Abstract：
:In a previous report the effectiveness of intraperitoneal bupivacaine in reducing pain following laparoscopic cholecystectomy was demonstrated. Other methods of pain relief are commonly used but none has been compared following laparoscopic cholecystectomy. In two further studies we have compared the analgesic effect of intraperitoneal bupivacaine against wound infiltration with bupivacaine, and against intraperitoneal bupivacaine with the addition of a non-steroidal anti-inflammatory drug (NSAID) in patients undergoing laparoscopic cholecystectomy. Two consecutive studies were performed. In the first, patients in group 1 were given 20 ml of 0.25% bupivacaine into the peritoneal cavity; patients in group 2 were given 20 ml of 0.25% bupivacaine injected into the trocar wounds. In the second study, patients in group 1 were given 20 ml of 0.25% bupivacaine into the peritoneal cavity; patients in group 2 were given 20 ml of 0.25% bupivacaine into the peritoneal cavity and a diclofenac suppository (100 mg) one hour before surgery. Postoperative pain was assessed with a visual analogue pain scale. There was no difference in pain scores in the two groups in either study. Intraperitoneal bupivacaine is as effective as wound infiltration. The addition of an NSAID makes no difference in the reduction of postoperative pain following laparoscopic cholecystectomy.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Johnson RC,Hedges AR,Morris R,Stamatakis JDsubject
Has Abstractpub_date
1999-01-01 00:00:00pages
16-8issue
1eissn
1368-5031issn
1742-1241journal_volume
53pub_type
杂志文章abstract：BACKGROUND:People with depressive disorders or subsyndromal symptoms of depression (SSD) often use complementary and alternative therapies, including massage therapy (MT). This systematic review evaluates the evidence, from randomised clinical trials (RCTs), for the effectiveness of multiple sessions of classical Europ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01553.x
更新日期：2008-02-01 00:00:00
abstract：:Despite concerns in the 1970s and 1980s about the safety of short-acting beta2-agonists, it is now generally accepted that these agents, used at appropriate doses, provide safe and effective treatment for asthma symptoms. After their introduction, beta2-agonists with a long duration of action--formoterol and salmetero...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2003-10-01 00:00:00
abstract：:To investigate the influence of the S447X variant in lipoprotein lipase (LPL) gene on the response rate to therapy with the thiazolidinedione pioglitazone. A total of 113 diabetic patients were treated with pioglitazone 30 mg for 10 weeks. Response to the pioglitazone treatment was defined by either a >10% relative re...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章
doi：10.1111/j.1742-1241.2006.01242.x
更新日期：2007-04-01 00:00:00
abstract：:The purpose of this survey was to ascertain which physiotherapy techniques are currently used, how interventions are assessed and to determine the views of physiotherapists in the UK on the need for further research. Senior physiotherapists in 100 randomly selected hospitals providing respiratory care in the UK were s...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:The clinical syndrome of anaphylaxis and anaphylactoid reactions is quite variable, making diagnosis difficult at times. Early recognition by patient or physician is imperative to appropriate management. Recurrences may be life-threatening if the initial diagnosis is incorrect, as patients do not avoid the offending a...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：AIMS:To assess the extent of reduction in blood pressure (BP) of aliskiren/amlodipine combination therapy compared with amlodipine monotherapy in moderate-to-severe hypertensive patients. METHODS:This was an 8-week multicentre, randomised, double-blind study. After a 1-to 4-week washout period, eligible patients [mean...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1742-1241.2012.02967.x
更新日期：2012-09-01 00:00:00
abstract：AIM:Variations of dopamine receptor type 2 (DRD2) are among the key factors involved in the pathology of schizophrenia. Presence of certain SNPs in DRD2 gene also amend patients' response to antipsychotics. Keeping in view the genetic diversity among populations and important role of DRD2 polymorphisms in schizophrenia...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13536
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND/AIMS:The consumption of soft drinks has increased considerably during the last decades. Among them, the cola-based preparations are possibly the refreshments with the largest sales worldwide. In addition to the possible detrimental effects of moderate, chronic cola consumption, it has been proposed that the ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2009.02051.x
更新日期：2009-06-01 00:00:00
abstract：:Tissue inflammation has been linked to cancer in several disease models. We tested the association between chronic inflammation and prostate cancer (PCa), as well as high-grade prostatic intraepithelial neoplasia (HGPIN), in prostatic needle biopsy specimens. Tissues from 4526 men, who underwent systematic ultrasound-...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.00905.x
更新日期：2007-03-01 00:00:00
abstract：:In the vast majority of cases, Clostridium difficile-associated diarrhoea and pseudomembranous colitis develop following the use of antibiotics. We report a case in which C. difficile-associated diarrhoea was diagnosed in the absence of previously reported predisposing factors. It transpired that the patient had a col...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:A case of a child with acute cerebellar ataxia associated with chickenpox virus infection is described. Acute cerebellar ataxia associated with chickenpox is a well-recognised complication and the pertinent features of this condition are discussed. ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Complementary medicine and alternative approaches to chronic and intractable health conditions are increasingly being used, and require critical evaluation. OBJECTIVE:The aim of this review was to systematically evaluate available evidence for the effectiveness and safety of instruction in the Alexander Tec...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2011.02817.x
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Temporomandibular disorders (TMD) are the most common orofacial impairment, but the relevance of certain clinical features in TMD is not clear. OBJECTIVE:The main objective of this study was to analyse if temporomandibular disorders (TMD) are associated with sociodemographic (eg age, height, weight, body ma...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13961
