Abstract：
:In 2006 Meiron Thomas, writing in the British Journal of Surgery, made the following statement about the value of sentinel lymph node biopsy (SLNB) as a staging procedure in cutaneous malignant melanoma (1): "Perhaps a more important concern for those hoping to gain reassurance from accurate nodal staging relates to positive SN(S) that are prognostically inaccurate, information that can be devastating for the patient, leading to unnecessary lymphadenectomy and possibly unnecessary adjuvant therapy". In September 2011 Meyrick Ross and Gershenwald, writing in the Journal of Surgical Oncology, made the following statement about the management of patients with cutaneous malignant melanoma (2): "Sentinel node biopsy has become an important component of the initial management of many of these patients for accurate staging of regional lymph nodes, as well as enhanced regional disease control and improved survival in the patients with microscopically involved nodes." These two extremes have polarized the debate about the proper management of patients with malignant melanoma and have lead to widespread confusion and dismay amongst practicing clinicians, GP's and patient groups. In fact both statements are inaccurate, misleading and result from a false reading of the literature and in the case of Ross and Gershenwald a false interpretation of their own data (3). The following article explains why.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Russell-Jones Rdoi
10.1111/j.1742-1241.2011.02829.xsubject
Has Abstractpub_date
2012-07-01 00:00:00pages
671-4issue
7eissn
1368-5031issn
1742-1241journal_volume
66pub_type
杂志文章,评审abstract：:Spinal neurenteric cysts are rare congenital cysts of endodermal origin. A 34-year-old man presented with burning feet syndrome lasting two years. Magnetic resonance imaging (MRI) revealed an intradural extramedullary cystic mass extending from L2 to L5 causing severe compression of the terminal portion of the conus m...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:The objectives of this study were to compare the performance indicators of risk-adjustment models based on administrative and clinical data in Korea, and to assess whether administrative data alone is useful for comparing quality of care. METHODS:Outcome was defined as death within 30 days of discharge. For ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1742-1241.2007.01345.x
更新日期：2007-07-01 00:00:00
abstract：:A 60-year-old man noticed rapid enlargement of a long-standing thyroid goitre, with dysphagia and difficulty in breathing. Thyrotoxicosis was diagnosed. Chest X-ray revealed multiple pulmonary metastases. He underwent near-total thyroidectomy. The histopathology revealed an undifferentiated thyroid carcinoma with some...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:There is substantial evidence that many patients with impaired left ventricular function secondary to coronary artery disease may have hibernating or stunned myocardium. The identification of these patients is important, as revascularisation is associated with an improvement in function, and there is some evidence tha...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：AIMS:The aims of this study were to determine the diagnostic yield of a dedicated heart failure diagnosis clinic and the impact of using different guideline recommended N-terminal pro B-type natriuretic peptide (NT-proBNP) referral thresholds on diagnosis and referral patterns. METHODS AND RESULTS:Patients referred by...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12694
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Over the last two decades the interest on patent foramen ovale (PFO) as a cause of cardioembolism in cryptogenic stroke has tremendously increased, thanks to the availability of better techniques to diagnose cardiac right-to-left shunt by ultrasounds and of percutaneous means of PFO treatment with interventi...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/ijcp.12842
更新日期：2016-08-01 00:00:00
abstract：:Over the past years, there has been an explosive increase in the prevalence of type 2 diabetes (T2DM) and this is expected to continue, entailing associated morbidity and mortality. An increasing number of studies explore the different ways T2DM could be prevented. On-going lifestyle modifications need to be addressed...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2006.00929.x
更新日期：2006-05-01 00:00:00
abstract：:Better understanding of the immunopathogenesis of rheumatoid arthritis over the past few decades has promoted the innovation of new therapeutic approaches targeting the disease more specifically. In addition, refinements in the non-steroidal anti-inflammatory drugs (NSAID) may offer advantages for patients with RA. Th...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-01 00:00:00
abstract：:Calcium dobesilate (Doxium) is used in the treatment of diabetic retinopathy. Clinical studies show a slowdown of the progression of the disease after long-term oral treatment. The main action of the drug is related to a reduction of microvascular permeability as measured by different parameters and methods (vitreous ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:Paliperidone, the 9-hydroxy metabolite of risperidone, was approved on 20 December, 2006 by the US Food and Drug Administration for the treatment of schizophrenia. It is also being tested for the treatment of bipolar mania. An on-line query of http://www.pubmed.gov and http://www.clinicaltrials.gov for 'paliperidone' ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01321.x
更新日期：2007-04-01 00:00:00
abstract：:In a five-year retrospective data analysis, incidence of > stage II necrotising enterocolitis (NEC) was four times higher in aboriginal (18/125) than non-aboriginal (11/306) neonates, all < or = 32 weeks' gestation. Stage III NEC occurred more frequently (10/18 vs 3/11) and related mortality was higher (44.4% vs 0%) i...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:Studies in the primary care setting are of high interest for assessing the management situation of patients with manifestations of atherothrombosis. AIMS:Therefore, we documented diagnostic procedures, characteristics, and management of patients with symptomatic and asymptomatic peripheral arterial disease ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2010.02337.x
更新日期：2010-06-01 00:00:00
abstract：:Gastrointestinal tract (GIT) foreign bodies represent a significant clinical problem in the Emergency Department, causing a high degree of financial burden, morbidity and mortality. A large variety of foreign bodies are accidentally ingested or inserted into the GIT in different age groups. This a retrospective review...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2006.00709.x
更新日期：2006-06-01 00:00:00
