Abstract:
OBJECTIVE:Assess and categorise the available prevalence data on coexistent LUTS and ED in the general population and among individuals consulting a healthcare provider for any reason or when seeking treatment for LUTS and/or ED. METHODS:Literature search of English-language articles published during the last 15 years. RESULTS:Of 23 relevant studies identified, 12 used both the International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF) as assessment tools and 11 used alternative approaches. In studies using both IPSS and IIEF, overall prevalence of coexistent LUTS/ED of any severity was not assessable for men in the general population, but rates ranged from 14-37% based on alternative assessments. In the general male population, 13-29% had moderate to severe LUTS and 8-35% had moderate to severe ED. In studies using both IPSS and IIEF, overall prevalence of coexistent LUTS and ED of any severity was 71-80% among men seeking treatment for LUTS, and 74% based on alternative assessments. Among men who sought treatment for either condition, 67-100% had moderate to severe LUTS and 43-59% had moderate to severe ED. Coexistence of LUTS and ED increased with age, ranging from 59-86% among men aged 40s to 60s in primary care to 79-100% in treatment-seeking men with LUTS aged 50s to 70s. Impact on QoL varied, but health-related QoL was generally worse in treatment-seeking men compared with men in the general population. CONCLUSIONS:Although less than one-third of middle-aged and older men in the general population have coexisting LUTS and ED, most men seeking treatment for either LUTS or ED have both conditions. Symptom severity and impact on QoL in each condition increase when LUTS and ED coexist.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Seftel AD,de la Rosette J,Birt J,Porter V,Zarotsky V,Viktrup Ldoi
10.1111/ijcp.12044subject
Has Abstractpub_date
2013-01-01 00:00:00pages
32-45issue
1eissn
1368-5031issn
1742-1241journal_volume
67pub_type
杂志文章,评审abstract:INTRODUCTION:The coexistence of diabetes mellitus (DM) and hypertension (HTN) worsens clinical outcomes and contributes to increased morbidity and mortality. OBJECTIVE:This study aims to analyse the length of stay and healthcare costs by calculating the direct and indirect costs of diabetes with coexisting hypertensio...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13990
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promising results in the treatment of type 2 diabetes. Herein, we compared the efficacy and safety of once-weekly GLP-1RAs with exenatide and liraglutide separately. METHODS:We systematically surveyed the pertinent literature using ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/ijcp.12847
更新日期:2016-08-01 00:00:00
abstract::An increasing number of patients aged>or=70 years are presenting for elective non-cardiac surgery. We undertook this study to: (i) compare the nature and distribution of cardiovascular disease (CVD) risk factors in an at risk population of patients aged>or=70 years undergoing elective surgery compared with a younger a...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01304.x
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Ultrasonography is increasingly used by clinicians to identify abdominal aortic aneurysms (AAA). We performed a systematic review and meta-analysis comparing the accuracy of non-radiologist performed ultrasound (NRPUS) for AAA disease to the 'gold standard' of radiologist performed aortic imaging (RPI), intr...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ijcp.12453
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:Vardenafil has demonstrated efficacy for the pharmacological management of erectile dysfunction (ED). Accumulating evidence suggests that ED is frequently associated with underlying cardiovascular and metabolic conditions which are thought to be involved in the aetiology of ED. The present review aims to summ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2008.01852.x
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES:In late July, Cyprus experienced the second epidemic wave of COVID-19. We present the steps taken by the government and evaluate their effect on epidemic trends. MATERIALS:Cyprus Press and Information Office data were analysed. Using an R-based forecasting program, two models were created to predict cases u...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13944
更新日期:2020-12-18 00:00:00
abstract:OBJECTIVE:The objective of this study was to investigate the relationship between the use of medicinal plants and medication adherence in elderly people. METHODS:Observational, cross-sectional study of elderly residents in Cuité-PB, Northeastern Brazil, through a household survey. A stratified proportional and systema...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12773
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND AND AIMS:Inappropriate drug prescribing has increased especially in developing countries where systems for monitoring medicine use are not well developed. This increases the rate of antimicrobial resistance. The study aim was to assess the prescribing patterns among urban primary health facilities in Botswan...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13042
更新日期:2017-12-01 00:00:00
abstract::The aim of this study was to assess the interventions by general practitioners on cardiovascular risk factors among persons without a history of cardiovascular disease attending for a cardiovascular check-up. All inhabitants of three Belgian towns aged between 45 and 64 years were invited for a cardiovascular check-up...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1368-5031.2004.0104.x
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:This study evaluates the effectiveness, safety and costs of switching to a rilpivirine/emtricitabine/tenofovir disoproxil fumarate (RPV/FTC/TDF) regimen in treatment-experienced HIV-1-infected patients with sustained virological suppression. METHODS:Observational, prospective study. Study population include...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12968
更新日期:2017-08-01 00:00:00
abstract:AIMS:The aim of this study was to assess patient characteristics, medication treatment patterns and healthcare resource utilization among men with existing erectile dysfunction (ED) or benign prostatic hyperplasia (BPH), who are newly diagnosed with the second condition (BPH or ED) compared with those with only one con...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12657
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Overactive bladder (OAB) syndrome has a diverse etiology that disrupts quality of life domains in affected patients. OAB is significantly under-recognised and undertreated, especially in the primary care setting. In order to educate primary care providers about OAB recognition, evaluation and management, we ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13604
更新日期:2020-11-01 00:00:00
