Polypharmacy and excessive polypharmacy in community-dwelling middle aged and aged adults between 2011 and 2015.

abstract：:To evaluate the results of post-operative chemoirradiation for gastric carcinoma. The records of 58 patients who underwent resection for gastric carcinoma were retrospectively reviewed. Forty-six patients had complete resection without any residual disease but with high-risk factors of relapse. Twelve patients had mic...

journal_title：International journal of clinical practice

authors： Bora H,Unsal D,Akmansu M

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Over the last two decades the interest on patent foramen ovale (PFO) as a cause of cardioembolism in cryptogenic stroke has tremendously increased, thanks to the availability of better techniques to diagnose cardiac right-to-left shunt by ultrasounds and of percutaneous means of PFO treatment with interventi...

journal_title：International journal of clinical practice

authors： Savino K,Maiello M,Pelliccia F,Ambrosio G,Palmiero P

更新日期：2016-08-01 00:00:00

abstract：:Proton pump inhibitors are highly effective acid suppressants with decades of use highlighting positive outcomes in millions of patients worldwide, and they offer minimal risk of adverse events. PPIs are considered overutilised when prescribed without an appropriate indication, when patients are left on them 'indefini...

journal_title：International journal of clinical practice

authors： Heidelbaugh JJ,Metz DC,Yang YX

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to compare the performance indicators of risk-adjustment models based on administrative and clinical data in Korea, and to assess whether administrative data alone is useful for comparing quality of care. METHODS:Outcome was defined as death within 30 days of discharge. For ...

journal_title：International journal of clinical practice

authors： Park HK,Yoon SJ,Ahn HS,Ahn LS,Seo HJ,Lee SI,Lee KS

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Guidelines for injury care are increasingly moving away from surgical management towards less invasive procedures but there is a knowledge gap on how these recommendations are influencing practice. We aimed to assess inter-hospital variation in surgical intensity for injury admissions and evaluate the correl...

journal_title：International journal of clinical practice

authors： Patton MP,Moore L,Farhat I,Tardif PA,Gonthier C,Belcaid A,Lauzier F,Turgeon A,Clément J

更新日期：2020-11-01 00:00:00

abstract：:Tissue inflammation has been linked to cancer in several disease models. We tested the association between chronic inflammation and prostate cancer (PCa), as well as high-grade prostatic intraepithelial neoplasia (HGPIN), in prostatic needle biopsy specimens. Tissues from 4526 men, who underwent systematic ultrasound-...

journal_title：International journal of clinical practice

authors： Karakiewicz PI,Benayoun S,Bégin LR,Duclos A,Valiquette L,McCormack M,Bénard F,Saad F,Perrotte P

更新日期：2007-03-01 00:00:00

abstract：:Sulphonylureas (SUs) and biguanides (metformin) are the current mainstays in the treatment of type 2 diabetes (T2DM) and represent the most commonly used oral hypoglycaemic agents (OHAs). In recent years, a variety of new OHAs have become available, including thiazolidinediones, glinides, alpha-glucosidase inhibitors,...

journal_title：International journal of clinical practice

authors： Philippe J,Raccah D

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to compare the thyroid hormone (TH) profile in male infertile subjects with normal and altered sperm parameters and assess its relationship with spermogram and reproductive hormones. DESIGN:This cross-sectional study was conducted in Karachi from August 2017 till September 2018 o...

journal_title：International journal of clinical practice

authors： Rehman R,Zafar A,Fatima SS,Mohib A,Sheikh A

更新日期：2020-09-01 00:00:00

abstract：:In recent years the complexities and heterogeneity of polycystic ovarian syndrome (PCOS) have been recognised. Most PCOS sufferers with amenorrhoea, menstrual dysfunction, hirsutism, acne and infertility can be evaluated and safely managed in primary care. It is prudent to remember that all women with PCOS are at risk...

journal_title：International journal of clinical practice

authors： Gupta S

更新日期：1999-07-01 00:00:00

abstract：:Fracture of the penis can be managed conservatively or surgically. Conservative management is associated with a high morbidity, and early surgical repair of the fracture is usually recommended in order to prevent complications. Because a fractured penis is swollen throughout its length, it is difficult to identify the...

