Short-acting beta 2-agonist and oral corticosteroid use in asthma patients prescribed either concurrent beclomethasone and long-acting beta 2-agonist or salmeterol/fluticasone propionate combination.

abstract：:Aortic valve disease is common and has significant impact on prognosis and quality of life. In this educational review, we cover the pathophysiology, presentation and assessment of aortic stenosis (AS) and aortic regurgitation (AR), including the role of imaging modalities beyond echocardiography. We review current tr...

journal_title：International journal of clinical practice

authors： Rayner J,Coffey S,Newton J,Prendergast BD

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Stroke risk is heightened among patients who have had a primary stroke or transient ischaemic attack (TIA). The primary care physician is in the best position to monitor these patients for stroke recurrence. Because stroke recurrence can occur shortly after the primary event, guidelines recommend initiating ...

journal_title：International journal of clinical practice

authors： Kirshner HS

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown promising results in the treatment of type 2 diabetes. Herein, we compared the efficacy and safety of once-weekly GLP-1RAs with exenatide and liraglutide separately. METHODS:We systematically surveyed the pertinent literature using ...

journal_title：International journal of clinical practice

authors： Xue X,Ren Z,Zhang A,Yang Q,Zhang W,Liu F

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Cardiovascular medications are effective in prevention of cardiovascular diseases (CVD); however, medication non-adherence contributes to morbidity and mortality. OBJECTIVE:This systematic review and meta-analysis aims to summarise the evidence regarding the relationship between characteristics of drug th...

journal_title：International journal of clinical practice

authors： Schneider APH,Gaedke MÂ,Garcez A,Barcellos NT,Paniz VMV

更新日期：2018-01-01 00:00:00

abstract：AIMS:Fabry disease (FD) is an X-linked inborn error of metabolism caused by alpha-galactosidase A deficiency. The Fabry Registry is an ongoing, global observational database that compiles clinical data from patients with FD. METHODS:Demographic and baseline clinical characteristics of Fabry Registry patients enrolled ...

journal_title：International journal of clinical practice

authors： Politei JM,Cabrera G,Amartino H,Valdez R,Masllorens F,Ripeau D,Antongiovanni N,Soliani A,Luna P,Cedrolla M,Fernandez S,Fainboim A

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The influence of cardiovascular risk factors/comorbidities on response to oral once-daily tadalafil 5 mg was explored in men with lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH). METHODS:This post hoc analysis pooled data from four double-blind studies in which 1498 men wit...

journal_title：International journal of clinical practice

authors： Vlachopoulos C,Oelke M,Maggi M,Mulhall JP,Rosenberg MT,Brock GB,Esler A,Büttner H

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Studies in the primary care setting are of high interest for assessing the management situation of patients with manifestations of atherothrombosis. AIMS:Therefore, we documented diagnostic procedures, characteristics, and management of patients with symptomatic and asymptomatic peripheral arterial disease ...

journal_title：International journal of clinical practice

authors： Kröger K,Schwertfeger M,Pittrow D,Diehm C

更新日期：2010-06-01 00:00:00

abstract：:The UK National Health Service (NHS) currently spends in excess of £250 million per annum on angiotensin II receptor blockers (ARBs) for the treatment of hypertension and heart failure; with candesartan currently dominating the market. With the recent introduction of generic losartan, we set out to directly compare th...

journal_title：International journal of clinical practice

authors： Grosso AM,Bodalia PN,Macallister RJ,Hingorani AD,Moon JC,Scott MA

更新日期：2011-03-01 00:00:00

abstract：AIMS:This study examines women's experience of healthcare following the referral for hysterosalpingography (HSG) after a period of subfertility. These otherwise fit and healthy women enter the healthcare system and their only problem is a failure to become pregnant. They find themselves trying to negotiate a system des...

journal_title：International journal of clinical practice

authors： Williams M,Green L,Roberts K

更新日期：2010-11-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the most lethal of the common solid malignancies. It is predominantly a disease of the elderly with the median age at diagnosis 68 years. Unfortunately, the majority of patients present with advanced disease whereby palliation is the primary aim of treatment. The elderly have a lo...