abstract::Kaposi's sarcoma (KS) is a recognised complication following kidney transplantation, but the incidence varies according to the geographical area. Although it is a rare tumour, its incidence increases dramatically after solid-organ transplantation. The immunosuppressive medications reactivate human herpes virus 8, whic...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2006.00815.x
更新日期:2006-11-01 00:00:00
abstract::Current and upcoming treatment options for premature ejaculation (PE) are of global clinical interest. In 2008, the International Society for Sexual Medicine published an evidence-based definition for PE. While there are no US Food and Drug Administration-approved therapies for PE, the American Urological Association ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2010.02479.x
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Cutaneous leishmaniasis (CL) is a skin disease characterised by prolonged nodulo-ulcerative lesions of the skin that heals with atrophic scar. Clinical features of CL vary depending on the type of parasite and host immune resistance. The aim of this study was to investigate the clinical features of atypical a...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13730
更新日期:2020-10-26 00:00:00
abstract:OBJECTIVE:Few published studies have examined survival rates for patients with metastatic colorectal cancer (mCRC) by number of lines of treatment received or stage at diagnosis. This study aims to evaluate survival and numbers of lines of treatment in USA mCRC managed care patients. METHODS:To evaluate the impact of ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12543
更新日期:2015-02-01 00:00:00
abstract::Despite huge advances in terms of the impact of antiretroviral therapy on HIV-related morbidity and mortality patients continue to fail therapy. We discuss the reasons why failure occurs including primary or transmitted resistance, poor adherence, toxicity and drug potency. We performed a review of PubMed, Medline and...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2007.01383.x
更新日期:2007-06-01 00:00:00
abstract::The wide variation in the way coronary artery disease (CAD) affects different ethnic groups and the associated risk factor profiles of these groups have been extensively studied, but ethnic differences in the clinical manifestations of peripheral vascular disease (PVD) have been relatively neglected. The aim of the pr...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2002-10-01 00:00:00
abstract:INTRODUCTION:Computed tomography (CT) can be effective for the early screening and diagnosis of COVID-19. This study aimed to investigate the distinctive CT characteristics of two stages of the disease (progression and remission). METHODS:We included all COVID-19 patients admitted to Wenzhou Central Hospital from Janu...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13760
更新日期:2020-10-17 00:00:00
abstract::A randomised, double-blind, parallel, placebo-controlled, 12-week study was carried out to evaluate the efficacy and safety of 20-mg tadalafil taken 'as needed' in a population of men with erectile dysfunction (ED) from Egypt and Turkey. One hundred and thirty-two patients were randomised in this study. Tadalafil was ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2006.00993.x
更新日期:2006-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::A retrospective audit of (99m)Tc-HMPAO SPECT scans was undertaken to assess the utility of brain perfusion imaging in a cohort of young cognitively impaired patients in whom diagnostic uncertainty remained after standard clinical and neuropsychological assessment and structural brain imaging. SPECT scans were assessed...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1368-5031.2005.00499.x
更新日期:2005-04-01 00:00:00
abstract:AIM:Real-world data on treatment patterns/outcomes in patients with advanced melanoma, while scarce, are useful for health technology assessments that govern patient access in many countries. We collected retrospective data on treatment patterns among patients in France, Germany and the UK with Stage IIIB/IIIC melanoma...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12946
更新日期:2017-05-01 00:00:00
abstract::Tuberculosis is an uncommon cause of carpal tunnel syndrome. We report a patient with systemic lupus erythematosus who developed hand numbness. Ultrasonic, operative and microbiological findings supported the diagnosis of median nerve compression secondary to a tuberculous abscess. The symptoms resolved with surgical ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract::Haematogenous metastases to the small bowel are a rare occurrence, usually from malignant melanoma or bronchogenic carcinoma. There are occasional reports of other primary tumours presenting with small bowel involvement as the first evidence of metastases. We describe a case of intraluminal jejunal metastasis from a r...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::This double-blind, randomised placebo-controlled, multicentre study evaluated the efficacy, tolerability and safety of 12 weeks' treatment with controlled release darifenacin 15 mg once daily (qd), in 445 patients with overactive bladder (OAB). The primary endpoint was warning time (time from first sensation of urgenc...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1368-5031.2005.00770.x
更新日期:2006-01-01 00:00:00
abstract:AIMS:The aims of this study were to determine the diagnostic yield of a dedicated heart failure diagnosis clinic and the impact of using different guideline recommended N-terminal pro B-type natriuretic peptide (NT-proBNP) referral thresholds on diagnosis and referral patterns. METHODS AND RESULTS:Patients referred by...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12694
更新日期:2015-11-01 00:00:00
abstract::This randomised, crossover study compared the efficacy, safety, acceptability and patient preference of two multidose powder inhalers (MDPIs)--beclomethasone dipropionate Easyhaler (BDP-EH) and budesonide Turbohaler (BUD-TH)--in 79 stable asthmatics who used inhaled steroids but had no experience of MDPIs. After eight...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2000-07-01 00:00:00
abstract::A 62-year-old man presented with a five-day history of a 'flu-like' illness, epigastric pain and a state of increasing confusion. His serum values for amylase and glucose were grossly elevated, as was the creatine kinase (CK) activity, being 23 times above the upper limit of normal. CK-MB was less than 5% of his total...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract:AIMS:Investigate if angiotensin II receptor blocker (ARB) decreases risk of upper gastrointestinal bleeding (UGIB) in hypertensive patients with chronic kidney disease (CKD) not on dialysis. METHODS:All hypertensive patients with CKD not on dialysis in outpatient department of China Medical University Hospital from 20...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12589
更新日期:2015-07-01 00:00:00