The current management of cystic fibrosis.

abstract：BACKGROUND:Complementary medicine and alternative approaches to chronic and intractable health conditions are increasingly being used, and require critical evaluation. OBJECTIVE:The aim of this review was to systematically evaluate available evidence for the effectiveness and safety of instruction in the Alexander Tec...

journal_title：International journal of clinical practice

authors： Woodman JP,Moore NR

更新日期：2012-01-01 00:00:00

abstract：:Pharmacological treatment of hypertension represents a cost-effective way for preventing cardiovascular and renal complications. To benefit maximally from antihypertensive treatment blood pressure (BP) should be brought to below 140/90 mmHg in every hypertensive patient, and even lower (< 130/80 mmHg) if diabetes or r...

journal_title：International journal of clinical practice

authors： Struijker-Boudier HA,Ambrosioni E,Holzgreve H,Laurent S,Mancia G,Ruilope LM,Waeber B

更新日期：2007-09-01 00:00:00

abstract：:Aortic valve disease is common and has significant impact on prognosis and quality of life. In this educational review, we cover the pathophysiology, presentation and assessment of aortic stenosis (AS) and aortic regurgitation (AR), including the role of imaging modalities beyond echocardiography. We review current tr...

journal_title：International journal of clinical practice

authors： Rayner J,Coffey S,Newton J,Prendergast BD

更新日期：2014-10-01 00:00:00

abstract：AIMS:To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive and anabolic osteoporosis treatments. METHODS:Published papers related to the mechanism of action of approved osteoporosis treatments were sought through MEDLINE searches. FINDINGS:Osteoporot...

journal_title：International journal of clinical practice

authors： Hanley DA,Adachi JD,Bell A,Brown V

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To test whether parathyroid hormone (PTH) might be related to the development of atherosclerosis in postmenopausal women, we measured serum levels of PTH, the carotid intima-media thickness (IMT), and other clinical and biochemical parameters. METHODS:One hundred and seven postmenopausal women were recruite...

journal_title：International journal of clinical practice

authors： Choi HS,Kim SH,Rhee Y,Cho MA,Lee EJ,Lim SK

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:DPP-4 inhibitors (DPP4-I) have been shown to provide non-inferior glycaemic control compared with sulfonylureas (SU), but result in a reduction of body weight and a significantly lower risk of hypoglycaemia in patients with type 2 diabetes. We aimed to validate these results in a large real-world sample of p...

journal_title：International journal of clinical practice

authors： Gitt AK,Bramlage P,Binz C,Krekler M,Deeg E,Tschöpe D

更新日期：2013-10-01 00:00:00

abstract：:The purpose of this survey was to ascertain which physiotherapy techniques are currently used, how interventions are assessed and to determine the views of physiotherapists in the UK on the need for further research. Senior physiotherapists in 100 randomly selected hospitals providing respiratory care in the UK were s...

journal_title：International journal of clinical practice

authors： O'Neill B,Bradley JM,McArdle N,MacMahon J

更新日期：2002-01-01 00:00:00

abstract：:Twin reversed arterial perfusion (TRAP) syndrome is an extremely rare manifestation of feto-fetal transfusion syndrome. This condition is seen in monozygotic twin pregnancies, where the affected twin is perfused retrogradely by the healthy twin. The affected twin presents with bizarre malformations such as acardia and...

journal_title：International journal of clinical practice

authors： Sen S,Esen UI,Sturgiss SN

更新日期：2002-12-01 00:00:00

abstract：:There is substantial evidence that many patients with impaired left ventricular function secondary to coronary artery disease may have hibernating or stunned myocardium. The identification of these patients is important, as revascularisation is associated with an improvement in function, and there is some evidence tha...

journal_title：International journal of clinical practice

authors： Redwood SR,Ferrari R,Marber MS

更新日期：1998-06-01 00:00:00

abstract：:A retrospective audit of (99m)Tc-HMPAO SPECT scans was undertaken to assess the utility of brain perfusion imaging in a cohort of young cognitively impaired patients in whom diagnostic uncertainty remained after standard clinical and neuropsychological assessment and structural brain imaging. SPECT scans were assessed...

journal_title：International journal of clinical practice

authors： Doran M,Vinjamuri S,Collins J,Parker D,Larner AJ

更新日期：2005-04-01 00:00:00

abstract：:A high prevalence of newly detected diabetes mellitus (DM) and impaired glucose tolerance (IGT) has been reported in patients with acute myocardial infarction (AMI) and no previous diagnosis of DM. However, the prevalence of newly detected DM is grossly underestimated by using fasting plasma glucose (FPG). We determin...