journal_title：International journal of clinical practice

authors： Cheong KA,Chrystal K,Harper PG

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Erectile dysfunction (ED) is a common medical condition. In the UK, approximately 2.3 million men suffer from moderate-to-severe ED, many of whom do not consult a healthcare professional about the problem. Phosphodiesterase-type 5 (PDE5) inhibitors have revolutionised treatment for ED and three such drugs ar...

journal_title：International journal of clinical practice

authors： Dinsmore W

更新日期：2009-08-01 00:00:00

abstract：:Spontaneous intramural dissection or intramural haematoma of the oesophagus is an unusual condition and has been recognised as a separate clinical entity. The commonest presenting symptoms are chest pain, dysphagia and haematemesis usually affecting women in their sixties and seventies. Conservative management is usua...

journal_title：International journal of clinical practice

authors： Bandyopadhyay P,Patel CU

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:The available evidence regarding the possible effects of resveratrol on liver function is inconsistent. Therefore, the present meta-analysis was performed to investigate the overall effects of resveratrol supplementation on liver enzymes in adults. METHODS:A systematic and comprehensive search of the online...

journal_title：International journal of clinical practice

authors： Darand M,Farrokhzad A,Ghavami A,Hadi A,Karimi E,Fadel A,Askari G

更新日期：2020-08-31 00:00:00

abstract：AIMS:To describe the mechanisms of action of denosumab, a novel antiresorptive agent, contrasting it with other antiresorptive and anabolic osteoporosis treatments. METHODS:Published papers related to the mechanism of action of approved osteoporosis treatments were sought through MEDLINE searches. FINDINGS:Osteoporot...

journal_title：International journal of clinical practice

authors： Hanley DA,Adachi JD,Bell A,Brown V

更新日期：2012-12-01 00:00:00

abstract：AIM:Real-life studies are needed to confirm the clinical relevance of findings from randomised controlled trials (RCTs). This study aimed to assess the effectiveness and tolerability of vildagliptin add-on vs. other oral antihyperglycaemic drugs (OADs) added to OAD monotherapy in a real-life setting, and to explore the...

journal_title：International journal of clinical practice

authors： Mathieu C,Barnett AH,Brath H,Conget I,de Castro JJ,Göke R,Márquez Rodriguez E,Nilsson PM,Pagkalos E,Penfornis A,Schaper NC,Wangnoo SK,Kothny W,Bader G

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Critically ill patients with coronavirus disease 2019 (COVID-19) were surging and far outnumbered existing beds. AIMS:To describe how to rapidly convert general wards to intensive care units for critically ill patients with COVID-19. MATERIALS AND METHODS:Comprehensive assessment and analysis of available ...

journal_title：International journal of clinical practice

authors： Xiong J,Hu L,Huang S,Li Z,Guo C,Deng J,He M

更新日期：2020-12-17 00:00:00

abstract：AIMS:The aims of this study were to determine the diagnostic yield of a dedicated heart failure diagnosis clinic and the impact of using different guideline recommended N-terminal pro B-type natriuretic peptide (NT-proBNP) referral thresholds on diagnosis and referral patterns. METHODS AND RESULTS:Patients referred by...

journal_title：International journal of clinical practice

authors： Fazal IA,Bhagra SK,Bailey KM,Dermot Neely R,MacGowan GA,Skinner JS

更新日期：2015-11-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the impact of depression and somatic symptoms on treatment outcomes in Korean male patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) attending a routine clinical practice. METHODS:This was a 12-week prospective observational study (n = 80). The Korean ve...

journal_title：International journal of clinical practice

authors： Koh JS,Ko HJ,Wang SM,Cho KJ,Kim JC,Lee SJ,Pae CU

更新日期：2014-04-01 00:00:00

abstract：:We sought to clarify whether impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or both (IFG/IGT) represent the most severe impairment in insulin resistance (IR) and insulin secretion. Among the 159 Chinese subjects, 21 were diagnosed as having IFG, 103 as having IGT and 35 as having both. IR and beta-ce...

journal_title：International journal of clinical practice

authors： Hsieh CH,Kuo SW,Hung YJ,Shen DC,Ho CT,Lian WC,Lee CH,Fan SC,Pei D

更新日期：2005-06-01 00:00:00

abstract：:We report a case of acute myocardial infarction in an HIV-infected patient without significant coronary artery disease (CAD) risk factors. The patient underwent rescue percutaneous transluminal coronary angioplasty (PTCA), with a successful outcome. We presume a possible pathogenetic role of anti-retroviral therapy an...