journal_title：International journal of clinical practice

authors： Naraynsingh V,Ramdass MJ,Thomas D,Maharaj D

更新日期：2003-06-01 00:00:00

abstract：:Better understanding of the immunopathogenesis of rheumatoid arthritis over the past few decades has promoted the innovation of new therapeutic approaches targeting the disease more specifically. In addition, refinements in the non-steroidal anti-inflammatory drugs (NSAID) may offer advantages for patients with RA. Th...

journal_title：International journal of clinical practice

authors： Abdelaty EM,Schumacher HR Jr

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:The impact of robot-assisted techniques versus conventional freehand techniques in terms of the accuracy of pedicle screw placement remains conflicting. This meta-analysis was performed to evaluate this relationship. METHODS:A systematic literature search up to July 2020 was performed and 15 studies were de...

journal_title：International journal of clinical practice

authors： Fu W,Tong J,Liu G,Zheng Y,Wang S,Abdelrahim MEA,Gong S

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND:Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, followin...

journal_title：International journal of clinical practice

authors： Jun L,Yuguo C,Zhiguo W,Jinfeng L,Huawei M,Xiuhua L,Yonggui Z,Yanhua X,Kong Y,Hongtao L,Yuliang Z

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:We aimed to compare the efficacy of silodosin and a terpene combination in the treatment of distal ureteral stones. METHODOLOGY:The data of the patients admitted to the urology policlinic with renal colic, diagnosed with distal ureteral stones, and followed up with medical expulsive therapy between December ...

journal_title：International journal of clinical practice

authors： Sahin MO,Sen V,Ongun S,Irer B,Yildiz G

更新日期：2020-11-24 00:00:00

abstract：:Erectile dysfunction (ED) shares the same risk factors as coronary artery disease, so the level of occult cardiovascular risk in men with ED was assessed. A total of 174 men presenting with ED underwent cardiac risk stratification according to the Princeton Consensus Guidelines. Thirty per cent were stratified as inte...

journal_title：International journal of clinical practice

authors： Solomon H,Man J,Wierzbicki AS,O'Brien T,Jackson G

更新日期：2003-03-01 00:00:00

abstract：:This case report describes a patient who presented with pyrexia of unknown origin allied with hypertriglyceridaemia (16.2 mmol/l) but not hypercholesterolaemia (4.1 mmol/l). Investigations identified the cause of the pyrexia as an adult T-cell lymphoma of natural killer cell phenotype (CD3[+], CD7[+], anti-TCR alpha/b...

journal_title：International journal of clinical practice

authors： Suryanarayanan S,Wierzbicki AS,Carr R,Ritter JM

更新日期：2003-12-01 00:00:00

abstract：:The management approach to non-insulin-dependent diabetes mellitus among family doctors in Hong Kong was studied using two case histories. In 1996, all 804 fellows, members and associate members of the Hong Kong College of Family Physicians were sent a letter and a questionnaire. Of the 512 who responded, 405 were mal...

journal_title：International journal of clinical practice

authors： Lam TP,Chan TY

更新日期：1999-03-01 00:00:00

abstract：AIMS:The impact of ongoing PCR positivity on COVID-19 patients and the strategy and period of isolation were not fully understood. We aimed to investigate the factors that cause prolonged PCR positivity and its clinical impact on COVID-19 infection. In addition, we searched for an answer on what length of time would be...

journal_title：International journal of clinical practice

authors： Eser F,Kayaaslan B,Güner R,Hasanoğlu I,Kaya Kalem A,Aypak A,Akinci E

更新日期：2021-01-15 00:00:00

abstract：:High plasminogen activator inhibitor-1 (PAI-1) levels are potential risk factors for cardiovascular disease. The risk profile of white coat hypertension (WCHT) has not yet been completely clear. In this study, we aimed to determine the plasma levels of PAI-1, markers of fibrinolysis and increased cardiovascular diseas...

journal_title：International journal of clinical practice

authors： Coban E,Ozdogan M

更新日期：2004-06-01 00:00:00

abstract：:Riedel's thyroiditis (RT) is an extremely rare form of chronic thyroiditis, characterised by a fibroinflammatory process which partially destroys the thyroid, often involving surrounding tissues. We describe an unusual case of RT in a 38-year-old woman, and discuss its typical clinical, pathological, ultrasound, radio...

