Measuring flushing symptoms with extended-release niacin using the flushing symptom questionnaire: results from a randomised placebo-controlled clinical trial.

abstract：AIMS:We prospectively enrolled 207 patients (121 were 75 or older and 86 younger than 75) who were admitted to three Respiratory Monitoring Units. The primary outcomes were intubation and mortality rates; the secondary outcomes were changes in arterial blood gases analysis, non-invasive ventilation (NIV) duration and l...

journal_title：International journal of clinical practice

authors： Nicolini A,Santo M,Ferrera L,Ferrari-Bravo M,Barlascini C,Perazzo A

更新日期：2014-12-01 00:00:00

abstract：AIM:To evaluate whether administration of long-acting basal insulin analogue plus oral antidiabetic drugs (OADs) improves glycaemic control in type 2 diabetic patients with glycosylated haemoglobin (HbA1c) > 7% (53 mmol/mol) under premixed insulin therapy. METHODS:This is a multicentre, observational, retrospective st...

journal_title：International journal of clinical practice

authors： Gómez-Peralta F,Carramiñana-Barrera F,Félix-Redondo FJ,Fraile-Gómez J,Extreme Rescue Study Group.

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Cutaneous leishmaniasis (CL) is a skin disease characterised by prolonged nodulo-ulcerative lesions of the skin that heals with atrophic scar. Clinical features of CL vary depending on the type of parasite and host immune resistance. The aim of this study was to investigate the clinical features of atypical a...

journal_title：International journal of clinical practice

authors： An I,Aksoy M,Ozturk M,Ayhan E,Erat T,Yentur Doni N,Guldur ME

更新日期：2020-10-26 00:00:00

abstract：:The diagnosis of acute renal infarction (ARI) is often delayed or unrecognised because of its non-specific presentation and the rarity of the disease. We evaluated the clinical presentations, laboratory findings, underlying medical conditions and treatment of 18 Chinese patients with ARI who presented to the emergency...

journal_title：International journal of clinical practice

authors： Tsai SH,Chu SJ,Chen SJ,Fan YM,Chang WC,Wu CP,Hsu CW

更新日期：2007-01-01 00:00:00

abstract：AIM:Infection is a major cause of increased mortality after a liver transplant (LT). This study sought to identify the incidence, prevalence and risk factors of microbial infection for recipients who underwent LT using grafts from donors after cardiac death (DCD). METHODS:We retrospectively analysed the frequency and ...

journal_title：International journal of clinical practice

authors： Zhang ML,Xu J,Zhang W,Liu XY,Zhang M,Wang WL,Zheng SS

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The decision on whether or not to treat a first seizure is dependent on several medical and non-medical factors. AIMS:In this review, we have summarised the important aspects that determine the advantages and disadvantages of treating a first seizure. We have looked at evidence from randomised controlled tr...

journal_title：International journal of clinical practice

authors： Sathasivam S,Nicolson A

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:To evaluate state and trait form of anxiety and current depression in patients affected by gastrointestinal diseases. METHODS:We studied 1641 outpatients with gastrointestinal disorders, consecutively referred to our Internal Medicine outpatients from 1997 to 2005. State and trait anxiety were assessed by t...

journal_title：International journal of clinical practice

authors： Addolorato G,Mirijello A,D'Angelo C,Leggio L,Ferrulli A,Abenavoli L,Vonghia L,Cardone S,Leso V,Cossari A,Capristo E,Gasbarrini G

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Although mild asthmatics form the majority of asthma sufferers, there is a relative paucity of evidence-based treatment compared with severe asthmatics. OBJECTIVE:We have performed an up-to-date review of the literature on therapy in this group of patients who form an overlooked but important majority. Pote...

journal_title：International journal of clinical practice

authors： Koh MS,Irving LB

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:The influence of cardiovascular risk factors/comorbidities on response to oral once-daily tadalafil 5 mg was explored in men with lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH). METHODS:This post hoc analysis pooled data from four double-blind studies in which 1498 men wit...

journal_title：International journal of clinical practice

authors： Vlachopoulos C,Oelke M,Maggi M,Mulhall JP,Rosenberg MT,Brock GB,Esler A,Büttner H

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Mobile smart phones have become increasingly integrated into the practice of doctors and allied medical professionals. Recent studies suggest them to represent reservoirs for pathogens with potential to cause nosocomial infections. This study aimed to investigate the level of contamination on phones used on ...

