Abstract:
BACKGROUND:We aimed to investigate the effect of a low-protein intake on all-cause mortality in subjects with an estimated glomerular filtration rate (eGFR) ≧60 mL/min/1.73 m2 with or without albuminuria using data from the National Health and Nutrition Examination Survey (NHANES). METHODS:We analysed participants in the NHANES from 2003 to 2010. We excluded participants with an eGFR less than 60 mL/min/1.73 m2 from the analyses. Low-protein intake was defined as a protein intake of less than 0.8 g/kg/day. The Healthy Eating Index 2010 was used to assess diet quality. The vital status of all participants in the NHANES was determined by linking to the National Death Index through the end of 2011. The hazard ratios (HRs) for the association of low-protein intake and mortality were determined using weighted Cox proportional hazards regression models. RESULTS:A total of 7730 participants were included in the analyses. After a median follow up of 4.7 years, 462 participants died. A low-protein intake was associated with a higher risk of mortality (HRs 1.394, 95% CI 1.121-1.734, P = .004) with adjustment for diet quality and relevant risk factors. The higher risk of mortality associated with a low-protein intake was consistent in subjects with or without albuminuria (P interaction .280). CONCLUSION:A protein intake of less than 0.8 g/kg/day was associated with a higher risk of mortality in subjects with an eGFR ≧60 mL/min/1.73 m2 , irrespective of whether they had albuminuria.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Lee CL,Liu WJ,Wang JSdoi
10.1111/ijcp.13505subject
Has Abstractpub_date
2020-07-01 00:00:00pages
e13505issue
7eissn
1368-5031issn
1742-1241journal_volume
74pub_type
杂志文章abstract:AIMS OF STUDY:To compare a novel oxidative stress biomarker dynamic thiol/disulphide homoeostasis between patients with lung tuberculosis and healthy controls. METHODS:Our study included 50 patients with active lung tuberculosis and 50 healthy controls. Serum thiol/disulphide was measured with a new automated spectrom...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13998
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:The impact of robot-assisted techniques versus conventional freehand techniques in terms of the accuracy of pedicle screw placement remains conflicting. This meta-analysis was performed to evaluate this relationship. METHODS:A systematic literature search up to July 2020 was performed and 15 studies were de...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.13964
更新日期:2020-12-28 00:00:00
abstract:AIMS:There is evidence suggesting that the respiratory response to sedation is different in patients with sleep apnoea, which is common in patients with chronic renal failure (CRF). This study examined the respiratory response of sedation with propofol and alfentanil, whose pharmacokinetics are not affected by the rena...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01443.x
更新日期:2010-01-01 00:00:00
abstract:AIM:To assess the efficacy and safety of dipeptidyl peptidase 4-inhibitors (DPP4-I) compared with sulphonylureas in adults with type 2 diabetes (T2D) mellitus. METHOD:Randomised controlled trials were collected from PubMed, EMBASE, Google Scholar and conference. The primary outcome was the change in HbA1c. Secondary o...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ijcp.12761
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Stroke risk is heightened among patients who have had a primary stroke or transient ischaemic attack (TIA). The primary care physician is in the best position to monitor these patients for stroke recurrence. Because stroke recurrence can occur shortly after the primary event, guidelines recommend initiating ...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2007.01515.x
更新日期:2007-10-01 00:00:00
abstract:AIMS:To validate a previously developed set of explicit criteria for the appropriateness of hospital admission among these patients using the RAND/UCLA Appropriateness Methodology (RAM). METHODS:We conducted a prospective cohort study of patients experiencing symptoms of COPD exacerbation seen in the emergency departm...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12397
更新日期:2014-07-01 00:00:00
abstract::Coronary heart disease (CHD) is the leading cause of death worldwide, and effective treatment of hyperlipidaemia can prevent development of CHD and significantly reduce the risk for cardiovascular events and mortality in this disease. The advent of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:2001-07-01 00:00:00
abstract::'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2011.02825.x
更新日期:2012-01-01 00:00:00
abstract::It is becoming increasingly common to offer primary percutaneous coronary intervention as first line treatment for ST elevation myocardial infarction (STEMI). In a subset of patients presenting with suspected STEMI, coronary arteries appear normal at coronary angiography. In this article, the current literature of thi...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2010.02394.x
更新日期:2010-08-01 00:00:00
abstract::An increasing number of patients aged>or=70 years are presenting for elective non-cardiac surgery. We undertook this study to: (i) compare the nature and distribution of cardiovascular disease (CVD) risk factors in an at risk population of patients aged>or=70 years undergoing elective surgery compared with a younger a...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01304.x
更新日期:2007-05-01 00:00:00
abstract::Marijuana is the most commonly used illicit drug while its abuse and dependence has an increasing prevalence among the young population. Marijuana smoking affects the circulatory system triggering various cardiovascular events. Of note, recent case reports indicate a possible association with atrial fibrillation (AF)....
