L-thyroxin treatment in infants with hyperthyrotropinaemia: 4-year experience.

abstract：BACKGROUND:Subjects with the metabolic syndrome are accompanied by insulin resistance (IR). However, it is not clear how well the newly defined metabolic syndrome identifies IR specifically in hypertensive subjects. AIMS:The purpose of the study was to evaluate the performance of the metabolic syndrome, defined by the...

journal_title：International journal of clinical practice

authors： Hwu CM,Hsiung CA,Wu KD,Lee WJ,Shih KC,Grove J,Chen YD,Rodriguez BL,Curb JD,SAPPHIRe Study Group.

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Patient-controlled sedation (PCS) with propofol has been used successfully in various conditions, but controversies exist about its use in sedation of elderly patients for cataract surgery. This study evaluates the efficacy of anaesthetic nurse-controlled sedation (ACS) compared with PCS using the same devic...

journal_title：International journal of clinical practice

authors： Yun MJ,Oh AY,Kim KO,Kim YH

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Elevated levels of blood lipids are considered a major modifiable risk factor for the development of cardiovascular diseases. The optimal management of dyslipidaemia remains inadequate worldwide. Accordingly, there is an increasing need to evaluate the basis that health care providers are using to control dy...

journal_title：International journal of clinical practice

authors： Rababa'h AM,Mustafa R,Rabab'ah M,Khasawneh M,Ababneh M,Khraisha S,Altarabsheh SE

更新日期：2020-10-23 00:00:00

abstract：:The aim of this study was to audit the preoperative administration of regular cardiac medication in general surgical patients and to determine if this can be improved with simple ward-based education. The notes and drug charts of 102 general surgical adult inpatients undergoing elective operations were analysed prospe...

journal_title：International journal of clinical practice

authors： Corfield LF,Trivedi PM,Wilson D

更新日期：2006-10-01 00:00:00

abstract：:There has been much debate over the past 50 years concerning the association between colorectal carcinoma and inflammatory bowel disease. Until recently, it was widely accepted there was a higher risk in those with widespread ulcerative colitis. However, evidence now suggests an almost equal incidence in those with Cr...

journal_title：International journal of clinical practice

authors： Kirk GR,Clements WD

更新日期：1999-06-01 00:00:00

abstract：:A retrospective audit of (99m)Tc-HMPAO SPECT scans was undertaken to assess the utility of brain perfusion imaging in a cohort of young cognitively impaired patients in whom diagnostic uncertainty remained after standard clinical and neuropsychological assessment and structural brain imaging. SPECT scans were assessed...

journal_title：International journal of clinical practice

authors： Doran M,Vinjamuri S,Collins J,Parker D,Larner AJ

更新日期：2005-04-01 00:00:00

abstract：:In 2006 Meiron Thomas, writing in the British Journal of Surgery, made the following statement about the value of sentinel lymph node biopsy (SLNB) as a staging procedure in cutaneous malignant melanoma (1): "Perhaps a more important concern for those hoping to gain reassurance from accurate nodal staging relates to p...

journal_title：International journal of clinical practice

authors： Russell-Jones R

更新日期：2012-07-01 00:00:00

abstract：AIM OF THE STUDY:We designed a retrospective, monocentric, observational study to assess the efficacy and short-term side effect profile of desmopressin, a synthetic analogue of antidiuretic hormone, in 42 elderly patients affected by nocturnal polyuria (NP), a subset of nocturia (nocturnal overproduction of urine at n...

journal_title：International journal of clinical practice

authors： Palmieri B,Iannitti T,Morales-Medina JC,Vadalà M

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:Erectile dysfunction (ED) is common in older age and in diabetes mellitus (DM). Phosphodiesterase type 5-inhibitors (PDE5-is) are the first-line for ED. We investigated how the type of diabetes and age of males affect the PDE5-i use in the primary care setting. METHODS:From 2018 to 2019, the general pract...

journal_title：International journal of clinical practice

authors： Stedman M,Whyte MB,Lunt M,Albanese M,Livingston M,Gadsby R,Hackett G,Anderson SG,Heald AH

更新日期：2020-09-01 00:00:00

abstract：:A randomised, double-blind, parallel, placebo-controlled, 12-week study was carried out to evaluate the efficacy and safety of 20-mg tadalafil taken 'as needed' in a population of men with erectile dysfunction (ED) from Egypt and Turkey. One hundred and thirty-two patients were randomised in this study. Tadalafil was ...

journal_title：International journal of clinical practice

authors： Saylan M,Khalaf I,Kadioglu A,Shoair KZ,Beheiry A,Wang WC,Kopernicky V,Esen A