journal_title：International journal of clinical practice

authors： Mark D,Leonard C,Breen H,Graydon R,O'Gorman C,Kirk S

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, followin...

journal_title：International journal of clinical practice

authors： Jun L,Yuguo C,Zhiguo W,Jinfeng L,Huawei M,Xiuhua L,Yonggui Z,Yanhua X,Kong Y,Hongtao L,Yuliang Z

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promising results in the treatment of type 2 diabetes. Herein, we compared the efficacy and safety of once-weekly GLP-1RAs with exenatide and liraglutide separately. METHODS:We systematically surveyed the pertinent literature using ...

journal_title：International journal of clinical practice

authors： Xue X,Ren Z,Zhang A,Yang Q,Zhang W,Liu F

更新日期：2016-08-01 00:00:00

abstract：:A case is presented of a patient who described a koro-like syndrome related to amfetamine use; this consisted of a perception that his penis had reduced in size and was at risk of being sucked into his body. He described this as Whizz-Dick. This condition was also reported independently by amfetamine users attending a...

journal_title：International journal of clinical practice

authors： Bloor RN

更新日期：2004-07-01 00:00:00

abstract：:The Surgical Nutrition Advisory Team (SNAT) of our hospital, formed in October 1992, decided to study the impact of such a team on the six months before and after its formation on catheter care and nutritional support in total parenteral nutrition. Our study showed that with a dedicated nutritional team, catheter seps...

journal_title：International journal of clinical practice

authors： Png DJ,Ong CL,Chan S

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Although the relationship of elevated serum uric acid levels and cardiovascular disease has been established in a great number of studies, the causal relevance of this finding remains ambiguous. An approach to evaluate the causal relevance of biomarkers is to exploit the natural randomised allocation of alle...

journal_title：International journal of clinical practice

authors： Kei A,Koutsouka F,Makri A,Elisaf M

更新日期：2018-01-01 00:00:00

abstract：:Current therapy in Russia for long-term management of asthma is mainly non-steroidal. This provided the opportunity to compare the efficacy and safety of formoterol (Oxis) Turbuhaler plus budesonide (Pulmicort) Turbuhaler with budesonide Turbuhaler alone in adults (n=338) with mild to moderate asthma who had little pr...

journal_title：International journal of clinical practice

authors： Chuchalin AG,Ovcharenko SI,Goriachkina LA,Sidorenko IV,Tsoi AN,Epoch Study Group.

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Effective and efficient communication is crucial in healthcare. Written communication remains the most prevalent form of communication between specialised and primary care. We aimed at reviewing the literature on the quality of written communication, the impact of communication inefficiencies and recommendat...

journal_title：International journal of clinical practice

authors： Vermeir P,Vandijck D,Degroote S,Peleman R,Verhaeghe R,Mortier E,Hallaert G,Van Daele S,Buylaert W,Vogelaers D

更新日期：2015-11-01 00:00:00

abstract：:A 43-year-old female patient with Basedow-Graves' disease developed agranulocytosis in the eighth month of propylthiouracil therapy. After discontinuing the drug, a broad spectrum antibiotic regimen plus recombinant human granulocyte colony-stimulating factor (G-CSF), a human haematopoietic growth factor, were started...

journal_title：International journal of clinical practice

authors： Altunbas H,Yazicioglu G,Balci MK,Karayalçin U,Undar L

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Chronic pelvic pain (CPP) is a common and complex disease whose cause is often clinically inexplicable, with consequent difficulty in diagnosis and treatment. Patients with CPP have high levels of anxiety and depression, with a consequent impairment of their quality of life. AIMS:The objective of this study...

journal_title：International journal of clinical practice

authors： Romão AP,Gorayeb R,Romão GS,Poli-Neto OB,dos Reis FJ,Rosa-e-Silva JC,Nogueira AA

更新日期：2009-05-01 00:00:00

abstract：AIMS:The aim of this study was to assess patient characteristics, medication treatment patterns and healthcare resource utilization among men with existing erectile dysfunction (ED) or benign prostatic hyperplasia (BPH), who are newly diagnosed with the second condition (BPH or ED) compared with those with only one con...

journal_title：International journal of clinical practice

authors： Ilo D,Raluy-Callado M,Graham-Clarke P,Sadasivan R,Birt J,Donaldson R,Zhu E,Kirby MG,Neasham D