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2007.01505.x
更新日期:2008-02-01 00:00:00
abstract:AIMS:This was a post hoc analysis to determine whether baseline severity of depression influenced the efficacy of duloxetine in treating major depressive disorder (MDD) and to better characterise the symptom response profile for duloxetine in patients with mild, moderate or more severe depression. METHODS:Data were po...
journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1742-1241.2007.01444.x
更新日期:2007-08-01 00:00:00
abstract::The Surgical Nutrition Advisory Team (SNAT) of our hospital, formed in October 1992, decided to study the impact of such a team on the six months before and after its formation on catheter care and nutritional support in total parenteral nutrition. Our study showed that with a dedicated nutritional team, catheter seps...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:AIMS:To evaluate in a real-world setting the effectiveness of exenatide once-weekly (ExQW) in patients with T2D and to determine predictors of glycaemic and weight response to this drug at 6 months. METHODS:Observational, retrospective, multicenter study in adult patients with T2D and BMI ≥30 kg/m2 from 4 tertiary Spa...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1111/ijcp.13055
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Studies have demonstrated the beneficial effect of normal and high body mass index (BMI) upon risk of osteoporosis (OP). No study has investigated the prevalence of OP in an older population with a very high BMI (higher than 40 kg/m(2) ). METHODS:Data of patients aged over 50 years that attended for a dual ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12371
更新日期:2014-06-01 00:00:00
abstract:AIMS:To assess the extent of reduction in blood pressure (BP) of aliskiren/amlodipine combination therapy compared with amlodipine monotherapy in moderate-to-severe hypertensive patients. METHODS:This was an 8-week multicentre, randomised, double-blind study. After a 1-to 4-week washout period, eligible patients [mean...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2012.02967.x
更新日期:2012-09-01 00:00:00
abstract::In this review, we discuss right-sided heart valve disease, namely tricuspid regurgitation (TR), tricuspid stenosis, pulmonary regurgitation, pulmonary stenosis and right-sided endocarditis. These are frequently seen in conjunction with other diseases, making assessment of their significance more difficult, but it has...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12485
更新日期:2014-10-01 00:00:00
abstract::Calcium dobesilate (Doxium) is used in the treatment of diabetic retinopathy. Clinical studies show a slowdown of the progression of the disease after long-term oral treatment. The main action of the drug is related to a reduction of microvascular permeability as measured by different parameters and methods (vitreous ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::This study was aimed to investigate the relationship between plasma fibrinogen level and risk for cognitive decline and dementia in patients with mild cognitive impairment (MCI). Elderly patients with suspected cognitive impairment were screened and evaluated periodically. One hundred and eighty-five patients who met ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01268.x
更新日期:2008-07-01 00:00:00
abstract::Both the incidence of twin pregnancy and the demand for prenatal diagnosis are increasing. Unfortunately, biochemical screening and ultrasound scanning are less reliable for prenatal diagnosis in twin pregnancies than in singletons. Amniocentesis and chorionic villous biopsy are usually diagnostic in singleton pregnan...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:To explore the association between illicit drug use (IDU) and cardiometabolic disease risk factors (CDRF) in a nationally representative sample of adults. METHODS:The 2005-2008 National Health and Nutrition Examination Surveys data from 20- to 45-year-old adults (n = 8738) were utilised to analyze the relation...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12189
更新日期:2013-11-01 00:00:00
abstract::Despite differences in design, many large epidemiological studies using well-powered multivariate analyses consistently provide overwhelming evidence of a link between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Preclinical evidence suggests that several common pathophysiological mechanisms are ...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12176
更新日期:2013-07-01 00:00:00
abstract::In recent years the complexities and heterogeneity of polycystic ovarian syndrome (PCOS) have been recognised. Most PCOS sufferers with amenorrhoea, menstrual dysfunction, hirsutism, acne and infertility can be evaluated and safely managed in primary care. It is prudent to remember that all women with PCOS are at risk...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract:INTRODUCTION AND PURPOSE:The need for aggressive efforts to help tobacco users quit remains a healthcare priority. Brief interventions delivered in the healthcare environment continue to be a valuable component of a comprehensive tobacco control policy. Unfortunately, such treatments are offered less often than desired...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.12386
更新日期:2014-07-01 00:00:00
abstract::This randomised, double-blind, placebo-controlled, parallel-group study compared the efficacy and tolerability of lumiracoxib (a novel COX-2 selective inhibitor) with rofecoxib, celecoxib and placebo in patients with moderate-to-severe post-operative dental pain. Following third molar extraction, patients received sin...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1368-5031.2004.00155.x
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Subjects with the metabolic syndrome are accompanied by insulin resistance (IR). However, it is not clear how well the newly defined metabolic syndrome identifies IR specifically in hypertensive subjects. AIMS:The purpose of the study was to evaluate the performance of the metabolic syndrome, defined by the...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2008.01818.x
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Erectile dysfunction (ED) is a common medical condition. In the UK, approximately 2.3 million men suffer from moderate-to-severe ED, many of whom do not consult a healthcare professional about the problem. Phosphodiesterase-type 5 (PDE5) inhibitors have revolutionised treatment for ED and three such drugs ar...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02123.x
更新日期:2009-08-01 00:00:00
abstract:AIM:This study aimed to determine the impact of long-term treatment with continuous positive airway pressure (CPAP) and obstruction relieving surgical procedure on obstructive sleep apnoea syndrome (OSAS) patients on erectile function (EF). METHODS:Eighty male OSAS patients, suffering from erectile dysfunction (ED) we...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2012.02990.x
更新日期:2012-12-01 00:00:00
abstract::For further improvement of coronary heart disease (CHD) management large epidemiological studies are required to characterise the real population of patients with CHD, treated in the primary care settings, and to evaluate how the guidelines are implemented in the everyday clinical practice. The aim of the Angina Treat...
journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1742-1241.2004.00234.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Maternal responsiveness seems to be necessary for a child to develop a safe attachment. However, even after many years of research on maternal responsiveness, only a few attempts have been made to find ways of promoting mother and child interaction. This study aimed at determining the association between mat...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/ijcp.14043
更新日期:2021-01-23 00:00:00