journal_title：International journal of clinical practice

authors： Saporito F,Micari A,Raffa S,Cerrito M,Micari G,Grassi R

更新日期：2005-03-01 00:00:00

abstract：:Current and upcoming treatment options for premature ejaculation (PE) are of global clinical interest. In 2008, the International Society for Sexual Medicine published an evidence-based definition for PE. While there are no US Food and Drug Administration-approved therapies for PE, the American Urological Association ...

journal_title：International journal of clinical practice

authors： Hellstrom WJ

更新日期：2011-01-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of adult blindness among individuals aged 50 and older in the Western world, with the neovascular form of AMD responsible for the most severe and rapid visual loss. Although monotherapy with currently available treatments can slow the rate of loss of vision i...

journal_title：International journal of clinical practice

authors： Kaiser PK,Do DV

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Antibiotics are widely used and inaccurate or inappropriate prescription of antibiotics causes a significant increase in the prevalence of multidrug-resistant bacterial infections among children. This research aimed to study antibiotic prescriptions in hospitalised paediatric patients and to determine the pr...

journal_title：International journal of clinical practice

authors： Oğuz E,Bebitoğlu BT,Nuhoğlu Ç,Çağ Y,Hodzic A,Temel F,Çırtlık P,Kurtdan Dalkılıç AE

更新日期：2020-10-24 00:00:00

abstract：:A case of alexia without agraphia is presented. It is a rare but classic disconnection syndrome, first described by Dejerine in 1892. Recent advances in modern neuroimaging techniques such as FLAIR MRI can now localise in vivo the site of origin of the syndrome, especially when computerised axial tomogram of the brain...

journal_title：International journal of clinical practice

authors： Imtiaz KE,Nirodi G,Khaleeli AA

更新日期：2001-04-01 00:00:00

abstract：:Pharmacological treatment of hypertension represents a cost-effective way for preventing cardiovascular and renal complications. To benefit maximally from antihypertensive treatment blood pressure (BP) should be brought to below 140/90 mmHg in every hypertensive patient, and even lower (< 130/80 mmHg) if diabetes or r...

journal_title：International journal of clinical practice

authors： Struijker-Boudier HA,Ambrosioni E,Holzgreve H,Laurent S,Mancia G,Ruilope LM,Waeber B

更新日期：2007-09-01 00:00:00

abstract：:Tobacco dependence remains the major preventable cause of early mortality and morbidity in the developed world. The primary reinforcer of the dependence is the nicotine present in tobacco smoke and, for many smokers, successful treatment depends upon breaking this dependence. Until recently, the only specific pharmaco...

journal_title：International journal of clinical practice

authors： Balfour DJ

更新日期：2001-01-01 00:00:00

abstract：:Hyperthyrotropinaemia, in which normal levels of T4 occur in association with raised thyroid stimulating hormone (TSH), is usually picked up on neonatal screening. High TSH level can continue for a long time in some of the cases. There is no consensus concerning the follow-up or treatment plan for hyperthyrotropinaemi...

journal_title：International journal of clinical practice

authors： Demirel F,Bideci A,Camurdan MO,Cinaz P

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:In the setting of an increasing workload for radiologists, this study focuses on the feasibility of skill mixing in breast imaging in a hospital radiology department. METHODS:Two radiological technologists with more than 10 years of experience in performing mammograms were trained in prereading mammograms to s...

journal_title：International journal of clinical practice

authors： van den Biggelaar FJ,Kessels AG,van Engelshoven JM,Flobbe K

更新日期：2010-03-01 00:00:00

abstract：:Graham Jackson introduced the concept that erectile dysfunction was a marker for undiagnosed cardiovascular disease and future events. Unfortunately this had had modest impact on CVD management as ED is not incorporated into current risk calculators. In this paper, we examine recent evidence as to whether ED should be...

journal_title：International journal of clinical practice

authors： Hackett G,Kirby M

更新日期：2018-02-01 00:00:00

abstract：AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...

journal_title：International journal of clinical practice

authors： Drake MJ,MacDiarmid S,Chapple CR,Esen A,Athanasiou S,Cambronero Santos J,Mitcheson D,Herschorn S,Siddiqui E,Huang M,Stoelzel M

更新日期：2017-05-01 00:00:00