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:The current review describes how the health status profile of people with fibromyalgia (FM) compares to that of people in the general population and patients with other health conditions. METHODS:A review of 37 studies of FM that measured health status with the 36-item Medical Outcomes Study Short-Form Healt...

journal_title：International journal of clinical practice

authors： Hoffman DL,Dukes EM

更新日期：2008-01-01 00:00:00

abstract：:The clinical syndrome of anaphylaxis and anaphylactoid reactions is quite variable, making diagnosis difficult at times. Early recognition by patient or physician is imperative to appropriate management. Recurrences may be life-threatening if the initial diagnosis is incorrect, as patients do not avoid the offending a...

journal_title：International journal of clinical practice

authors： Murrant T,Bihari D

更新日期：2000-06-01 00:00:00

abstract：:Obesity is the major risk factor for the development of hypertension. This association accentuates the risk of cardiovascular disease, as it is frequently accompanied by the components of the metabolic syndrome. This randomised open parallel study evaluated the chronic effects of moxonidine--a selective imidazoline re...

journal_title：International journal of clinical practice

authors： Sanjuliani AF,de Abreu VG,Francischetti EA

更新日期：2006-05-01 00:00:00

abstract：:The current study compared the effectiveness of the graduated tuning fork (128 Hz) and the neurothesiometer in assessing vibration sensation perception in patients presenting with type II diabetes mellitus. A quota sample of patients (n = 21; age range 43-73 years) were assessed using the neurothesiometer and tuning f...

journal_title：International journal of clinical practice

authors： O'Neill J,McCann SM,Lagan KM

更新日期：2006-02-01 00:00:00

abstract：:An increasing number of patients aged>or=70 years are presenting for elective non-cardiac surgery. We undertook this study to: (i) compare the nature and distribution of cardiovascular disease (CVD) risk factors in an at risk population of patients aged>or=70 years undergoing elective surgery compared with a younger a...

journal_title：International journal of clinical practice

authors： Naughton C,Feneck RO

更新日期：2007-05-01 00:00:00

abstract：AIMS:To analyse the predictive capacity of 15 machine learning methods for estimating cardiovascular risk in a cohort and to compare them with other risk scales. METHODS:We calculated cardiovascular risk by means of 15 machine-learning methods and using the SCORE and REGICOR scales and in 38 527 patients in the Spanis...

journal_title：International journal of clinical practice

authors： Quesada JA,Lopez-Pineda A,Gil-Guillén VF,Durazo-Arvizu R,Orozco-Beltrán D,López-Domenech A,Carratalá-Munuera C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:There has been a dramatic increase in the incidence of immediate breast reconstruction after mastectomy for breast cancer over the past few decades and autologous tissue flaps are being used with increasing frequency. Concern has been expressed that these complex procedures may lead to a delay in the deliver...

journal_title：International journal of clinical practice

authors： Lewis RS,Kontos M

更新日期：2009-11-01 00:00:00

abstract：:Urea is a major component of many daily skincare products which is widely used. Its role in the treatment of, for example atopic skin, atopic eczema, psoriasis and ichthyosis, is undisputed. However, the mode of action of urea is partly still elusive and goes far beyond its assumed passive role. This article shall elu...

journal_title：International journal of clinical practice

authors： Dirschka T

更新日期：2020-12-01 00:00:00

abstract：:We sought to clarify whether impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or both (IFG/IGT) represent the most severe impairment in insulin resistance (IR) and insulin secretion. Among the 159 Chinese subjects, 21 were diagnosed as having IFG, 103 as having IGT and 35 as having both. IR and beta-ce...

journal_title：International journal of clinical practice

authors： Hsieh CH,Kuo SW,Hung YJ,Shen DC,Ho CT,Lian WC,Lee CH,Fan SC,Pei D

更新日期：2005-06-01 00:00:00

abstract：:Headache is frequently reported as one of the neurological manifestations of essential thrombocythaemia (ET) and other myeloproliferative neoplasms. It is associated with considerable morbidity; yet, it is a frequently under-recognised symptom. In patients with ET, headaches may be attributable to the disease, to the ...

journal_title：International journal of clinical practice

authors： Frewin R,Dowson A

更新日期：2012-10-01 00:00:00