate the Joint British Societies' (JBS 2) Factfile, cardiovascular risk assessment paper charts and electronic risk calculator posted to health professionals in general practice. DESIGN:Phase one: surveys on use of the JBS 2 charts and calculator; views on improving use and ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1742-1241.2009.02201.x

    authors: Kirby M,Machen I

    更新日期:2009-12-01 00:00:00

  • Chemotherapy for the treatment of hormone-refractory prostate cancer.

    abstract:AIMS:This review aims at analysing the published literature on chemotherapy for hormone-refractory prostate cancer (HRPC) to provide recommendations for the treatment of this important patient group. METHODS:The information for this review was compiled using the PubMed and Medline databases and the Proceedings of the ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1742-1241.2007.01551.x

    authors: Chowdhury S,Burbridge S,Harper PG

    更新日期:2007-12-01 00:00:00

  • Serum levels of IGF-I and IGFBP-III and their relation with carcinoembryonic antigen and carbohydrate antigen 19-9 in cases of esophageal cancer.

    abstract::Tumour markers are used for diagnosis, staging, evaluation of response to treatment, prognosis and detection of recurrences in clinical oncology. In this study, we aim to investigate the levels of insulin-like growth factor (IGF)-I and IGF-binding protein (IGFBP)-III in cases with oesophageal carcinoma. We investigate...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/j.1742-1241.2006.00854.x

    authors: Yilmaz O,Eroglu A,Dag E,Karaoglanoglu N,Yilmaz A

    更新日期:2006-12-01 00:00:00

  • Words will never hurt me? Preferred terms for describing obesity and binge eating.

    abstract:OBJECTIVE:This study evaluated individuals' language preferences for discussing obesity and binge eating. METHOD:Participants (N = 817; 68.3% female) were an online community sample. They rated the desirability of terms related to obesity and binge eating, and also completed psychometrically established eating-disorde...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.12835

    authors: Lydecker JA,Galbraith K,Ivezaj V,White MA,Barnes RD,Roberto CA,Grilo CM

    更新日期:2016-08-01 00:00:00

  • Ideal pain relief following laparoscopic cholecystectomy.

    abstract::In a previous report the effectiveness of intraperitoneal bupivacaine in reducing pain following laparoscopic cholecystectomy was demonstrated. Other methods of pain relief are commonly used but none has been compared following laparoscopic cholecystectomy. In two further studies we have compared the analgesic effect ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:

    authors: Johnson RC,Hedges AR,Morris R,Stamatakis JD

    更新日期:1999-01-01 00:00:00

  • Clinical predictors of sleep apnoea in heart failure outpatients.

    abstract:BACKGROUND:Sleep-disordered breathing (SDB) is common in heart failure patients. Many of them still remain undiagnosed. The aim of this study was to detect clinical predictors of sleep apnoea which may help to identify patients with SDB at a heart failure clinic. METHODS:We performed an in-home sleep study on 115 cons...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.12396

    authors: Herrscher TE,Akre H,Overland B,Sandvik L,Westheim AS

    更新日期:2014-06-01 00:00:00

  • Incontinence in adult females with cystic fibrosis: a Northern Ireland survey.

    abstract::The objectives of this survey were to establish the prevalence, onset, severity and impact of incontinence and attitudes towards the availability of advice and treatment in female adults with cystic fibrosis (CF) in Northern Ireland. All female patients (n=59) at the Northern Ireland Regional Adult CF Centre were post...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:

    authors: Moran F,Bradley JM,Boyle L,Elborn JS

    更新日期:2003-04-01 00:00:00

  • Ethnic differences in peripheral vascular disease.

    abstract::The wide variation in the way coronary artery disease (CAD) affects different ethnic groups and the associated risk factor profiles of these groups have been extensively studied, but ethnic differences in the clinical manifestations of peripheral vascular disease (PVD) have been relatively neglected. The aim of the pr...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:

    authors: Makin A,Silverman S,Lip GY

    更新日期:2002-10-01 00:00:00

  • Exploring the needs and expectations of women presenting for hysterosalpingogram examination following a period of subfertility: a qualitative study.

