New therapeutic approaches for rheumatoid arthritis.

abstract：BACKGROUND:Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are an established treatment for patients with type 2 diabetes (T2D). Differences between GLP-1RAs in pharmacokinetics, dosing regimens and clinical effects, including cardiovascular (CV) outcomes, mean there may be benefits to switching from one to anothe...

journal_title：International journal of clinical practice

authors： Jain AB,Ali A,Gorgojo Martínez JJ,Hramiak I,Kavia K,Madsbad S,Potier L,Prohaska BD,Strong JL,Vilsbøll T

更新日期：2021-02-01 00:00:00

abstract：:A case of alexia without agraphia is presented. It is a rare but classic disconnection syndrome, first described by Dejerine in 1892. Recent advances in modern neuroimaging techniques such as FLAIR MRI can now localise in vivo the site of origin of the syndrome, especially when computerised axial tomogram of the brain...

journal_title：International journal of clinical practice

authors： Imtiaz KE,Nirodi G,Khaleeli AA

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To assess secondary prevention of fragility fractures by orthopaedic surgeons in the UK and study the effect of multidisciplinary approach in providing secondary prevention. METHODS:A survey was conducted consisting of a postal questionnaire sent to 1000 UK orthopaedic surgeons. 750 valid responses were rece...

journal_title：International journal of clinical practice

authors： Chakravarthy J,Ali A,Iyengar S,Porter K

更新日期：2008-03-01 00:00:00

abstract：AIMS OF THE STUDY:Patient comprehension is a critical part of meeting medical ethics standards of informed consent in study designs. The aim of the study was to determine if sufficient literature exists to require clinicians to disclose the specific risk that COVID-19 vaccines could worsen disease upon exposure to chal...

journal_title：International journal of clinical practice

authors： Cardozo T,Veazey R

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:The association between testosterone deficiency and insulin resistance in men with type 2 diabetes is well established. Current Endocrine Society and European Association of Urology guidelines recommend the measurement of testosterone levels in all men with type 2 diabetes and in men suffering from erectile ...

journal_title：International journal of clinical practice

authors： Hackett G,Cole N,Bhartia M,Kennedy D,Raju J,Wilkinson P,Saghir A,Blast Study Group.

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Patients with chronic obstructive pulmonary disease (COPD) have impaired balance and hence fall more frequently. Easy application of balance evaluation tests can prevent the loss of time in the outpatient clinic for patients with COPD. In this study, we aimed to compare the efficacy of Berg Balance Scale (...

journal_title：International journal of clinical practice

authors： Yazici O,Ceylan E,Demir Yazici S,Tas Gulen S

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:The regular use of simple analgesics in addition to opioids such as paracetamol (or acetaminophen) is recommended for persistent pain to enhance analgesia. Few studies have examined the frequency and doses of paracetamol among people with chronic non-cancer pain including use above the recommended maximum da...

journal_title：International journal of clinical practice

authors： Hoban B,Larance B,Gisev N,Nielsen S,Cohen M,Bruno R,Shand F,Lintzeris N,Hall W,Farrell M,Degenhardt L

更新日期：2015-11-01 00:00:00

abstract：:A comparison was made between the accuracy of Ames and Boehringer reagent strips for detecting urinary tract infections in 100 elderly patients (50 acutely ill patients admitted to hospital and 50 attending the day hospital). The results for urinary nitrite, blood and protein for both strips were documented. Nitrite p...

journal_title：International journal of clinical practice

authors： Evans PJ,McNabb WR,Lewis RR

更新日期：1997-10-01 00:00:00

abstract：:Snoring is a very common source of complaints from partners and neighbours. Snorers themselves are less likely to be affected, unless they have associated daytime sleepiness caused by the sleep disruption from obstructive sleep apnoea. There is increasingly firm evidence that obstructive sleep apnoea is associated wit...

journal_title：International journal of clinical practice

authors： Jarvis S,Rees PJ

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:We aimed to investigate the effect of a low-protein intake on all-cause mortality in subjects with an estimated glomerular filtration rate (eGFR) ≧60 mL/min/1.73 m2 with or without albuminuria using data from the National Health and Nutrition Examination Survey (NHANES). METHODS:We analysed participants in ...

