Angiotensin II receptor blocker prevents upper gastrointestinal bleeding in hypertensive patients with chronic kidney disease not on dialysis.

abstract：PURPOSE:Whilst core curricula in neurology are nationally standardised, in real-world clinical practice, different approaches may be taken by individual consultants. The aims of this study were to investigate differences by assessing: (a) variance in diagnostic and investigative practice, using a case-based analysis of...

journal_title：International journal of clinical practice

authors： Aitchison C,Blackburn DJ,Khan A,Grünewald RA,Jenkins TM

更新日期：2020-11-12 00:00:00

abstract：:Overactivity of the renin-angiotensin-aldosterone system (RAAS) plays a key role in the pathophysiology of heart failure (HF) and chronic kidney disease (CKD). RAAS antagonists can significantly improve clinical outcomes, but monotherapy blocks but one step of the RAAS and can be bypassed through compensatory mechanis...

journal_title：International journal of clinical practice

authors： Ziff OJ,Covic A,Goldsmith D

更新日期：2016-07-01 00:00:00

abstract：:It is being questioned if Helicobacter pylori infection, which causes a chronic inflammatory response, can increase the frequency and severity of attacks in patients with Familial Mediterranean Fever (FMF) and if the impact of inflammatory response can be diminished by eradication of the infection. To evaluate if ther...

journal_title：International journal of clinical practice

authors： Ozel AM,Demirturk L,Aydogdu A,Gultepe M,Yazgan Y,Imirzalioglu N,Gurbuz AK,Narin Y

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promising results in the treatment of type 2 diabetes. Herein, we compared the efficacy and safety of once-weekly GLP-1RAs with exenatide and liraglutide separately. METHODS:We systematically surveyed the pertinent literature using ...

journal_title：International journal of clinical practice

authors： Xue X,Ren Z,Zhang A,Yang Q,Zhang W,Liu F

更新日期：2016-08-01 00:00:00

abstract：:The aim was to evaluate 24 hr urine catecholamine, HMMA and HVA excretion in relation to ploidy in phaeochromocytoma. Data from five diploid and nine tetraploid tumours showed a significant reduction in urine noradrenaline (p = 0.02) and HMMA (p = 0.03) in diploid tumours but no difference in adrenaline, dopamine and ...

journal_title：International journal of clinical practice

authors： Tormey WP,Fitzgerald RJ,Thomas G,Kay EW,Leader MB

更新日期：2000-10-01 00:00:00

abstract：:A 60-year-old man noticed rapid enlargement of a long-standing thyroid goitre, with dysphagia and difficulty in breathing. Thyrotoxicosis was diagnosed. Chest X-ray revealed multiple pulmonary metastases. He underwent near-total thyroidectomy. The histopathology revealed an undifferentiated thyroid carcinoma with some...

journal_title：International journal of clinical practice

authors： Plengvidhya N,Rathanavijitrasilp A,Sangruchi T,Nitiyanant W,Vannasaeng S,Piraphatdist T,Vichayanrat A

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Upper gastrointestinal (UGI) haemorrhage is a frequent cause of hospital admission. Scoring systems have been devised to identify those at risk of adverse outcomes. We evaluated the Glasgow Blatchford score's (GBS) ability to identify the need for clinical and endoscopic intervention in patients with UGI hae...

journal_title：International journal of clinical practice

authors： Srirajaskanthan R,Conn R,Bulwer C,Irving P

更新日期：2010-06-01 00:00:00

abstract：:Cigarette smoking induces a significant oxidant effect related to variety of free radical-related diseases often affecting the upper respiratory tract, unless it is effectively compensated by the antioxidant barriers of the humans. In the present study, the evaluation of the antioxidant compensatory mechanisms, by est...

journal_title：International journal of clinical practice

authors： Charalabopoulos K,Assimakopoulos D,Karkabounas S,Danielidis V,Kiortsis D,Evangelou A

更新日期：2005-01-01 00:00:00

abstract：:This randomised, double-blind, placebo-controlled, parallel-group study compared the efficacy and tolerability of lumiracoxib (a novel COX-2 selective inhibitor) with rofecoxib, celecoxib and placebo in patients with moderate-to-severe post-operative dental pain. Following third molar extraction, patients received sin...

journal_title：International journal of clinical practice

authors： Kellstein D,Ott D,Jayawardene S,Fricke J

更新日期：2004-03-01 00:00:00

abstract：:The efficacy of prophylactic carboxymethylcellulose (CMC) in reducing the time to reach full enteral feeds (FEFs) in neonates <32 weeks' gestation was studied in a clinical trial. When ready for feeds, enrolled neonates were allocated to either CMC (dose: CMC content of 12 mg oral erythromycin ethyl succinate syrup, 6...

