Appropriate choice of proton pump inhibitor therapy in the prevention and management of NSAID-related gastrointestinal damage.

abstract：BACKGROUND:The association between testosterone deficiency and insulin resistance in men with type 2 diabetes is well established. Current Endocrine Society and European Association of Urology guidelines recommend the measurement of testosterone levels in all men with type 2 diabetes and in men suffering from erectile ...

journal_title：International journal of clinical practice

authors： Hackett G,Cole N,Bhartia M,Kennedy D,Raju J,Wilkinson P,Saghir A,Blast Study Group.

更新日期：2014-02-01 00:00:00

abstract：:Patients with severely increased blood pressure often present to the emergency department. Rapid lowering of blood pressure can precipitate or worsen end organ damage. We report two cases that developed cerebrovascular and cardiovascular adverse events associated with aggressive treatment of increased blood pressure b...

journal_title：International journal of clinical practice

authors： Yanturali S,Akay S,Ayrik C,Cevik AA

更新日期：2004-05-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Persistence with antimuscarinic (AM) drugs prescribed for overactive bladder (OAB) is poor. This study aimed to compare persistence and adherence with the beta-3-adrenoceptor agonist mirabegron (MIR) vs AMs over 12 months. PATIENTS AND METHODS:This retrospective cohort analysis included pat...

journal_title：International journal of clinical practice

authors： Wagg AS,Foley S,Peters J,Nazir J,Kool-Houweling L,Scrine L

更新日期：2017-10-01 00:00:00

abstract：INTRODUCTION:Niacin is underutilised because of flushing. Lack of a quantitative tool to assess niacin-induced flushing has precluded the objective evaluation of flushing associated with extended-release (ER) niacin formulations. We developed the Flushing Symptom Questionnaire((c)) (FSQ), a quantitative tool to assess ...

journal_title：International journal of clinical practice

authors： Paolini JF,Mitchel YB,Reyes R,Thompson-Bell S,Yu Q,Lai E,Watson DJ,Norquist JM,Sisk CM,Bays HE

更新日期：2008-06-01 00:00:00

abstract：:Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and humans. The reduced form of ZEN, α-ZEA...

journal_title：International journal of clinical practice

authors： Pazaiti A,Kontos M,Fentiman IS

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In late December 2019 and on 1st January 2020, the coronavirus (COVID-19) infecting humans was first identified in Wuhan, Hubei Province, China. Later cases have also been confirmed worldwide. Coronaviruses are RNA viruses that are phenotypically and genotypically diverse. Globally, as of 6th April 2020, lab...

journal_title：International journal of clinical practice

authors： Almaghaslah D,Kandasamy G,Almanasef M,Vasudevan R,Chandramohan S

更新日期：2020-11-01 00:00:00

abstract：:The use of hormone replacement therapy (HRT) for cardiovascular risk reduction remains uncertain. Although previous epidemiological surveys have suggested a clear benefit and nearly 50% mortality risk reduction with HRT in postmenopausal women, recent randomised trials have largely failed to support this. The epidemio...

journal_title：International journal of clinical practice

authors： Chin BS,Futaba K,Jethwa A,Lip GY

更新日期：2001-10-01 00:00:00

abstract：AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...

journal_title：International journal of clinical practice

authors： Drake MJ,MacDiarmid S,Chapple CR,Esen A,Athanasiou S,Cambronero Santos J,Mitcheson D,Herschorn S,Siddiqui E,Huang M,Stoelzel M

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:This review examines the available data on the efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) for treating the commonly missed climacteric symptoms of menopause. DISCUSSION:Although some women may pass through the menopausal transition phas...

journal_title：International journal of clinical practice

authors： Warren MP

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Emerging research demonstrates an interrelationship between systemic inflammation, physical activity and premature all-cause mortality among chronic obstructive pulmonary disease (COPD) patients. Less common in this literature is the use of objective measures of physical activity and representative samples o...