journal_title：International journal of clinical practice

authors： Papi G,Corrado S,Cesinaro AM,Novelli L,Smerieri A,Carapezzi C

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Ageing is intrinsically associated with a progressive decline in cardiorespiratory fitness (CRF) as measured by peak oxygen uptake (VO2peak ). Improving CRF through physical activity contribute to better and healthy ageing. High-intensity interval training (HIIT) is a potent method of improving CRF among sen...

journal_title：International journal of clinical practice

authors： Bouaziz W,Malgoyre A,Schmitt E,Lang PO,Vogel T,Kanagaratnam L

更新日期：2020-06-01 00:00:00

abstract：:People in a first episode of psychosis are receiving increasing attention. This study describes the demographic and clinical diagnostic features of a cohort of 84 cases of first episode psychosis presenting in North Derbyshire from October 1999 to October 2000. Forty-two cases falling within the schizophrenia spectrum...

journal_title：International journal of clinical practice

authors： Rowlands RP

更新日期：2001-12-01 00:00:00

abstract：:We present one of the rarer causes of pregnancy-associated jaundice in the immediate puerperium. A 30-year-old multipara with pyruvate kinase deficiency became jaundiced within a few hours of delivery, following an uneventful pregnancy and labour at term. She responded to conservative management, the jaundice clearing...

journal_title：International journal of clinical practice

authors： Esen UI,Olajide F

更新日期：1998-07-01 00:00:00

abstract：AIM:To determine relative prevalence in the same population of urinary incontinence (UI), faecal incontinence (FI) and nocturnal enuresis (NE). To explore attitudes and behaviours relating to help-seeking and beliefs about incontinence prevalence, impact, causes and treatments. DESIGN:Online survey. SUBJECTS:A total ...

journal_title：International journal of clinical practice

authors： Buckley BS,Lapitan MC

更新日期：2009-04-01 00:00:00

abstract：:Day-case and short-stay thyroid surgery is carried out routinely around the world. In the UK longer postoperative stay is usually advocated to circumvent/identify potentially catastrophic complications following thyroidectomy. In the current climate of the National Health Service with focus on patient-centred service,...

journal_title：International journal of clinical practice

authors： Mirnezami R,Sahai A,Symes A,Jeddy T

更新日期：2007-07-01 00:00:00

abstract：:Paliperidone, the 9-hydroxy metabolite of risperidone, was approved on 20 December, 2006 by the US Food and Drug Administration for the treatment of schizophrenia. It is also being tested for the treatment of bipolar mania. An on-line query of http://www.pubmed.gov and http://www.clinicaltrials.gov for 'paliperidone' ...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2007-04-01 00:00:00

abstract：:Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and humans. The reduced form of ZEN, α-ZEA...

journal_title：International journal of clinical practice

authors： Pazaiti A,Kontos M,Fentiman IS

更新日期：2012-01-01 00:00:00

abstract：:Cardiovascular diseases are the principal causes of mortality in middle-aged people and in older people. Coronary heart disease (CHD) is the most common of the cardiovascular diseases; high serum levels of cholesterol are associated with atherosclerosis and an increased risk of CHD. Cholesterol homeostasis is achieved...

journal_title：International journal of clinical practice

authors： Gylling H

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of linagliptin in initial combination with metformin in patients with type 2 diabetes. METHODS:This 1-year randomised, double-blind study was an extension of a 6-month randomised controlled trial, in which adults with type 2 diabetes received one of six treatment regimens...

journal_title：International journal of clinical practice

authors： Haak T,Meinicke T,Jones R,Weber S,von Eynatten M,Woerle HJ

更新日期：2013-12-01 00:00:00

abstract：:People with genuine anxiety disorders can be misdiagnosed and mismanaged, because of negative public and professional attitudes to anxiety and the 'worried well'. Misdiagnosis includes not taking symptoms seriously and giving patients pejorative labels such as 'personality disorder' or 'inadequate'. This can lead to m...

journal_title：International journal of clinical practice

authors： Davies MR

更新日期：2000-01-01 00:00:00