journal_title：International journal of clinical practice

authors： Patole SK,Muller R

更新日期：2005-05-01 00:00:00

abstract：:The effects of diltiazem treatment on symptoms of chronic anal fissures and their long-term outcome were investigated. One hundred and twelve patients were supplied with 6-week course of 2% diltiazem cream for twice-daily topical application. The medical notes and extended follow-up by telephone for 112 patients were ...

journal_title：International journal of clinical practice

authors： Nash GF,Kapoor K,Saeb-Parsy K,Kunanadam T,Dawson PM

更新日期：2006-11-01 00:00:00

abstract：:The role of clinician educators (CEs) in institutions and medical centres continues to be vital without any doubt. Although there has been more than a century since Sir William Osler established the role of the CE and the tradition by encouraging bed-side teaching, there is still a lack of consensus on the attributes ...

journal_title：International journal of clinical practice

authors： Alexandraki I,Mooradian AD

更新日期：2011-11-01 00:00:00

abstract：:Digitalis has been an old but reliable drug for 240 years. Concerns regarding its clinical indications and benefits still exist in the absence of a reduction in all-cause mortality. While intravenous digitalis is used without question in cases of atrial fibrillation, it is still controversial in sinus rhythm, despite ...

journal_title：International journal of clinical practice

authors： Abarquez RF Jr

更新日期：2001-03-01 00:00:00

abstract：:Carcinoma erysipelatoides, also known as inflammatory metastatic carcinoma, is a rare form of cutaneous metastasis from a malignancy. The characteristic histopathological finding is metastatic tumour cells inside the dermal lymphatic ducts. It is frequently observed in patients with breast carcinoma as well as adenoca...

journal_title：International journal of clinical practice

authors： Yu KJ,Lee HE,Ho HC,Lee JC,Chang JW,Hong HS,Yang CH

更新日期：2005-09-01 00:00:00

abstract：AIM:To determine the prevalence of computer vision syndrome (CVS) and ergonomic practices among students in the Faculty of Medical Sciences at The University of the West Indies (UWI), Jamaica. METHOD:A cross-sectional study was done with a self-administered questionnaire. RESULTS:Four hundred and nine students partic...

journal_title：International journal of clinical practice

authors： Mowatt L,Gordon C,Santosh ABR,Jones T

更新日期：2018-01-01 00:00:00

abstract：:Despite potential benefits, primary care clinicians may avoid using antimuscarinics in men with overactive bladder (OAB) symptoms because of safety concerns. To review the efficacy and safety of antimuscarinics, alone or in combination with an α-blocker, for the treatment of men with OAB symptoms, we conducted a syste...

journal_title：International journal of clinical practice

authors： Kaplan SA,Roehrborn CG,Abrams P,Chapple CR,Bavendam T,Guan Z

更新日期：2011-04-01 00:00:00

abstract：:In a previous report the effectiveness of intraperitoneal bupivacaine in reducing pain following laparoscopic cholecystectomy was demonstrated. Other methods of pain relief are commonly used but none has been compared following laparoscopic cholecystectomy. In two further studies we have compared the analgesic effect ...

journal_title：International journal of clinical practice

authors： Johnson RC,Hedges AR,Morris R,Stamatakis JD

更新日期：1999-01-01 00:00:00

abstract：AIM:Real-world data on treatment patterns/outcomes in patients with advanced melanoma, while scarce, are useful for health technology assessments that govern patient access in many countries. We collected retrospective data on treatment patterns among patients in France, Germany and the UK with Stage IIIB/IIIC melanoma...

journal_title：International journal of clinical practice

authors： Harries M,Mohr P,Grange F,Ehness R,Benjamin L,Siakpere O,Barth J,Stapelkamp C,Pfersch S,McLeod L,Wolowacz S,Kaye JA,Kontoudis I

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is a heterogenous disease with complex pathogenesis. AIM:In this review, we summarise recent progress in the understanding of SLE pathogenesis and discuss implications for the treatment of SLE patients using standard and experimental medications. CONCLUSIONS:The discovery...

journal_title：International journal of clinical practice

authors： Ermann J,Bermas BL

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Anticoagulant therapy in patients with atrial fibrillation (AF) increases the risk of minor bleeding, which is mostly accepted by patients. We aimed to assess whether continuation of anticoagulation despite minor bleeding is associated with a higher level of knowledge on AF and anticoagulation. METHODS AND ...

journal_title：International journal of clinical practice

authors： Metzgier-Gumiela A,Skonieczny G,Konieczyńska M,Desteghe L,Heidbuchel H,Undas A