journal_title：International journal of clinical practice

authors： Loprinzi PD,Walker JF

更新日期：2016-03-01 00:00:00

abstract：:Indiplon is a novel non-benzodiazepine sedative-hypnotic that modulates the GABAA receptor complex. It appears to be more selective for the alpha1-receptor subunit, associated with sedation, than other hypnotics. Two different formulations of indiplon have been developed: an immediate release (IR) version targeting sl...

journal_title：International journal of clinical practice

authors： Lankford A,Ancoli-Israel S

更新日期：2007-06-01 00:00:00

abstract：:The clinical syndrome of anaphylaxis and anaphylactoid reactions is quite variable, making diagnosis difficult at times. Early recognition by patient or physician is imperative to appropriate management. Recurrences may be life-threatening if the initial diagnosis is incorrect, as patients do not avoid the offending a...

journal_title：International journal of clinical practice

authors： Murrant T,Bihari D

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Over the last two decades the interest on patent foramen ovale (PFO) as a cause of cardioembolism in cryptogenic stroke has tremendously increased, thanks to the availability of better techniques to diagnose cardiac right-to-left shunt by ultrasounds and of percutaneous means of PFO treatment with interventi...

journal_title：International journal of clinical practice

authors： Savino K,Maiello M,Pelliccia F,Ambrosio G,Palmiero P

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Assess and categorise the available prevalence data on coexistent LUTS and ED in the general population and among individuals consulting a healthcare provider for any reason or when seeking treatment for LUTS and/or ED. METHODS:Literature search of English-language articles published during the last 15 years...

journal_title：International journal of clinical practice

authors： Seftel AD,de la Rosette J,Birt J,Porter V,Zarotsky V,Viktrup L

更新日期：2013-01-01 00:00:00

abstract：:Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...

journal_title：International journal of clinical practice

authors： Demirel F,Bideci A,Camurdan MO,Cinaz P

更新日期：2007-08-01 00:00:00

abstract：:The potential effect of orlistat on cardiovascular co-morbidities may have been previously underestimated. This study assesses the efficacy of orlistat therapy for weight loss and cardiovascular risk factor reduction in obese patients with cardiovascular risk. This was a 54-week, double-blind, randomised, placebo-cont...

journal_title：International journal of clinical practice

authors： Broom I,Wilding J,Stott P,Myers N,UK Multimorbidity Study Group.

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:Vardenafil has demonstrated efficacy for the pharmacological management of erectile dysfunction (ED). Accumulating evidence suggests that ED is frequently associated with underlying cardiovascular and metabolic conditions which are thought to be involved in the aetiology of ED. The present review aims to summ...

journal_title：International journal of clinical practice

authors： Eardley I,Lee JC,Guay AT

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Cariprazine is an oral antipsychotic approved in the US for the treatment of schizophrenia, acute bipolar mania, and most recently, bipolar depression. The aim of this systematic review is to describe the efficacy, tolerability and safety of cariprazine for the treatment of depressive episodes associated with...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2019-10-01 00:00:00

abstract：:Acute pulmonary oedema can sometimes complicate adenotonsillectomy carried out for obstructive sleep apnoea. Early recognition and adequate oxygenation are the key to management. We report such a case; the pathophysiology and management of this rare complication of a common procedure are discussed. ...

journal_title：International journal of clinical practice

authors： Motamed M,Djazaeri B,Marks R

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Temporomandibular disorders (TMD) are the most common orofacial impairment, but the relevance of certain clinical features in TMD is not clear. OBJECTIVE:The main objective of this study was to analyse if temporomandibular disorders (TMD) are associated with sociodemographic (eg age, height, weight, body ma...

journal_title：International journal of clinical practice

authors： Delgado-Delgado R,Iriarte-Álvarez N,Valera-Calero JA,Centenera-Centenera MB,Garnacho-Garnacho VE,Gallego-Sendarrubias GM