journal_title：International journal of clinical practice

authors： Lee CL,Liu WJ,Wang JS

更新日期：2020-07-01 00:00:00

abstract：:People in a first episode of psychosis are receiving increasing attention. This study describes the demographic and clinical diagnostic features of a cohort of 84 cases of first episode psychosis presenting in North Derbyshire from October 1999 to October 2000. Forty-two cases falling within the schizophrenia spectrum...

journal_title：International journal of clinical practice

authors： Rowlands RP

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:There is abundant evidence that patients with rheumatoid arthritis (RA) are at elevated cardiovascular (CV) risk. The contribution of lipids in general is well recognised, but is as yet unclear in inflammatory diseases such as RA in part because inflammation appears inversely associated with lipid levels in ...

journal_title：International journal of clinical practice

authors： Peters MJ,Voskuyl AE,Sattar N,Dijkmans BA,Smulders YM,Nurmohamed MT

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Although mild asthmatics form the majority of asthma sufferers, there is a relative paucity of evidence-based treatment compared with severe asthmatics. OBJECTIVE:We have performed an up-to-date review of the literature on therapy in this group of patients who form an overlooked but important majority. Pote...

journal_title：International journal of clinical practice

authors： Koh MS,Irving LB

更新日期：2007-08-01 00:00:00

abstract：:Lithium salts have been used in medicine for over a century and are a widely accepted treatment. Clinical practice in the London borough of Barnet led us to suspect that agreed guidelines were not being followed. We checked them against published guidelines and followed up their implementation. A list of patients on l...

journal_title：International journal of clinical practice

authors： Moscovich DG

更新日期：1997-11-01 00:00:00

abstract：AIMS:We aimed to assess the prevalence, components and evolution of polypharmacy and to evaluate risk factors associated with polypharmacy. METHODS:A retrospective dynamic cohort study was performed, using a primary healthcare database comprising Flemish community-dwelling adults aged ≥40 years between 2011 and 2015. ...

journal_title：International journal of clinical practice

authors： Hellemans L,Nuyts S,Hias J,van den Akker M,Van Pottelbergh G,Rygaert X,Spriet I,Vaes B,Tournoy J,Van der Linden L

更新日期：2020-12-19 00:00:00

abstract：:The role of clinician educators (CEs) in institutions and medical centres continues to be vital without any doubt. Although there has been more than a century since Sir William Osler established the role of the CE and the tradition by encouraging bed-side teaching, there is still a lack of consensus on the attributes ...

journal_title：International journal of clinical practice

authors： Alexandraki I,Mooradian AD

更新日期：2011-11-01 00:00:00

abstract：INTRODUCTION:Peripartum cardiomyopathy (PPCM) is an uncommon form of congestive heart failure, afflicting obstetric patients around the time of delivery. The epidemiology of PPCM is infrequently reported. To the best of our knowledge, there has been no report from Asia. OBJECTIVE:To define the prevalence, presentation...

journal_title：International journal of clinical practice

authors： Chee KH,Azman W

更新日期：2009-05-01 00:00:00

abstract：:Acute pulmonary oedema can sometimes complicate adenotonsillectomy carried out for obstructive sleep apnoea. Early recognition and adequate oxygenation are the key to management. We report such a case; the pathophysiology and management of this rare complication of a common procedure are discussed. ...

journal_title：International journal of clinical practice

authors： Motamed M,Djazaeri B,Marks R

更新日期：1999-04-01 00:00:00

abstract：:Current and upcoming treatment options for premature ejaculation (PE) are of global clinical interest. In 2008, the International Society for Sexual Medicine published an evidence-based definition for PE. While there are no US Food and Drug Administration-approved therapies for PE, the American Urological Association ...

journal_title：International journal of clinical practice

authors： Hellstrom WJ

更新日期：2011-01-01 00:00:00

abstract：AIM:Variations of dopamine receptor type 2 (DRD2) are among the key factors involved in the pathology of schizophrenia. Presence of certain SNPs in DRD2 gene also amend patients' response to antipsychotics. Keeping in view the genetic diversity among populations and important role of DRD2 polymorphisms in schizophrenia...

journal_title：International journal of clinical practice

authors： Amir QU,Hanif F,Washdev W,Bilwani F,Usman Simjee S

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:The current review describes how the health status profile of people with fibromyalgia (FM) compares to that of people in the general population and patients with other health conditions. METHODS:A review of 37 studies of FM that measured health status with the 36-item Medical Outcomes Study Short-Form Healt...