journal_title：International journal of clinical practice

authors： Jessani S,Gangopadhyay K,Patel JV,Lip GY,Millane T

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to describe the occurrence, angulation and mesialisation ratio of the ectopic eruption of the maxillary permanent first molar (PFM) and its correlation with the pathological resorption of maxillary primary second molar (PSM). METHODS:This retrospective study was performed using the ...

journal_title：International journal of clinical practice

authors： Caliskan S,Tuloglu N,Ozdemir C,Kizilaslan S,Bayrak S

更新日期：2020-12-07 00:00:00

abstract：:Objectives:  The purpose of this updated meta-analysis was to determine whether exercise training reversed left ventricular remodelling in heart failure patients. Methods:  Articles were searched in MEDLINE, Cochrane Central Register of Controlled Trials, CINAHL, EMBASE and PubMed (up until October, 2011). The anti-re...

journal_title：International journal of clinical practice

authors： Chen YM,Li ZB,Zhu M,Cao YM

更新日期：2012-08-01 00:00:00

abstract：:It is important for primary care physicians to recognise rheumatoid arthritis and systemic lupus erythematosus patients as high-risk groups for atherosclerosis, requiring aggressive risk-factor modification. Recent studies suggest that this increased risk is not explained by an excess of traditional risk factors, but ...

journal_title：International journal of clinical practice

authors： Farzaneh-Far A,Roman MJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Inappropriate drug prescribing has increased especially in developing countries where systems for monitoring medicine use are not well developed. This increases the rate of antimicrobial resistance. The study aim was to assess the prescribing patterns among urban primary health facilities in Botswan...

journal_title：International journal of clinical practice

authors： Mashalla Y,Setlhare V,Massele A,Sepako E,Tiroyakgosi C,Kgatlwane J,Chuma M,Godman B

更新日期：2017-12-01 00:00:00

abstract：:Tissue inflammation has been linked to cancer in several disease models. We tested the association between chronic inflammation and prostate cancer (PCa), as well as high-grade prostatic intraepithelial neoplasia (HGPIN), in prostatic needle biopsy specimens. Tissues from 4526 men, who underwent systematic ultrasound-...

journal_title：International journal of clinical practice

authors： Karakiewicz PI,Benayoun S,Bégin LR,Duclos A,Valiquette L,McCormack M,Bénard F,Saad F,Perrotte P

更新日期：2007-03-01 00:00:00

abstract：:Paliperidone, the 9-hydroxy metabolite of risperidone, was approved on 20 December, 2006 by the US Food and Drug Administration for the treatment of schizophrenia. It is also being tested for the treatment of bipolar mania. An on-line query of http://www.pubmed.gov and http://www.clinicaltrials.gov for 'paliperidone' ...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2007-04-01 00:00:00

abstract：:This case report describes a patient who presented with pyrexia of unknown origin allied with hypertriglyceridaemia (16.2 mmol/l) but not hypercholesterolaemia (4.1 mmol/l). Investigations identified the cause of the pyrexia as an adult T-cell lymphoma of natural killer cell phenotype (CD3[+], CD7[+], anti-TCR alpha/b...

journal_title：International journal of clinical practice

authors： Suryanarayanan S,Wierzbicki AS,Carr R,Ritter JM

更新日期：2003-12-01 00:00:00

abstract：:Obesity is the major risk factor for the development of hypertension. This association accentuates the risk of cardiovascular disease, as it is frequently accompanied by the components of the metabolic syndrome. This randomised open parallel study evaluated the chronic effects of moxonidine--a selective imidazoline re...

journal_title：International journal of clinical practice

authors： Sanjuliani AF,de Abreu VG,Francischetti EA

更新日期：2006-05-01 00:00:00

abstract：:This randomised, double-blind study compared the anti-hypertensive efficacy and tolerability of Candesartan cilexetil (CC 8-16 mg) and Amlodipine (AML 5-10 mg) on home blood pressure (HBP) measurements in mild-to-moderate hypertensive patients. After a 2-week wash-out, patients aged 18-74 years, with a sitting diastol...