更新日期：2020-06-01 00:00:00

abstract：AIMS:Many tachy-brady syndrome (TBS) patients, are implanted a permanent pacemaker (PPM) to allow continuation of anti-arrhythmic drug (AAD) therapy to maintain sinus rhythm. Many of these PPM's are implanted as a preventive measure, in absence of symptomatic bradycardia. Our primary aim was to evaluate pacing use amon...

journal_title：International journal of clinical practice

authors： Amir T,Ilan M,Fishman E,Michowitz Y,Khalameizer V,Katz A,Glikson M,Medina A,Rav Acha M

更新日期：2020-10-01 00:00:00

abstract：:It is becoming increasingly common to offer primary percutaneous coronary intervention as first line treatment for ST elevation myocardial infarction (STEMI). In a subset of patients presenting with suspected STEMI, coronary arteries appear normal at coronary angiography. In this article, the current literature of thi...

journal_title：International journal of clinical practice

authors： Meryon I,Patel N,Millane T,Varma C

更新日期：2010-08-01 00:00:00

abstract：AIMS:We aimed to assess the prevalence, components and evolution of polypharmacy and to evaluate risk factors associated with polypharmacy. METHODS:A retrospective dynamic cohort study was performed, using a primary healthcare database comprising Flemish community-dwelling adults aged ≥40 years between 2011 and 2015. ...

journal_title：International journal of clinical practice

authors： Hellemans L,Nuyts S,Hias J,van den Akker M,Van Pottelbergh G,Rygaert X,Spriet I,Vaes B,Tournoy J,Van der Linden L

更新日期：2020-12-19 00:00:00

abstract：INTRODUCTION:Niacin is underutilised because of flushing. Lack of a quantitative tool to assess niacin-induced flushing has precluded the objective evaluation of flushing associated with extended-release (ER) niacin formulations. We developed the Flushing Symptom Questionnaire((c)) (FSQ), a quantitative tool to assess ...

journal_title：International journal of clinical practice

authors： Paolini JF,Mitchel YB,Reyes R,Thompson-Bell S,Yu Q,Lai E,Watson DJ,Norquist JM,Sisk CM,Bays HE

更新日期：2008-06-01 00:00:00

abstract：:This study was aimed to investigate the relationship between plasma fibrinogen level and risk for cognitive decline and dementia in patients with mild cognitive impairment (MCI). Elderly patients with suspected cognitive impairment were screened and evaluated periodically. One hundred and eighty-five patients who met ...

journal_title：International journal of clinical practice

authors： Xu G,Zhang H,Zhang S,Fan X,Liu X

更新日期：2008-07-01 00:00:00

abstract：:Hypercalcemia can be an uncommon manifestation of various infections and malignancies in HIV-positive patients. A case of severe symptomatic hypercalcemia as the first sign of non-Hodgkin's lymphoma in a patient found later to be HIV positive is presented. Differential diagnosis of calcium disorders should include tes...

journal_title：International journal of clinical practice

authors： Lydakis C,Karalis I,Anifantakis K,Tzortzakakis E,Apostolakis T

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of healthcare provider (HCP) type (primary vs. specialist) on glycaemic control and other treatment parameters. RESEARCH DESIGN AND METHODS:Study of Once-Daily Levemir (SOLVE(™) ) is an international, 24-week, observational study of insulin initiation in people with type 2 diabetes....

journal_title：International journal of clinical practice

authors： Orozco-Beltran D,Pan C,Svendsen AL,Faerch L,Caputo S,SOLVE Study Group.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Asthma diagnosis is based on the presence of symptoms and the demonstration of airflow variability. Airway inflammation measured by fractional exhaled nitric oxide, measured at a flow rate of 50 ml/s (FE(NO50)) remains a controversial diagnostic tool. AIM:To assess the ability of FE(NO50) to identify bronch...

journal_title：International journal of clinical practice

authors： Schleich FN,Asandei R,Manise M,Sele J,Seidel L,Louis R

更新日期：2012-02-01 00:00:00

abstract：:With increasing personal access to the internet, and the mass of medical information available in cyberspace, many patients may access information before an outpatient consultation. Since this information may shape individual health beliefs and expectations, yet is acknowledged to be of very variable quality, it may b...

journal_title：International journal of clinical practice

authors： Larner AJ

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:This study aimed to determine the prevalence of gout in a general Turkish population, according to the American College of Rheumatology (Wallace) criteria proposed for gout classification. METHODS:This study was conducted in two districts of Izmir Province in Turkey, and involved 2835 subjects of ≥ 20 years...

journal_title：International journal of clinical practice

authors： Birlik M,Gurler O,Akar S,Sari I,Onen F,Akkoc N

更新日期：2014-06-01 00:00:00