abstract：BACKGROUND:Budesonide/formoterol is an effective treatment for both asthma and chronic obstructive pulmonary disease. This study compared the efficacy and safety of a novel hydrofluoroalkane (HFA) pressurised metered-dose inhaler (pMDI) formulation of budesonide/formoterol with that of budesonide pMDI and budesonide/fo...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1742-1241.2007.01574.x
更新日期：2007-11-01 00:00:00
abstract：:The aim of this study was to assess the interventions by general practitioners on cardiovascular risk factors among persons without a history of cardiovascular disease attending for a cardiovascular check-up. All inhabitants of three Belgian towns aged between 45 and 64 years were invited for a cardiovascular check-up...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1368-5031.2004.0104.x
更新日期：2004-02-01 00:00:00
abstract：:Both the incidence of twin pregnancy and the demand for prenatal diagnosis are increasing. Unfortunately, biochemical screening and ultrasound scanning are less reliable for prenatal diagnosis in twin pregnancies than in singletons. Amniocentesis and chorionic villous biopsy are usually diagnostic in singleton pregnan...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND:Lozenges containing Amylmetacresol and 2,4-Dichlorobenzylalcohol (AMC/DCBA, eg Strepsils® ) are marketed as a remedy for acute sore throat. This over-the-counter formulation has antiseptic and local anaesthetic qualities. OBJECTIVES:The objective of this systematic review and meta-analysis is to evaluate th...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/ijcp.13002
更新日期：2017-10-01 00:00:00
abstract：:Current therapy in Russia for long-term management of asthma is mainly non-steroidal. This provided the opportunity to compare the efficacy and safety of formoterol (Oxis) Turbuhaler plus budesonide (Pulmicort) Turbuhaler with budesonide Turbuhaler alone in adults (n=338) with mild to moderate asthma who had little pr...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Although data about circadian variation of myocardial infarction (MI) in western populations reveal morning peak between 06:00 and 12:00 hours, differences have been reported in different regions of the world and ethnic groups. We aimed to evaluate circadian variation of MI in a Turkish cohort. METHODS:A to...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2008.01717.x
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Ageing is intrinsically associated with a progressive decline in cardiorespiratory fitness (CRF) as measured by peak oxygen uptake (VO2peak ). Improving CRF through physical activity contribute to better and healthy ageing. High-intensity interval training (HIIT) is a potent method of improving CRF among sen...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析
doi：10.1111/ijcp.13490
更新日期：2020-06-01 00:00:00
abstract：:Nitrates are useful drugs in cardiovascular medicine. They have a presumed vasovagal effect, which is a rare but often under-recognised complication that is partly caused by central inhibition of the sympathetic nervous system. However, no consistent variable associated with the presumed vasovagal effects following ni...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1998-09-01 00:00:00
abstract：:Prescriptions for short-acting beta(2)-agonists (SABAs) and oral corticosteroids recorded in a primary care database were used as markers of asthma control. Drug use in the 6 months before and after step-up in treatment from inhaled corticosteroids [ICs; total daily dosage of < or =1000 microg beclomethasone dipropion...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2005.00455.x
更新日期：2005-02-01 00:00:00
abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with gastrointestinal adverse effects, ranging from dyspepsia and peptic ulcer disease to more serious complications such as haemorrhage or perforation. NSAID-induced gastrointestinal toxicity is a significant medical problem worldwide. Misoprostol is effec...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2005.00660.x
更新日期：2005-10-01 00:00:00
abstract：:Tumour markers are used for diagnosis, staging, evaluation of response to treatment, prognosis and detection of recurrences in clinical oncology. In this study, we aim to investigate the levels of insulin-like growth factor (IGF)-I and IGF-binding protein (IGFBP)-III in cases with oesophageal carcinoma. We investigate...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2006.00854.x
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Urinary tract infections (UTI) and asymptomatic bacteriuria (AB) during pregnancy can result in considerable maternal and foetal adverse outcomes. Production of extended-spectrum beta-lactamase (ESBL) is a major antibiotic resistance mechanism by Enterobacteriaceae. OBJECTIVES:To determine the global preval...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13422
更新日期：2019-09-18 00:00:00
abstract：:It is difficult to make a diagnosis when malignancy presents as fever of unknown origin (FUO). In order to update information on this disease entity, we performed a retrospective survey on adult cancer patients (n=48) presenting with FUO who were admitted to our university hospital between 1989 and 2002. All 48 patien...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:'Clinimetrics' is the term introduced by Alvan R. Feinstein in the early 1980s to indicate a domain concerned with indexes, rating scales and other expressions that are used to describe or measure symptoms, physical signs and other clinical phenomena. Clinimetrics has a set of rules that govern the structure of indexe...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2011.02825.x
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:Patients with atrial fibrillation (AF) are more symptomatic than patients with sinus rhythm. However, it is unknown what per cent of time spent in AF is associated with symptoms. METHODS:We used a limited access dataset from the Atrial Fibrillation Follow-up Investigation of Rhythm Management trial. Patie...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12262
更新日期：2014-04-01 00:00:00
abstract：AIMS:This was a post hoc analysis to determine whether baseline severity of depression influenced the efficacy of duloxetine in treating major depressive disorder (MDD) and to better characterise the symptom response profile for duloxetine in patients with mild, moderate or more severe depression. METHODS:Data were po...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1742-1241.2007.01444.x
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:People with depressive disorders or subsyndromal symptoms of depression (SSD) often use complementary and alternative therapies, including massage therapy (MT). This systematic review evaluates the evidence, from randomised clinical trials (RCTs), for the effectiveness of multiple sessions of classical Europ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01553.x
更新日期：2008-02-01 00:00:00
