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Proton pump inhibitors: are they overutilised in clinical practice and do they pose significant risk?

Abstract：

:Proton pump inhibitors are highly effective acid suppressants with decades of use highlighting positive outcomes in millions of patients worldwide, and they offer minimal risk of adverse events. PPIs are considered overutilised when prescribed without an appropriate indication, when patients are left on them 'indefinitely' without appropriate indications and when they are continued after being utilised for most cases of hospital SUP. While several adverse outcomes have been linked to PPI therapy, most data are from retrospective observational studies that may be subject to confounding and bias.

journal_name

Int J Clin Pract

journal_title

International journal of clinical practice

authors

Heidelbaugh JJ,Metz DC,Yang YX

doi

10.1111/j.1742-1241.2012.02921.x

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

582-91

issue

6

eissn

1368-5031

issn

1742-1241

journal_volume

66

pub_type

杂志文章,评审

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