更新日期：2021-01-02 00:00:00

abstract：AIMS:To evaluate in a real-world setting the effectiveness of exenatide once-weekly (ExQW) in patients with T2D and to determine predictors of glycaemic and weight response to this drug at 6 months. METHODS:Observational, retrospective, multicenter study in adult patients with T2D and BMI ≥30 kg/m2 from 4 tertiary Spa...

journal_title：International journal of clinical practice

authors： Gorgojo-Martínez JJ,Gargallo-Fernández MA,Brito-Sanfiel M,Lisbona-Catalán A

更新日期：2018-03-01 00:00:00

abstract：:The aim was to evaluate 24 hr urine catecholamine, HMMA and HVA excretion in relation to ploidy in phaeochromocytoma. Data from five diploid and nine tetraploid tumours showed a significant reduction in urine noradrenaline (p = 0.02) and HMMA (p = 0.03) in diploid tumours but no difference in adrenaline, dopamine and ...

journal_title：International journal of clinical practice

authors： Tormey WP,Fitzgerald RJ,Thomas G,Kay EW,Leader MB

更新日期：2000-10-01 00:00:00

abstract：:The following article reviews treatment for acne vulgaris. Selection of therapy should be based on clinical appearance taking into account lesion type and severity, as well as identification of acne scarring and the psychosocial disability caused by the disease. ...

journal_title：International journal of clinical practice

authors： Layton AM

更新日期：2006-01-01 00:00:00

abstract：AIMS:Strong evidence indicates that drugs reduce blood lipids and improve cardiovascular end-points, leading to their wide usage. However, the success of these drugs can be affected by poor patient's adherence to prescribed medication. This study aimed to evaluate medication adherence in patients with dyslipidaemia in ...

journal_title：International journal of clinical practice

authors： Shakarneh JK,Hallak HO,Awadallah HB,Al-Hamed DH,Khdour MR

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, followin...

journal_title：International journal of clinical practice

authors： Jun L,Yuguo C,Zhiguo W,Jinfeng L,Huawei M,Xiuhua L,Yonggui Z,Yanhua X,Kong Y,Hongtao L,Yuliang Z

更新日期：2013-10-01 00:00:00

abstract：AIMS:Our goal was to determine the effect of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) consensus algorithm for the initiation and adjustment of type 2 diabetes (T2D) therapy, published in 2006, on the incidence of early metformin monotherapy (EMM), defined as ...

journal_title：International journal of clinical practice

authors： Huang EA,Zdon GS,Moore RJ,Jane Moran H,Quick WW

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Medication errors are a frequent cause of adverse drug events and a major concern for patient safety. This study compared the predictors of error among seven countries (Australia, Canada, New Zealand, the United Kingdom, the United States, Germany and the Netherlands). METHODS:We conducted a cross-sectional ...

journal_title：International journal of clinical practice

authors： Lu CY,Roughead E

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Maternal responsiveness seems to be necessary for a child to develop a safe attachment. However, even after many years of research on maternal responsiveness, only a few attempts have been made to find ways of promoting mother and child interaction. This study aimed at determining the association between mat...

journal_title：International journal of clinical practice

authors： Abuhammad S

更新日期：2021-01-23 00:00:00

abstract：AIMS:Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out 6 years earli...

journal_title：International journal of clinical practice

authors： Molero JM,Moragas A,González López-Valcárcel B,Bjerrum L,Cots JM,Llor C

更新日期：2019-05-01 00:00:00

abstract：AIM:Real-life studies are needed to confirm the clinical relevance of findings from randomised controlled trials (RCTs). This study aimed to assess the effectiveness and tolerability of vildagliptin add-on vs. other oral antihyperglycaemic drugs (OADs) added to OAD monotherapy in a real-life setting, and to explore the...

journal_title：International journal of clinical practice

authors： Mathieu C,Barnett AH,Brath H,Conget I,de Castro JJ,Göke R,Márquez Rodriguez E,Nilsson PM,Pagkalos E,Penfornis A,Schaper NC,Wangnoo SK,Kothny W,Bader G

更新日期：2013-10-01 00:00:00