更新日期：2006-07-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with gastrointestinal adverse effects, ranging from dyspepsia and peptic ulcer disease to more serious complications such as haemorrhage or perforation. NSAID-induced gastrointestinal toxicity is a significant medical problem worldwide. Misoprostol is effec...

journal_title：International journal of clinical practice

authors： Singh G,Triadafilopoulos G

更新日期：2005-10-01 00:00:00

abstract：:Erectile Dysfunction (ED) is common in men with diabetes. Diabetic men are three times as likely to develop ED as non-diabetic men. The cause is multifactorial, but most commonly reflects endothelial dysfunction and autonomic neuropathy. Diabetes and vascular disease often coexist and ED may be a marker for silent occ...

journal_title：International journal of clinical practice

authors： Jackson G

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:In late July, Cyprus experienced the second epidemic wave of COVID-19. We present the steps taken by the government and evaluate their effect on epidemic trends. MATERIALS:Cyprus Press and Information Office data were analysed. Using an R-based forecasting program, two models were created to predict cases u...

journal_title：International journal of clinical practice

authors： Kakoullis L,Eliades E,Papachristodoulou E,Parperis K,Chra P,Constantinidou A,Chatzittofis A,Sampsonas F,Panos G

更新日期：2020-12-18 00:00:00

abstract：AIMS:The aim of this study was to assess patient characteristics, medication treatment patterns and healthcare resource utilization among men with existing erectile dysfunction (ED) or benign prostatic hyperplasia (BPH), who are newly diagnosed with the second condition (BPH or ED) compared with those with only one con...

journal_title：International journal of clinical practice

authors： Ilo D,Raluy-Callado M,Graham-Clarke P,Sadasivan R,Birt J,Donaldson R,Zhu E,Kirby MG,Neasham D

更新日期：2015-08-01 00:00:00

abstract：:Despite potential benefits, primary care clinicians may avoid using antimuscarinics in men with overactive bladder (OAB) symptoms because of safety concerns. To review the efficacy and safety of antimuscarinics, alone or in combination with an α-blocker, for the treatment of men with OAB symptoms, we conducted a syste...

journal_title：International journal of clinical practice

authors： Kaplan SA,Roehrborn CG,Abrams P,Chapple CR,Bavendam T,Guan Z

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Intravenous azithromycin (AZM) has been widely used in children worldwide, but there still remains much concern regarding its off-label use, which urgently needs to be regulated. Therefore, we developed a rapid advice guideline in China to give recommendations of rational use of intravenous AZM in children. ...

journal_title：International journal of clinical practice

authors： Zhou P,Wang X,Zhang X,Xu B,Tong X,Zhou W,Shen K,Zhai S

更新日期：2021-01-09 00:00:00

abstract：:Carcinoma erysipelatoides, also known as inflammatory metastatic carcinoma, is a rare form of cutaneous metastasis from a malignancy. The characteristic histopathological finding is metastatic tumour cells inside the dermal lymphatic ducts. It is frequently observed in patients with breast carcinoma as well as adenoca...

journal_title：International journal of clinical practice

authors： Yu KJ,Lee HE,Ho HC,Lee JC,Chang JW,Hong HS,Yang CH

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to explore the feasibility of using low dose radiation and low concentration contrast media in enhanced CT examinations in children with congenital heart disease. MATERIALS AND METHODS:Ninety patients with congenital heart disease were randomly divided into three groups of 30 patien...

journal_title：International journal of clinical practice

authors： Liu Z,Song L,Yu T,Gao J,Zhang Q,Jiang L,Liu Y,Peng Y

更新日期：2016-09-01 00:00:00

abstract：:Of the 25,000 new cases of breast cancer annually in the UK, at least half will develop metastases at some time. Approximately one-third of these will be hormone-sensitive and thus suitable for endocrine manipulation. Such patients may live for several years. Care should be patient-centred and evidence-based, with pri...

journal_title：International journal of clinical practice

authors： Theobald AJ

更新日期：2000-12-01 00:00:00

abstract：AIM:Splenectomised patients are associated with lifelong risk of fatal overwhelming post-splenectomy infection (OPSI), which is mostly caused by Streptococcus pneumoniae. Today OPSI cases can still be reported even in patients with appropriate vaccination. In our study, the levels of vaccine-specific memory B- and T ce...

journal_title：International journal of clinical practice

authors： Gazi U,Karasartova D,Sahiner IT,Gureser AS,Tosun O,Derici MK,Dolapci M,Taylan Ozkan A