    abstract:AIMS:This study examines women's experience of healthcare following the referral for hysterosalpingography (HSG) after a period of subfertility. These otherwise fit and healthy women enter the healthcare system and their only problem is a failure to become pregnant. They find themselves trying to negotiate a system des...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,评审

    doi:10.1111/j.1742-1241.2010.02431.x

    authors: Williams M,Green L,Roberts K

    更新日期:2010-11-01 00:00:00

  • Perceived Maternal Parenting Self-Efficacy as a Predictor Maternal Responsiveness in Infants and Toddlers.

    abstract:BACKGROUND:Maternal responsiveness seems to be necessary for a child to develop a safe attachment. However, even after many years of research on maternal responsiveness, only a few attempts have been made to find ways of promoting mother and child interaction. This study aimed at determining the association between mat...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.14043

    authors: Abuhammad S

    更新日期:2021-01-23 00:00:00

  • The combination of amlodipine/valsartan 5/160 mg produces less peripheral oedema than amlodipine 10 mg in hypertensive patients not adequately controlled with amlodipine 5 mg.

    abstract:AIMS:To demonstrate the benefit of the combination amlodipine/valsartan 5/160 mg over amlodipine 10 mg, in producing a lower incidence of peripheral oedema for a comparable mean sitting systolic blood pressure (MSSBP) reduction. METHODS:After a 4-week amlodipine 5 mg run-in phase, inadequately controlled hypertension ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1742-1241.2008.01977.x

    authors: Schrader J,Salvetti A,Calvo C,Akpinar E,Keeling L,Weisskopf M,Brunel P

    更新日期:2009-02-01 00:00:00

  • Computer vision syndrome and ergonomic practices among undergraduate university students.

    abstract:AIM:To determine the prevalence of computer vision syndrome (CVS) and ergonomic practices among students in the Faculty of Medical Sciences at The University of the West Indies (UWI), Jamaica. METHOD:A cross-sectional study was done with a self-administered questionnaire. RESULTS:Four hundred and nine students partic...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.13035

    authors: Mowatt L,Gordon C,Santosh ABR,Jones T

    更新日期:2018-01-01 00:00:00

  • Diagnostic accuracy of non-radiologist performed ultrasound for abdominal aortic aneurysm: systematic review and meta-analysis.

    abstract:BACKGROUND:Ultrasonography is increasingly used by clinicians to identify abdominal aortic aneurysms (AAA). We performed a systematic review and meta-analysis comparing the accuracy of non-radiologist performed ultrasound (NRPUS) for AAA disease to the 'gold standard' of radiologist performed aortic imaging (RPI), intr...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ijcp.12453

    authors: Concannon E,McHugh S,Healy DA,Kavanagh E,Burke P,Clarke Moloney M,Walsh SR

    更新日期:2014-09-01 00:00:00

  • Clinicopathological and therapeutic patterns of idiopathic pulmonary fibrosis in Kuwait: a prospective study.

    abstract::Though common, the exact incidence and clinical pattern of idiopathic pulmonary fibrosis (IPF) in Gulf countries are not known. The results of a four-year prospective study undertaken in two tertiary hospitals in Kuwait are presented. The mean age at diagnosis of the 52 patients studied was 55.40 +/- 11.87 years. Thir...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Khadadah ME,Onadeko BO,Abul AT,Behbehan NA,Cerna M,Cherian JM,Adesina O,Maradni N,Jayakrishnan B

    更新日期:2003-12-01 00:00:00

  • Synonymous polymorphism rs201256011 in dopamine receptor type 2 gene is associated with schizophrenia and PANSS score in Pakistani population: A first report.

    abstract:AIM:Variations of dopamine receptor type 2 (DRD2) are among the key factors involved in the pathology of schizophrenia. Presence of certain SNPs in DRD2 gene also amend patients' response to antipsychotics. Keeping in view the genetic diversity among populations and important role of DRD2 polymorphisms in schizophrenia...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:10.1111/ijcp.13536

    authors: Amir QU,Hanif F,Washdev W,Bilwani F,Usman Simjee S

    更新日期:2020-09-01 00:00:00

  • An unusual cause of carpal tunnel syndrome.

    abstract::Tuberculosis is an uncommon cause of carpal tunnel syndrome. We report a patient with systemic lupus erythematosus who developed hand numbness. Ultrasonic, operative and microbiological findings supported the diagnosis of median nerve compression secondary to a tuberculous abscess. The symptoms resolved with surgical ...

    journal_title:International journal of clinical practice

    pub_type: 杂志文章

    doi:

    authors: Hui AC,Wong SM,Griffith JF

    更新日期:2003-09-01 00:00:00