更新日期：2021-01-02 00:00:00
abstract：:In recent years the complexities and heterogeneity of polycystic ovarian syndrome (PCOS) have been recognised. Most PCOS sufferers with amenorrhoea, menstrual dysfunction, hirsutism, acne and infertility can be evaluated and safely managed in primary care. It is prudent to remember that all women with PCOS are at risk...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND:Upper gastrointestinal (UGI) haemorrhage is a frequent cause of hospital admission. Scoring systems have been devised to identify those at risk of adverse outcomes. We evaluated the Glasgow Blatchford score's (GBS) ability to identify the need for clinical and endoscopic intervention in patients with UGI hae...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2009.02267.x
更新日期：2010-06-01 00:00:00
abstract：:The aim of this study was to audit the preoperative administration of regular cardiac medication in general surgical patients and to determine if this can be improved with simple ward-based education. The notes and drug charts of 102 general surgical adult inpatients undergoing elective operations were analysed prospe...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.01002.x
更新日期：2006-10-01 00:00:00
abstract：AIMS:Patients with advanced type 2 diabetes (T2D) and high glycated haemoglobin (HbA1c) values can be difficult to treat because of their severe metabolic disease. This pooled analysis examined the treatment effects of exenatide twice daily (BID), exenatide once weekly (QW) and insulin in patients with high baseline Hb...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/ijcp.13029
更新日期：2017-12-01 00:00:00
abstract：:Haematogenous metastases to the small bowel are a rare occurrence, usually from malignant melanoma or bronchogenic carcinoma. There are occasional reports of other primary tumours presenting with small bowel involvement as the first evidence of metastases. We describe a case of intraluminal jejunal metastasis from a r...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND/AIMS:Simple compound of Helicobacter pylori eradication therapy may improve drug compliance of patients. The aims of this study were to compare the efficacy and tolerability of a simple combination containing levofloxacin 7-day once-daily with standard twice-daily triple therapy. PATIENTS AND METHODS:This w...
journal_title：International journal of clinical practice
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1742-1241.2010.02482.x
更新日期：2010-10-01 00:00:00
abstract：:Lithium salts have been used in medicine for over a century and are a widely accepted treatment. Clinical practice in the London borough of Barnet led us to suspect that agreed guidelines were not being followed. We checked them against published guidelines and followed up their implementation. A list of patients on l...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：:Linear regression methods try to determine the best linear relationship between data points while correlation coefficients assess the association (as opposed to agreement) between the two methods. Linear regression and correlation play an important part in the interpretation of quantitative method comparison studies. ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2008.01709.x
更新日期：2008-04-01 00:00:00
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journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01302.x
更新日期：2007-09-01 00:00:00
abstract：:The misery of living with atopic eczema (syn. dermatitis, AD) cannot be overstated for it may have a profoundly negative effect on the health-related quality of life (HRQoL) of children and their family unit in many cases. As it is one of the commonest chronic relapsing childhood dermatosis (UK lifetime prevalence 16-...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2006.01047.x
更新日期：2006-08-01 00:00:00
abstract：:TT virus (TTV) is a novel DNA virus that has been identified in patients with post-transfusional hepatitis of unknown aetiology. However, its pathogenic role in liver injury remains unclear. To determine its frequency and clinical impact in cryptogenic liver diseases, we investigated the TTV prevalence in patients wit...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:A retrospective audit of (99m)Tc-HMPAO SPECT scans was undertaken to assess the utility of brain perfusion imaging in a cohort of young cognitively impaired patients in whom diagnostic uncertainty remained after standard clinical and neuropsychological assessment and structural brain imaging. SPECT scans were assessed...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1368-5031.2005.00499.x
更新日期：2005-04-01 00:00:00
abstract：AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...
journal_title：International journal of clinical practice
pub_type： 杂志文章,随机对照试验
doi：10.1111/ijcp.12944
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Although there is a general agreement for the recommendation of the influenza vaccine to persons with chronic obstructive pulmonary disease (COPD), the magnitude of clinical effectiveness and benefit from the annual vaccination is controversial. We assessed the effects of annual influenza vaccination on wint...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2007.01414.x
更新日期：2008-01-01 00:00:00
abstract：:Erectile dysfunction (ED) shares the same risk factors as coronary artery disease, so the level of occult cardiovascular risk in men with ED was assessed. A total of 174 men presenting with ED underwent cardiac risk stratification according to the Princeton Consensus Guidelines. Thirty per cent were stratified as inte...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Buprenorphine is a semi-synthetic opioid derived from thebaine. The transdermal formulation of buprenorphine has been available in Belgium for 3 years, during which time the Pain Clinic of the St Elisabeth of Verviers Hospital has gained experience in the use of transdermal buprenorphine for the treatment of moderate-...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.01109.x
更新日期：2006-10-01 00:00:00
abstract：:The porphyrias comprise a group of disorders of the haem biosynthesis pathway that can present with acute neurovisceral symptoms, skin lesions or both. Acute porphyrias present with severe abdominal pain, confusion and seizures which may be life-threatening. Specific treatment with haem preparations should be institut...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2002-05-01 00:00:00