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of linagliptin in initial combination with metformin in patients with type 2 diabetes. METHODS:This 1-year randomised, double-blind study was an extension of a 6-month randomised controlled trial, in which adults with type 2 diabetes received one of six treatment regimens...

journal_title：International journal of clinical practice

authors： Haak T,Meinicke T,Jones R,Weber S,von Eynatten M,Woerle HJ

更新日期：2013-12-01 00:00:00

abstract：:Cystic fibrosis (CF) is one of the commonest lethal inherited conditions among Caucasians. It affects multiple organ systems and exhibits a range of clinical problems of varying severity. Life expectancy has improved in recent years as treatment regimes have become more intensive, but current treatments are expensive,...

journal_title：International journal of clinical practice

authors： Lees CM,Smyth RL

更新日期：2000-04-01 00:00:00

abstract：AIMS:Early clinical trials suggest that blood-derived stem/progenitor cells (including peripheral blood-derived stem cells and circulating progenitor cells) may have a positive impact on patients with ischaemic heart disease (IHD). The therapeutic effects of these cells remain unclear, considering the inconsistent resu...

journal_title：International journal of clinical practice

authors： Wen Y,Meng L,Ding Y,Ouyang J

更新日期：2011-08-01 00:00:00

abstract：AIMS:We aimed to assess the prevalence, components and evolution of polypharmacy and to evaluate risk factors associated with polypharmacy. METHODS:A retrospective dynamic cohort study was performed, using a primary healthcare database comprising Flemish community-dwelling adults aged ≥40 years between 2011 and 2015. ...

journal_title：International journal of clinical practice

authors： Hellemans L,Nuyts S,Hias J,van den Akker M,Van Pottelbergh G,Rygaert X,Spriet I,Vaes B,Tournoy J,Van der Linden L

更新日期：2020-12-19 00:00:00

abstract：BACKGROUND:Urinary tract infections (UTI) and asymptomatic bacteriuria (AB) during pregnancy can result in considerable maternal and foetal adverse outcomes. Production of extended-spectrum beta-lactamase (ESBL) is a major antibiotic resistance mechanism by Enterobacteriaceae. OBJECTIVES:To determine the global preval...

journal_title：International journal of clinical practice

authors： Mansouri F,Sheibani H,Javedani Masroor M,Afsharian M

更新日期：2019-09-18 00:00:00

abstract：OBJECTIVE:The impacts of renin-angiotensin system (RAS)-targeting antihypertensive drugs on Alzheimer's disease (AD) remain controversial. We performed this meta-analysis to evaluate the precise value of RAS-targeting antihypertensive drugs in terms of attenuating incidence of AD and slowing down cognitive decline in p...

journal_title：International journal of clinical practice

authors： Ye R,Hu Y,Yao A,Yang Y,Shi Y,Jiang Y,Zhang J

更新日期：2015-06-01 00:00:00

abstract：:Gastric acid is pathogenic in many gastrointestinal disorders, such as gastroesophageal reflux disease and peptic ulcer disease. Proton pump inhibitors (PPIs) are the antisecretory drugs of choice for serious acid-related conditions. Ample recent data exist to explicate virtually every aspect of the clinical managemen...

journal_title：International journal of clinical practice

authors： Robinson M

更新日期：2005-06-01 00:00:00

abstract：:Despite differences in design, many large epidemiological studies using well-powered multivariate analyses consistently provide overwhelming evidence of a link between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Preclinical evidence suggests that several common pathophysiological mechanisms are ...

journal_title：International journal of clinical practice

authors： Kirby M,Chapple C,Jackson G,Eardley I,Edwards D,Hackett G,Ralph D,Rees J,Speakman M,Spinks J,Wylie K

更新日期：2013-07-01 00:00:00

abstract：:Osteoporosis results from a decrease in bone strength yielding increased susceptibility to fractures. Hip and spine fractures are a major cause of morbidity and mortality in the elderly population. With an increasingly ageing world population, early prevention of bone loss is essential for adequate control of this con...

journal_title：International journal of clinical practice

authors： Reginster JY,Malaise O,Neuprez A,Bruyere O

更新日期：2007-02-01 00:00:00

abstract：:Influences on bladder health begin during infancy and continue throughout the lifespan. Bladder anatomy and physiology change as individuals age, and the risk and propensity for bladder conditions, including lower urinary tract symptoms, throughout life are related to factors specific to age, sex, and life events. Bla...

journal_title：International journal of clinical practice

authors： Ellsworth P,Marschall-Kehrel D,King S,Lukacz E

更新日期：2013-05-01 00:00:00