journal_title：International journal of clinical practice

authors： Imbs JL,Nisse-Durgeat S,French Collaborative Candesartan Study Group.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Upper gastrointestinal (UGI) haemorrhage is a frequent cause of hospital admission. Scoring systems have been devised to identify those at risk of adverse outcomes. We evaluated the Glasgow Blatchford score's (GBS) ability to identify the need for clinical and endoscopic intervention in patients with UGI hae...

journal_title：International journal of clinical practice

authors： Srirajaskanthan R,Conn R,Bulwer C,Irving P

更新日期：2010-06-01 00:00:00

abstract：:Asthma treatment is suboptimal in many patients, with impacts on morbidity and mortality, healthcare resource utilisation and patients' quality of life. The reasons for this include the inherent variability of asthma and the unpredictability of exacerbations, which can range from mild to fatal. In addition, asthma can...

journal_title：International journal of clinical practice

authors： Gillissen A

更新日期：2004-06-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with gastrointestinal adverse effects, ranging from dyspepsia and peptic ulcer disease to more serious complications such as haemorrhage or perforation. NSAID-induced gastrointestinal toxicity is a significant medical problem worldwide. Misoprostol is effec...

journal_title：International journal of clinical practice

authors： Singh G,Triadafilopoulos G

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:This study aimed to determine the prevalence of gout in a general Turkish population, according to the American College of Rheumatology (Wallace) criteria proposed for gout classification. METHODS:This study was conducted in two districts of Izmir Province in Turkey, and involved 2835 subjects of ≥ 20 years...

journal_title：International journal of clinical practice

authors： Birlik M,Gurler O,Akar S,Sari I,Onen F,Akkoc N

更新日期：2014-06-01 00:00:00

abstract：:This open multicentre study compared the efficacy and tolerability of clarithromycin and spiramycin in the treatment of lower respiratory tract infections in Brazil and Colombia. A total of 125 patients with a clinical and radiological diagnosis of pneumonia, acute bronchitis or exacerbation of chronic bronchitis were...

journal_title：International journal of clinical practice

authors： Rocha RT,Awad CE,Ali A,Matyas R,Vital AC,Silva CO,Dainesi SM,Salazar MS,Nakatani J

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:The high prevalence of both hypovitaminosis D and type 2 diabetes (T2DM) in the Asian community is well recognised, but the impact of diabetes on vitamin D status and vice versa, has not been well reported. AIMS:To determine the prevalence of hypovitaminosis D in Asian patients with T2DM and its impact on g...

journal_title：International journal of clinical practice

authors： Tahrani AA,Ball A,Shepherd L,Rahim A,Jones AF,Bates A

更新日期：2010-02-01 00:00:00

abstract：:Systolic heart failure (SHF) is associated with increased morbidity and mortality. Beta-blockers (BB) were shown to provide mortality benefit in patients with SHF, and currently indicated in all stages of patients with SHF. We evaluated the factors influencing the prescription of BBs at discharge in patients hospitali...

journal_title：International journal of clinical practice

authors： Yilmaz MB,Refiker M,Guray Y,Guray U,Altay H,Demirkan B,Caldir V,Korkmaz S

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To assess the relationship between high-definition optical coherence tomography (HD-OCT) and scanning laser polarimetry (SLP) with variable (VCC) and enhanced (ECC) corneal compensation in measuring peripapillary retinal nerve fibre layer (RNFL) thickness in healthy eyes and those with early-to-moderate glaucom...

journal_title：International journal of clinical practice

authors： Benítez-del-Castillo J,Martinez A,Regi T

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Opioid-induced constipation can have a major negative impact on patients' quality of life. This randomised clinical trial evaluated patient assessment of the efficacy and tolerability of oral prolonged-release (PR) oxycodone when co-administered with oral naloxone PR. METHODS:Two hundred and ...

journal_title：International journal of clinical practice

authors： Nadstawek J,Leyendecker P,Hopp M,Ruckes C,Wirz S,Fleischer W,Reimer K

更新日期：2008-08-01 00:00:00

abstract：IMPORTANCE:There is an ever-increasing drive to improve surgical patient outcomes. Given the benefits which robotics has bestowed upon a wide range of industries, from vehicle manufacturing to space exploration, robots have been highlighted by many as essential for continued improvements in surgery. OBJECTIVE:The goal...

journal_title：International journal of clinical practice

authors： Hussain A,Malik A,Halim MU,Ali AM

更新日期：2014-11-01 00:00:00