Abstract:
INTRODUCTION:Peripartum cardiomyopathy (PPCM) is an uncommon form of congestive heart failure, afflicting obstetric patients around the time of delivery. The epidemiology of PPCM is infrequently reported. To the best of our knowledge, there has been no report from Asia. OBJECTIVE:To define the prevalence, presentation and outcome of PPCM in a major referral centre in Malaysia. METHODOLOGY:Retrospective case record analysis of all patients admitted and diagnosed with PPCM at the University Malaya Medical Centre, Kuala Lumpur, over 5 years from 1st January, 2001 to 31st December, 2004. RESULTS:Eight patients were diagnosed with PPCM over the study period reflecting a prevalence of 34: 100,000 life births. Five were diagnosed within 5 months after delivery. Three were associated with twin pregnancies. There was one death (12.5% mortality). The mean left ventricular ejection fraction (LVEF) at the time of diagnosis was 27.1 +/- SD 6.4% (range: 17-35%). Following the index event, the left ventricular function recovered in three of the eight patients (37.5%) with restoration of normal LVEF (LVEF > 50%). Two patients had subsequent pregnancies. One was terminated at 7 weeks, and the other delivered uneventfully with a normal LVEF. CONCLUSIONS:Peripartum cardiomyopathy is uncommon in Malaysia. It appears to be associated with twin pregnancy. The outcome is variable with 37.5% recovering normal left ventricular function, 12.5% mortality and persistently impaired left ventricular function in the remainder.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Chee KH,Azman Wdoi
10.1111/j.1742-1241.2007.01449.xsubject
Has Abstractpub_date
2009-05-01 00:00:00pages
722-5issue
5eissn
1368-5031issn
1742-1241pii
IJCP1449journal_volume
63pub_type
杂志文章abstract:OBJECTIVE:To assess secondary prevention of fragility fractures by orthopaedic surgeons in the UK and study the effect of multidisciplinary approach in providing secondary prevention. METHODS:A survey was conducted consisting of a postal questionnaire sent to 1000 UK orthopaedic surgeons. 750 valid responses were rece...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2007.01662.x
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2006-04-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究
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更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2009-02-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
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更新日期:2007-04-01 00:00:00
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