journal_title：International journal of clinical practice

authors： Hoffman DL,Dukes EM

更新日期：2008-01-01 00:00:00

abstract：AIMS:To validate a previously developed set of explicit criteria for the appropriateness of hospital admission among these patients using the RAND/UCLA Appropriateness Methodology (RAM). METHODS:We conducted a prospective cohort study of patients experiencing symptoms of COPD exacerbation seen in the emergency departm...

journal_title：International journal of clinical practice

authors： Garcia-Gutierrez S,Quintana JM,Bilbao A,Unzurrunzaga A,Esteban C,Baré M,Girón Moreno RM,Pulido E,Rivas P,IRYSS-COPD Appropriateness Study (IRYSS-COPD) Group.

更新日期：2014-07-01 00:00:00

abstract：AIM:This study aimed to determine the impact of long-term treatment with continuous positive airway pressure (CPAP) and obstruction relieving surgical procedure on obstructive sleep apnoea syndrome (OSAS) patients on erectile function (EF). METHODS:Eighty male OSAS patients, suffering from erectile dysfunction (ED) we...

journal_title：International journal of clinical practice

authors： Khafagy AH,Khafagy AH

更新日期：2012-12-01 00:00:00

abstract：AIMS:To investigate the evolution of the quality of life of patients with chronic obstructive pulmonary disease (COPD) and quantify the impact of exacerbations on the deterioration of quality of life over 2 years. METHODS:Multicentre, observational, prospective 2-year study carried out in primary care. Patients with C...

journal_title：International journal of clinical practice

authors： Llor C,Molina J,Naberan K,Cots JM,Ros F,Miravitlles M,EVOCA study group.

更新日期：2008-04-01 00:00:00

abstract：:To evaluate the results of post-operative chemoirradiation for gastric carcinoma. The records of 58 patients who underwent resection for gastric carcinoma were retrospectively reviewed. Forty-six patients had complete resection without any residual disease but with high-risk factors of relapse. Twelve patients had mic...

journal_title：International journal of clinical practice

authors： Bora H,Unsal D,Akmansu M

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Alternatives to acute hospital admission are required to accommodate the increasing pressures on health services. Since physiotherapists and occupational therapists are integral to inpatient teams, they may also be integral to admission replacement services, and thus their roles in these services merit inves...

journal_title：International journal of clinical practice

authors： Harris C,Ignatowicz A,Lasserson DS

更新日期：2020-06-01 00:00:00

abstract：:The UK National Health Service (NHS) currently spends in excess of £250 million per annum on angiotensin II receptor blockers (ARBs) for the treatment of hypertension and heart failure; with candesartan currently dominating the market. With the recent introduction of generic losartan, we set out to directly compare th...

journal_title：International journal of clinical practice

authors： Grosso AM,Bodalia PN,Macallister RJ,Hingorani AD,Moon JC,Scott MA

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND/AIMS:Simple compound of Helicobacter pylori eradication therapy may improve drug compliance of patients. The aims of this study were to compare the efficacy and tolerability of a simple combination containing levofloxacin 7-day once-daily with standard twice-daily triple therapy. PATIENTS AND METHODS:This w...

journal_title：International journal of clinical practice

authors： Chen LW,Chien RN,Chang JJ,Fang KM,Chang LC

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Chronic pelvic pain (CPP) is a common and complex disease whose cause is often clinically inexplicable, with consequent difficulty in diagnosis and treatment. Patients with CPP have high levels of anxiety and depression, with a consequent impairment of their quality of life. AIMS:The objective of this study...

journal_title：International journal of clinical practice

authors： Romão AP,Gorayeb R,Romão GS,Poli-Neto OB,dos Reis FJ,Rosa-e-Silva JC,Nogueira AA

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:In the setting of an increasing workload for radiologists, this study focuses on the feasibility of skill mixing in breast imaging in a hospital radiology department. METHODS:Two radiological technologists with more than 10 years of experience in performing mammograms were trained in prereading mammograms to s...

journal_title：International journal of clinical practice

authors： van den Biggelaar FJ,Kessels AG,van Engelshoven JM,Flobbe K

更新日期：2010-03-01 00:00:00